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National Institutes of Health


EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT


2023 ANNUAL REPORT OF THE DIVISION OF INTRAMURAL RESEARCH

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     * Pedro Rocha
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     * Mihaela Serpe
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2023 ANNUAL REPORT • CONTENTS

Download the Annual Report as a PDF here: NICHD_DIR_Annual_Report_2023.pdf (PDF,
27 MB)

Click image to view.

About the Image

What is the DIR?
Contact Us
Archive

Board of Scientific Counselors
Scientific Director's Message
Office of the Scientific Director
Office of Education
Office of the Clinical Director
Clinical Trials

Clinical Training Programs

 * NICHD-NIDDK-NIDCR Inter-Institute Endocrine Training Program
 * Pediatric Endocrinology Inter-Institute Training Program
 * Pediatric and Adolescent Gynecology Training Program
 * Reproductive Endocrinology and Infertility Training Program

Administrative Management Branch
Research Animal Management Branch

Scientific Core Facilities

 * Ryan Dale: Bioinformatics and Scientific Programming
 * Ryan Dale: Computer Support Services
 * Vincent Schram: Microscopy and Imaging
 * Forbes Porter: Molecular Genomics Laboratory
 * Ben Feldman: Zebrafish Core

Affinity Groups


A

 * Philip Adams: RNA–Mediated Gene Regulation in the Lyme Disease Pathogen


B

 * Tamás Balla: Phosphoinositide Messengers in Cellular Signaling and
   Trafficking
 * Anirban Banerjee: Structural and Chemical Biology
 * Jeffrey Baron: Regulation of Childhood Growth
 * Peter Basser: Quantitative Imaging and Tissue Sciences
 * Sergey Bezrukov: Biophysics of Large Membrane Channels
 * Juan Bonifacino: Protein Sorting in the Endomembrane System
 * Andres Buonanno: Neuregulin–ErbB and NMDA Receptor Signaling in Neuronal
   Development and Psychiatric Disorders
 * Harold Burgess: Neuronal Circuits Controlling Behavior: Genetic Analysis in
   Zebrafish


C

 * Leonid Chernomordik: Cell Fusion Stages in Osteoclastogenesis: Mechanisms and
   Physiological Role
 * Ajay Chitnis: Building the Zebrafish Lateral Line System
 * Janice Chou: Molecular Genetics of Heritable Human Disorders
 * David Clark: Chromatin Remodeling and Gene Activation
 * Robert Crouch: Physiological, Biochemical, and Molecular-Genetic Events
   Governing the Recognition and Resolution of RNA/DNA Hybrids


D

 * An Dang Do: Investigations of Cellular Stress in Development and Diseases
 * Mary Dasso: Mechanisms of Nuclear Genome Organization and Maintenance
 * Melvin DePamphilis: Regulation of Mammalian Cell Proliferation and
   Differentiation
 * Thomas Dever: Mechanism and Regulation of Eukaryotic Protein Synthesis
 * Rena D’Souza: Molecules and Therapies for Craniofacial and Dental Disorders


F

 * Jeffrey Farrell: Transcriptional Control of Cell Specification and
   Differentiation
 * Douglas Fields: Nervous System Development and Plasticity


G

 * Amir Gandjbakhche: Translational Biophotonics in Developmental Disorders and
   Diseases
 * Catherine Gordon: Predictors of Bone Health in Adolescents and Young Adults


H

 * Alan Hinnebusch: Transcriptional and Translational Regulatory Mechanisms in
   Nutrient Control of Gene Expression
 * Dax Hoffman: Molecular Nature and Functional Role of Dendritic Voltage-Gated
   Ion Channels


K

 * Judith Kassis: Control of Gene Expression during Development


L

 * Sergey Leikin: Extracellular Matrix Disorders: Molecular Mechanisms and
   Treatment Targets
 * Claire Le Pichon: From Axon Damage to Disease: Common Pathways in
   Neurodegeneration
 * Henry Levin: The Biological Impact of Transposable Elements
 * Mary Lilly: Cell Cycle Regulation in Oogenesis
 * Y. Peng Loh: Neurosecretory Proteins in Neuroprotection and Neurodevelopment
 * Jon Lorsch: The Molecular Mechanics of Eukaryotic Translation Initiation
 * Paul Love: Exploring Genes and Signals Regulating Mammalian Hematopoiesis and
   New Approaches to Immunotherapy


M

 * Todd Macfarlan: The Arms Race between Transposable Elements and KRAB-ZFPs and
   its Impact on Mammals
 * Matthias Machner: Virulence Mechanisms of Microbial Pathogens
 * Richard Maraia: RNA Metabolism in Cell Biology, Growth, and Development
 * Leonid Margolis: Immune Activation and Viral Pathogenesis
 * Joan Marini: Genetic Disorders of Bone and Extracellular Matrix
 * Doreen Matthies: High-Resolution Structural Biology of Membrane Protein
   Complexes in Their Native Environment
 * Chris McBain: Hippocampal Interneurons and Their Role in the Control of
   Network Excitability
 * Deborah Merke: Pathophysiology, Genetics, and Treatment of Congenital Adrenal
   Hyperplasia
 * Anil Mukherjee: Childhood Neurodegenerative Lysosomal Storage Disorders


O

 * Keiko Ozato: Gene Regulation in Innate Immunity


P

 * Karel Pacak: Diagnosis, Localization, Pathophysiology, and Molecular Biology
   of Pheochromocytoma and Paraganglioma
 * Timothy Petros: Mechanisms Regulating Fate and Maturation of Forebrain
   GABAergic Interneurons
 * Karl Pfeifer: Molecular Genetics of an Imprinted Gene Cluster on Mouse Distal
   Chromosome 7
 * Forbes Porter: Rare Genetic Disorders of Cholesterol Homeostasis and
   Lysosomal Diseases


R

 * Pedro Rocha: Three-Dimensional Organization of the Genome as a Determinant of
   Cell-Fate Decisions
 * Katherine Rogers: Decoding Developmental Signaling in Vertebrate Embryos
 * Roberto Romero: Mechanisms of Disease in Preterm Labor and Complications of
   Prematurity; Prenatal Diagnosis of Congenital Anomalies
 * Tracey Rouault: Regulation of Mammalian Iron Metabolism and Biogenesis of
   Iron-Sulfur Proteins


S

 * Mihaela Serpe: Mechanisms of Synapse Assembly and Homeostasis
 * Sarah Sheppard: Cellular and Molecular Mechanisms of Lymphatic Disorders
 * Yun-Bo Shi: Thyroid Hormone Regulation of Vertebrate Postembryonic
   Development
 * Alexander Sodt: Modeling the Biophysics of Cellular Membranes
 * Stanko Stojilkovic: Signaling and Secretion in Neuroendocrine Cells
 * Mark Stopfer: Chemosensory Coding and Decoding by Neuron Ensembles
 * Gisela Storz: Regulatory Small RNAs and Small Proteins


T

 * Christina Tatsi: Evaluation of Hypothalamic and Pituitary Disorders
 * Bruce Tromberg: Point of Care and Wearable Biophotonics for Characterizing
   Tissue Composition and Metabolism


W

 * Brant Weinstein: Organ and Tissue Formation during Development
 * Roger Woodgate: Studies on DNA Replication, Repair, and Mutagenesis in
   Eukaryotic and Prokaryotic Cells


Y

 * Jack Yanovski: Physiology, Psychology, and Genetics of Obesity


Z

 * Joshua Zimmerberg: Membrane Interactions Underly Viral Spike Protein
   Porations, Microvesicle Assembly Sites on Umbilical Cord Endothelial Cells,
   and Glioblastoma Cell Migration.

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