www.novozymesonehealth.com Open in urlscan Pro
2620:1ec:bdf::73  Public Scan

Submitted URL: https://menaquingold.com/
Effective URL: https://www.novozymesonehealth.com/ingredients/menaquingold
Submission: On August 10 via api from US — Scanned from DE

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 * An invitation to create an aspirational solution
   
   >

 * MenaquinGold™


MENAQUINGOLD™


The future is golden

Introducing MenaquinGold™, our natural vitamin K2 produced utilizing a patented
chickpea fermentation process in our soy-free, non-GMO manufacturing facilities.
With an FDA issued GRAS ‘No objection letter’ and supported by scientific
research and clinical trials, MenaquinGold™ is a key ingredient to building a
healthier future.


GOOD FOR MORE THAN YOU THINK POSSIBLE


Vitamin K2 has been associated with health benefits within several areas. The
indications with the most substantiated evidence are bone health1 and heart
health,2,3,4 but emerging science indicates promising results related to sports
performance and nerve health.5,6,7

 

BINDS CALCIUM

Vitamin K2-7 is observed to activate the bone protein osteocalcin, which is
essential to bind calcium effectively to the bone matrix.1

HEART HEALTH BENEFITS

Vitamin K2-7 has been associated with heart health benefits.9,10,2,3

NERVE AND SPORTS HEALTH BENEFITS

Proprietary research on MenaquinGold™ suggests vitamin K2-7 may provide health
benefits in relation to nerve health and sports health.


WHAT IS VITAMIN K2?


Vitamin K is a collective term for like, fat-soluble compounds. There are two
kinds of vitamin K: vitamin K1 (phylloquinone or phytonadione) and vitamin K2
(menaquinone). As vitamin K2 can differ in number side chains of the molecule
you might come across names as vitamin K2-4 (four side groups), also called
MK-4, (for menaquinone K-4) or K2-7 (seven side groups) also called MK-7.

Learn more about the science of K2


FERMENTING…CHICKPEAS!
MANUFACTURING MENAQUINGOLD™ WITH ZERO SOY


We’ve always believed it’s the small things that can make a big difference, and
chickpeas are a prime example! We know from experience that allergies and purity
concerns are top of mind for consumers, so ensuring our MenaquinGold™ production
facilities are soy-free has been of utmost importance.

Our process of submerged fermentation with a Bacillus liciniformis strain is
patented and thanks to our proprietary extraction method, we have good stability
records by preventing the accumulation of metabolites that affect the long-term
stability of vitamin K2-7.

MenaquinGold™ is manufactured in-house at our GMP-certified plant near Mumbai,
India. The world-class facility is equipped with the highest quality
technologies and equipment, as you would expect from Novozymes, the world’s
leading enzyme producer. The facility is cGMP, HACCP, and ISO 22000 certified.

Manufacturing our active health ingredients


CLASSIFIED AS GRAS WITH ‘NO OBJECTION' RESPONSE FROM THE FDA


Novozymes OneHealth is proud to announce that the FDA has issued a GRAS
(Generally Recognized As Safe) 'No objection' letter for MenaquinGold™. This
means the FDA has no objection to the GRAS self-affirmation notification our
scientists established and submitted. Our FDA GRAS status is for children (GRAS
Notification GRN000887).




APPLICATIONS FLOURISH WITH MENAQUINGOLD™ WITH FLEXIBLE FORMULATIONS


MenaquinGold™ can be formulated as a stand-alone input or in combination with
other functional ingredients. Our team can assist you to meet the growing demand
for products fortified with vitamin K2-7.

MenaquinGold™ is available across multiple product grades and concentrations –
so you can add it to the dosage form of your choice. Our powder grade is
suitable for most dry blends including capsules and tablets without alkaline or
aggressive components. Our water-soluble product is perfect for applications
such as sachets, beverage powder blends, and liquids. Granules are also
available for tablet and capsule applications. Finally, we have MenaquinGold™ in
an MCT oil form.




LET'S TALK


At Novozymes OneHealth our business and culture is focused on creating deep
partnerships to collaborate on unique products that make a real difference to
the lives of consumers. Sound good? To find out more contact us.




DISCOVER A WORLD OF K2 SCIENCE AND APPLICATIONS


CLINICAL STUDYProtective and immune health2023.10.03


WHITEPAPER ON VITAMIN K2 INSUFFICIENCY, THE DIFFERENT TYPES OF K2 AND THEIR
BENEFITS


SCIENCE & INNOVATIONProtective and immune health2023.09.22


WEBINAR: K2-7, A MULTITASKING VITAMIN



VITAMIN K2 AND YOU



WHAT YOU NEED TO KNOW ABOUT VITAMIN K2



VITAMIN K2: GOOD FOR MORE THAN YOU THINK POSSIBLE



DISCOVER THE UNTAPPED POTENTIAL OF A NOVEL VITAMIN FOR MULTIPLE LIFESTYLE HEALTH
CHALLENGES


Science is pushing the boundaries of what’s possible in treating health
conditions, as well as in preventative health care. A key market booming from
this combination of scientific innovation and consumer activism, is
nutraceuticals.

The number of Americans who use dietary supplements is growing across age groups
and at present, research suggests over 70% of Americans believe dietary
supplements play an important part in lifestyle change.

One nutraceutical that increasingly gets attention is Vitamin K2.

We keep our finger on the market’s pulse and we’ve invested in our own research.
Let us share our findings with you. You'll be ahead of the competition and one
step closer to meeting the needs of consumers.

Current trends in lifestyle-related nutraceuticals

 1.  Van Summeren, M., Braam, L., Lilien, M., Schurgers, L., Kuis, W., &
     Vermeer, C. (2009). The effect of menaquinone-7 (vitamin K2)
     supplementation on osteocalcin carboxylation in healthy prepubertal
     children. British Journal of Nutrition, 102(8), 1171-1178.
     doi:10.1017/S0007114509382100

 2.  Geleijnse, J. M., Vermeer, C., Grobbee, D. E., Schurgers, L. J., Knapen, M.
     H., van der Meer, I. M., Hofman, A., & Witteman, J. C. (2004). Dietary
     intake of menaquinone is associated with a reduced risk of coronary heart
     disease: the Rotterdam Study. The Journal of nutrition, 134(11), 3100–3105.
     https://doi.org/10.1093/jn/134.11.3100

 3.  Gast, G. C., de Roos, N. M., Sluijs, I., Bots, M. L., Beulens, J. W.,
     Geleijnse, J. M., Witteman, J. C., Grobbee, D. E., Peeters, P. H., & van
     der Schouw, Y. T. (2009). A high menaquinone intake reduces the incidence
     of coronary heart disease. Nutrition, metabolism, and cardiovascular
     diseases: NMCD, 19(7), 504–510.
     https://doi.org/10.1016/j.numecd.2008.10.004

 4.  Mehta DS, Vaidya RA, Dound YA et al. Therapeutic Activity and Safety of
     Vitamin K2-7 in Muscle Cramps: An Interventional Case- Series. The Indian
     Practitioner 2010; May: 287-291.

 5.  Kulkarni VK, Upase DU, Dound YA et al. The effect of vitamin K2-7 in
     peripheral neuropathy due to vitamin B12 deficiency and diabetes mellitus:
     A Preliminary Study, The Indian Practitioner 2013; 66:625-629

 6.  Choi, H. J., Yu, J., Choi, H., An, J. H., Kim, S. W., Park, K. S., Jang, H.
     C., Kim, S. Y., & Shin, C. S. (2011). Vitamin K2 supplementation improves
     insulin sensitivity via osteocalcin metabolism: a placebo-controlled trial.
     Diabetes care, 34(9), e147. https://doi.org/10.2337/dc11-0551

 7.  Beulens, J. W., van der A, D. L., Grobbee, D. E., Sluijs, I., Spijkerman,
     A. M., & van der Schouw, Y. T. (2010). Dietary phylloquinone and
     menaquinones intakes and risk of type 2 diabetes. Diabetes care, 33(8),
     1699–1705. https://doi.org/10.2337/dc09-2302

 8.  Schurgers, L. J., Teunissen, K. J., Hamulyák, K., Knapen, M. H., Vik, H., &
     Vermeer, C. (2007). Vitamin K-containing dietary supplements: comparison of
     synthetic vitamin K1 and natto-derived menaquinone-7. Blood, 109(8),
     3279–3283. https://doi.org/10.1182/blood-2006-08-040709

 9.  Van Summeren, M., Braam, L., Lilien, M., Schurgers, L., Kuis, W., &
     Vermeer, C. (2009). The effect of menaquinone-7 (vitamin K2)
     supplementation on osteocalcin carboxylation in healthy prepubertal
     children. British Journal of Nutrition, 102(8), 1171-1178.
     doi:10.1017/S0007114509382100

 10. https://doi.org/10.1248/jhs.46.317

 11. Kaneki, M., Hodges, S. J., Hosoi, T., Fujiwara, S., Lyons, A., Crean, S.
     J., Ishida, N., Nakagawa, M., Takechi, M., Sano, Y., Mizuno, Y., Hoshino,
     S., Miyao, M., Inoue, S., Horiki, K., Shiraki, M., Ouchi, Y., & Orimo, H.
     (2001). Japanese fermented soybean food as the major determinant of the
     large geographic difference in circulating levels of vitamin K2: possible
     implications for hip-fracture risk. Nutrition (Burbank, Los Angeles County,
     Calif.), 17(4), 315–321. https://doi.org/10.1016/s0899-9007(00)00554-2

 12. Geleijnse, J. M., Vermeer, C., Grobbee, D. E., Schurgers, L. J., Knapen, M.
     H., van der Meer, I. M., Hofman, A., & Witteman, J. C. (2004). Dietary
     intake of menaquinone is associated with a reduced risk of coronary heart
     disease: the Rotterdam Study. The Journal of nutrition, 134(11), 3100–3105.
     https://doi.org/10.1093/jn/134.11.3100

 13. Gast, G. C., de Roos, N. M., Sluijs, I., Bots, M. L., Beulens, J. W.,
     Geleijnse, J. M., Witteman, J. C., Grobbee, D. E., Peeters, P. H., & van
     der Schouw, Y. T. (2009). A high menaquinone intake reduces the incidence
     of coronary heart disease. Nutrition, metabolism, and cardiovascular
     diseases: NMCD, 19(7), 504–510.
     https://doi.org/10.1016/j.numecd.2008.10.004

 14. BCG commissioned report

 15. BCG commissioned report

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