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Submitted URL: https://menaquingold.com/
Effective URL: https://www.novozymesonehealth.com/ingredients/menaquingold
Submission: On August 10 via api from US — Scanned from DE
Effective URL: https://www.novozymesonehealth.com/ingredients/menaquingold
Submission: On August 10 via api from US — Scanned from DE
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Settings Accept all powered by: Cookie Information Functional Marketing Part of * Health categories Our science Discover the innovative combination of consumer insights, clinical research and data science driving our growing product portfolio. Find out more Gastrointestinal health Empowering people to take control of their gut and digestive health. Brain health Targeting the gut to maintain mental wellness, optimize brain functions, and support healthy ageing in the brain Oral health Improving quality of life through positively influencing the oral microbiome Protective & immune health Helping to support exposed immune systems Let’s partner up Want to discuss business models of the future, co-branding, clinical studies and studies or Marketing and collateral? Contact Us * Solutions Solutions Clinically proven, unique combinations of probiotics, enzymes, and bioactives targeting specific health indications, our One-in-a trillion solutions. Our One-in-a-trillion mission BioFresh™ 4+ An enzyme combination eliminating oral malodor for up to 4 hours. BioFresh™ Clean An enzyme combination that keeps teeth clean by naturally removing and reducing oral biofilm. IBme™ A probiotic designed to reduce symptoms of gastrointestinal discomfort. IBme™ Dual A probiotic combination designed to target the gut-brain axis ProbioBrain™ A probiotic for mental wellness. Pylopass™ A postbiotic that can help reduce the load of H. pylori in the stomach. SmartGuard™ A safe and gentle probiotic developed to help limit daily lead absorption. * Ingredients Ingredients Premium ingredients backed by clinical trials across multiple areas of human health. Learn more MenaquinGold™ A natural, soy-free vitamin K2 for a healthier future. Probiotic Spores Strengthen your probiotic portfolio with true survivors; HU58™, SC208™ and SC109™ * Science & Insights * News & Events * About us Our Story We are on a journey to deliver clinically proven, targeted biological solutions of probiotics, enzymes, and other bio-actives. Culture Playbook Our company culture is at the core of how we achieve success. Finding solutions to help consumers live better, healthier lives takes passion, collaboration, empathy and transparency. Want to change the world? Read this playbook. People & Careers Take a the next giant leap in your career and join our talented team. Find out more about the exciting opportunities available at Novozymes OneHealth. Partner with us Ready to start on your own One-in-a-trillion journey? Like you, we’re passionate about making a difference in consumer health and well-being. Meet our brands OneHealth's striking brands have business models as innovative as our products. Enter markets quickly with recognized brands and expert support. Learn more * Health categories Back * Gastrointestinal health * Brain health * Oral health * Protective & immune health Our science Discover the innovative combination of consumer insights, clinical research and data science driving our growing product portfolio. Find out more Let’s partner up Want to discuss business models of the future, co-branding, clinical studies and studies or Marketing and collateral? Contact Us * Solutions Back * BioFresh™ 4+ * BioFresh™ Clean * IBme™ * IBme™ Dual * ProbioBrain™ * Pylopass™ * SmartGuard™ Solutions Clinically proven, unique combinations of probiotics, enzymes, and bioactives targeting specific health indications, our One-in-a trillion solutions. Our One-in-a-trillion mission * Ingredients Back * MenaquinGold™ * Probiotic Spores Ingredients Premium ingredients backed by clinical trials across multiple areas of human health. Learn more * Science & Insights * News & Events * About us Back * Our Story * Culture Playbook * People & Careers * Partner with us Meet our brands OneHealth's striking brands have business models as innovative as our products. Enter markets quickly with recognized brands and expert support. Learn more * An invitation to create an aspirational solution > * MenaquinGold™ MENAQUINGOLD™ The future is golden Introducing MenaquinGold™, our natural vitamin K2 produced utilizing a patented chickpea fermentation process in our soy-free, non-GMO manufacturing facilities. With an FDA issued GRAS ‘No objection letter’ and supported by scientific research and clinical trials, MenaquinGold™ is a key ingredient to building a healthier future. GOOD FOR MORE THAN YOU THINK POSSIBLE Vitamin K2 has been associated with health benefits within several areas. The indications with the most substantiated evidence are bone health1 and heart health,2,3,4 but emerging science indicates promising results related to sports performance and nerve health.5,6,7 BINDS CALCIUM Vitamin K2-7 is observed to activate the bone protein osteocalcin, which is essential to bind calcium effectively to the bone matrix.1 HEART HEALTH BENEFITS Vitamin K2-7 has been associated with heart health benefits.9,10,2,3 NERVE AND SPORTS HEALTH BENEFITS Proprietary research on MenaquinGold™ suggests vitamin K2-7 may provide health benefits in relation to nerve health and sports health. WHAT IS VITAMIN K2? Vitamin K is a collective term for like, fat-soluble compounds. There are two kinds of vitamin K: vitamin K1 (phylloquinone or phytonadione) and vitamin K2 (menaquinone). As vitamin K2 can differ in number side chains of the molecule you might come across names as vitamin K2-4 (four side groups), also called MK-4, (for menaquinone K-4) or K2-7 (seven side groups) also called MK-7. Learn more about the science of K2 FERMENTING…CHICKPEAS! MANUFACTURING MENAQUINGOLD™ WITH ZERO SOY We’ve always believed it’s the small things that can make a big difference, and chickpeas are a prime example! We know from experience that allergies and purity concerns are top of mind for consumers, so ensuring our MenaquinGold™ production facilities are soy-free has been of utmost importance. Our process of submerged fermentation with a Bacillus liciniformis strain is patented and thanks to our proprietary extraction method, we have good stability records by preventing the accumulation of metabolites that affect the long-term stability of vitamin K2-7. MenaquinGold™ is manufactured in-house at our GMP-certified plant near Mumbai, India. The world-class facility is equipped with the highest quality technologies and equipment, as you would expect from Novozymes, the world’s leading enzyme producer. The facility is cGMP, HACCP, and ISO 22000 certified. Manufacturing our active health ingredients CLASSIFIED AS GRAS WITH ‘NO OBJECTION' RESPONSE FROM THE FDA Novozymes OneHealth is proud to announce that the FDA has issued a GRAS (Generally Recognized As Safe) 'No objection' letter for MenaquinGold™. This means the FDA has no objection to the GRAS self-affirmation notification our scientists established and submitted. Our FDA GRAS status is for children (GRAS Notification GRN000887). APPLICATIONS FLOURISH WITH MENAQUINGOLD™ WITH FLEXIBLE FORMULATIONS MenaquinGold™ can be formulated as a stand-alone input or in combination with other functional ingredients. Our team can assist you to meet the growing demand for products fortified with vitamin K2-7. MenaquinGold™ is available across multiple product grades and concentrations – so you can add it to the dosage form of your choice. Our powder grade is suitable for most dry blends including capsules and tablets without alkaline or aggressive components. Our water-soluble product is perfect for applications such as sachets, beverage powder blends, and liquids. Granules are also available for tablet and capsule applications. Finally, we have MenaquinGold™ in an MCT oil form. LET'S TALK At Novozymes OneHealth our business and culture is focused on creating deep partnerships to collaborate on unique products that make a real difference to the lives of consumers. Sound good? To find out more contact us. DISCOVER A WORLD OF K2 SCIENCE AND APPLICATIONS CLINICAL STUDYProtective and immune health2023.10.03 WHITEPAPER ON VITAMIN K2 INSUFFICIENCY, THE DIFFERENT TYPES OF K2 AND THEIR BENEFITS SCIENCE & INNOVATIONProtective and immune health2023.09.22 WEBINAR: K2-7, A MULTITASKING VITAMIN VITAMIN K2 AND YOU WHAT YOU NEED TO KNOW ABOUT VITAMIN K2 VITAMIN K2: GOOD FOR MORE THAN YOU THINK POSSIBLE DISCOVER THE UNTAPPED POTENTIAL OF A NOVEL VITAMIN FOR MULTIPLE LIFESTYLE HEALTH CHALLENGES Science is pushing the boundaries of what’s possible in treating health conditions, as well as in preventative health care. A key market booming from this combination of scientific innovation and consumer activism, is nutraceuticals. The number of Americans who use dietary supplements is growing across age groups and at present, research suggests over 70% of Americans believe dietary supplements play an important part in lifestyle change. One nutraceutical that increasingly gets attention is Vitamin K2. We keep our finger on the market’s pulse and we’ve invested in our own research. Let us share our findings with you. You'll be ahead of the competition and one step closer to meeting the needs of consumers. Current trends in lifestyle-related nutraceuticals 1. Van Summeren, M., Braam, L., Lilien, M., Schurgers, L., Kuis, W., & Vermeer, C. (2009). The effect of menaquinone-7 (vitamin K2) supplementation on osteocalcin carboxylation in healthy prepubertal children. British Journal of Nutrition, 102(8), 1171-1178. doi:10.1017/S0007114509382100 2. Geleijnse, J. M., Vermeer, C., Grobbee, D. E., Schurgers, L. J., Knapen, M. H., van der Meer, I. M., Hofman, A., & Witteman, J. C. (2004). Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease: the Rotterdam Study. The Journal of nutrition, 134(11), 3100–3105. https://doi.org/10.1093/jn/134.11.3100 3. Gast, G. C., de Roos, N. M., Sluijs, I., Bots, M. L., Beulens, J. W., Geleijnse, J. M., Witteman, J. C., Grobbee, D. E., Peeters, P. H., & van der Schouw, Y. T. (2009). A high menaquinone intake reduces the incidence of coronary heart disease. Nutrition, metabolism, and cardiovascular diseases: NMCD, 19(7), 504–510. https://doi.org/10.1016/j.numecd.2008.10.004 4. Mehta DS, Vaidya RA, Dound YA et al. Therapeutic Activity and Safety of Vitamin K2-7 in Muscle Cramps: An Interventional Case- Series. The Indian Practitioner 2010; May: 287-291. 5. Kulkarni VK, Upase DU, Dound YA et al. The effect of vitamin K2-7 in peripheral neuropathy due to vitamin B12 deficiency and diabetes mellitus: A Preliminary Study, The Indian Practitioner 2013; 66:625-629 6. Choi, H. J., Yu, J., Choi, H., An, J. H., Kim, S. W., Park, K. S., Jang, H. C., Kim, S. Y., & Shin, C. S. (2011). Vitamin K2 supplementation improves insulin sensitivity via osteocalcin metabolism: a placebo-controlled trial. Diabetes care, 34(9), e147. https://doi.org/10.2337/dc11-0551 7. Beulens, J. W., van der A, D. L., Grobbee, D. E., Sluijs, I., Spijkerman, A. M., & van der Schouw, Y. T. (2010). Dietary phylloquinone and menaquinones intakes and risk of type 2 diabetes. Diabetes care, 33(8), 1699–1705. https://doi.org/10.2337/dc09-2302 8. Schurgers, L. J., Teunissen, K. J., Hamulyák, K., Knapen, M. H., Vik, H., & Vermeer, C. (2007). Vitamin K-containing dietary supplements: comparison of synthetic vitamin K1 and natto-derived menaquinone-7. Blood, 109(8), 3279–3283. https://doi.org/10.1182/blood-2006-08-040709 9. Van Summeren, M., Braam, L., Lilien, M., Schurgers, L., Kuis, W., & Vermeer, C. (2009). The effect of menaquinone-7 (vitamin K2) supplementation on osteocalcin carboxylation in healthy prepubertal children. British Journal of Nutrition, 102(8), 1171-1178. doi:10.1017/S0007114509382100 10. https://doi.org/10.1248/jhs.46.317 11. Kaneki, M., Hodges, S. J., Hosoi, T., Fujiwara, S., Lyons, A., Crean, S. J., Ishida, N., Nakagawa, M., Takechi, M., Sano, Y., Mizuno, Y., Hoshino, S., Miyao, M., Inoue, S., Horiki, K., Shiraki, M., Ouchi, Y., & Orimo, H. (2001). Japanese fermented soybean food as the major determinant of the large geographic difference in circulating levels of vitamin K2: possible implications for hip-fracture risk. Nutrition (Burbank, Los Angeles County, Calif.), 17(4), 315–321. https://doi.org/10.1016/s0899-9007(00)00554-2 12. Geleijnse, J. M., Vermeer, C., Grobbee, D. E., Schurgers, L. J., Knapen, M. H., van der Meer, I. M., Hofman, A., & Witteman, J. C. (2004). Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease: the Rotterdam Study. The Journal of nutrition, 134(11), 3100–3105. https://doi.org/10.1093/jn/134.11.3100 13. Gast, G. C., de Roos, N. M., Sluijs, I., Bots, M. L., Beulens, J. W., Geleijnse, J. M., Witteman, J. C., Grobbee, D. E., Peeters, P. H., & van der Schouw, Y. T. (2009). A high menaquinone intake reduces the incidence of coronary heart disease. Nutrition, metabolism, and cardiovascular diseases: NMCD, 19(7), 504–510. https://doi.org/10.1016/j.numecd.2008.10.004 14. BCG commissioned report 15. BCG commissioned report Disclaimer The communication is intended for business-to-business information and not for the final consumer. These products are not intended for use to diagnose, treat, cure or prevent any disease. The statements on this website have not been evaluated by any regulatory authority, unless specifically mentioned. 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