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News in brief


BRIGHTSEED PARTNERS WITH KALLYOPE TO EXPLORE BIOACTIVES FOR GUT-BRAIN AND WEIGHT
MANAGEMENT

By Stephen Daniells contact

28-Jul-2022 - Last updated on 28-Jul-2022 at 21:08 GMT

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© bymuratdeniz / Getty Images

Related tags: Artificial intelligence, phytonutrients


AI-phytonutrient pioneers Brightseed have entered a strategic research
collaboration to screen plant compounds with biotech company Kallyope to
identify potential weight loss and glucose control therapeutics.

Created by Lee Chae, PhD., Brightseed’s co-founder and CTO, the Forager platform
systematically identifies natural bioactives and maps their connection to human
health benefits.

To date, Forager has mapped more than two million plant compounds – 20 times
more than existing scientific literature – and dozens are in various stages of
validation across multiple health territories, including metabolic health,
digestive health, cognitive health, sugar management, maternal health, and
immunity.

The research collaboration will use Brightseed’s bioactives insights and the
Kallyope Klarity platform to leverage integrated end-to-end capabilities to
identify candidate compounds that act on the gut-brain axis to target weight
management and glucose control.

The partnership marks Brightseed’s first foray into the therapeutics space,
having already established notable partnerships with the likes of Danone ,
Pharmavite , Ocean Spray , and ofi (olam food ingredients) .

According to the release, Kallyope has rights to derivatize and develop
therapeutics in humans any early-stage identification of potential bioactive
candidates. Both companies will share the rights to consumer applications of
identified compounds.

“This collaboration brings together two leading, diverse technological platforms
and teams for the discovery of novel consumer products that may have therapeutic
benefits for Type 2 diabetes and obesity,” said Jay Galeota, president and CEO,
Kallyope.

“We are excited to have the opportunity to work with Brightseed, whose
capabilities are highly synergistic with our lead metabolism therapeutics
program and deep drug discovery and development expertise.”





Jim Flatt, co-founder and CEO, Brightseed, stated: “Seventy-five percent of our
current healthcare spending in the U.S. goes towards treating chronic health
conditions that severely impair the quality of life of millions of people. We
need to reimagine more scalable approaches to combat the scourge of diet-induced
chronic conditions.

“Kallyope is one of the visionary pharmaceutical companies that recognize the
need to develop health products that can prevent or reduce the risk of certain
chronic diseases. Historically, nature has provided the majority of small
molecules that are used to inform our medicines. In partnership with Kallyope’s
high value gut-brain axis biological targets and technology platform, we will
discover the next generation of natural bioactives to improve health and reduce
the incidence of diet-related chronic disease.”



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