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CHINESE COMPANY UNDER CONGRESSIONAL SCRUTINY MAKES KEY U.S. DRUGS

Lawmakers raising national security concerns and seeking to disconnect a major
Chinese firm from U.S. pharmaceutical interests have rattled the biotech
industry. The firm is deeply involved in development and manufacturing of
crucial therapies for cancer, cystic fibrosis, H.I.V. and other illnesses.

A WuXi Biologics facility in Wuxi, China. WuXi AppTec and an affiliated company,
WuXi Biologics, have received millions of dollars in tax incentives to build
sprawling research and manufacturing sites in Massachusetts and
Delaware.Credit...Imaginechina Limited, via Alamy


CHINESE COMPANY UNDER CONGRESSIONAL SCRUTINY MAKES KEY U.S. DRUGS

Lawmakers raising national security concerns and seeking to disconnect a major
Chinese firm from U.S. pharmaceutical interests have rattled the biotech
industry. The firm is deeply involved in development and manufacturing of
crucial therapies for cancer, cystic fibrosis, H.I.V. and other illnesses.

A WuXi Biologics facility in Wuxi, China. WuXi AppTec and an affiliated company,
WuXi Biologics, have received millions of dollars in tax incentives to build
sprawling research and manufacturing sites in Massachusetts and
Delaware.Credit...Imaginechina Limited, via Alamy

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By Christina Jewett

 * April 15, 2024

阅读简体中文版閱讀繁體中文版

A Chinese company targeted by members of Congress over potential ties to the
Chinese government makes blockbuster drugs for the American market that have
been hailed as advances in the treatment of cancers, obesity and debilitating
illnesses like cystic fibrosis.

WuXi AppTec is one of several companies that lawmakers have identified as
potential threats to the security of individual Americans’ genetic information
and U.S. intellectual property. A Senate committee approved a bill in March that
aides say is intended to push U.S. companies away from doing business with them.

But lawmakers discussing the bill in the Senate and the House have said almost
nothing in hearings about the vast scope of work that WuXi does for the U.S.
biotech and pharmaceutical industries — and patients. A New York Times review of
hundreds of pages of records worldwide shows that WuXi is heavily embedded in
the U.S. medicine chest, making some or all of the main ingredients for
multibillion-dollar therapies that are highly sought to treat cancers like some
types of leukemia and lymphoma as well as obesity and H.I.V.

The Congressional spotlight on the company has rattled the pharmaceutical
industry, which is already struggling with widespread drug shortages now at a
20-year high. Some biotech executives have pushed back, trying to impress on
Congress that a sudden decoupling could take some drugs out of the pipeline for
years.



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WuXi AppTec and an affiliated company, WuXi Biologics grew rapidly, offering
services to major U.S. drugmakers that were seeking to shed costs and had
shifted most manufacturing overseas in the last several decades.

WuXi companies developed a reputation for low-cost and reliable work by
thousands of chemists who could create new molecules and operate complex
equipment to make them in bulk. By one estimate, WuXi has been involved in
developing one-fourth of the drugs used in the United States. WuXi AppTec
reported earning about $3.6 billion in revenue for its U.S. work.

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Christina Jewett covers the Food and Drug Administration, which means keeping a
close eye on drugs, medical devices, food safety and tobacco policy. More about
Christina Jewett

A version of this article appears in print on April 16, 2024, Section A, Page 1
of the New York edition with the headline: Chinese Firm Is Key Maker Of U.S.
Drugs. Order Reprints | Today’s Paper | Subscribe
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