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Upstream

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 * Bioreactors
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RECENT IN UPSTREAM

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Bispecific Antibodies Unleashed
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Bispecific Antibodies UnleashedBispecific Antibodies Unleashed
byBPI Contributor
Nov 2, 2023
1 Min Read
Working Toward an AAV Platform: Challenges, Threats, and Opportunities
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Working Toward an AAV Platform: Challenges, Threats, and OpportunitiesWorking
Toward an AAV Platform: Challenges, Threats, and Opportunities
byMégane Denu, Quentin Bazotand 1 more
Oct 20, 2023
Downstream

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 * Chromatography
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RECENT IN DOWNSTREAM

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A Scalable Single-Use Two-Step Plasmid Purification Process
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A Scalable Single-Use Two-Step Plasmid Purification ProcessA Scalable Single-Use
Two-Step Plasmid Purification Process
byBPI Contributor
Nov 3, 2023
20 Min View
Minimizing Lentiviral Vector Loss During the Purification Process Using an
Innovative Nanofiber Adsorbent
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Minimizing Lentiviral Vector Loss During the Purification Process Using an
Innovative Nanofiber AdsorbentMinimizing Lentiviral Vector Loss During the
Purification Process Using an Innovative Nanofiber Adsorbent
byBPI Contributor
Oct 31, 2023
20 Min View
Manufacturing

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 * Biosimilars
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RECENT IN MANUFACTURING

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Bioprocess Insider
Breyanzi: BMS seeking to expand outreach of lymphoma therapyBreyanzi: BMS
seeking to expand outreach of lymphoma therapy
byJosh Abbott
Aug 22, 2024
3 Min Read
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Bioprocess Insider
Fujifilm expands UK manufacturing space with one eye on the futureFujifilm
expands UK manufacturing space with one eye on the future
byJosh Abbott
Aug 22, 2024
2 Min Read
Analytical

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 * QA/QC
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RECENT IN ANALYTICAL

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Test - Juan - Article
Analytical
Test - Juan - ArticleTest - Juan - Article
byAdrianna Milewska
May 3, 2024
1 Min Read
The Key Role of Analytical Methods in Technology Transfer
Sponsored Content
The Key Role of Analytical Methods in Technology TransferThe Key Role of
Analytical Methods in Technology Transfer
byOlena Chervonenko
Oct 17, 2023
Business

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Bioprocess Insider
Key strategies for effective technology evaluationKey strategies for effective
technology evaluation
byKim Bennett
Aug 8, 2024
2 Min Read
Resilience logo
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Built to Serve Innovation: A Briefing on Commercial Readiness at ResilienceBuilt
to Serve Innovation: A Briefing on Commercial Readiness at Resilience
byBPI Contributor
Jun 25, 2024
15 Min View
Therapeutic Modalities

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RECENT IN THERAPEUTIC MODALITIES

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Bioprocess Insider
Biomanufacturing in space accelerating therapy development on
EarthBiomanufacturing in space accelerating therapy development on Earth
byJosh Abbott
Jul 24, 2024
3 Min Read
DNA Synthesis: Chemical, Enzymatic, or Both?
Therapeutic Modalities
DNA Synthesis: Chemical, Enzymatic, or Both?DNA Synthesis: Chemical, Enzymatic,
or Both?
byMark Behlke
Oct 20, 2023
BioProcess Insider

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Upstream & Downstream Processing
Bioprocessing Q3: After 18 challenging months, is the worst behind?Bioprocessing
Q3: After 18 challenging months, is the worst behind?
byDan Stanton
Oct 24, 2024
4 Min Read
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Therapeutic Class
How and why AstraZeneca’s oncology eyes turned to cell therapiesHow and why
AstraZeneca’s oncology eyes turned to cell therapies
byDan Stanton
Oct 18, 2024
4 Min Read




INSIDER NEWS


BIOPROCESSING Q3: AFTER 18 CHALLENGING MONTHS, IS THE WORST BEHIND?

Oct 24, 2024


SURVIVING BIOSECURE: US COMPANIES MUST PREPARE TO AVOID DISRUPTION

Oct 23, 2024


INVESTORS PRIORITIZE EFFICACY IN THE CGT BIZ, EXPERTS SAY

Oct 23, 2024


LETTER URGES FTC TO BLOCK NOVO’S $16.5BN CATALENT PURCHASE

Oct 18, 2024
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Vaccines


THE POWER OF UNIVERSAL VACCINES IN THE FIGHT AGAINST BIOLOGICAL WARFARE


THE POWER OF UNIVERSAL VACCINES IN THE FIGHT AGAINST BIOLOGICAL WARFARE

Sep 1, 2024
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Bioreactors
Lessons in Bioreactor Scale-Up: Part 3 — Experimental Determination and
Application of Oxygen Mass- Transfer Rate, Mass-Transfer Coefficient, and
Oxygen-Uptake Rate
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Application of Oxygen Mass- Transfer Rate, Mass-Transfer Coefficient, and
Oxygen-Uptake Rate

Sep 9, 2024

Continuous Bioprocessing
Controlling Integrated, Continuous Processes: Real-Time Monitoring with
Feed-Back and Feed-Forward Controls Enables Synchronization and Enhances
Robustness
Controlling Integrated, Continuous Processes: Real-Time Monitoring with
Feed-Back and Feed-Forward Controls Enables Synchronization and Enhances
Robustness

Sep 23, 2024




BIOPROCESS INSIDER DAILY - BIOTECH WEEK BOSTON

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Therapeutic Class
How and why AstraZeneca’s oncology eyes turned to cell therapies

Cell therapies will play an increasingly important position in AstraZeneca’s
broad oncology pipeline, an SVP told delegates at Biotech Week Boston (BWB) last
month.

RegulationsSize matters when navigating BIOSECURE, says consultant

Smaller innovators are more likely to be upended by US legislation aimed at
restricting working with China-based CDMOs like WuXi Biologics, according to
Latham Biopharm.

Therapeutic ClassVertex adds Lonza to cautious Casgevy commercial network

Vertex says finding the sweet spot in manufacturing capacity is key to ensuring
the successful rollout of sickle cell gene therapy Casgevy (exagamglogene
autotemcel).

Global MarketsWhite House OSTP: ‘Whether Harris or Trump, biomanufacturing is
bipartisan’

A President Biden Executive Order supporting homegrown biomanufacturing will
remain in place whoever wins in November, White House OSTP assistant director
Sarah Glaven told Biotech Week Boston delegates.


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Upstream Processing

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Expression Platforms
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Jul 31, 2024

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Bioreactors
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Empowering Biologic Breakthroughs: Transforming Tomorrow’s Healthcare Landscape
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Downstream Processing

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Purification Success
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Navigating Biotherapeutic Complexity: Tailored Chromatography Resins to Enable
Purification Success
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Manufacturing

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eBook: Drug Delivery — New Formats for Novel Biopharmaceuticals

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Information Technology
Buffer Design for Biopharmaceutical Processes: An Online Tool for Designing and
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Jun 19, 2024


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Information Technology
Keys to Successful Technology Transfer
Keys to Successful Technology Transfer

Jun 12, 2024


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Analytical

Cell Therapies
Analytical Considerations for Gene-Modified Hematopoietic Stem and Progenitor
Cell Therapies: Part 1 — In-Process and Drug Product Control
Analytical Considerations for Gene-Modified Hematopoietic Stem and Progenitor
Cell Therapies: Part 1 — In-Process and Drug Product Control
QA/QC
Practical Applications of Process Capability Indices in the Biopharmaceutical
Industry: A Simulation-Based Study
Practical Applications of Process Capability Indices in the Biopharmaceutical
Industry: A Simulation-Based Study

Corrective and preventive actions
QA/QC
Determining Sample Size for Demonstrating Zero Failures: Ensuring the
Effectiveness of Corrective and Preventive Actions
Determining Sample Size for Demonstrating Zero Failures: Ensuring the
Effectiveness of Corrective and Preventive Actions

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Business

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eBook: Outsourcing — India's Burgeoning Biologics CDMO Marketplace

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Economics
Navigating Choppy Waters: Three Resilient Marketing Tactics for Biotechnology
Companies amid Market Turmoil
Navigating Choppy Waters: Three Resilient Marketing Tactics for Biotechnology
Companies amid Market Turmoil

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Therapeutic Modalities

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Cell Therapies
Elevating the CGT Manufacturing Game: How Outsourcing Enables Success
Elevating the CGT Manufacturing Game: How Outsourcing Enables Success
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eBook: Allogeneic Cell Therapy — From Clinical Concept to Viable Product

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Emerging Therapeutics
A Milestone in Macrophage-Based Cancer Treatment: Leveraging Chimeric Antigen
Receptors To Address Solid Tumors
A Milestone in Macrophage-Based Cancer Treatment: Leveraging Chimeric Antigen
Receptors To Address Solid Tumors

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LATEST EBOOKS

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Facility Design/EngineeringeBook: Sustainable Facilities — Emerging Approaches
to Design and ConstructioneBook: Sustainable Facilities — Emerging Approaches to
Design and Construction



Cell TherapieseBook: Challenges of Commerical-Scale Autologous CAR-T Cell
ManufacturingeBook: Challenges of Commerical-Scale Autologous CAR-T Cell
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Special Reports


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Scaling Up mAb Production with a Platform Medium and Feed SystemScaling Up mAb
Production with a Platform Medium and Feed System

As the monoclonal-antibody (mAb) market continues to grow, it is becoming
increasingly important for pharmaceutical and biotech companies to accelerate
process development and establish a scalable manufacturing process capable of
achieving high titers and consistent product quality. Central to this is a cell
culture media and feed system that can provide the required nutrients for
optimal cell growth, viability, and function, as well as facilitate a seamless
transition from development to clinical and commercial manufacturing. However,
choosing an appropriate system can be a complex and time-consuming process,
often requiring the evaluation of multiple medium and feed options. Platform
systems, consisting of a medium and complementary feed developed for a specific
cell line and application, have emerged as a valuable option for developers to
help simplify selection and increase scale-up efficiency. To meet the need for
high-performance platform mAb manufacturing solutions, Thermo Fisher Scientific
has dev...

Sponsored Content
From Pipettes to Infusion Pumps: Volume Accuracy in Regulated Industries and Its
Critical ImpactFrom Pipettes to Infusion Pumps: Volume Accuracy in Regulated
Industries and Its Critical Impact

Precision in volume delivery is critically important for both the
biopharmaceutical and medical device industries. This special report discusses
how accurate volume measurement affects patient safety, product quality, and
regulatory compliance. Sartorius emphasizes the roles that infusion pumps,
laboratory pipettes, and quality control (QC) measures play in ensuring reliable
and reproducible results. Register or Login and hit Download Now to get the full
Special Report.

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Ask the Expert Webcasts


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Enhancing Efficiency and Quality in Biopharmaceutical Manufacturing: The
Strategic Value of Pre-Packed Chromatography Columns in Lean
ManufacturingEnhancing Efficiency and Quality in Biopharmaceutical
Manufacturing: The Strategic Value of Pre-Packed Chromatography Columns in Lean
Manufacturing

This webcast features: Adam Nelson, Chromatography Product Manager, Repligen.
Pre-packed chromatography columns have emerged as a valuable tool in process
development, clinical manufacturing, and commercial production, offering
significant advantages over self-packed columns. The adoption of pre-packed
columns aligns with lean manufacturing best practices, which emphasize the
reduction of non-value-adding activities. This study evaluates the benefits of
using pre-packed columns in biopharmaceutical production. Pre-packed columns are
pre-validated and ready-to-use, eliminating the time-consuming and
labor-intensive steps associated with self-packing. This results in substantial
time savings and improved operational efficiency. By reducing the risk of human
error delays during column packing, pre-packed columns enhance process
consistency and reliability, leading to improved product quality. Key takeaways:
In conclusion, pre-packed chromatography columns offer a strategic advantage in
biopharmaceutical m...

Sponsored Content
Decoding AAV Manufacturing: Navigating Critical Quality Attributes and their
AnalyticsDecoding AAV Manufacturing: Navigating Critical Quality Attributes and
their Analytics

This webcast features: Roland Pach, PhD, Global Analytical Expert, CMC, CGT, &
Alternative Formats, Roche. Gene therapy based therapeutics offer revolutionary
ways of treating and curing genetic disorders. CMC plays a crucial part, however
it is faced with complex manufacturing processes and the intrinsic complexity of
the genetic therapeutics themselves. In this webinar, learn about key
pre-quality attributes in AAV manufacturing and the cognate landscape of
technologies analyzing them. There is a high need for more sophisticated methods
for improving and deepening the understanding of the process and product. Key
Takeaways: Register or Login and hit Watch on Demand to view the recorded
webcast now. 

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Process Control) for CHO Fed-Batch Application
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Process Control) for CHO Fed-Batch Application
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Process Control) for CHO Fed-Batch Application


High Productivity and Process Economy in GxP Applications with the Octet™
Platform
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Platform
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List of IAB Vendors‎

LINK DIFFERENT DEVICES 331 PARTNERS CAN USE THIS FEATURE

Always Active

In support of the purposes explained in this notice, your device might be
considered as likely linked to other devices that belong to you or your
household (for instance because you are logged in to the same service on both
your phone and your computer, or because you may use the same Internet
connection on both devices).

List of IAB Vendors‎

IDENTIFY DEVICES BASED ON INFORMATION TRANSMITTED AUTOMATICALLY 502 PARTNERS CAN
USE THIS FEATURE

Always Active

Your device might be distinguished from other devices based on information it
automatically sends when accessing the Internet (for instance, the IP address of
your Internet connection or the type of browser you are using) in support of the
purposes exposed in this notice.

List of IAB Vendors‎
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