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WELCOME TO UALCAN

YES! YOU ALL CAN

The University of ALabama at Birmingham CANcer data analysis Portal

--------------------------------------------------------------------------------

UALCAN is a comprehensive, user-friendly, and interactive web resource for
analyzing cancer OMICS data. It is built on PERL-CGI with high quality graphics
using javascript and CSS. UALCAN is designed to, a) provide easy access to
publicly available cancer OMICS data (TCGA, MET500, CPTAC and CBTTC), b) allow
users to identify biomarkers or to perform in silico validation of potential
genes of interest, c) provide graphs and plots depicting expression profile and
patient survival information for protein-coding, miRNA-coding and lincRNA-coding
genes, d) evaluate epigenetic regulation of gene expression by promoter
methylation, e) perform pan-cancer gene expression analysis, f) Provide
additional information about the selected genes/targets by linking to GeneCards,
Pubmed, TargetScan, The human protein atlas, DRUGBANK, Open Targets and the
GTEx. These resources allow researchers to gather valuable information and data
about the genes/targets of interest, g) provide clinical proteomic consortium
data analysis including total/phospho-proteins and h) provide pediatric brain
tumor gene expression and protein expression analysis.
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Please cite:

1) Chandrashekar DS, Karthikeyan SK, Korla PK, Patel H, Shovon AR, Athar M,
Netto GJ, Qin ZS, Kumar S, Manne U, Creighton CJ, Varambally S. UALCAN: An
update to the integrated cancer data analysis platform. Neoplasia. 2022
Mar;25:18-27. doi: 10.1016/j.neo.2022.01.001  [PMID: 35078134]


2) Chandrashekar DS, Bashel B, Balasubramanya SAH, Creighton CJ, Rodriguez IP,
Chakravarthi BVSK and Varambally S. UALCAN: A portal for facilitating tumor
subgroup gene expression and survival analyses. Neoplasia. 2017
Aug;19(8):649-658. doi: 10.1016/j.neo.2017.05.002 [PMID:28732212]


Updated slides from a presentation about UALCAN cancer database at Dana-Farber
Cancer Institute  





  UPDATES

09/26/2024

 1. MammOnc-DB, an integrative breast cancer proteogenomic data analysis
    platform with over 20,000 samples including single cell sequencing data is
    now online: http://resource.path.uab.edu/MammOnc-Home.html
    Associated preprint is at:
    https://www.researchsquare.com/article/rs-4926362/v1



08/29/2024

 1. UALCAN has been now visited over 1.5 Million times by cancer researchers
    from over 100 countries and cited over 6000 times

11/10/2023

 1. UALCAN Mobile, a free companion tool /app for UALCAN is now available in App
    store and Google Play store. This app will make UALCAN/TCGA cancer gene
    expression data readily accessible for researchers through phones and
    tablets and make target discovery at the fingertips.
    Download UALCAN Mobile app at:
    https://play.google.com/store/apps/details?id=edu.uab.path.ualcan
    https://apps.apple.com/us/app/ualcan-mobile/id6450547634

09/14/2023

 1. Our new publication in Nature communications "Chen F, Zhang Y, Chandrashekar
    DS, Varambally S, Creighton CJ. Global impact of somatic structural
    variation on the cancer proteome. Nature Communications, 2023 Sept., 13
    ;14(1):5637. doi: 10.1038/s41467-023-41374-8."

08/16/2022

 1. UALCAN now aids cancer researchers in obtaining list of potential prognostic
    markers

05/13/2022

 1. Zhang, Y., Chen, F., Chandrashekar, D.S., Varambally, S., Creighton, C.J.
    Proteogenomic characterization of 2002 human cancers reveals pan-cancer
    molecular subtypes and associated pathways. Nat Commun 13, 2669 (2022) doi:
    10.1038/s41467-022-30342-3 [PMID: 35562349]

12/13/2021

 1. UALCAN now allows gene expression analysis using data from The Children
    Brain Tumor Tissue Consortium(CBTTC). Chen, F., Chandrashekar, D.S.,
    Scheurer, M.E., Varambally, S., Creighton, C.J. Global molecular alterations
    involving recurrence or progression of pediatric brain tumors. Neoplasia 24,
    22-23 (2022) doi:10.1016/j.neo.2021.11.014 [PMID: 34864569]

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Oct. 08th - Nov. 08th





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