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ISSN: 1838-7640Theranostics
 
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Nanotheranostics 2024; 8(3): 312-329. [Abstract] [Full text] [PDF]

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Nanotheranostics 2024; 8(3): 298-311. [Abstract] [Full text] [PDF]

Nanotheranostics

International Journal of Biological Sciences

International Journal of Medical Sciences

Journal of Cancer

Global reach, higher impact

Theranostics publishes innovative research articles reflecting the fields of in
vitro diagnostics and prognostics, in vivo molecular imaging, molecular
therapeutics, image-guided therapy, biosensors, system biology and translational
medicine, personalized medicine and a broad spectrum of biomedical research that
can be applied to future theranostic applications.

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Research Paper
Intravital imaging of splenic classical monocytes modifying the hepatic CX3CR1+
cells motility to exacerbate liver fibrosis via spleen-liver axis
Chenlu Han, Yujie Zhai, Yuke Wang, Xuwen Peng, Xian Zhang, Bolei Dai, Yuehong
Leng, Zhihong Zhang, Shuhong Qi
Theranostics 2024; 14(5): 2210-2231. doi:10.7150/thno.87791
Abstract Full text PDF

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Research Paper
G protein subunit alpha i2's pivotal role in angiogenesis
Chao-wen Bai, Lu Lu, Jia-nan Zhang, Chengyu Zhou, Yi-chao Ni, Ke-ran Li, Jin
Yao, Xiao-zhong Zhou, Chang-gong Lan, Cong Cao
Theranostics 2024; 14(5): 2190-2209. doi:10.7150/thno.92909
Abstract Full text PDF

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Research Paper
Immunotherapeutic IL-6R and targeting the MCT-1/IL-6/CXCL7/PD-L1 circuit prevent
relapse and metastasis of triple-negative breast cancer
Aushia Tanzih Al Haq, Pao-Pao Yang, Christopher Jin, Jou-Ho Shih, Li-Mei Chen,
Hong-Yu Tseng, Yen-An Chen, Yueh-Shan Weng, Lu-Hai Wang, Michael P. Snyder,
Hsin-Ling Hsu
Theranostics 2024; 14(5): 2167-2189. doi:10.7150/thno.92922
Abstract Full text PDF

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Research Paper
FSH induces EMT in ovarian cancer via ALKBH5-regulated Snail m6A demethylation
Xingyan Xu, Xuefen Zhuang, Haowei Yu, Ping Li, Xiaosa Li, Huiping Lin, Jian-peng
Teoh, Yiwen Chen, Yuanlan Yang, Yang Cheng, Weiyu Chen, Xiaodong Fu
Theranostics 2024; 14(5): 2151-2166. doi:10.7150/thno.94161
Abstract Full text PDF

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Research Paper
An advanced comprehensive muti-cell-type-specific model for predicting anti-PD-1
therapeutic effect in melanoma
Wei Sun, Yu Zhu, Zijian Zou, Lu Wang, Jingqin Zhong, Kangjie Shen, Xinyi Lin,
Zixu Gao, Wanlin Liu, Yinlam Li, Yu Xu, Ming Ren, Tu Hu, Chuanyuan Wei, Jianying
Gu, Yong Chen
Theranostics 2024; 14(5): 2127-2150. doi:10.7150/thno.91626
Abstract Full text PDF

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Review
Engineered exosomes and composite biomaterials for tissue regeneration
Weikang Hu, Wang Wang, Zesheng Chen, Yun Chen, Zijian Wang
Theranostics 2024; 14(5): 2099-2126. doi:10.7150/thno.93088
Abstract Full text PDF

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Review
Unleashing the potential of adipose organoids: A revolutionary approach to
combat obesity-related metabolic diseases
Xingran Liu, Jing Yang, Yuxin Yan, Qingfeng Li, Ru-Lin Huang
Theranostics 2024; 14(5): 2075-2098. doi:10.7150/thno.93919
Abstract Full text PDF

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Research Paper
NPC1 is required for postnatal islet β cell differentiation by maintaining
mitochondria turnover
Bei Liu, Duanyi Hua, Linyan Shen, Tingting Li, Zheying Tao, Chenyang Fu,
Zhongzheng Tang, Jie Yang, Li Zhang, Aifang Nie, Yiran Jiang, Jiqiu Wang, Yang
Li, Yanyun Gu, Guang Ning
Theranostics 2024; 14(5): 2058-2074. doi:10.7150/thno.90946
Abstract Full text PDF

More ...

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD
Editor-in-chief profile

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 * Theranostics is indexed by Science Citation Index (SCI) and MEDLINE. (Full
   index information)
 * Full texts of articles in PubMed Central and Europe PMC. Abstracts in PubMed.

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Special Issue: Osteoarthritis Theranostics. Guest Editors: Dr. WEN, CHUNYI, Dr.
Magali Cucchiarini.

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CFP: Special issue on mRNA-based vaccine and therapy. Guest Editors: Guocan Yu
(Tsinghua University, China), Qiaobing Xu (Tufts University, USA), Wei Tao
(Harvard Medical School, USA)

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Background: The therapeutic benefits of targeting follicle-stimulating hormone
(FSH) receptor in treatment of ovarian cancer are significant, whereas the role
of FSH in ovarian cancer progresses and the underlying mechanism remains to be
developed. Methods: Tissue microarray of human ovarian cancer, tumor xenograft
mouse model, and in vitro cell culture were used to investigate the role of FSH
in ovarian carcinogenesis. siRNA, lentivirus and inhibitors were used to trigger
the inactivation of genes, and plasmids were used to increase transcription of
genes. Specifically, pathological characteristic....

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Rationale: NPC1 is a protein localized on the lysosome membrane regulating
intracellular cholesterol transportation and maintaining normal lysosome
function. GWAS studies have found that NPC1 variants in T2D was a pancreatic
islet expression quantitative trait locus, suggesting a potential role of NPC1
in T2D islet pathophysiology. Methods: Two-week-old Npc1-/- mice and wild type
littermates were employed to examine pancreatic β cell morphology and functional
changes induced by loss of Npc1. Single cell RNA sequencing was conducted on
primary islets. Npc1-/- Min6 cell line was generated using....

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Nanotheranostics is indexed in MEDLINE and PubMed Central ...

Research Paper
Biogenic Zinc Oxide Nanoparticles synthesized from Tinospora Cordifolia induce
oxidative stress, mitochondrial damage and apoptosis in Colorectal Cancer
Hadgu Mendefro Berehu, Srinivas Patnaik
Nanotheranostics 2024; 8(3): 312-329. doi:10.7150/ntno.84995
[Abstract] [Full text] [PDF]



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