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OUR MISSION IS TO PROVIDE THE BEST THROMBECTOMY SYSTEM TO HEALTH CARE
PROFESSIONALS.





NEXT GENERATION OF CATHETERS

Anaconda Biomed S.L. is a Barcelona based medical device start-up co-founded
by Dr. Marc Ribo and Dr. Ofir Arad. The company is developing the next
generation of catheters to perform safely and efficiently mechanical
thrombectomies.

Stroke is the first cause of permanent disability in the world. The burden for
the national health systems can be quantified in billions of dollars.



STENTRIEVER TECHNIQUE


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ASPIRATION TECHNIQUE

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ANA - ADVANCED NEUROVASCULAR ACCESS -

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https://anaconda.bio/wp-content/uploads/2021/04/ancd-technology.mp4

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COMPARATIVE VIDEO

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FEATURES

Intended Use: The ANA – Advanced Neurovascular Access – is intended to restore
blood flow in patients experiencing acute ischemic stroke due to a large vessel
neurovascular occlusion.



The ANA is designed for its use in the anterior and posterior neurovascular
vessels, such as the Internal Carotid Artery (ICA), the M1 and M2 segments of
the middle cerebral artery, the basilar, the posterior cerebral and the
vertebral arteries.

Description: The ANA is comprised of two coaxial catheters (Delivery catheter
and Funnel catheter) made from variable stiffness sections to be used in
conjunction with a Stent Retriever. The funnel catheter is comprised by a
radiopaque Nitinol braid covered with a Silicone coating to provide local flow
restriction. The delivery catheter has a hydrophilic coating to reduce friction
during use and a radiopaque marker on the distal end. Both catheters have a Luer
hub on the proximal end. The device is supplied pre-loaded in an insertion tool.

BENEFITS


A.- DISTAL FLOW RESTRICTION

(Versus a traditional Balloon Guiding Catheter)

1.- The Clot is dragged down for a shorter distance reducing the risk of rolling
out and fragmentation.
2.- Aspiraton is greatly improve as colateral flow is almost nil.
3.- Less territory is exposed to ischemia.


B.- STRONGEST SUCTION FORCE

1.- Suction (removal/retention force applied over the clot) is a matter of force
not of flow

Suction Force vs Flow – Video

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https://anaconda.bio/wp-content/uploads/2021/10/succion-1.mp4

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Suction Force vs Flow – Published Paper


2- Once vacuum is achieved (from 5s on)
3- Depends on radius at 2nd power
4- The bigger the distal end of the catheter, the stronger the force applied
over the Clot.


C.- SECURE RETRIEVAL

1.- The nitinol braided funnel will adjust to the artery diameter up to 5mm
limiting “shaving” and fragmentation.
2.- The combination of aspiration and stent retrievers is currently the most
reliable technic.
3.- Its covered structure will protect it from the flow further reducing
potential fragmentation.


D.- SAFE EXITS

1.- The combination of the covered funnel and the stent retriever will avoid any
risk of “roll-out”.
2.- The same combination will avoid distal emboli when entering the Guiding
Catheter.
3.- In addition, aspiration is applied during the all extraction path.


E.- RESULTS

A.- IN VITRO STUDIES:
Paper released in JNIS, June 2019.  ANCD thrombectomy device: in vitro
evaluation



Sanchez S, et al. ANCD thrombectomy device: in vitro evaluation. J Neurointerv
Surg. 2020 Jan; 12(1):77-81.

B.- IN VIVO STUDIES:
Paper released in JNIS, January 2020. ANCD thrombectomy device: in vivo
evaluation



Sanchez S, et al. Preclinical evaluation of the ANCD thrombectomy device: safety
and efficacy in a swine clot model. J Neurointerv Surg. 2020 Oct;
12(10):1008-1013

C.- IN HUMAN STUDIES:
Paper released at Journal of Neuroradiology, January 2021. Initial clinical
experience with the ANA thrombectomy device



``DEVICE UNDER REGULATORY CLEARANCE - NOT AVAILABLE FOR COMMERCIAL SALE``

EVERY TWO SECONDS SOMEONE IN THE WORLD EXPERIENCES A STROKE. GET INVOLVED AND
CHANGE THEIR LIVES.



INVESTORS



WITH THE SUPPORT OF




MEMBERS OF




Anaconda Biomed © 2022
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