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COVID-19 VACCINE SIDE EFFECT TRACKER

COVID-19: Updates
by Emma Yasinskilast updated: September 28, 2021

MOST RECENT UPDATES:

Click the dates to jump to more details.

* September 28: The CDC released data showing that the side effects of a third
shot of Pfizer’s vaccine are similar to those of the second shot.
* September 2: Researchers in Israel reviewed medical records of patients who
had experienced Guillan-Barre Syndrome (GBS) prior to receiving Pfizer’s
COVID-19 shot. Of the 579 patients, five were transferred to the hospital for
neurological symptoms such as tremors or prickling sensations. Only one
patient required medical care for relapse of GBS.
* August 22: Researchers published two case studies of patients experiencing
neurological effects such as losing balance and non-epileptic convulsions
after the Pfizer and AstraZeneca vaccines. They emphasize that functional
neurological disorders are treatable.
* August 19: The FDA and CDC are investigating the possibility that Moderna’s
vaccine could be up to 2.5 times more likely to be associated with
myocarditis (heart inflammation), especially for males under 30 years old. If
true, the effect would still be exceedingly rare and scientists say the
benefits still greatly outweigh the harms of vaccination. Most patients
recover on their own with minimal intervention.
* August 18: The FDA and CDC authorized third shots for patients with specific
conditions that compromise their immune systems. The Biden administration has
also pushed for booster shots to be made available to everyone, eight months
after their second dose, in response to waning antibody levels and a rise in
breakthrough infections. People who took Pfizer, Moderna or J&J’s vaccines
are still highly protected against hospitalization and death. This plan is
not yet authorized. The agencies are also waiting for data to provide
guidelines specific to J&J vaccine recipients in the coming weeks.
* July 12: The FDA is attaching a warning to the Johnson & Johnson vaccine
about a slightly elevated risk of developing Guillain-Barre syndrome within
three weeks of receiving the vaccine. The benefits still out weight the risks
of vaccination, it says.
* June 23: About 1.9% of healthcare employees who received an mRNA vaccination
had a skin reaction such as itching or a rash after the first dose. Most
(83%) who reported a skin reaction after the first dose, did not experience
it again after the second dose, according to a study today in JAMA
Dermatology. Another 2.3% experienced a skin reaction after only the second
dose.

To help you sort through the news on the COVID-19 vaccine’s progress, MedShadow
has created the MedShadow Vaccine Tracker, the only tracker focused on the side
effects and adverse events associated with proposed COVID-19 vaccinations.

Rather than injecting patients with a weakened virus or proteins from the
pathogen that our immune systems can recognize, which is what’s typically done
when we get a flu vaccine, the new vaccines from Moderna and Pfizer — the two
that made it to the market first in the U.S. — contain mRNA (messenger RNA),
which is a genetic template that instructs our cells to build the viral proteins
that our immune systems can then recognize. Its main perk is that allowing our
bodies to produce the proteins (rather than growing them in a lab like
traditional vaccines) slashes production time. For nearly 20 years, researchers
have been interested in using mRNA in vaccines; and some were even tested in
early clinical trials for rabies, influenza and Zika. However, the vaccines for
COVID-19 will be the first mRNA vaccines ever authorized by the FDA.

Some risks and minor side effects, such as a sore arm where the vaccine is
injected or a light skin rash, are clearly worth the benefit of being protected
against a disease. Where to draw the line at what is or is not acceptable is a
personal decision. That’s where the MedShadow Vaccine Tracker can help.

On the tracker, we will be publishing up-to-date Phase 3 results information
about the risks of each vaccination. Phase 3 tests the vaccine for safety and
efficacy in large groups of people (tens of thousands) and is the last stage
before the FDA considers approval for use in the population at large. We
continue following verified reports as the vaccines are offered to the general
public. It is important to note that reports of events occurring after
vaccination are not inherently linked to it. As countries begin to vaccinate
hundreds of millions of people, some would inevitably be diagnosed with
illnesses or pass away each day with or without the injections.

Jump to:

Moderna | Pfizer | CanSinBio (China) | Gameleya (Russia) | Johnson & Johnson

MODERNA

Moderna started Phase III clinical trials for its vaccine candidate in July. In
earlier trials, nearly half of patients experienced common adverse effects like
injection site pain, rash, headaches, muscle soreness, nausea and fevers after
the second injection. These effects generally subsided within two days. CNBC
spoke to a few individuals, some participating in Moderna’s trial and some in
Pfizer’s trial who said much the same thing: the side effects were intense and
included a high fever, body aches, bad headaches and exhaustion, but were worth
it for protection from Covid-19.

In the FDA report published in December, the most common side effects were pain
at injection site (91.6% of patients), fatigue (68.5%), headache (63.0%), muscle
pain (59.6%), joint pain (44.8%), and chills (43.4%). Three patients experienced
Bell’s Palsy, a sudden, and usually temporary, weakening or paralysis of the
facial muscles.

The CDC reports that 11% of patients experienced swollen lymph nodes after the
first shot. That raised to 16% after the second shot.

A few patients with facial fillers experienced swelling after receiving the
vaccine. They were treated with antihistamines and steroids.

January 18: In California, officials halted the use of one particular batch of
Moderna vaccines (lot 41L20A) after a small cluster (fewer than 10) of patients
at one particular site experienced allergic reactions that required medical
attention.

February 1: A study posted on Feb 1 showed that patients who received the
vaccine after having been previously infected with COVID-19 showed greater
immune response to the first shot and more intense side effects that are
associated with strong immune responses like fever and muscle aches. The study
included patients who received either the Moderna or Pfizer vaccine. Some
scientists believe these patients may only need a single shot to provide
sufficient immunity, but more research is needed.

February 12: Out of the first 7.5 million doses administered from Dec 14- Jan
18, 19 cases of anaphylaxis were reported to VAERS after the Moderna vaccine. No
patients have died from anaphylaxis. Patients are now being monitored for 15-30
minutes after receiving the vaccine to watch for signs of anaphylaxis. The CDC
suggests that anyone who has an immediate allergic reaction to a single dose of
an mRNA vaccine (Moderna or Pfizer) should not get the second dose. If your
reaction was not immediate, you may be referred to an allergy specialist. The
vaccines do not contain polysorbate, but do have a related ingredient,
polyethylene glycol (PEG). If you have an allergy to either of these chemicals,
you should not get the vaccines.

Many patients are reporting injection site reactions that show up shortly after
the injection or up to a week later. These reactions — which are characterized
by swelling, redness, itching, rashes, heat and pain — are expected to last a
day to a week. Physicians emphasize that while these effects can be scary, they
are not dangerous and should not prevent someone from getting the second shot.
So far, doctors do not report seeing these reactions after the second shot,
however so few have been given so far that scientists are not sure how common it
will be on round two.

March 3: Allergy researchers at Mass General Hospital created a registry for
healthcare professionals to report immediate and delayed reactions to COVID-19
vaccinations. On March 3, the researchers published a letter in the New England
Journal of Medicine describing a series of 12 delayed injection site reactions
including swelling and rashes. The researchers wrote that one patient received
antibiotics although they were not necessary. Several others were treated with
steroids or anti inflammatories. The letter included some photos and said that
the reactions cleared up within a median of six days. Patients were encouraged
to receive their second dose. Half of them did not experience the reaction the
second time. A quarter did, but to a lesser degree.

March 8: Researchers from Mass General Brigham published a Research Letter in
JAMA analyzing allergic reactions in employees who received their shots there.
Out of 52,805 participants, 2.1% experienced some kind of allergic reaction,
including hives, itching, rash, swelling or respiratory symptoms within the
first three days after vaccination. Allergies were slightly more common with the
Moderna vaccine than the Pfizer vaccine (2.2% compared to 1.95%). Sixteen
experienced anaphylaxis.

Moderna has announced that it will begin testing its vaccine in children and
adolescents, who they believe may have stronger immune responses, leading to
more intense side effects.

April 20: Researchers have received over 25,000 responses to an online survey
regarding menstrual changes after receiving any COVID-19 vaccine. The survey is
ongoing as researchers hope to gain a better understanding of future directions
of research. An op-ed in the New York Times explains how the vaccines could
potentially interact with menstrual cycles, and why we really don’t know yet.

April 22: The CDC published an analysis of data from the first few months of
voluntary V-safe surveys that suggested that the Moderna and Pfizer vaccines are
safe for pregnant women. Pregnant patients self-reported slightly fewer side
effects like fever, headache and chills than the general population, but more
said they experienced nausea and injection site pain. Rates of adverse pregnancy
outcomes such as pre-term birth were similar to rates seen before the pandemic.
While promising, officials noted that more studies will be required.

April 26: MedShadow asked doctors about some of the unusual symptoms we’re
hearing about in the comments: heart palpitations and visual disturbances. They
hadn’t had patients who reported long-term symptoms, but said that if the
symptoms occurred very quickly after vaccination, they could be related to
allergic reactions or presyncope.

April 27: Clinical trials of Moderna and Pfizer vaccines showed 7 cases of
Bell’s Palsy. An analysis published today in JAMA suggested the experience was
no more frequent after these vaccines than other vaccines. It is unclear whether
vaccines raise the risk of facial paralysis at all, but the authors write, “if
an association between facial paralysis and mRNA COVID-19 vaccines exists, the
risk is likely very low, as with other viral vaccines.”

May 5: Researchers published a detailed analysis of skin reactions after Moderna
and Pfizer vaccinations, including swelling and rashes. Most patients with first
dose reactions did not have reactions after their second dose. Larger reactions
on the arm spreading outward from the injection site were the most common
reactions among those who received the Moderna vaccine, followed by smaller
localized reactions and hives. Five patients (1.9%) experienced a zoster
(shingles) flare after the first dose but none after the second dose. About 1%
of patients experienced a flare of an existing skin condition after each dose.

May 20: An analysis published in JAMA suggests that hearing loss is NOT a side
effect of the Pfizer or Moderna vaccines.

June 10: The CDC says that as of May 31, VAERS had received 475 reports of
myocarditis or pericarditis among people 30 years of age and younger who
received a COVID-19 vaccine. Upon follow-up, the CDC and FDA confirmed 226 of
the reports. They emphasize that more than 18 million people between ages 12-24
have received at least one dose of COVID-19 vaccine in the United States. A CDC
Fact Sheet on the effect is available here.

June 23: About 1.9% of healthcare employees who received an mRNA vaccination had
a skin reaction such as itching or a rash after the first dose. Most (83%) who
reported a skin reaction after the first dose, did not experience it again after
the second dose, according to a study today in JAMA Dermatology. Another 2.3%
experienced a skin reaction after only the second dose.

August 18: The FDA and CDC authorized third shots for patients with specific
conditions that compromise their immune systems. The Biden administration has
also pushed for booster shots to be made available to everyone, eight months
after their second dose, in response to waning antibody levels and a rise in
breakthrough infections. People who took Pfizer, Moderna or J&J’s vaccines are
still highly protected against hospitalization and death. This plan is not yet
authorized. The agencies are also waiting for data to provide guidelines
specific to J&J vaccine recipients in the coming weeks. Around a million people
have gotten third shots so far in the US and abroad. The FDA hasn’t reviewed all
of the data yet, but no new safety concerns have emerged thus far. See answers
to frequently asked questions regarding the booster shots here.

August 19: The FDA and CDC are investigating the possibility that Moderna’s
vaccine could be up to 2.5 times more likely to be associated with myocarditis
(heart inflammation), especially for males under 30 years old. If true, the
effect would still be exceedingly rare and scientists say the benefits still
greatly outweigh the harms of vaccination. Most patients recover on their own
with minimal intervention.

PFIZER

Pfizer began Phase III clinical trial for its vaccine candidate in July. In
earlier trials, some patients experienced common adverse effects like injection
site pain, rash, headaches, muscle soreness, nausea and fevers. These effects
generally subsided within two days. CNBC spoke to a few individuals, some
participating in Pfizer’s trial and others in Moderna’s trial who said much the
same thing: the side effects were intense and included a high fever body aches,
bad headaches and exhaustion in addition to the more common side effects, but
were worth it for protection from Covid-19.

Some patients described the side effects as being similar to a bad hangover. A
nurse who participated in the clinical trial reported feeling minimal effects
after the first dose, but a fever that reached more than 104 degrees Fahrenheit
after the second injection, along with chills, headache, and intense injection
site pain. According to researchers, her experience of having all symptoms
together was rare, though many patients had one or two of these side effects.
“Clinicians will need to be prepared to discuss with patients why they should
trust the vaccine and that its adverse effects could look a lot like COVID-19,”
the nurse wrote on Dec 7.

The FDA report published in December said the most common reactions were
injection site reactions (84.1%), fatigue (62.9%), headache (55.1%), muscle pain
(38.3%), chills (31.9%), joint pain (23.6%), fever (14.2%). Swollen lymph nodes
occurred in 0.3% of patients. The FDA reported that four patients who received
the vaccine experienced Bell’s Palsy.

January 12: A doctor in Florida died 16 days after receiving the vaccine from a
rare blood disorder, acute immune thrombocytopenia. Both Pfizer and the CDC are
investigating, though the company has released a statement that so far, they
haven’t seen any signs in the clinical trials or data collected from early
vaccinations that the death could be related to the vaccine. The blood disorder
immune thrombocytopenia, has also been seen as a rare complication of COVID-19
itself, in both symptomatic and asymptomatic patients.

January 19: Twenty-three elderly patients in Norway died after receiving
Pfizer’s vaccine. Officials are investigating whether or not the deaths are
vaccine-related. Anthony Fauci, MD, director of the National Institute of
Allergy and Infectious Diseases, suggests that while the deaths may be
coincidental given the fragile population, it’s possible that side effects of
the vaccines, like fevers, may have strained the frail patients’ bodies and
contributed to their deaths. Norway has vaccinated about 45,000 people so far,
most of whom live in nursing homes.

February 12: Out of the first 9.9 million doses administered from Dec 14- Jan
18, 47 cases of anaphylaxis were reported to VAERS after the Pfizer vaccine.
Patients are now being monitored for 15-30 minutes after receiving the vaccine
to watch for signs of anaphylaxis. The CDC suggests that anyone who has an
immediate allergic reaction to a single dose of an mRNA vaccine (Moderna or
Pfizer) should not get the second dose. If your reaction was not immediate, you
may be referred to an allergy specialist. The vaccines do not contain
polysorbate, but do have a related ingredient, polyethylene glycol (PEG). If you
have an allergy to either of these chemicals, you should not get the vaccines.

March 30: Researchers publish a case study of a single patient in which they
suspect the Pfizer vaccine may have caused a rheumatoid arthritis flare. The
flare was treated, and the patient is in remission. The researchers and RA
advocacy groups still advise patients to get the vaccine as the benefits
outweigh the risks of a flare up.

May 5: Researchers published a detailed analysis of skin reactions after Moderna
and Pfizer vaccinations, including swelling and rashes. Nearly a quarter of
patients had smaller local reactions after each of the two shots. Hives were the
most common skin reaction (26% after the first shot, 18% after the second,)
among patients who received the Pfizer vaccine. Several also experienced flares
of existing skin conditions.

May 10: Pfizer’s vaccine received Emergency Use Authorization for 12 to
15-year-olds. The company reported that common adverse effects like chills and
fever were more common in this age group than adults. Adverse reactions in
adolescents 12 through 15 years of age included pain at the injection site
(90.5%), fatigue (77.5%), headache (75.5%), chills (49.2%), muscle pain (42.2%),
fever (24.3%), joint pain (20.2%), injection site swelling (9.2%), injection
site redness (8.6%), lymphadenopathy (0.8%), and nausea (0.4%). These effects
generally subsided within 1-2 days. While data on syncope (fainting) was not
included, the announcement mentioned that fainting after vaccination is more
common in teens than adults, and that safety measures should be in place to
reduce this risk.

May 20: An analysis published in JAMA suggests that hearing loss is NOT a side
effect of the Pfizer or Moderna vaccines.

May 23: The CDC is investigating reports of myocarditis in a small number of
vaccinated teens. Myocarditis, or inflammation of the heart, has multiple causes
but a viral infection is the most common trigger. In 2019, one million people
were diagnosed with myocarditis, most of them under 40 years old. It’s not yet
clear if these events were related to the vaccine.

June 9: A study in Nature Medicine suggests that there may be a very slightly
elevated risk of blood disorders after receipt of the AstraZeneca vaccine, but
NOT Pfizer’s. The study was based on an analysis of medical records in Scotland.
Researchers say the vaccine’s benefits still outweigh the risks and that their
results should not alter policy. The rates are similar to those seen with other
common vaccines.

August 22: Researchers published two case studies of patients experiencing
neurological effects such as losing balance and non-epileptic convulsions after
the Pfizer and AstraZeneca vaccines. They emphasize that functional neurological
disorders are treatable.

September 2: Researchers in Israel reviewed medical records of patients who had
experienced Guillan-Barre Syndrome (GBS) prior to receiving Pfizer’s COVID-19
shot. Of the 579 patients, five were transferred to the hospital for
neurological symptoms such as tremors or prickling sensations. Only one patient
required medical care for relapse of GBS.

September 28: V-Safe data from 306 people who received their third shots showed
that nearly identical numbers of patients reported side effects to the second
and third shots. 79.4% and 74.1% reported local or systemic reactions,
respectively, after the third dose compared to 77.6% and 76.5% who reported
local or systemic reactions after the second dose, respectively.

CANSINBIO (CHINA)

China granted the CanSinBio vaccine emergency approval prior to beginning a
Phase III trial in August. In the Phase II trial, nearly three-quarters of
patients reported at least one common mild adverse events including injection
site pain, rash, headaches, muscle soreness, and fevers. Five people also
reported vomiting.

GAMALEYA RESEARCH INSTITUTE (RUSSIA)

Gamaleya Research Institute launched Phase III trials in August. But before they
got started, President Putin announced that the vaccine was approved early,
however, the Phase III trials are expected to continue. In the earlier trials,
almost all of the patients experienced low-grade fevers. A small number of
patients reported heart palpitations. Otherwise, reported side effects were
similar to other vaccines and included injection site pain, rash, headaches, and
muscle soreness.

Feb 2: The group reported efficacy data along with some data on side effects in
The Lancet. The most common adverse events were flu-like illness (15.2% of those
vaccinated) and local reactions (5.4% of those vaccinated).

The report also states that there were six grade 3 adverse events which were not
associated with the vaccination: acute sinusitis, an exacerbation of
urolithiasis along with renal colic and deep vein thrombosis (both associated
with pre-existing comorbidities) and extremity abscess (due to physical injury
and subsequent infection of the wound surface of the soft tissues of the
finger).

JOHNSON & JOHNSON

Johnson & Johnson started a Phase III trial for its vaccine candidate in
September 2020, but paused it on October 12 due to an unexplained illness and
remains on hold. The company announced it would restart the trial on October 26.
Pauses are common during clinical trials to evaluate specific adverse events,
but the company has not shared details about the illness experienced by one of
the trial volunteers. In earlier trials, about 70% of patients experienced at
least one mild adverse effect similar to those seen with other vaccines,
including injection site pain, rash, headaches, muscle soreness, and fevers.

On Feb 24, Johnson & Johnson shared data from its Phase III trials. The data
suggested that while the vaccine is slightly less protective overall (but more
protective against the 501Y.V2 variant that emerged from South Africa,) than the
Moderna and Pfizer vaccines, it produced fewer side effects.

The report says the most common reactions were injection site reactions (50.2%),
fatigue (38.2%), headache (38.9%), muscle pain (33.2%), nausea (14.2%) and fever
(9.0%). Reactions were more common in patients under 60 than over 60.

Injection site pain lasted a median of 2 days, but up to 7 days in 2.3% of
patients.

April 8: A vaccination site in Colorado paused operations after 11 patients
became nauseous and dizzy minutes after receiving the Johnson & Johnson vaccine.
Two patients were transmitted to the hospital, but the rest were deemed healthy
enough to return home. Officials said that those vaccinated at the same site
should not be concerned.

April 13: The U.S. is calling for a pause on distributing the Johnson & Johnson
vaccine while the FDA and CDC investigate blood clots that occurred in six
patients (out of 7 million who received the vaccine so far.) One patient died
and another was hospitalized. All the clots occurred in women under 50 within
two weeks of receiving the vaccine. The issue is similar to the one seen with
the AstraZeneca vaccine in Europe.

April 23: The U.S. is resuming use of the vaccine after finding only 15 total
cases of blood clots out of the 7 million vaccinated. Patients will be warned
about the risk at vaccination sites. Symptoms including headache, leg pain and
abdominal pain occur 6-14 days after vaccination. If you have these symptoms you
should seek emergency medical treatment. It is treatable with certain blood
thinners.

April 27: Doctors suggested that patients with a history of immune-mediated
thrombocytopenia, such as heparin-induced thrombocytopenia, should not get the
Johnson and Johnson vaccine (mRNA vaccines like Pfizer and Moderna are ok). If
you’re at an increased risk for other types of blood clots, (because you have
obesity or you smoke, for example) you do not have an elevated risk of blood
clots with the J&J vaccine.

April 30: Researchers published detailed data about 12 patients who experienced
blood clots in JAMA.

May 13: The CDC has identified more cases of the rare clotting disorder
associated with the J&J vaccine. The total is 28 cases. Three patients have died
and four are still hospitalized. It’s more common in women than in men, and the
benefits still outweigh the risks of vaccination, officials say. Nine million
doses of the vaccine have been delivered in the U.S.

May 26: A 37-year old woman in Belgium died from a blood clot thought to be
related to the Johnson and Johnson vaccine she received. The country has stopped
using the vaccine in patients under the age of 41.

July 12: The FDA is attaching a warning to the Johnson & Johnson vaccine about a
slightly elevated risk of developing Guillain-Barre syndrome, which can cause
paralysis, within three weeks of receiving the vaccine. About 100 cases have
been identified. Most patients recovered. One 57-year-old man died. The benefits
still out weight the risks of vaccination, it says.

August 22: The FDA and CDC authorized third shots for patients with specific
conditions that compromise their immune systems. The Biden administration has
also pushed for booster shots to be made available to everyone, eight months
after their second dose, in response to waning antibody levels and a rise in
breakthrough infections. People who took Pfizer, Moderna or J&J’s vaccines are
still highly protected against hospitalization and death. This plan is not yet
authorized. The agencies are also waiting for data to provide guidelines
specific to J&J vaccine recipients in the coming weeks. Around a million people
have gotten third shots so far in the US and abroad. The FDA hasn’t reviewed all
of the data yet, but no new safety concerns have emerged thus far. See answers
to frequently asked questions regarding the booster shots here.

ASTRAZENECA

On September 6, the company paused the trial to investigate a patient who
developed transverse myelitis – dangerous inflammation of the spinal cord.
Researchers determined that the incident was unrelated to the vaccine and
quickly restarted the trial in most countries, however it remained paused in the
US until October 26. On October 21, scientists reported a patient in the trial
had died, however, according to a local newspaper, the patient was in the
control arm of the trial, meaning they’d received a placebo instead of the
vaccine, so the trial is ongoing.

In earlier trials, many patients reported mild adverse effects similar to those
associated with the other vaccines including injection site pain, rash,
headaches, muscle soreness, and fevers. The team gave some of these patients
preventative acetaminophen to reduce pain and fever. Nearly half of patients
also experienced temporary neutropenia – a reduction in white blood cells that
can make a person more susceptible to infections.

The vaccine has been approved for use in the U.K., Argentina, India, E.U. and
Mexico.

March 11: Denmark has paused the use of the AstraZeneca vaccine while it
investigates whether it is responsible for blood clots — one fatal — in some
patients.

“It is important for us that the citizens are confident in the offer we give
them and trust that we can vouch for the quality of the vaccines we have in our
program. Therefore, we react promptly until we have investigated whether there
is a connection between the vaccine and the possible side effects ,” officials
wrote in a press release.

March 15: Several other countries (Iceland, Norway, Denmark, Ireland, the
Netherlands, Italy, France and Germany) have also paused use of the vaccine
while unusual clotting events are investigated. Meanwhile, Thailand, which
paused its use on Friday, March 12 restarted it on Sunday, March 14. On Sunday,
AstraZeneca released a statement that its own review revealed “no increased
risk” of clotting issues with the vaccine and that “So far across the EU and
UK, there have been 15 events of DVT [deep vein thrombosis] and 22 events of
pulmonary embolism reported among those given the vaccine, based on the number
of cases the Company has received as of 8 March. This is much lower than would
be expected to occur naturally in a general population of this size and is
similar across other licensed COVID-19 vaccines.”

March 18: The European Medicines Agency (EMA) issued a statement that the
benefits of the AstraZeneca vaccine outweigh the risks. The vaccine is not
associated with an overall risk of blood clots, though there may be a very small
increased risk of certain types of clots. The statement reads, “These are rare
cases – around 20 million people in the UK and EEA had received the vaccine as
of March 16 and EMA had reviewed only 7 cases of blood clots in multiple blood
vessels (disseminated intravascular coagulation, DIC) and 18 cases of CVST
[clots in the vessels that drain blood from the brain.] A causal link with the
vaccine is not proven, but is possible and deserves further analysis.” These
cases were more common in women under the age of 55. Germany, France, Italy,
Latvia, Bulgaria and Slovenia have all stated that they’d restart or continue to
offer the AstraZeneca vaccine in light of the news.

April 7: The EMA still says the benefits of the vaccines outweigh the risks.
However, the group has suggested that blood clots be listed as a possible,
albeit rare, side effect of the injection and that both patients and doctors be
aware of the signs which include: shortness of breath, chest pain, leg swelling,
persistent abdominal pain, neurological symptoms like blurry vision and blood
spots under the skin beyond the site of injection. If you have these symptoms,
seek medical assistance.

April 9: Out of 34 million recipients of the vaccine, 222 have reported blood
clots. They appear to be more likely in younger patients, but it’s otherwise
impossible to predict who will experience them. Some experts say they can be
treated with intravenous immune globulin, which is currently used to treat
immune disorders along with some types of blood thinners.

June 9: A study in Nature Medicine suggests that there may be a very slightly
elevated risk of blood disorders after receipt of the AstraZeneca vaccine, but
not Pfizer’s. The study was based on an analysis of medical records in Scotland.
Researchers say the vaccine’s benefits still outweigh the risks and that their
results should not alter policy. The rates are similar to those seen with other
common vaccines.

NOVAVAX (UNITED KINGDOM)

Novavax began Phase III clinical trials with its vaccine candidate in the United
Kingdom in September and is had planned to start a trial in the United States in
October. The trial was delayed due to manufacturing problems. The U.S. trial
started on December 28. During Phase I/II trials, patients reported adverse
events similar to those of other vaccine candidates, including injection site
pain, rash, headaches, muscle pain, fever, nausea and vomiting.

June 14: Novavax announced promising efficacy data in a press release. The
release suggested that the vaccine has similar side effects to others already
approved, but that they may be slightly milder. Complete data is not yet
available.

SINOPHARM (CHINA)

In July, Sinopharm launched Phase III trials of its two vaccine candidates in
the United Arab Emirates, Peru, Morocco, and Argentina, which are now approved
for limited use in healthcare workers in China and the UAE. In earlier trials of
one of the vaccines, made in collaboration with Wuhan Institute of Biological
Products, about 15% of the patients reported adverse events similar to those of
other vaccine candidates, including injection site pain, rash, headaches, muscle
pain, fever, nausea and vomiting. There is little data available about the
second vaccine, made in collaboration with the Beijing Institute of Biological
Products.

SINOVAC (CHINA)

Sinovac opened Phase III trials of its vaccine candidate, CoronaVac, in July. It
is already being used with emergency approval for high risk individuals in
China. The earlier trials showed that about a third of patients experienced
adverse effects similar to those in other vaccine candidates like injection site
pain, fever, and fatigue, but the study included few details about more specific
symptoms like nausea, headaches, and vomiting. On November 10, the trial was
halted in Brazil due to a participant’s death. However, researchers say the
death was not vaccine-related and the trial should continue. It has not been
halted in other countries.

MURDOCH CHILDREN’S RESEARCH INSTITUTE (ENGLAND)

The Murdoch Children’s Research Institute is running a Phase III trial
repurposing Bacillus Calmette-Guerin — a vaccine developed nearly a century ago
to prevent tuberculosis infections — to prevent Covid-19. Since the vaccine has
been around such a long time, there are many reports on its potential adverse
effects and the vaccine itself has been altered to minimize many of them.
Injection site reactions are common, and lymphadenitis, swelling of the lymph
nodes, is common.

BHARAT BIOTECH

Bharat Biotech announced it would begin Phase III trials in India on October 23.
In early trials demonstrated side effect profiles similar to those of the other
vaccines, including pain at the injection site, fatigue, headache, and fever.
The country announced emergency approval, though no Phase III data was included
in the announcement.

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Tatiana
8 days ago

Please watch this press conference. Ex famous football player and his wife are
helping those who need a voice in this. I will list the link here of the
televised press conference with Senator Johnson and also the organization you
can contact privately to voice your concerns:
https://youtu.be/6mxqC9SiRh8
https://www.c19vaxreactions.com
I hope this information is useful in gaining understanding and helping us all
along with this extremely complex situation.

Saba
12 days ago

I wanted to come back here and post a positive story about insomnia issues after
the vax. You can see my previous posts of desperation from back in March. 42 y/o
male, with no health issues prior to vax. Rather I was very athletic and best
shape ever. First and only Moderna on 03/19/21. Did not take the 2nd shot due to
the side effects. I had severe insomnia starting the next night. It is hard to
describe the hell I went through because of insomnia for almost over 5 months.
Nothing, even rx meds didn’t work, especially the first… Read more »

Jack
15 days ago

4 months in from first jab of Moderna and struggling with my chest and unable to
sleep at night. Any kind of physical activity triggers a chest pain as if I had
fragments of glass inside. At night, anxiety hits me and unable to get any sleep
and if I do I worry that I’ll even wake up the next day.

Dave
15 days ago

https://www.news-medical.net/news/20210930/Comparison-of-Pfizer-Moderna-JJ-AZ-vaccines-for-neutralization-titer-against-Delta-and-other-variants.aspx

“A one-dose Moderna vaccine had the highest antibody titers compared to all
three vaccines.”

This reflects the fact that Moderna has been reported to contain a “higher
amount of active ingredient in the Moderna vaccine — 100 micrograms, versus 30
micrograms in Pfizer”.

https://www.bloomberg.com/news/articles/2021-08-31/moderna-jab-spurs-double-pfizer-covid-antibody-levels-in-study

SO, if one must get the vaccine, Moderna would provide the best protection
regardless of what side effects vaccines create.

Dave
17 days ago

We found that 1095 patients (45.0%) reported at least 1 symptom, and the most
common symptoms were fatigue, sweating, chest tightness, anxiety, and myalgia.
Older age, female gender, and severe disease were associated with higher risks
of fatigue or more symptoms. In total, 161 patients (6.6%) had CAT total scores
of at least 10, for which the risk factors included severe disease during
hospital stay or coexisting cerebrovascular diseases.

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2784558

Would be interesting to see what percentage of the vaccinated but never infected
get long term side effects.

Dave
17 days ago

JAMA Network Open full text iconFULL TEXTcontents iconCONTENTSfigure iconFIGURES
/ TABLESattach iconSUPPLEMENTAL CONTENTreferences iconREFERENCESrelated
iconRELATEDcomments iconCOMMENTS Download PDF Comment Top of Article Key Points
Abstract Introduction Methods Results Discussion Conclusions Article Information
References Figure 1. Study Flowchart Study Flowchart Figure 2. Total and Item
CAT Scores in Patients at 1-Year Follow-up Total and Item CAT Scores in Patients
at 1-Year Follow-up ADL indicates activities of daily living; CAT, COPD
assessment test; COPD, chronic obstructive pulmonary disease. Table 1.
Characteristics of Enrolled Patients Characteristics of Enrolled Patients Table
2. Symptoms at 1-Year Follow-up According to Disease Severity Symptoms at 1-Year
Follow-up… Read more »

ConcernedVaxxer
25 days ago

5 days after getting the 1st dose of the Pfizer vaccine I developed swelling,
bruising, pain and redness in my breast. There is a large area of very dark
bruising, swollen lymph nodes that are raised and visible through the skin and
tenderness to the touch. The symptoms are only in my left breast which is the
same side I had the vaccine injection (left arm). It’s been almost two months
and I still have daily breast pain, bruising and minor swelling in the left
breast. My doctor gave me Prednisone and the symptoms went away while I was
taking… Read more »

David
1 month ago

Report your adverse reaction to the vaccine at the VAERS website:
https://vaers.hhs.gov/reportevent.html
I myself took the second dose of Moderna back on April 30. Four days later I
began to experience heart palpitations / skipped heart beats that lasted for
months. My primary care physician and a different cardiologist told me they
didn’t think the vaccine was the direct cause (yeah, right). Anyway, I got
myself on magnesium citrate and the palpitations have thankfully gone away.

Robert
1 month ago

I don’t claim any medical knowledge. I’ve not taken the vaccines and don’t
intend to. But I have a question and hope it’s answerable. My wife’s 63 year old
brother, in the Philippines, very healthy person, got his second dose of Pfizer
two days ago. He collapsed there in the clinic and was rushed to the hospital.
He has no history of any medical issues. Sadly, his kidneys had immediately
started shutting down and he died less than two days later. I’m not looking for
pro or anti vaxx arguments, I respect whatever you choose for yourself and feel
that’s… Read more »

View Replies (4)

Dave
1 month ago

https://www.yahoo.com/news/pfiizer-picked-covid-19-vaccine-125332549.html

“Pfizer’s top scientist said it chose a relatively low COVID-19 vaccine dose to
minimize side effects.

Pfizer’s vaccine has 30 micrograms of mRNA, the active ingredient. Moderna’s has
100 micrograms.”

Or…… Pfizer is giving us less than 1/3rd the ingredients needed for great
protection, or Moderna is gonna cause us lots more side-effects….

Vaers does report More Moderna events than Pfizer events, supporting this (more
Pfizer doses given).
https://wonder.cdc.gov/

https://www.seattletimes.com/nation-world/new-data-confirm-pfizer-and-moderna-vaccines-bring-a-small-risk-of-heart-problems/

That said, the latest data shows an increased risk of Heart Problems after
Pfizer/Moderna vaccination, so those with current heart disease should weigh the
pros and cons.

View Replies (1)

Dave
1 month ago

https://doi.org/10.1056/NEJMoa2110475 Data from 2.4 million vaccinated Israelis
show that the “Pfizer” vaccine have these side-effects: “In short, the study has
shown that vaccination was strongly associated with an increased risk of
myocarditis (2.7 events per 100,000 persons), as well as lymphadenopathy (which
occurred relatively frequent with 78.5 events per 100,000 persons), herpes
zoster infection (which can translate to an increased risk of Bell’s palsy) and
appendicitis. On the other hand, SARS-CoV-2 infection was linked to a
substantially elevated risk of myocarditis (11 events per 100,000 persons),
alongside the risk of pericarditis, arrhythmia, pulmonary embolism, deep-vein
thrombosis, myocardial infarction, thrombocytopenia, and… Read more »

View Replies (2)

Sam
1 month ago

I had the Moderna shot just over two months ago and have suffered from burning
tingling sensations all over my body, including some dizziness and
light-headedness in the mornings off and on. Has anyone taken Gabapentin and if
so, has it worked or have you needed to keep upping your dosage? What about
natural treatments? Very frustrating and it’s waking me up all hours of the
night,,,,, suggestions???

Dave
1 month ago

https://japantoday.com/category/national/moderna-says-tainted-covid-vaccines-sent-to-japan-contained-steel
Steel particles found in some batches of Moderna in Japan. Don’t be surprised if
you got a jab with such batches and have side effects!

You can always ask the caregiver to visual check the vial for foreign particles
prior to giving you a dose.

View Replies (3)

Jay
1 month ago

I will be waiting for Novavax approval here in Canada. The phase trials looked
very good, and the amount of research and data available regarding protein sub
unit vaccines is comforting. Also, I love how they are using an adjuvant sourced
from a tree unlike from aluminum like post protein sub units have.

View Replies (1)

Jess
1 month ago

Hello!! I just wanted to get an update on how you guys are feeling. I’m in the
Oz and as with most ppl, we are being forced to take the vaccine. My dr has
advised me to take the Pfizer butbive had severe anxiety for the past few weeks
thinking about the thought of taking it. I’ve had severe anxiety and panic
attacks on the past to a point that I was admitted to hospital. I’m so so
terrified that this vaccine may trigger these or if I can handle getting these
again. My partner is booked to have his… Read more »

View Replies (2)

Dave
1 month ago

https://japantoday.com/category/national/Japan-halts-use-of-1.63-mil-Moderna-vaccine-doses-over-contamination

https://time.com/5955247/inside-biontech-vaccine-facility/

Don’t be too surprised if some of the side effects are due to manufacturing
defects of the vaccines.

After all, any 50,000 step process created literally on-the-fly in 2020 and
rushed out the door is bound to have a few things wrong.

The companies are improving the process over time, but any single error in a
50,000 step process can make a bad batch.

View Replies (1)

Jody
2 months ago

I have not been on here in a few months. I took Pfizer–second vaccine 3/15. I
was diagnosed with costochondritis prior to vaccine but it came and went. Over 5
months later, I have been diagnosed with thoracic radiculopathy-very rare and
intercostal neuralgia. My PCP in the beginning brought up vaccine side effects
and I agreed. I am bedridden and in chronic pain every day. My pain is a 10
plus, I have disc bulge at T6T7–thoracic MRI. I had thoracic ESI and trigger
points. Spinal surgeon wants to do one more ESI to rule out spine causing the
problem.… Read more »

View Replies (3)

Dave
2 months ago

https://twitter.com/washingtonpost/status/1425509755481563139?s=19

Survivor Corps founder Diana Berrent joins The Post to discuss the growing
number of people with long-haul COVID, the mounting medical challenges they face
and her own experience with lingering symptoms.

Reasons for vaccination…

View Replies (3)

Dave
2 months ago

https://www.heraldscotland.com/news/19442038.coronavirus-scotland-41-covid-deaths-date-among-fully-vaccinated-scots/
What’s important is the graph breakdown of those infected – unvaccinated vs
vaccinated. 65% of the infected were not vaccinated 35% of the infected were
vaccinated That’s 7 out of every 20 infected people got vaccinated! This simply
reflects the dropping efficacy of vaccines against new strains of covid. … And,
notice the 10000s infected! Vs Wuhan China. They shut the city down, burned out
the virus, and for about a year, no, that’s zero 0, infections until the delta
recently arrived. Then they tested all 11 million, and found a few dozen in
Wuhan (and a few hundred… Read more »

View Replies (1)

Dave
2 months ago

https://www.news-medical.net/news/20210806/Double-vaccinated-three-times-less-likely-to-test-positive-for-COVID-19-than-unvaccinated-says-study.aspx
Vaccine effectiveness is dropping fast. In the latest round of people studied in
the UK, “in round 13 (June 24 and July 12, 202 1), 44 percent of infections
happened in fully vaccinated people…” From the latest August data from LA County
health, 0.31% of the vaccinated tested positive (infected). That’s 1 person out
of 322 vaccinated STILL getting infected. Out of these 15,628 vaccinated and
infected, 446 died. Or 1 out of 33 infected AND vaccinated DIE. N95 or N100 mask
use, distancing, isolating, and simply not seeing anyone in person recommended
for the highest risk age groups,… Read more »

Dave
2 months ago

https://www.news-medical.net/news/20210806/Study-reports-on-COVID-19-vaccine-related-adverse-events-in-young-Japanese-population.aspx

In Japan, the latest data says:

“Vaccination at the workplace was administered to approximately 4,000 people.
About 0.5% of vaccine recipients had adverse events..”

So that’s 1 in 200 people suffering effects such as anaphylaxis.

View Replies (1)

Dave
2 months ago

https://www.nature.com/articles/d41586-021-02039-y Extremely detailed overview
of the way Covid virus attacks human cells, invades them, and the important
effects. One of the key differences between vaccination and infection in
creating immunity is syncytia covid infections. Syncytia occurs when several
cells fuse or bind together to create a “lump” of cells. This occurs in the
lungs in covid infections, but not from vaccinations. Widespread syncytia leads
to the extensive lung damage and inability to breathe well often seen in covid
patients (and this is aside from the damage caused when the patients often catch
pneumonia as a result of covid infection). Naturally,… Read more »

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Dave
2 months ago

https://www.news-medical.net/news/20210731/FDAs-accelerated-drug-approval-process-plagued-by-missing-efficacy-data-and-questionable-evidence.aspx
“Since the US Food and Drug Administration (FDA) established its accelerated
approval pathway for drugs in 1992, nearly half (112) of the 253 drugs
authorized have not been confirmed as clinically effective, an investigation by
The BMJ has found.” While we know the vaccine works to a degree (the recent
superspreading infections among the vaccinated reveal poor protection against
infection, but decent protection against death after infection among the
vaccinated – 1 in 100 among the infected vaccinated based on LA county data), we
still don’t know the extent of the short and long term side effects. …
That… Read more »

Dave
2 months ago

“Decreased appetite, lethargy, asthenia, malaise, night sweats, and
hyperhidrosis were new adverse events attributable to BNT162b2 (Pfizers mRNA
covid vaccine).”

“More BNT162b2 than placebo recipients reported local reactions, most commonly
mild-tomoderate injection site pain.”

“More BNT162b2 than placebo recipients reported systemic events, most commonly
fatigue. Systemic events were mostly mild-to-moderate, but occasionally severe.”

Efficacy dropped to 83.7% (74.7 to 89.9% range) after 4 months post-vaccination.

Importantly!
Right after the 2nd dose, the efficacy in some groups was poor.
Eg. Asians 87.6% (range as low as 58.9 to 96.6%).

https://www.medrxiv.org/content/10.1101/2021.07.28.21261159v1.full.pdf

Michele
2 months ago

Started having palpatations 3 days after 1st dose. Was just wondering for anyone
else who experienced palpatations how long did they last? And if you have since
had your 2nd dose, did you experience similiar side effects?

I’m 2 months out now and the palpatations have gotten better, I also
occasionally feel some shortness of breath. I’m nervous about getting the 2nd
shot now!

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