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ANIMAL RESEARCH


BREADCRUMB

 1. Home
 2. Animal Research


WHAT WE DO

Animal research at MU is overseen by three distinct groups: The Office of Animal
Resources (OAR), the Animal Care and Use Committee (ACUC) and the Animal Care
and Quality Assurance office (ACQA). Each has a specific role to ensure MU’s
animal research is conducted safely and humanely.

OFFICE OF ANIMAL RESOURCES (OAR)

We provide veterinary care for MU-owned animals and maintain campus animal
facilities. Our mission is to deliver the highest standard of husbandry,
well-being and health care for all MU animals.

Veterinary care

 * Provided 24 hours a day, seven days a week, 365 days a year to all animals on
   campus under the oversight of the attending veterinarian
 * Delivered by five full-time veterinarians, one part-time veterinarian, one
   veterinary technician and nine to 12 comparative medicine
   residents/post-doctoral veterinarians

Staff observe all animals daily. Concerns are reported directly to the OAR
veterinary team.

Husbandry and facilities management

 * OAR maintains multiple animal housing and support areas for common laboratory
   species as well as unique animal models.
 * Housing systems and biosecurity levels are available for diverse research
   projects and animal health statuses.
 * Experienced facility supervisors manage day-to-day operations and
   approximately 50 staff who provide exceptional animal care seven days a week,
   365 days a year.

Cost recovery

 * OAR is required to recover costs associated with the procurement, care and
   support of research animals.
 * Investigators are billed on a monthly basis.
 * The MoCode provided on the original animal order form will be charged.
 * Researchers can log in to see per diem rates and more information.

Technical services, investigator support and training

Experienced OAR staff support MU research programs by providing a variety of
services to investigators, including:

 * Technical assistance with all aspects of animal studies, from sample
   collection to performing entire experiments.
 * Animal transportation on campus and colony management.
 * Expertise from veterinarians about animal model selection, ACUC
   protocol/refinement and study planning.

These services are offered as cost-recovery fees using an hourly rate plus cost
of materials, if applicable.

We also offer training on animal use and technical procedures. Consultation and
most preliminary training are provided at no charge. 

Animal ordering and quarantine

All animal orders for investigators housing research animals in OAR-managed
facilities must go through the OAR office.

The OAR Office Support Assistant will process and place orders for all animals
coming from approved vendors. An approved, active ACUC protocol must be in place
for investigators to order animals. Animals from approved vendors may join an
investigator’s existing colony upon receipt.

Animals from non-approved vendors will be evaluated based on source and health
status and, if approved for receipt at MU, required to go through quarantine
period prior to joining an investigator’s existing colony. A request for
quarantine space needs to be submitted to the OAR Office Support Assistant who
will process the order. The OAR veterinary staff will then review the health
history of the animals and approve any incoming shipments. For more details on
the rodent quarantine process please see the OAR SOP Rodent Quarantine.

Animal export

OAR will assist with the process of shipping rodents to outside institutions.
Researchers can log in to learn more.

Drug supply/ordering

As a service to MU investigators, drugs (both controlled and non-controlled) and
various medical supplies may be ordered through OAR. Researchers can log in to
learn more.

ANIMAL CARE AND USE COMMITTEE (ACUC)

The ACUC ensures that all MU animal facilities are maintained and all personnel
are trained properly. The committee includes scientists, veterinarians,
nonscientists and community members who are responsible for reviewing and
approving the use of all vertebrate animals in research and teaching.

MU is required to have an ACUC as a registered institution of the U.S.
Department of Agriculture (USDA) and an assured institution of the Office of
Laboratory Animal Welfare (OLAW).

Animal research is regulated by two U.S. government entities:

 1. The USDA enforces the Animal Welfare Act. The university's USDA registration
    number is 43-R-0048.
 2. OLAW is part of the National Institutes of Health (NIH). To receive NIH
    funding, MU is required to assure with OLAW that we follow the Public Health
    Service Policy on Humane Care and Use of Laboratory Animals. Our OLAW
    assurance number is D16-00249. Standards and requirements are outlined in
    the:
    * “Guide for the Care and Use of Laboratory Animals”
    * “Guide for the Care and Use of Agricultural Animals in Research and
      Teaching”

ACUC function and authority

 * We review and approve vertebrate animal research and teaching activities (or
   changes to those activities). Before beginning studies involving animals,
   researchers must submit a description to the ACUC for review and approval.
 * At least once every six months, we review the research facility's program for
   humane care and use of animals.
 * At least every six months, we inspect all of MU’s animal facilities,
   including animal study areas.
 * We prepare evaluation reports and submit them to the research facility’s
   institutional official.
 * The committee reviews and investigates concerns involving the care and use of
   animals. These concerns can be the result of public complaints or from
   reports of noncompliance received from laboratory or research facility
   employees.
 * We make recommendations to the institutional official regarding any aspect of
   the research facility's animal program, facilities or personnel training.
 * The ACUC is authorized to suspend an activity involving animals.

ANIMAL CARE QUALITY ASSURANCE (ACQA) OFFICE

Our office provides support for the ACUC and animal researchers. We assure that
animal research and teaching are performed humanely, and all laws, rules and
guidelines are followed.

We also ensure that animal researchers and their laboratory personnel are
properly trained to perform animal research and are aware of the occupational
health and safety risks associated with using animals in research and teaching.

Reporting

We investigate concerns regarding the care and treatment of animals used in
research or teaching at MU.

To report a concern, please contact one of the following:

 * ACQA office: 573-882-1746 or acuc@missouri.edu
 * ACQA director: 573-882-3681
 * OAR Attending Veterinarian: 573-882-0638
 * Other ACUC members

 * For anonymous concerns, call 866-447-9821
   Notification of ACUC’s findings will not be given for anonymous reports.

Reports are kept confidential upon request.

Animal Welfare Act regulations prohibit discrimination or reprisal against any
person for reporting violations of any regulation or standard under the act.

Grants and contracts information

Information frequently requested by funding agencies:

 * Animal Welfare/PHS Assurance No. D16-00249
 * USDA Registration No. 43R0048
 * AAALAC Unit No. 487
 * Most recent AAALAC site visit date: 3/8/21
 * Most recent AAALAC accreditation date: 6/23/21
 * Initial AAALAC accreditation date: 5/23/79


CONTACT US

310 Jesse Hall
Email: acuc@missouri.edu Phone: 573-882-1746


ANIMAL RESEARCH

Protocol application eACUC Help & Documentation Per Diem Rates and Service
Charges Occupational Health & Safety Program (OHSP) Frequently asked questions
Other resources




RELATED LINKS

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CONTACT

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Columbia, MO 65211

Phone: 573-882-9500

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