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URL: https://pubpeer.com/publications/6DEA60BFD27902C139A7F57C0FE741
Submission Tags: falconsandbox
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 1. Home
 2. Publications

Mitochondrial-generated ROS down regulates insulin signaling via activation of
the p38MAPK stress response pathway
Molecular and Cellular Endocrinology (2016) - 2 Comments
doi: 10.1016/j.mce.2015.09.013  issn: 0303-7207  pubmed: 26454089 

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Rabab Al-Lahham , James H. Deford , John Papaconstantinou



#1 Actinopolyspora biskrensis commented May 2023


Could the authors help me understand what is going on here?

Signals outlined in pink and red in Figure 2F and Figure 3D appear unexpectedly
similar. Upper panel is published figure, lower panel is false color image using
ImageJ. Arrows identify possible splices (maroon, cyan, teal, purple and green).

Are the original uncropped scans available?

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#2 Actinopolyspora biskrensis commented May 2023


Perhaps another issue in Figure 8D. In this case there appears to be a
differential splice in the upper panel. Again, do the authors have the original
data?

There may be other similar issues in this paper, but I will await a response
from the authors on the availability of the data for review.

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