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   About Specs
   
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 * Compound Management 
   Why outsource
   
   Our services • Procurement • Reformatting • Warehousing • Compound storage •
   Quality control • On site / Off site • Cheminformatics
   
   Our clients
 * Research Compounds 
   Research compounds • Screening compounds • Natural products • Academic
   compounds • Pre-plated sets
   
   Online shop specs.net • Accessing data • User registration form
   
   Offer us your compounds


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CHEMICAL COMPOUNDS FOR THE LIFE SCIENCE INDUSTRY


BUILDING BLOCK COMPOUNDS SUITABLE FOR FURTHER SYNTHESIS


SHIPMENT OF COMPOUND SETS ALL OVER THE WORLD


WELL ORGANIZED AND EASILY ACCESSIBLE COMPOUND REPOSITORIES

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ABOUT SPECS

Specs, founded in 1987, is the world's leading provider of compound management
services and supplier of research compounds to the Life Science industry. The
compound management services are offered from our two main logistic centers in
The Netherlands and Maryland, USA. In these warehouses, millions of compounds
from our clients are stored under controlled environmental conditions and are
processed using state-of-the-art weighing stations, automated liquid handlers
and quality control devices.  After processing, the samples are distributed to
the end users on a daily basis all over the globe. Compound sourcing and
procurement is a service that our clients use for analog searching and library
enhancement.  Our synthesis lab can help out with custom synthesis or contract
research if compounds are not commercially available.

The Specs in-house 350.000+ screening compound repository consists of single
synthesized, well-characterized and drug-like small molecules and has been built
through global acquisition programs utilizing a network of more than 2,000
academic sources worldwide. These compounds are available for ordering online
through www.specs.net. Pre-selected targeted or diverse libraries are available
in various formats and library sizes.  Our cheminformatic service can help with
target specific selections for lead discovery and optimization programs and
design of new chemical entities. Specs has a 30+ years proven track record in
every aspect of compound management. Our combined services makes Specs uniquely
qualified as a reliable outsource partner for compound libraries and logistics.


READ THE FULL SPECS STORY



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RESEARCH PARTNERSHIPS

Drug discovery is a costly and time-consuming process. Although large
pharmaceutical companies have both money and resources to support their
screening activities, academic research groups and small biotech start-up
companies usually struggle to find suitable funding to support their promising
and innovative screening platforms. Specs is the ideal partner to provide
chemistry and chemistry related services in either a shared risk collaboration
or in a grant funded project. 

Our value-added services include:
• Hit discovery – access to targeted, focussed or diverse sets of screening
compounds from our 350.000+ compound repository.

• Hit confirmation – converged set of analogues, early SAR and patentability
studies.

• Hit expansion – additional hit analogues from Specs’ stock, third party
vendors and our extensive network of more than 2,000 academic sources from more
than 45 countries worldwide by e.g. scaffold hopping, pharmacophore searching
etc.



• Hit to Lead - design and synthesis of compounds to optimize drug-likeness,
ADMET properties, potency, cytotoxicity, serum binding, stability and
formulation studies
for in vivo experiments.

• Lead optimization - design and synthesis of compounds to
improve pharmacokinetics, pharmacodynamics, in-vivo efficacy and reduce unwanted
side effects. 

We always welcome the opportunity to enter into new screening partnerships. 
Specs has a proven track record in national and international projects.

Several examples of our current and past collaborations are:
• Alion Pharmaceuticals – Oncology and CNS programs
• Oncodrone – Prostate cancer metastasis and Oncology program
• OcellO – Polycystic kidney disease program
• University Medical Centre Utrecht – Growth hormone receptor inhibitors to cure
cancer 
• Thrombotargets – Anticoagulant program 




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