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Text Content

 * About
 * EasyTIVA
 * Publications
 * Team
 * Contact


   
 * Closed loop anesthesia
   Active clinical research field since the 50's Now mature and clinically
   validated Delivers faster patient recovery with less PONV
   
 * Closed loop anesthesia
   Outperforms manual control of EEG Suitable for all patients and all surgeries
   Requires anesthesiologist supervision
   
 * EasyTIVA
   Our technology platform for closed loop TIVA Full automation of both the
   induction and regulation Co-administration of Propofol and Remifentanil
   
 * Developing a reference design device A new generation of tools for
   anesthesiologists Open for technical and clinical cooperation
   EasyTIVA




Slide

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ABOUT

Medsteer, with offices in Paris/France (HQ) and New York/USA, is a leading
technology provider in the field of closed loop systems for the delivery of
anaesthesia drugs. The company’s patented technologies focus on drug delivery
solutions guided by the cortical activity of the patient.

Providing full automation and customization to the individual patient’s needs,
closed loop anaesthesia opens up the way to a wide array of patient benefits
associated with personalized medicine.

 

 




EASYTIVA

EasyTIVA is a patented technology delivering full automation in the dosage of
Propofol and Remifentinal. EasyTIVA is a mature technology validated by a broad
and solid base of patient inclusions across numerous multicenter clinical trials
(over 15 000). Both the induction and the regulation are supported for all
patients and all surgeries.



Non-invasive disposable sensors on the forehead of the patient provide real-time
information about the cortical activity.

Using the real-time cortical activity, the brain monitor delivers a depth of
anaesthesia index. This is often represented by a value between 0 and 100.

EasyTIVA can operate with various brain monitor systems available on the market.
Main suppliers are Medtronic, GE Healthcare.

Leveraging the depth of anaesthesia index, EasyTIVA uses its patented algorithm
to deliver full automation in the dosage of Propofol and Remifentanil during the
entire surgery.

Using regular syringe pumps into a closed loop architecture, the exact amount of
anesthesia drugs are delivered to the patient at the right time, duration and
flowrate.


PUBLICATIONS

Since 2006 we have been engaged in 25 clinical trials around the world which
have been documented in a large number of scientific publications.

2006

Feasibility of closed-loop titration of propofol guided by the Bispectral Index
for general anaesthesia induction: a prospective randomized study.

European Journal of Anaesthesiology 23: 465–469

Titration of Propofol for Anesthetic Induction and Maintenance Guided by the
Bispectral Index: Closed-loop versus Manual Control. A Prospective, Randomized,
Multicenter Study.

Anesthesiology 104:686–95

2007

Closed-loop administration of propofol and remifentanil guided by the Bispectral
Index in patient requiring an emergency lung volume reduction.

Paediatric Anaesthesia 17: 909-10

2008

Closed-Loop Control of Consciousness During Lung Transplantation: An
Observational Study Journal of Cardiothoracic and Vascular

Anesthesia & Analgesia 22: 611-615

2009

Closed-loop titration of propofol and remifentanil guided by Bispectral Index in
a patient with extreme gigantism.

Journal of Clinical Anesthesia 21: 542-4

2011

Closed-Loop Coadministration of Propofol and Remifentanil Guided by Bispectral
Index: A Randomized Multicenter Study.  This publication was accompanied with an
editorial

Anesthesia & Analgesia 112: 546-57

Occurrence of and risk factors for electroencephalogram burst suppression during
Propofol–Remifentanil anaesthesia.

British Journal of Anaesthesia 107: 749–56

2012

Feasibility of Closed-loop Titration of Propofol and Remifentanil Guided by the
Spectral M-Entropy Monitor.  This publication was accompanied with an editorial

Anesthesiology 116:286-95

2013

Automated sedation outperforms manual administration of propofol and
remifentanil in critically ill patients with deep sedation: a randomized phase
II trial.

Intensive Care Medecine 39: 453-62

Automatic administration of propofol and remifentanil guided by the Bispectral
index during rigid bronchoscopic procedures: a prospective randomized trial.

Canadian Journal of Anaesthesia 60: 881-887

2014

Automated titration of propofol and remifentanil decreases the
anesthesiologist’s workload during vascular or thoracic surgery: a randomized
prospective study.

Journal of Monitoring and Computing 28; 35-40

Comparison of different formulations of propofol: A randomized, double-blind
trial using a closed-loop administration

Anesthesiology 120: 355-64

No clinically relevant sparing effect of Nitrous oxide on propofol-remifentanil
anesthesia administered automatically guided by the Bispectral index. A
randomized multicenter study.

British Journal of Anaesthesia 112: 842-51

Sparing effect of dexmedetomidine on propofol and remifentanil requirements
during Bispectral Index   guided closed-loop controlled anesthesia: A
double-blind, placebo-controlled study.

Anesthesia & Analgesia 118: 946-55

2015

Feasibility of Closed-loop Co-administration of Propofol and Remifentanil Guided
by the Bispectral Index in Obese Patients: A Prospective Cohort Comparison.

British Journal of Anaesthesia 114: 605-14

Feasibility of Closed-loop Titration of Propofol and Remifentanil Guided by the
Bispectral Monitor in Pediatric and Adolescent Patients: A Prospective
Randomized Study.

Anesthesiology 122: 759-67


TEAM

The Medsteer founders, management team and board members combine internationally
recognised anesthesiology expertise, with seasoned business leadership and an
entrepreneurial mindset.

NICOLAS CHOUSSAT

Chief Operating Officer

 * 

DR. THIERRY CHAZOT

Chief Executive Officer

 * 

DR. NGAI LIU

Chief Medical Officer

 * 

CONTACT

Medsteer SAS

40 Rue Worth

92151 Suresnes

E: info@medsteer.com

T: +33 183 62 78 18

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