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3141-26-2

3,4-Dibromothiphene is used in the synthesis of thiophene-estrogen receptor
ligands which contain superagonist activities when involving luciferase in genes
in human cells giving 2-3 times the activit y of estradiol. Also used in the
synthesis of supercapacitors for use as charge storage applications.

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80-59-1

Tiglic acid, also known as tiglate or tiglinsaeure, belongs to the class of
organic compounds known as methyl-branched fatty acids. These are fatty acids
with an acyl chain that has a methyl branch. they are saturated and contain only
one or more methyl group. However, branches other than methyl may be present.

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271-63-6

7-Azaindole is imidazolinone derivatives as CGRP receptor antagonists used in
the treatment.

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516-12-1

N-Iodosuccinimide is a iodo substituted succinimide that is used as an
iodinating agent in chemical synthesis.

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1094-61-7

Nicotinamide ribotide is slightly soluble (in water) and a moderately acidic
compound (based on its pKa). Nicotinamide ribotide has been found in human
placenta tissue, and has also been detected in multiple biofluids, such as urine
and blood.

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1191237-69-0

GS-441524 is an antiviral nucleoside analog and the active metabolite of
remdesivir (Item No. 30354).1 Upon entry into cells, GS-441524 is metabolized to
an active triphosphate form that induces RNA chain termination and inhibits
viral polymerases.

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7436-22-8

MethylaMine-d3 Hydrochloride is useful in preparation of deuterated diphenylurea
derivatives as phosphokinase inhibitors.

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73183-34-3

It is a colourless solid that is soluble in organic solvents. It is a
commercially available reagent for making pinacol boronic esters for organic
synthesis. Unlike some other diboron compounds, B2pin2 is not moisture-sensitive
and can be handled in air.

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AMINO ACIDS

Amino acids are the building blocks of peptides and proteins. All amino acids
contain an amine group, a carboxylic acid group, and a side-chain that varies
for each amino acid. The side chains differ in polarity and pKa and are
important to both protein structure and function.


BORONIC ACIDS

Boronic acid is a stable and generally a non-toxic group that is easily
synthesized and, due to these features, can be used in several synthetic
reactions including metal-catalyzed processes such as Suzuki–Miyaura reaction,
acid catalysis, asymmetric synthesis of amino acids, and hydroboration.


CHIRAL COMPOUNDS

Chiral molecules show left and right-handed nature in the sense that the
molecules may exist as mirror-image forms that cannot be made to overlap by any
amount of rotation.


FLUORINATED COMPOUNDS

Fluorine is the most electronegative of all the elements, and forms very strong
bonds to carbon and most other elements. Its small atomic radius enables
replacement of one or more hydrogen atoms in an organic structure by fluorine
with relatively little steric impact, but often with a profound influence on the
stability, biological availability and activity of the resulting molecule.
Elemental fluorine is one of the most chemically reactive substances known,
which, along with the high toxicity of both fluorine and hydrogen fluoride, and
their incompatibility with common materials, including glass, necessitate highly
specialized equipment and techniques for reactions in which they are involved.
Direct fluorination of a pre-existing organic structure with either F2 or HF may
thus appear daunting to the non-specialist.


HETEROCYCLIC COMPOUNDS

Heterocyclic compounds are frequently used in organic synthesis. Many of the
heterocyclic scaffolds have been identified as a privileged structure in
medicinal chemistry and are prevalent in a variety of pharmacologically active
synthetic and natural compounds. Most chemical reaction design planning starts
from these commercially available heterocyclic building blocks.


LABELED COMPOUNDS

Stable isotopically labeled compounds are non-radioactive chemical substances
where one or more element within a compound has been substituted for its stable
isotope. Common stable isotopes used in research include 2H (Deuterium or D),
13C, 15N and 18O.


PYRIDINES

Pyridine is the basic heterocyclic compound of the azine kind. Pyridine is
derived from benzene through replacement of the CH group by the N-atom. Pyridine
and picolines are employed as bases, scavengers, catalysts, as well as solvents
for chemical reactions.


PEG LINKERS

Polyethylene glycol is a biologically inert, non-immunogenic chemical that
confers greater water solubility to proteins, labeling tags and crosslinkers
with which it is incorporated as constituent chemical group. PEG linkers are
widely used in pharmaceutical and biotech R&D due to their aqueous solubility
and non-immunogenicity.

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