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801 E Campbell Road Suite 400 | Richardson, TX 75081 | (214) 308-0248 - (888)
768-6869

IBIS (International Breast Cancer Intervention Study)
Online Tyrer-Cuzick Model Breast Cancer Risk Evaluation Tool



ABOUT IKONOPEDIA

Ikonopedia is a next-generation cloud-based breast reporting and MQSA management
system designed to track individual lesions to full resolution. Ikonopedia’s
closed-loop system ensures patient safety, reporting efficiencies and
radiologist awareness with important clinical warnings and timely alerts for
pertinent patient and family history.

Ikonopedia was founded by expert breast radiologists: László Tabár, MD, a world
renowned educator; A. Thomas Stavros, MD, the author of one of the most popular
reference books for breast ultrasound; and Michael J. Vendrell, MD, expert in
breast MRI and CAD design.

Click here for more information about Ikonopedia


ABOUT IBIS

This risk assessment tool was developed by scientists at the Wolfson Institute
of Preventive Medicine, Queen Mary University of London and is provided for
non-commercial research purposes only. No responsibility is accepted for
clinical decisions arising from its use.

Commercial use requires a license, for further information contact:
TyrerCuzick@cancer.org.uk

For technical support related to the site contact: support@ikonopedia.com


IBIS RISK ASSESSMENT TOOL V8.0B

This tool estimates the likelihood of a woman developing breast cancer
specifically within 10 years of her current age and over the course of her
lifetime. The tool is utilized to inform women and help support the decision
making process for genetic counseling and testing.

The risks provided account for competing mortality, so there is allowance for
death from other causes than breast cancer.

Note: This tool is not intended to assess the risk for women who have already
been diagnosed with breast cancer.
System of Measurement:
 * Imperial Units
 * Metric Units

Breast Density Measure:
 * Unknown
 * Volpara
 * VAS
 * BI-RADS® ATLAS*

Personal History: Please enter the woman's age, weight and height below...
Current Age:

Weight:
kg
Height:
meters
Weight:
lbs
Height:
Feet:

Inches:

Breast Density, if known
Breast Density, if known
 * SKIP
 * Fatty
 * Average
 * Heterogeneously Dense
 * Extremely Dense

What was the woman's age at the time of her first menstrual period?
Has the woman given birth to one or more children?
 * Unknown
 * No
 * Yes

Woman's age when she delivered her FIRST live birth?
Has the woman gone through menopause?
 * Don't Know
 * No
 * Yes
 * In Menopause Now

At what age was menopause?
Hormone Replacement Therapy (HRT) Usage?
 * Never
 * Stopped use 5 or more years ago
 * Stopped use less than 5 years ago
 * Current User

Estrogen only or Combined Treatment?
 * Unknown
 * Estrogen Only
 * Combined

Length (in years) of HRT use?
 * Unknown
 * 1 Year
 * 2 Years
 * 3 Years
 * 4 Years
 * 5 Years
 * 6 Years
 * More then 6 Years

If NOT current user, how many years ago did the woman last use HRT?
 * Unknown
 * 0 Years
 * 1 Year
 * 2 Years
 * 3 Years
 * 4 Years
 * 5 Years

If current user, how long does the woman intend to be using HRT?
 * Unknown
 * 1 Year
 * 2 Years
 * 3 Years
 * 4 Years
 * 5 Years
 * 6 Years
 * More then 6 Years

BRCA Gene: Does the woman have a mutation in either the BRCA1 or BRCA2 gene?
 * Unknown
 * Tested, Normal
 * BRCA1+
 * BRCA2+

Ovarian Cancer: Has the woman had OVARIAN cancer?
 * No
 * Yes

At what age was she diagnosed?
Age at Diagnosis:
Breast Biopsy: Has the woman had a breast biopsy?
 1. No prior biopsy / no proliferative disease
    
    
 2. Prior biopsy, result unknown
    
    
 3. Hyperplasia (not atypia)
    
    
 4. Atypical Hyperplasia
    
    
 5. Lobular Carcinoma in Situ (LCIS)
    
    

Family History:
Family history is an important factor in determining risk, especially if there
is a history of breast or ovarian cancer in the woman's family.
Ashkenazi Inheritance?
 * No
 * Yes

To add a family member to the woman's family history, click the "Add Family
Member" button below
Add Family Member
Mother
Remove
Current Age or Age at death?
Breast Cancer?
 * No
 * Yes

Mother's age at onset?
Bilateral?
 * No
 * Yes

Mother's age at diagnosis of 2nd breast?
Ovarian Cancer?
 * No
 * Yes

Mother's age at onset?
BRCA Gene:
 * Unknown
 * Tested, Normal
 * BRCA1+
 * BRCA2+

Father
Remove
Breast Cancer?
 * No
 * Yes

BRCA Gene:
 * Unknown
 * Tested, Normal
 * BRCA1+
 * BRCA2+

Sister
Remove
Current Age or Age at death?
Breast Cancer?
 * No
 * Yes

Sister's age at onset?
Bilateral?
 * No
 * Yes

Sister's age at diagnosis of 2nd breast?
Ovarian Cancer?
 * No
 * Yes

Sister's age at onset?
BRCA Gene:
 * Unknown
 * Tested, Normal
 * BRCA1+
 * BRCA2+

Does this sister have a daughter with a history of breast or ovarian cancer?
Add Niece
Niece
Remove
Current Age or Age at death?
Breast Cancer?
 * No
 * Yes

Niece's age at onset?
Bilateral?
 * No
 * Yes

Niece's age at diagnosis of 2nd breast?
Ovarian Cancer?
 * No
 * Yes

Niece's age at onset?
BRCA Gene:
 * Unknown
 * Tested, Normal
 * BRCA1+
 * BRCA2+

Daughter
Remove
Current Age or Age at death?
Breast Cancer?
 * No
 * Yes

Daughter's age at onset?
Bilateral?
 * No
 * Yes

Daughter's age at diagnosis of 2nd breast?
Ovarian Cancer?
 * No
 * Yes

Daughter's age at onset?
BRCA Gene:
 * Unknown
 * Tested, Normal
 * BRCA1+
 * BRCA2+

Brother
Remove
Breast Cancer?
 * No
 * Yes

Do any of the woman's brothers have a daughter with a history of breast or
ovarian cancer?
Add Niece
Niece
Remove
Current Age or Age at death?
Breast Cancer?
 * No
 * Yes

Niece's age at onset?
Bilateral?
 * No
 * Yes

Niece's age at diagnosis of 2nd breast?
Ovarian Cancer?
 * No
 * Yes

Niece's age at onset?
BRCA Gene:
 * Unknown
 * Tested, Normal
 * BRCA1+
 * BRCA2+

Paternal Grandmother
Remove
Current Age or Age at death?
Breast Cancer?
 * No
 * Yes

Paternal Grandmother's age at onset?
Bilateral?
 * No
 * Yes

Paternal Grandmother's age at diagnosis of 2nd breast?
Ovarian Cancer?
 * No
 * Yes

Paternal Grandmother's age at onset?
BRCA Gene:
 * Unknown
 * Tested, Normal
 * BRCA1+
 * BRCA2+

Paternal Aunt
Remove
Current Age or Age at death?
Breast Cancer?
 * No
 * Yes

Aunt's age at onset?
Bilateral?
 * No
 * Yes

Aunt's age at diagnosis of 2nd breast?
Ovarian Cancer?
 * No
 * Yes

Aunt's age at onset?
BRCA Gene:
 * Unknown
 * Tested, Normal
 * BRCA1+
 * BRCA2+

Does this aunt have a daughter with a history of breast or ovarian cancer?
Add Cousin
Cousin
Remove
Current Age or Age at death?
Breast Cancer?
 * No
 * Yes

Cousin's age at onset?
Bilateral?
 * No
 * Yes

Cousin's age at diagnosis of 2nd breast?
Ovarian Cancer?
 * No
 * Yes

Cousin's age at onset?
BRCA Gene:
 * Unknown
 * Tested, Normal
 * BRCA1+
 * BRCA2+

Paternal Half-Sister
Remove
Current Age or Age at death?
Breast Cancer?
 * No
 * Yes

Half-Sister's age at onset?
Bilateral?
 * No
 * Yes

Half-Sister's age at diagnosis of 2nd breast?
Ovarian Cancer?
 * No
 * Yes

Half-Sister's age at onset?
BRCA Gene:
 * Unknown
 * Tested, Normal
 * BRCA1+
 * BRCA2+

Paternal Uncle's Daughter
Remove
Current Age or Age at death?
Breast Cancer?
 * No
 * Yes

Cousin's age at onset?
Bilateral?
 * No
 * Yes

Cousin's age at diagnosis of 2nd breast?
Ovarian Cancer?
 * No
 * Yes

Cousin's age at onset?
BRCA Gene:
 * Unknown
 * Tested, Normal
 * BRCA1+
 * BRCA2+

Maternal Grandmother
Remove
Current Age or Age at death?
Breast Cancer?
 * No
 * Yes

Maternal Grandmother's age at onset?
Bilateral?
 * No
 * Yes

Maternal Grandmother's age at diagnosis of 2nd breast?
Ovarian Cancer?
 * No
 * Yes

Maternal Grandmother's age at onset?
BRCA Gene:
 * Unknown
 * Tested, Normal
 * BRCA1+
 * BRCA2+

Maternal Aunt
Remove
Current Age or Age at death?
Breast Cancer?
 * No
 * Yes

Aunt's age at onset?
Bilateral?
 * No
 * Yes

Aunt's age at diagnosis of 2nd breast?
Ovarian Cancer?
 * No
 * Yes

Aunt's age at onset?
BRCA Gene:
 * Unknown
 * Tested, Normal
 * BRCA1+
 * BRCA2+

Does this aunt have a daughter with a history of breast or ovarian cancer?
Add Cousin
Cousin
Remove
Current Age or Age at death?
Breast Cancer?
 * No
 * Yes

Cousin's age at onset?
Bilateral?
 * No
 * Yes

Cousin's age at diagnosis of 2nd breast?
Ovarian Cancer?
 * No
 * Yes

Cousin's age at onset?
BRCA Gene:
 * Unknown
 * Tested, Normal
 * BRCA1+
 * BRCA2+

Maternal Half-Sister
Remove
Current Age or Age at death?
Breast Cancer?
 * No
 * Yes

Half-Sister's age at onset?
Bilateral?
 * No
 * Yes

Half-Sister's age at diagnosis of 2nd breast?
Ovarian Cancer?
 * No
 * Yes

Half-Sister's age at onset?
BRCA Gene:
 * Unknown
 * Tested, Normal
 * BRCA1+
 * BRCA2+

Maternal Uncle's Daughter
Remove
Current Age or Age at death?
Breast Cancer?
 * No
 * Yes

Cousin's age at onset?
Bilateral?
 * No
 * Yes

Cousin's age at diagnosis of 2nd breast?
Ovarian Cancer?
 * No
 * Yes

Cousin's age at onset?
BRCA Gene:
 * Unknown
 * Tested, Normal
 * BRCA1+
 * BRCA2+

--------------------------------------------------------------------------------

Breast Cancer Risk Assessment (TC Model)
Risk Assessment data will become available when the patient questionnaire is
completed.
Ten Year Risk:
This woman (age 35): 1.7%
Average woman (age 35): 0.3%
Lifetime Risk:
This woman (to age 85): 39.1%
Average woman (to age 85): 12.6%




--------------------------------------------------------------------------------

Clear Risk Factors
Calculate Risk
Grandmother
Aunt
Half Sister
Uncle's Daughter
Grandmother
Aunt
Half Sister
Uncle's Daughter
Mother
Father
Sister
Daughter
Brother





* A registered trademark of American College of Radiology. All Rights Reserved.
The developer of this product is independently owned and operated, and is not an
affiliate of the American College of Radiology. The American College of
Radiology is not responsible for the contents or operation of this product or
its associated software, and expressly disclaims any and all warranties and
liabilities, expressed or implied, in connection therewith.