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International Conference on Civil and Architectural Engineering 2025

Potential Breakthrough in Obesity Drugs: Targeting Brain Neurons to Avoid Nausea

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Latest Medical Articles




UNUSUAL BLEEDING DURING AND AFTER PREGNANCY

When should pregnant women be concerned? Awareness of the dangers associated
with abnormal bleeding during pregnancy and after childbirth can be lifesaving
for both women and their babies.

Dr. Mzuvele Archwell Hlabisa, an obstetrician and gynaecologist at Netcare
Kingsway Hospital, emphasizes that while many people are unaware that over a
third of pregnant women may experience bleeding for various reasons, it is
crucial to determine the exact cause.

"Although some bleeding is normal in the postpartum period, excessive bleeding
can be life-threatening. It is often difficult for women to discern if their
bleeding is normal or not, but a good rule of thumb is to have any bleeding
during pregnancy checked by a healthcare professional," says Dr. Hlabisa.

He notes that around 35% of women experience bleeding in the first trimester.
"As the pregnancy progresses, the likelihood of bleeding decreases, so it’s
reassuring when women reach the mid-trimester, from 13 to 28 weeks of
gestation."

Bleeding could indicate a miscarriage or a threatened miscarriage, and severe
pain with bleeding could be related to placental abruption, a serious condition
where the placenta prematurely separates from the womb. These conditions require
immediate medical assessment.

Spotting In early pregnancy, some women may experience spotting, known as
implantation bleeding, when the embryo implants in the uterine wall. ...Read
full article



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Global Medical News


Study Finds Reminders Can Prevent Age-Related Memory Decline
A recent study from the University of Texas at Arlington reveals that setting
reminders can help eliminate certain age-related memory declines. The research
offers an important advancement in addressing cognitive challenges faced by
older adults, particularly in prospective memory, which involves remembering to
complete tasks at the appropriate time, such as taking medication or attending
appointments.

Prospective memory is crucial for everyday living and maintaining independence,
especially for aging individuals. Failure to recall these future-oriented tasks
can have serious consequences, as previous studies have shown that this type of
memory tends to weaken with age.

Hunter Ball, an associate professor of psychology at UTA and lead author of the
study, collaborated with psychologists from Arizona State University to conduct
two experiments. These experiments tested the prospective memory of younger and
older adults under various conditions, with or without the use of reminders.
Participants were tasked with remembering specific actions while engaging in
ongoing activities, with their performance assessed in both high-load (more
tasks) and low-load (fewer tasks) scenarios.

In the first experiment, participants were asked to remember specific tasks,
such as responding to particular words, with some receiving on-screen reminders.
Results showed no significant age-related decline in prospective memory under
low load without reminders. However, in high-load conditions, both younger and
older adults showed similar improvement when reminders were used, suggesting
that reminders help reduce cognitive strain by offloading the need to rely
entirely on internal memory.

The second experiment introduced more complex tasks that required participants
to recognize broader categories, like animals or fruits, rather than specific
words. Without reminders, older adults had more difficulty remembering these
tasks in high-load conditions. However, the performance gap between younger and
older adults disappeared when reminders were available, underscoring the
potential of reminders to mitigate memory challenges in older adults, especially
for cognitively demanding tasks.

According to Ball, reminders are particularly effective for older adults because
they tend to check them more frequently when faced with high cognitive demands.
This compensatory behavior helps older adults manage tasks that might otherwise
overwhelm their internal memory resources.

The implications of this study reach beyond the laboratory. Prospective memory
is essential in real-world settings, and with an aging population, finding
practical solutions to memory challenges is increasingly important. The
researchers highlight that digital tools, such as smartphone apps, personal
assistants like Amazon Alexa, or simple reminder notes, can be valuable aids for
older adults in managing their daily responsibilities and maintaining their
independence.

“This study shows that cognitive offloading, like using reminders such as cell
phone calendars, can effectively reduce memory challenges in older adults,” said
Ball. “Although our study was conducted in a controlled environment, these
findings are easily applicable in everyday life, providing a simple and
effective way to alleviate the burden of prospective memory issues in older
adults."







October 25,2024


Cholera Crisis Deepens Amid Ongoing Conflict in Sudan
Sudan's health ministry has reported over 430 cholera-related deaths in the past
month, as the country remains engulfed in civil war. The number of infections
has surged to approximately 14,000. The ministry emphasized its efforts to
combat the cholera outbreak in affected states, but the ongoing conflict
complicates treatment delivery. US special envoy for Sudan, Tom Perriello,
estimates that around 150,000 people have lost their lives since the war began
in April 2023. M�decins Sans Fronti�res (MSF) has highlighted significant
challenges in their humanitarian response due to obstructions from both warring
factions, resulting in inadequate assistance for those in need. In a recent
report, MSF noted the collapse of Sudan's health system, with alarming rates of
maternal and neonatal mortality. The conflict stems from a power struggle
between the army and the Rapid Support Forces (RSF), which has led to what the
UN describes as one of the worst humanitarian crises globally. More than nine
million people have been displaced, and there are growing concerns of widespread
famine due to failed agricultural activities. Warnings of potential genocide
against non-Arab communities in Darfur have also emerged. Cholera, a
fast-spreading and highly infectious disease, can lead to severe dehydration and
death if not treated promptly. While it is relatively easy to treat, immediate
care is crucial. Health Minister Haitham Mohammed Ibrahim declared a cholera
outbreak in mid-August, exacerbated by heavy rainfall, flooding, and
overcrowding in displacement camps. MSF emergency coordinator Esperanza Santos
described the situation as a "perfect storm" for cholera proliferation. In some
regions, schools, markets, and shops have been ordered to close to mitigate the
disease's spread. MSF reported 114 maternal deaths in South Darfur alone between
January and August, with many children facing starvation. The organization
warned that the conditions in South Darfur likely reflect a broader crisis
across isolated, war-torn areas of Sudan. Dr. Gillian Burkhardt, MSF's sexual
and reproductive health manager in South Darfur, expressed deep concern,
stating, "This is a crisis unlike any other I have seen in my career."
September 30, 2024


Patient Faces Ongoing Struggles After Ozempic Treatment
Dana Filmore was initially terrified of taking Ozempic due to her fear of
needles. The thought of injecting herself in the stomach with this diabetes
medication seemed daunting. However, after her antidiabetic pills failed to
adequately manage her blood sugar, her doctor recommended Ozempic, which is
FDA-approved for treating Type 2 diabetes. Filmore, a 55-year-old grandmother
from Columbus, decided to take the plunge. She began using Ozempic but stopped
six months ago due to troubling side effects. Now, three years later, she has
been diagnosed with gastroparesis�stomach paralysis�which can be a potential
side effect of the drug. Since discontinuing the injections, she has struggled
with eating and digestion. Gastroparesis affects the stomach�s ability to
contract, causing food to remain in the stomach longer than normal. This often
leads to severe symptoms such as vomiting and diarrhea. Filmore�s experience
highlights the serious risks associated with Ozempic, raising important
questions about the medication's long-term effects.
September 27, 2024


Musk Advocates for Accessibility of GLP-1 Drugs Amid High Prices in the U.S.
Recent treatments that mimic a hormone regulating appetite and blood sugar have
proven highly effective for obesity and type 2 diabetes management. The most
notable GLP-1 medications available are Ozempic and Wegovy, both developed by
Danish pharmaceutical company Novo Nordisk. Elon Musk recently shared on X, the
social media platform he owns, that addressing obesity significantly lowers the
risk of related diseases, particularly diabetes, and enhances overall quality of
life. He emphasized the need to make appetite-suppressing medications accessible
to everyone. His comments came in response to Senator Bernie Sanders, who noted
that generic drug manufacturers claim they could offer these medications for
less than $100 a month. Currently, the list price in the U.S. for Ozempic is
$968.52 and for Wegovy, it�s $1,349.02. In contrast, these drugs are much more
affordable in other countries, with Ozempic priced at just $59 in Germany and
Wegovy at $92 in the U.K. Musk remarked, �I don�t often agree with Bernie on
many issues, but I do on this one.� During a recent Senate hearing, Senator
Sanders questioned Novo Nordisk CEO Lars Fruergaard J�rgensen about the
company�s pricing strategies for these high-demand drugs in the U.S. He
highlighted that since 2018, Novo Nordisk has earned $50 billion from Ozempic
and Wegovy, with a staggering 72% of that revenue generated from U.S. sales.
Sanders stated, �In other words, the United States is Novo Nordisk�s cash cow
for Ozempic and Wegovy.� He even quoted Musk�s tweet, acknowledging, �Mr. Musk
is right.�
September 26, 2024


Global Rise in Short-Sightedness Among Children Linked to Lockdowns and Screen
Time
A global analysis reveals that children's eyesight is deteriorating, with one in
three now experiencing short-sightedness, or myopia. Researchers suggest that
the Covid lockdowns contributed significantly to this decline, as children spent
more time on screens and less time outdoors. Myopia is becoming a pressing
global health issue, with projections indicating that millions more children
will be affected by 2050. The study highlights alarming rates in Asia, where 85%
of children in Japan and 73% in South Korea are short-sighted, along with over
40% in China and Russia. In contrast, countries like Paraguay and Uganda report
some of the lowest levels of myopia, around 1%, while the UK, Ireland, and the
US have rates close to 15%. Published in the British Journal of Ophthalmology,
the study analyzed data from over five million children and teenagers across 50
countries on all six continents. The findings show that short-sightedness has
tripled from 1990 to 2023, now affecting 36% of children, with a particularly
significant spike observed following the pandemic. Myopia typically begins in
primary school and can worsen until the eye stops growing around the age of 20.
Factors influencing its prevalence include geographic location, genetics, and
educational practices. In East Asia, where formal education often begins as
early as age two, children spend more time focusing on books and screens,
straining their eye muscles and increasing the risk of developing myopia. In
contrast, in Africa, where schooling generally starts at ages six to eight, the
prevalence of myopia is seven times lower than in Asia.
September 25, 2024


Junk Food Advert Bans on Public Transport to Combat Childhood Obesity
Junk food advertisements will be prohibited on select bus and train services as
part of a new initiative aimed at reducing childhood obesity. The North East
joins nine other regions in this effort, banning unhealthy food promotions on
the Metro and bus services. Mayor of the North East, Kim McGuinness, emphasized
that "enough is enough," labeling the targeting of children with such adverts as
"predatory." The AdEnough campaign, initiated by chef Jamie Oliver, supports
this move, stating it is a "vital step" due to the constant bombardment of
unhealthy food messaging aimed at children. This ban will be adopted by mayors
in Greater Manchester, Liverpool, North Yorkshire, South Yorkshire, West
Yorkshire, Cambridgeshire and Peterborough, and the West Midlands. Recent
reports from Newcastle City Council reveal that 11% of reception-age children
and 26% of those in year six in the North East are classified as obese. National
statistics indicate that over one in five children in England are overweight or
obese by the time they start primary school, with that figure rising to more
than one in three by the time they finish. McGuinness stated that this pledge
sends a strong message to junk food companies and aligns with broader national
efforts to curb junk food advertising. The implementation will follow her plans
to regain control of buses from private operators. Greater Manchester Mayor Andy
Burnham remarked that young people deserve "the best possible start in life,"
commending the initiative as a challenge to junk food corporations. The ban is
already operational on London�s tubes and buses. Jamie Oliver praised the mayors
for their proactive stance, calling it a "much-needed and vital step towards
creating healthier, happier communities" in the UK, though he noted that more
work is needed to address unhealthy food messaging. Additionally, it was
recently announced that online junk food adverts will be banned starting next
year, alongside restrictions on TV advertisements before 9 PM, effective from
October 2025.
September 25, 2024
VIEW ALL NEWS



LATEST PRESS RELEASES




Advancements in Cancer Treatment: Innovations and Breakthrough

2024-07-15
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Advancements in Cancer Treatment: Innovations and Breakthrough

Advancements in cancer treatment have transformed the landscape of oncology,
offering new hope and improved outcomes for patients facing this complex
disease. This article explores recent innovations and breakthroughs in cancer
treatment, highlighting how these advancements are reshaping oncology practices
and improving patient care.

Precision Medicine: Tailoring Treatment to Individual Patients

One of the most significant advancements in cancer treatment is the shift
towards precision medicine. Precision medicine involves the customization of
treatment based on the unique genetic, molecular, and cellular characteristics
of each patient's cancer. This approach allows oncologists to select therapies
that are more likely to be effective and less toxic, leading to better outcomes
and reduced side effects.

Example: Targeted Therapies

Targeted therapies are drugs designed to target specific molecules or pathways
involved in the growth and survival of cancer cells. Examples include:


 * EGFR Inhibitors: Used in the treatment of certain types of lung cancer and
   colorectal cancer.
 * HER2 Inhibitors: Effective against HER2-positive breast cancer.
 * BRAF Inhibitors: Used for treating melanoma with BRAF mutations.

These therapies have shown remarkable efficacy in specific patient populations,
highlighting the importance of molecular profiling and personalized treatment
strategies.

Immunotherapy: Harnessing the Power of the Immune System

Another groundbreaking innovation in cancer treatment is immunotherapy, which
harnesses the body's immune system to fight cancer. Immunotherapy works by
enhancing immune responses or by removing barriers that prevent the immune
system from recognizing and attacking cancer cells.

Example: Checkpoint Inhibitors

Checkpoint inhibitors are a type of immunotherapy that blocks proteins called
checkpoints, which cancer cells use to evade immune detection. Drugs like
pembrolizumab (Keytruda) and nivolumab (Opdivo) have revolutionized the
treatment of various cancers, including melanoma, lung cancer, and kidney
cancer, leading to durable responses and improved survival rates in some
patients.

Advances in Surgery and Radiation Therapy

Surgical techniques and radiation therapy have also evolved significantly,
allowing for more precise and minimally invasive procedures. Advances such as
robotic surgery, image-guided radiation therapy (IGRT), and proton therapy have
improved treatment accuracy while reducing recovery times and minimizing damage
to surrounding healthy tissues.

Example: Robotic Surgery

Robotic-assisted surgery, such as the da Vinci Surgical System, enables surgeons
to perform complex procedures with enhanced precision and control. This
technology is used in the treatment of prostate cancer, colorectal cancer, and
other malignancies, offering patients faster recovery and improved outcomes.

Liquid Biopsies and Early Detection

The development of liquid biopsies represents a promising approach for early
cancer detection and monitoring treatment response. Liquid biopsies analyze
circulating tumor cells (CTCs), cell-free DNA (cfDNA), and other biomarkers in
the blood or other bodily fluids. These non-invasive tests provide valuable
information about tumor mutations, treatment resistance, and disease
progression, guiding treatment decisions and improving patient outcomes.

Example: Circulating Tumor DNA (ctDNA) Analysis

ctDNA analysis detects tumor-specific genetic alterations in blood samples,
offering real-time insights into cancer dynamics and response to therapy. This
technology is particularly valuable in monitoring minimal residual disease and
detecting early signs of recurrence.

Collaborative Research and Clinical Trials

Collaborative research initiatives and clinical trials play a crucial role in
driving innovation and validating new treatment approaches in oncology.
Multidisciplinary teams of researchers, clinicians, and pharmaceutical companies
work together to explore novel therapies, biomarkers, and treatment combinations
that may benefit cancer patients.

Conclusion

Advancements in cancer treatment, including precision medicine, immunotherapy,
advanced surgical techniques, and early detection methods, are revolutionizing
oncology and improving patient outcomes worldwide. These innovations represent
the culmination of decades of research, innovation, and collaboration within the
scientific and medical communities. As technology continues to evolve and our
understanding of cancer biology deepens, the future holds promise for even more
effective and personalized treatments, bringing hope to patients and families
affected by cancer.



Celebrating 100 Years of Peel's: A Century of Pure Honey Excellence

2024-05-30
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Celebrating 100 Years of Peel's: A Century of Pure Honey Excellence



MIDLANDS, SOUTH AFRICA - MAY 2024

Peel's, South Africa's oldest honey company, is proud to celebrate its
centennial anniversary. From humble beginnings in 1924, Peel's has grown into a
beloved household brand known for its unwavering commitment to quality and
heritage.




A JOURNEY THROUGH TIME


The Peel's story began with Jack Peel, a passionate beekeeper who started his
apiary as a hobby in the Midlands. Jack's love for bees and dedication to
producing pure honey soon found a growing customer base among friends and
neighbours. As demand soared, so did the number of his beehives. In 1956, Jack
met fellow beekeeper John Smith. Their shared enthusiasm for beekeeping led to a
fruitful partnership. After Jack's passing in 1959, John and his wife Faye
continued to build on Jack's legacy. They sold their honey products directly
from their car boot by the roadside, eventually constructing a charming wooden
kiosk that became a local landmark.




A LEGACY OF QUALITY AND COMMUNITY


Peel's has changed ownership over the years, each new custodian bringing fresh
ideas and energy while maintaining the brand's core values. Today, the Peel's
shop on the scenic Midlands Meander is a popular destination, with loyal
customers cherishing memories of visits, road trips, and the delicious taste of
Peel's honey. Our beekeeping operations have expanded significantly, with hives
across KwaZulu-Natal and the Free State. Peel's remains committed to supporting
small and medium-sized local beekeepers, ensuring our honey is 100% South
African and of the highest quality.




THE BENEFITS OF HONEY


As we celebrate this milestone, we also highlight the numerous benefits of honey
consumption. Honey is a natural sweetener and a source of antioxidants,
vitamins, and minerals. It has antibacterial and anti-inflammatory properties,
making it a valuable addition to a healthy diet. Whether enjoyed in tea or
coffee, spread on toast, or used in cooking and baking, honey's versatility and
health benefits are unparalleled.




LOOKING FORWARD


As we commemorate 100 years of excellence, we extend our deepest gratitude to
our customers, beekeepers, and everyone who has been part of the Peel?s journey.
Our dedication to producing pure, high-quality honey remains steadfast, and we
look forward to many more years of serving our community. Here's to the next
century of Peel's - let the journey continue!

Contact: Peel's Honey
Midlands Meander, South Africa
Phone: +27 (0) 33 330 0000
Email: sales@peelshoney.co.za
Shop Online: peels.co.za



Premier Verification

2023-02-08
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Premier Verification

We are proudly rated as a level 2 B-BBEE with 51% Black Female Ownership.

We are a SANAS Accredited Verification Agency and we perform verifications on
the DTIC Scorecard and on the majority of the Sectors Charters Scorecards.

We believe that B-BBEE should play a vital role in companies corporate
strategies to create economic growth in South Africa.

True and successful transformation is the key to long term success.





Tax Shop

2023-02-07
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Tax Shop



Income Tax Amendments leads to tax savings for Medical Practitioners

The South African tax landscape can be daunting to manage for business managers
and health care practitioners alike. What to pay, when to pay and how much to
pay all need to be done accurately and timeously to avoid penalties and interest
imposed willingly by SARS. As Benjamin Franklin stated in 1789, nothing can be
said to be certain, except death and taxes.

There are numerous changes to the tax regime on an annual basis, sometimes
impacting the general tax payer and other times impacting specific types of tax
payers. The most noticeable changes to the Income Tax Act in recent times now
allow health care practitioners to enjoy substantial savings on their Income Tax
liability of up to R100,000 every year. This can be achieved with minimal
changes to your current tax status. There is also VAT savings of R150,000 for an
initial twelve-month period available to current VAT payers.

These savings on Income Tax and VAT are exclusively available to health care
practitioners with their own private medical practice and a staff compliment.

Should you wish to learn more on these tax savings available to health care
practitioners, please email the author at walter.green@taxshop.co.za. Author ?
WT Green CA(SA)

Part of the national tax shop group www.taxshop.co.za



Medrisk

2022-10-20
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Medrisk



Medrisk is South Africa's leading independant medical malpractice consultants
with more than 15 years of combined expertise in advising, protecting, and
defending the healthcare community. Together with the expertise of our
underwriting partners, we would ensure that you would always have the best
possible protection.

We have solutions for all healthcare professionals as well as institutions and
have already saved our clients millions in premiums over the past few years.

We have a relentless emphasis on helping providers making it more affordable for
practitioners to be in a private practice, particularly high-risk specialists,
such as obstetricians, neurosurgeons as they are the ones who are more at risk-
hence some of them are paying absurdly high premiums.

We have recently added cyber insurance to our product offering as healthcare
professionals hold confidential patient information and are at risk for
cyberattacks.

Many healthcare professionals do not have malpractice insurance because they
don't understand the risk or they believe it is too expensive.

Medrisk now offers an affordable cyber insurance solution that will give
healthcare providers peace of mind that they are adequately covered.

With so many distractions health care professionals are faced with, our
commitment is to help healthcare providers and administrators focus on what
matters most, giving superior patient care. By partnering with us, no longer do
you need to stress about affordable malpractice and cyber insurance premiums.

In addition to the affordable premiums we provide you with, we continuously
would provide you with resources and educational material to help mitigate risk
and enhance patient care.

We have healthcare professionals in every part of South Africa who are happy
with our service and we welcome you to contact us to see how we could make a
difference in your practice.



A Complete End-To-End Solution for Healthcare Professionals

2021-06-24
×
A Complete End-To-End Solution for Healthcare Professionals


Trusted by over 3000 practices: We support all Medical Aids and COID Automated
Pathology Reports

Benefit Checker - Check member benefits in real time

Virtual Medical Claims - See what medical aid will pay

Specialized Claim Delivery - No internet, no problem

Practice Management Software

Tariff Coding / Pricing

Family Check / Member Validation - Validate members in real time

Electronic Remittance Advice

SMS

Calendar - Manage patient visits and more

Cloud - Online / Offline, work without internet

eRecoveries - Patient debt management




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