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    * Full Prescribing Information
    * Patient Information

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In this page special characters are used as Footnotes reference and respective
footnotes are present at the end of the main landmark

#1

prescribed medicine

for chronic hepatitis C (hep C)†



Have hep C?


CURE* IT.CRUSH IT.CONQUER IT.

In only 8 weeks with MAVYRET.

For those new to treatment.

Learn why it's important
to CRUSH hep C

*Cure means no hep C virus found in the blood 3 months after treatment ends.
Individual results may vary.

 †Based on data from IQVIA, week ending 1/12/18 to 10/28/22.



How soon would you want to start treating your hep C?

Within the next 6 months Unsure


RESOURCES ARE AVAILABLE TO HELP YOU UNDERSTAND THE COST OF MAVYRET AND YOUR
COVERAGE.

Understand cost and coverage




HERE’S MORE INFORMATION ABOUT HOW HEP C MAY DAMAGE THE LIVER OVER TIME.

Get hep C facts



Return to poll

"I looked forward to every day because I knew I was one step closer to being
CURED.*"

– Danny, CURED* with MAVYRET



“Getting CURED* of hepatitis C with MAVYRET was the final thing I needed to
resolve to move on.”

– Jules, CURED* with MAVYRET



“I want to share my story to help others with hep C. This is my experience
taking MAVYRET.”

– James, CURED* with MAVYRET



"I looked forward to every day because I knew I was one step closer to being
CURED.*"

– Danny, CURED* with MAVYRET



“Getting CURED* of hepatitis C with MAVYRET was the final thing I needed to
resolve to move on.”

– Jules, CURED* with MAVYRET



“I want to share my story to help others with hep C. This is my experience
taking MAVYRET.”

– James, CURED* with MAVYRET



"I looked forward to every day because I knew I was one step closer to being
CURED.*"

– Danny, CURED* with MAVYRET





“I took MAVYRET right before work.”

Read how to take MAVYRET

“Hear real stories about MAVYRET.”

Meet people CURED* with MAVYRET

“Medicaid covered my treatment. You may be covered, too.”

Understand MAVYRET costs


USE

MAVYRET is a prescription medicine used to treat adults and children 3 years of
age and older with chronic (lasting a long time) hepatitis C virus (hep C):

 * Genotypes (GT) 1, 2, 3, 4, 5 or 6 infection without cirrhosis or with
   compensated cirrhosis
 * Or GT 1 infection and have been previously treated with a regimen that
   contained a hep C NS5A inhibitor or an NS3/4A protease inhibitor, but not
   both.


IMPORTANT SAFETY INFORMATION

What is the most important information I should know about MAVYRET?

Hepatitis B virus (hep B) reactivation: Before starting treatment with MAVYRET,
your doctor will do blood tests to check for hep B infection. If you have ever
had hep B infection, hep B could become active again during or after treatment
for hep C with MAVYRET. Hep B that becomes active again (called reactivation)
may cause serious liver problems, including liver failure and death. Your doctor
will monitor you if you are at risk for hep B reactivation during treatment and
after you stop taking MAVYRET.

Do not take MAVYRET if you:

 * Have certain liver problems
 * Are taking the medicines atazanavir or rifampin

What should I tell my doctor before taking MAVYRET?

 * If you have had hep B infection, have liver problems other than hep C
   infection, have HIV-1 infection, have had a liver or a kidney transplant, and
   all other medical conditions.
 * If you are pregnant or plan to become pregnant, or if you are breastfeeding
   or plan to breastfeed. It is not known if MAVYRET will harm your unborn baby
   or pass into your breast milk. Talk to your doctor about the best way to feed
   your baby if you take MAVYRET.
 * About all the medicines you take, including prescription and over-the-counter
   medicines, vitamins, and herbal supplements. MAVYRET and other medicines may
   affect each other. This can cause you to have too much or not enough MAVYRET
   or other medicines in your body. This may affect the way MAVYRET or your
   other medicines work or may cause side effects.
 * Do not start taking a new medicine without telling your doctor. Your doctor
   can tell you if it is safe to take MAVYRET with other medicines.

What are the possible side effects of MAVYRET?

 * In people who had or have advanced liver problems before starting treatment
   with MAVYRET, there is a rare risk of worsening liver problems, liver
   failure, and death. Your doctor will check you for signs and symptoms of
   worsening liver problems during treatment with MAVYRET. Tell your doctor
   right away if you have any of the following: nausea; tiredness; yellowing of
   your skin or white part of your eyes; bleeding or bruising more easily than
   normal; confusion; dark, black, or bloody stool; loss of appetite; diarrhea;
   dark or brown (tea-colored) urine; swelling or pain on the upper right side
   of your stomach area (abdomen); sleepiness; vomiting of blood; or
   lightheadedness.
 * The most common side effects of MAVYRET are headache and tiredness.

These are not all the possible side effects of MAVYRET. Call your doctor for
medical advice about side effects.

This is the most important information to know about MAVYRET. For more
information, talk to your doctor or healthcare provider.

MAVYRET oral pellets are dispensed in unit-dose packets. Each packet contains 50
mg glecaprevir/20 mg pibrentasvir.

You are encouraged to report negative side effects of prescription drugs to the
FDA. Visit

www.fda.gov/medwatch

or call 1-800-FDA-1088.

Please see full Prescribing Information, including the Patient Information.

If you are having difficulty paying for your medicine, AbbVie may be able to
help. Visit AbbVie.com/myAbbVieAssist to learn more.

US-MAVY-220155


 * IMPORTANT SAFETY INFORMATION
 * FULL PRESCRIBING INFORMATION
 * PATIENT INFORMATION
 * FIND A HEALTHCARE PROFESSIONAL
 * COST & SAVINGS

 * ABBVIE
 * SITE MAP
 * Accessibility Statement
 * CONTACT US
 * TERMS OF USE
 * PRIVACY NOTICE
 * Cookies Settings
 * Your Privacy Choices

Legal Notices/Privacy Policy. Copyright 2023, AbbVie Inc., North Chicago,
Illinois, U.S.A. If you have any questions about AbbVie’s MAVYRET.com website
that have not been answered, click here. This website and the information
contained herein is intended for use by US residents only, is provided for
informational purposes only and is not intended to replace a discussion with a
healthcare provider. All decisions regarding patients must be made with a
healthcare provider and consider the unique characteristics of each patient.

© 2023 AbbVie. All rights reserved.
MAVYRET® and its design are registered trademarks of AbbVie Inc.
If you have any questions about this AbbVie Inc. website that have not been
answered, contact us.

US-MAVY-220333









YOU ARE LEAVING MAVYRET.COM

You are leaving the AbbVie website and connecting to a site that is not under
the control of AbbVie. AbbVie is not responsible for the contents of any such
site or any further links from such site. AbbVie is providing these links to you
only as a convenience and the inclusion of any link does not imply the
endorsement of the linked site by AbbVie. You should also be aware that the
linked site may be governed by its own set of terms and conditions and privacy
policy for which AbbVie has no responsibility.

Conversely, the presence of this link does not imply the linked site's
endorsement of MAVYRET.com or AbbVie.

Do you wish to leave this site?

Yes
No

US-MAVY-220333


USE

MAVYRET is a prescription medicine used to treat adults and children 3 years of
age and older with chronic (lasting a long time) hepatitis C virus (hep C):

 * Genotypes (GT) 1, 2, 3, 4, 5 or 6 infection without cirrhosis or with
   compensated cirrhosis
 * Or GT 1 infection and have been previously treated with a regimen that
   contained a hep C NS5A inhibitor or an NS3/4A protease inhibitor, but not
   both.


IMPORTANT SAFETY INFORMATION

What is the most important information I should know about MAVYRET?

Hepatitis B virus (hep B) reactivation: Before starting treatment with MAVYRET,
your doctor will do blood tests to check for hep B infection. If you have ever
had hep B infection, hep B could become active again during or after treatment
for hep C with MAVYRET. Hep B that becomes active again (called reactivation)
may cause serious liver problems, including liver failure and death. Your doctor
will monitor you if you are at risk for hep B reactivation during treatment and
after you stop taking MAVYRET.

Do not take MAVYRET if you:

 * Have certain liver problems
 * Are taking the medicines atazanavir or rifampin

What should I tell my doctor before taking MAVYRET?

 * If you have had hep B infection, have liver problems other than hep C
   infection, have HIV-1 infection, have had a liver or a kidney transplant, and
   all other medical conditions.
 * If you are pregnant or plan to become pregnant, or if you are breastfeeding
   or plan to breastfeed. It is not known if MAVYRET will harm your unborn baby
   or pass into your breast milk. Talk to your doctor about the best way to feed
   your baby if you take MAVYRET.
 * About all the medicines you take, including prescription and over-the-counter
   medicines, vitamins, and herbal supplements. MAVYRET and other medicines may
   affect each other. This can cause you to have too much or not enough MAVYRET
   or other medicines in your body. This may affect the way MAVYRET or your
   other medicines work or may cause side effects.
 * Do not start taking a new medicine without telling your doctor. Your doctor
   can tell you if it is safe to take MAVYRET with other medicines.

What are the possible side effects of MAVYRET?

 * In people who had or have advanced liver problems before starting treatment
   with MAVYRET, there is a rare risk of worsening liver problems, liver
   failure, and death. Your doctor will check you for signs and symptoms of
   worsening liver problems during treatment with MAVYRET. Tell your doctor
   right away if you have any of the following: nausea; tiredness; yellowing of
   your skin or white part of your eyes; bleeding or bruising more easily than
   normal; confusion; dark, black, or bloody stool; loss of appetite; diarrhea;
   dark or brown (tea-colored) urine; swelling or pain on the upper right side
   of your stomach area (abdomen); sleepiness; vomiting of blood; or
   lightheadedness.
 * The most common side effects of MAVYRET are headache and tiredness.

These are not all the possible side effects of MAVYRET. Call your doctor for
medical advice about side effects.

This is the most important information to know about MAVYRET. For more
information, talk to your doctor or healthcare provider.

MAVYRET oral pellets are dispensed in unit-dose packets. Each packet contains 50
mg glecaprevir/20 mg pibrentasvir.

You are encouraged to report negative side effects of prescription drugs to the
FDA. Visit

www.fda.gov/medwatch

or call 1-800-FDA-1088.

Please see full Prescribing Information, including the Patient Information.

If you are having difficulty paying for your medicine, AbbVie may be able to
help. Visit AbbVie.com/myAbbVieAssist to learn more.

US-MAVY-220155


ARE YOU A HEALTHCARE PROFESSIONAL?

The information contained in this site is intended for U.S. healthcare
professionals.

By clicking “Yes” below, you certify that you are a licensed healthcare
professional.

Yes
No

US-MAVY-220333


YOU ARE LEAVING MAVYRET.COM

You are leaving the AbbVie website and connecting to a site that is not under
the control of AbbVie. AbbVie is not responsible for the contents of any such
site or any further links from such site. AbbVie is providing these links to you
only as a convenience and the inclusion of any link does not imply the
endorsement of the linked site by AbbVie. You should also be aware that the
linked site may be governed by its own set of terms and conditions and privacy
policy for which AbbVie has no responsibility.

Conversely, the presence of this link does not imply the linked site's
endorsement of MAVYRET.com or AbbVie.

Do you wish to leave this site?

 

Yes
No

US-MAVY-220333






USE

MAVYRET is a prescription medicine used to treat adults and children 3 years of
age and older with chronic (lasting a long time) hepatitis C virus (hep C):

 * Genotypes (GT) 1, 2, 3, 4, 5 or 6 infection without cirrhosis or with
   compensated

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about MAVYRET?

Hepatitis B virus (hep B) reactivation: Before starting treatment with MAVYRET,
your doctor will do blood tests to check for hep B infection. If you have ever
had hep B infection, hep B could become active again during or after treatment
for hep C with MAVYRET. Hep B that becomes active again (called reactivation)
may cause serious liver

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about MAVYRET?

Hepatitis B virus (hep B) reactivation: Before starting treatment with MAVYRET,
your doctor will do

USE

MAVYRET is a prescription medicine used to treat adults and children 3 years of
age and older with chronic (lasting a long time) hepatitis C virus (hep C):

 * Genotypes (GT) 1, 2, 3, 4, 5 or 6 infection without cirrhosis or with
   compensated

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about MAVYRET?

Hepatitis B virus (hep B) reactivation: Before starting treatment with MAVYRET,
your doctor will do blood tests to check for hep B infection. If you have ever
had hep B infection, hep B could become active again during or after treatment
for hep C with MAVYRET. Hep B that becomes active again (called reactivation)
may cause serious liver

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about MAVYRET?

Hepatitis B virus (hep B) reactivation: Before starting treatment with MAVYRET,
your doctor will do


USE

MAVYRET is a prescription medicine used to treat adults and children 3 years of
age and older with chronic (lasting a long time) hepatitis C virus (hep C):

 * Genotypes (GT) 1, 2, 3, 4, 5 or 6 infection without cirrhosis or with
   compensated cirrhosis
 * Or GT 1 infection and have been previously treated with a regimen that
   contained a hep C NS5A inhibitor or an NS3/4A protease inhibitor, but not
   both.


IMPORTANT SAFETY INFORMATION

What is the most important information I should know about MAVYRET?

Hepatitis B virus (hep B) reactivation: Before starting treatment with MAVYRET,
your doctor will do blood tests to check for hep B infection. If you have ever
had hep B infection, hep B could become active again during or after treatment
for hep C with MAVYRET. Hep B that becomes active again (called reactivation)
may cause serious liver problems, including liver failure and death. Your doctor
will monitor you if you are at risk for hep B reactivation during treatment and
after you stop taking MAVYRET.

Do not take MAVYRET if you:

 * Have certain liver problems
 * Are taking the medicines atazanavir or rifampin

What should I tell my doctor before taking MAVYRET?

 * If you have had hep B infection, have liver problems other than hep C
   infection, have HIV-1 infection, have had a liver or a kidney transplant, and
   all other medical conditions.
 * If you are pregnant or plan to become pregnant, or if you are breastfeeding
   or plan to breastfeed. It is not known if MAVYRET will harm your unborn baby
   or pass into your breast milk. Talk to your doctor about the best way to feed
   your baby if you take MAVYRET.
 * About all the medicines you take, including prescription and over-the-counter
   medicines, vitamins, and herbal supplements. MAVYRET and other medicines may
   affect each other. This can cause you to have too much or not enough MAVYRET
   or other medicines in your body. This may affect the way MAVYRET or your
   other medicines work or may cause side effects.
 * Do not start taking a new medicine without telling your doctor. Your doctor
   can tell you if it is safe to take MAVYRET with other medicines.

What are the possible side effects of MAVYRET?

 * In people who had or have advanced liver problems before starting treatment
   with MAVYRET, there is a rare risk of worsening liver problems, liver
   failure, and death. Your doctor will check you for signs and symptoms of
   worsening liver problems during treatment with MAVYRET. Tell your doctor
   right away if you have any of the following: nausea; tiredness; yellowing of
   your skin or white part of your eyes; bleeding or bruising more easily than
   normal; confusion; dark, black, or bloody stool; loss of appetite; diarrhea;
   dark or brown (tea-colored) urine; swelling or pain on the upper right side
   of your stomach area (abdomen); sleepiness; vomiting of blood; or
   lightheadedness.
 * The most common side effects of MAVYRET are headache and tiredness.

These are not all the possible side effects of MAVYRET. Call your doctor for
medical advice about side effects.

This is the most important information to know about MAVYRET. For more
information, talk to your doctor or healthcare provider.

MAVYRET oral pellets are dispensed in unit-dose packets. Each packet contains 50
mg glecaprevir/20 mg pibrentasvir.

You are encouraged to report negative side effects of prescription drugs to the
FDA. Visit

www.fda.gov/medwatch

or call 1-800-FDA-1088.

Please see full Prescribing Information, including the Patient Information.

If you are having difficulty paying for your medicine, AbbVie may be able to
help. Visit AbbVie.com/myAbbVieAssist to learn more.

US-MAVY-220155




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