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PIMPLE IN MOUTH: COMMON CAUSES AND BEST TREATMENTS

Medically reviewed by Alana Biggers, M.D., MPH — By Zia Sherrell, MPH on March
13, 2023
 * Mouth sores
 * Symptoms
 * Canker sores
 * Cold sores
 * Mucoceles
 * Torus palatinus
 * Candidiasis
 * Hand, foot, and mouth disease
 * Epstein pearls
 * Hyperdontia
 * Squamous papilloma
 * Oral cancer
 * When to see a doctor

Mouth sores are very common and tend to be harmless. However, mouth pimples can
also indicate a chronic condition that needs prompt medical attention. Talk to
your doctor if you suspect your mouth sore is a sign of something serious.

Got a pimple, blister, ulcer, or sore in your mouth? In most cases, mouth sores
aren’t a major cause for concern. But since they can indicate a more serious
health condition – like oral cancer or a sexually transmitted infection (STI) –
it’s important to understand your specific symptoms.

Here’s a detailed overview of the different causes of mouth sores, plus the best
treatments for all.

Share on Pinterest


WHAT ARE MOUTH SORES?

Mouth sores are, er, sores in your mouth! These lesions can take many guises,
from tiny blisters to large open sores, practically painless to seriously
uncomfortable.

You can develop a mouth sore anywhere on the soft tissues of your mouth,
including the:

 * lips
 * gums
 * tongue
 * roof of your mouth
 * floor of your mouth
 * inside of the cheeks

Some types of mouth sores, like canker sores, disappear on their own within a
couple of weeks. Others, like candidiasis, aren’t particularly alarming but
might indicate an underlying health concern.

At the far end of the mouth sore severity spectrum is oral cancer. No, it’s not
a likely culprit, but if your mouth sore won’t leave you alone, go see your
doctor and find out why.

Mouth ulcers and sores have a load of possible causes. Some are due to a
short-term cause like:

 * Canker sores, which are random mouth ulcers with many triggers
 * Cold sores caused by the herpes simplex virus
 * Trauma caused by physical damage like biting your tongue or abrasions from
   braces
 * Allergies or reactions to ingredients in food, toothpaste, or medications
 * Stress due to your lifestyle, job, or relationship woes
 * Infectious mononucleosis (mono, an infection by the Epstein-Barr virus
 * Oral thrush, a fungal infection caused by an overgrowth of the Candida yeast
 * Hand, foot, and mouth disease caused by the Coxsackie virus
 * Leukoplakia, or white patches caused by repeated injury or irritation

On the flip side, your mouth sore could be due to a long-term cause, like:

 * Celiac disease is a condition where your immune system attacks you when you
   eat gluten.
 * Nutritional deficiencies shortfalls in vitamins and minerals like iron,
   folate, vitamin B6 and B12
 * HIV/AIDS can weaken your immune system
 * Oral cancer is fairly rare and can cause mouth sores.
 * Pemphigus vulgaris is a rare long-term condition where your immune system
   attacks healthy cells, causing blisters on the skin and mouth

As you can see, there are oodles of causes. So if your mouth zit won’t go away,
it’s time to book an appointment with your doctor and find out what’s up.


WHAT DO MOUTH SORES FEEL LIKE?

Mouth sores may look and feel different depending on the underlying cause.
Here’s what to look out for:

 * Pain. They may be seriously painful, slightly uncomfortable, or completely
   painless.
 * Color. They can appear in a rainbow of colors, from the same as the
   surrounding tissue to white or yellow and gray to red or purple.
 * Size. They can range in size from a tiny dot to several centimeters wide.
 * Texture. Smooth, raised, bumpy, lumpy, velvety, or like a raspberry. There
   are multiple variations.
 * Location. They can appear on any part of the mouth, from the inner cheeks and
   tongue to the lips and gums and the roof or floor of the mouth.
 * Sensation. You may feel tingling, burning, or itching at the sore’s location.



CANKER SORES

If your mouth sores are small, round, open, and seriously painful, canker may be
the culprit. These white, yellow, or pale pink lesions aren’t contagious, but
they can make it tricky to eat or speak.

Possible causes of canker sores, also called aphthous ulcers, can range from
stress to genetics. Other contributing factors include minor injuries, certain
foods or drinks, and allergic reactions.

Most minor canker sores go away on their own and heal within a couple of weeks.
In the meantime, over-the-counter (OTC) pain relievers and numbing gels can help
with the discomfort and avoid irritating alcohol-based mouthwash.



COLD SORES

Annoying AF blister lingering on your lips? Tingling and burning? You may have a
cold sore. These clusters of red, fluid-filled bumps are caused by the herpes
simplex virus and are highly contagious.

Unfortunately, there’s no cure for a cold sore. But the good news is that it
will probably go away on its own within two weeks after appearing. While you
wait, ice packs, OTC pain relievers, and antiviral creams can ease symptoms and
speed recovery.

MUCOCELES

An oral mucocele is a harmless and painless mucus-filled cyst that’s typically
smooth and round. They can crop up if you bite your lip or inner cheek, or if
the skin experiences some other minor trauma. The injury can damage or block a
salivary gland, so saliva builds up and forms a cyst.

You usually don’t need treatment because these mouth sores go away on their own.
by themselves. But your doc can remove any that cause discomfort.


TORUS PALATINUS

Not all mouth sores involve soft tissue. Torus palatinus is a harmless, bony
overgrowth that can show up on the roof of your mouth. It can be a single, large
bump or a few small ones clustered together.

You shouldn’t experience pain or other symptoms with most minor torus, so
treatment is usually unnecessary. But if it’s large or causing discomfort, your
doc can remove it with a small procedure.

Experts are unsure why some folks develop torus palatinus, but it may involve
your family history.


CANDIDIASIS

Candidiasis, or oral thrush, is a yeast infection that often affects newborns
and peeps with an underlying condition that weakens their immune systems.
Symptoms may include creamy white patches inside the mouth, difficulty
swallowing, soreness, and a red rash on the tongue and roof of the mouth.

If you have oral thrush, there’s a good chance it won’t go away on its own. If
you develop candidiasis, your doctor can prescribe antifungal meds for 7 to 14
days.


HAND, FOOT, AND MOUTH DISEASE

Hand, foot, and mouth disease (HFMD) is caused by coxsackievirus. This
charmingly named virus shows up unannounced and wreaks havoc in your mouth by
producing painful blisters and red bumps, not to mention fever and body aches.
As you may guess by the name, HFMD can affect your hands and feet too.

This virus is more common in young kids but can affect anyone. If you’re
suffering, you’ll be glad to know HFMD tends to go away in a week, but rest,
fluids, and pain relievers can help relieve the symptoms.

EPSTEIN PEARLS

Epstein pearls are common in newborns. These small, harmless cysts usually go
away within a few weeks without causing any problems.

If you spot these on your baby, don’t fret. Just monitor them and check in with
your healthcare team if you have any questions or concerns.


HYPERDONTIA

Hyperdontia is the technical term for having additional teeth. If you notice a
painful bump on the roof of your mouth or behind your other teeth, it might be
an extra player trying to wrestle to the surface.

Depending on where they are and how many, some teeth may need to be removed
because they can interfere with your bite. Consult with your dentist to figure
out a plan.

SQUAMOUS PAPILLOMA

When mouth sores look like bumps or warts with a bumpy, cauliflower-like
texture, it could be squamous papilloma. The culprit here is the human
papillomavirus (HPV), which causes genital warts.

These growths are non-cancerous and painless. And although they’re fugly, they
often go away without treatment. But remember folks, these


ORAL CANCER

Rarely, what looks like a sore or zit inside your mouth turns out to be oral or
mouth cancer. Symptoms can include white, gray, or bright red sores or bumps
that are oddly shaped, may bleed, and don’t heal. They can appear anywhere
inside the mouth, including the lips, cheeks, gums, or tongue. The sores may be
painful.

A condition called leukoplakia increases your risk of oral cancer. These
thickened, white patches can’t be scraped off. It seems that chronic irritation
from tobacco is the main culprit in its development.

If you suspect oral cancer, see your doc stat. Early detection is key for
successful treatment and outlook. Surgery is often the first treatment for these
cancers and may be followed by radiation or chemotherapy.

WHEN TO SEE A HEALTHCARE PROVIDER

Any mouth ulcers, sores, or bumps that don’t improve within a couple of weeks
deserve an evaluation by your healthcare provider. Likewise, if you notice the
lesions worsening, with increased swelling, bleeding, or changes to skin texture
or color, make that appointment pronto.

Bumps and sores inside your mouth are usually harmless, but your doc can take a
look, assess the situation, and recommend the best course of action. It’s always
better to be safe than sorry!


BOTTOM LINE

Lumps, bumps, and sores inside your mouth might be related to a virus, fungal
infection, injury, or something else. Usually, they don’t require extensive
treatment and often go away on their own.

But if they persist or worsen, or you’re concerned, see your healthcare
provider. They can evaluate the situation and offer guidance on the best
treatment plan.



Last medically reviewed on March 13, 2023

7 sourcesexpanded

 * Candida infections of the mouth, throat, and esophagus. (2021).
   cdc.gov/fungal/diseases/candidiasis/thrush/index.html
 * Canker sores. (2019).
   ncbi.nlm.nih.gov/books/NBK546250
 * Guerra AM, et al. (2022). Hand foot and mouth disease.
   ncbi.nlm.nih.gov/books/NBK431082
 * Plewa MC, et al. (2022). Aphthous Stomatitis.
   ncbi.nlm.nih.gov/books/NBK431059/#article-17766.s9
 * Saleh D, et al. (2022). Herpes Simplex Type 1.
   ncbi.nlm.nih.gov/books/NBK482197
 * El Sergani AM, et al. (2020). Prevalence of Torus Palatinus and association
   with dental arch shape in a multi-ethnic cohort.
   ncbi.nlm.nih.gov/pmc/articles/PMC7674192/
 * Surgery for oral and oropharyngeal cancer. (2021).
   cancer.org/cancer/oral-cavity-and-oropharyngeal-cancer/treating/surgery.html

FEEDBACK:

Medically reviewed by Alana Biggers, M.D., MPH — By Zia Sherrell, MPH on March
13, 2023




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