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ABOUT US


CAN·FITE BIOPHARMA

is an Israeli biopharmaceutical company with fully integrated pharmaceutical
discovery and clinical development capabilities.


The Company has an advanced pipeline of proprietary drug candidates in Phase II
and Phase III clinical development which address inflammatory, liver and
metabolic diseases.


Can-Fite's platform technology utilizes the Gi protein associated A3 adenosine
receptor (A3AR) as a therapeutic target. A3AR is highly expressed in
inflammatory, cancer and other pathological body cells whereas low expression is
found in normal cells, suggesting that the receptor could be a unique target for
pharmacological intervention.


The Company's compounds bind with nM affinity to the A3AR and initiate
de-regulation of the NF-kB and the Wnt signal transduction pathways resulting in
anti-inflammatory and anti-cancer effects.

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PIPELINE



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CORPORATE PARTNERSHIPS

Piclidenoson for the treatment of psoriasis has been out-licensed to Cipher
Pharmaceuticals in Canada, to Gebro Pharma GmbH in Spain, Switzerland & Austria,
Kyongbo Pharm in Korea, to CMS  in China, Taiwan, Hong Kong and Macao.

Namodenoson for the treatment of Liver Cancer and NASH has been out-licensed  to
Chong Kun Dang (CKD) Pharmaceutical in Korea and to CMS in China.

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