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PRODUCTS

 * Technologies
   * Imaging Mass Cytometry
   * Mass Cytometry
   * Microfluidics
 * Instruments
   * CyTOF XT
   * Hyperion XTi Imaging System
   * Biomark X9 System for High-Throughput Genomics
 * Kits, Reagents, & Accessories
   * Cytometry
   * Tissue Imaging
   * Genomics
 * Antibody and Panel Kit Selector
   * Imaging Mass Cytometry
   * Flow Cytometry by CyTOF
 * Software


SERVICES

 * Standard BioTools PRO Services
   * Product Care
   * Scientific Consultation & Training
   * Custom Services
 * Standard BioTools Discovery Lab
 * OEM Partnership
 * Tools
   * Custom Assay Design
   * Panel Designer


AREA OF INTEREST

 * AgBio
   * Livestock Health and Management – Sustainable Agriculture
   * Plant and Seed Research – Sustainable Agriculture
   * Fisheries and Aquaculture Research – Sustainable Agriculture
 * Biomarker Discovery
   * Biomarker Discovery with Imaging Mass Cytometry
 * Cell Segmentation
   * Cell Segmentation with Imaging Mass Cytometry
 * COVID-19
 * Genomics Analysis
   * NGS Library Prep
   * PCR Applications
 * Immune Profiling 
   * Human Maxpar Direct Immune Profiling System
   * Maxpar OnDemand Mouse Immune Profiling Panel Kit
 * Infectious Disease
   * Infectious Disease with Imaging Mass Cytometry
   * Infectious Disease with Mass Cytometry
 * Immuno-Oncology
   * Immuno-Oncology with Imaging Mass Cytometry
   * Immuno-Oncology with Mass Cytometry
   * Immuno-Oncology with Microfluidics
 * Neuroscience
   * Neuroscience with Imaging Mass Cytometry
 * Pharmacogenomics (PGx)
   * PGx with Microfluidics
 * Public Health
 * Sample ID and Quality Control
   * Sample ID and Quality Control with Microfluidics
 * Single-Cell Analysis
   * Single-Cell Analysis with Microfluidics
 * Spatial Biology
   * Spatial Biology with Imaging Mass Cytometry
 * Translational and Clinical Research
   * Clinical Research with Mass Cytometry
 * RNA Detection with Imaging Mass Cytometry
   * Co-Detection of RNA and Protein


RESOURCES

 * Customer Stories
   * Customer Stories: Imaging Mass Cytometry
   * Customer Stories: Mass Cytometry
   * Customer Stories: Microfluidics
 * Events
 * Blog
 * Videos
   * Featured Webinar and Event Videos
 * Safety Data Sheets
 * Spatial Biology Learning Center
 * Publications
 * Panel Design


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   * Product Care
   * Scientific Consultation and Training
   * Custom Services
 * Instrument Support
   * Access Array System
   * Biomark and EP1 Systems
   * Biomark X System
   * C1 System
   * CyTOF XT System
   * Helios and CyTOF 2 Systems
   * Hyperion and Hyperion+ Imaging Systems
   * Hyperion XTi Imaging System
   * Juno System
   * Polaris System
   * Biomark X9 System for High-Throughput Genomics
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Area of Interest Immune Profiling  Human Maxpar Direct Immune Profiling System


IMMUNE PROFILING


MAXPAR DIRECT IMMUNE PROFILING ASSAY AND MAXPAR PATHSETTER SOFTWARE

Identify major circulating immune cell types in human whole blood or PBMC
samples with the validated, dry-format Maxpar® Direct™ Immune Profiling Assay™.

This robust immunophenotyping assay provides clinicians with an
easy-to-implement solution for routine and reproducible sample collection to
capture the highly individual nature of immune response.

Now available in two sizes, a 25-test kit and 5-test kit format.

Order now


Overview Workflow Data Analysis Customization Resources Contact


OVERVIEW

Standardize immune monitoring studies

A simple single-tube workflow with automated analysis minimizes variability and
ensures high reproducibility of multiparameter data.




PROVEN PERFORMANCE AND REPRODUCIBILITY

Clinical and translational research demands reproducible and reliable immune
profiling, especially when samples are processed and analyzed by different
technicians or at different study sites1,2. The reproducibility of the Maxpar
Direct Immune Profiling System has been demonstrated run-to-run and
site-to-site.

See white paper


WORKFLOW

Learn how the single-tube assay speeds up sample collection to insights.

 
 
 
 
 

Click for sound





2:44











IDEAL FOR MULTICENTER OR LONGITUDINAL STUDIES


STAIN, FREEZE, SHIP

Unlike fluorescent tags that are light-sensitive, metal tags can withstand harsh
staining protocols and storage conditions, providing greater stability when
freezing or shipping samples.

See application note


STANDARDIZED SAMPLE COLLECTION

Maintain sample integrity between collection and processing by stabilizing whole
blood with preservation reagents, even at room temperature.

See poster data


DATA ANALYSIS

Actionable insights with rapid data

Maxpar® Pathsetter™ software is a fully automated reporting and data analysis
solution that automatically identifies 37 immune cell types in FCS files from
samples processed with the Maxpar Direct Immune Profiling Assay.

Learn more




EXPANDING AND CUSTOMIZING

Easily build on the Maxpar Direct™ backbone panel with individual antibodies or
Expansion Panels, designed to enable deeper profiling of specific immune cell
subsets that are relevant in immune-mediated disease, such as infectious
disease, cancer, autoimmunity or allergy.

9 EXPANSION PANELS

--------------------------------------------------------------------------------

 * Surface profiles
 * Cell proliferation
 * Cell exhaustion
 * Apoptosis
 * Metabolism
 * Phosphoproteins
 * Cytokine production
 * Transcription factors

Explore panels



APPLICATION NOTE

--------------------------------------------------------------------------------

Building a 47-marker flow cytometry panel to explore antigen-specific immune
responses.  Download application note

SCIENTIFIC POSTER

--------------------------------------------------------------------------------

A high-parameter mass cytometry panel for the functional characterization of CAR
T cells.  Download poster


PRODUCTS

Related products that expand the core, backbone assay.




MAXPAR® DIRECT™ T CELL ACTIVATION EXPANSION PANEL


THE MAXPAR® DIRECT™ T CELL ACTIVATION EXPANSION PANEL ENA…

Learn more

MAXPAR® DIRECT™ MYELOID AND LYMPHOID ACTIVATION EXPANSION PANEL


THE MAXPAR® DIRECT™ MYELOID AND LYMPHOID ACTIVATION EXPAN…

Learn more

MAXPAR® DIRECT™ NK CELL EXPANSION PANEL 1


THE MAXPAR® DIRECT™ NK CELL EXPANSION PANEL 1 ENABLES DEEP…

Learn more

MAXPAR® DIRECT™ MYELOID AND B CELL EXPANSION PANEL 1


MAXPAR® DIRECT™ MYELOID AND B CELL EXPANSION PANEL 1 ENABLES D…

Learn more

MAXPAR® DIRECT™ T-CELL EXPANSION PANEL 2


MAXPAR® DIRECT™ T CELL EXPANSION PANEL 2 ENABLES INVES…

Learn more

RESOURCES

Publications

Rouphael, N. et al. “Immunophenotyping assessment in a COVID-19 cohort (IMPACC):
A prospective longitudinal study.” Science Immunology 6 (2021): eabf3733
Bagwell, C.B. et al. “Multi-site reproducibility of a human immunophenotyping
assay in whole blood and peripheral blood mononuclear cells preparations using
CyTOF® technology coupled with Maxpar® Pathsetter™, an automated data analysis
system.” Cytometry Part B Clinical Cytometry 98 (2020): 146–160

User guides

Maxpar Direct Immune Profiling Assay Cell Staining and Data Acquisition User
Guide | 400286
Antibody Selection and Optimization: Customize the Maxpar Direct Immune
Profiling Assay User Guide | FLDM-00229
Method Develop: Customize the Maxpar Direct Immune Profiling Assay User Guide |
FLDM-00151

Technical documents

Approach to Bivariate Analysis of Data Acquired Using the Maxpar Direct Immune
Profiling Assay Technical Note | 400248
Impact of Cryopreservation on Performance of the Maxpar Direct Immune Profiling
System Application Note | FLDM-00089
Technical Data Sheet: Maxpar Direct Immune Profiling Assay, 30 Marker—25 Tests |
PRD036

Quick references

Maxpar Pathsetter: Analyze Data in Method Run Mode Quick Reference | 400297


RELATED BLOG POSTS

--------------------------------------------------------------------------------

 * Bringing the CyTOF advantage to CAR cell therapy research
 * Using high-parameter flow cytometry and tissue imaging to drive cardiology
   insights
 * Trillions of cells, hundreds of cell types, one collaborative effort
 * Five reasons to go beyond the limits of fluorescence with CyTOF technology
 * What does high-parameter cytometry really mean?


DON’T HAVE A CYTOF SYSTEM? WE CAN HELP!

Simply stain and ship samples to us. Get raw and analyzed data results within 72
hours.

Get in touch now



Unless explicitly and expressly stated otherwise, all products are provided for
Research Use Only, not for use in diagnostic procedures. Find more information
here.


CONNECT WITH US TO DISCOVER EVEN MORE.

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