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Testosterone replacement therapy


THE UK'S HIGHEST RATED TRT CLINIC

Top doctors, fast, convenient diagnosis, and the highest-rated testosterone
replacement therapy treatments from the comfort of your home.

Find out moreOrder a blood test
90%
of patients reported improvement in symptoms within 3 months
Ali, 34
Improved sex drive
Better sleep
90%
of patients saw life-changing improvements after 3 months
87%
of patients saw an improvement in their Libido after 6 months
+166%
improvement in patients' libido after 6 months
79%
of patients saw an improvement in their enjoyment of life after 6 months
+92%
improvement in patients' enjoyment of life after 6 months
Plus
many more benefits to get men back to their best


TrustScore 4.6/5 • 675 reviews


MANUAL TRT: EXPLAINED




WHAT IS TRT?

TRT is used to treat men with low testosterone levels, which can cause a range
of life-debilitating symptoms. It works by supplementing the hormone, helping
restore you to optimal body functions and overall well-being.



HOW DOES IT WORK?

TRT can be administered through various methods, including injections, gels and
creams. Our expert, best-in-class TRT clinicians will advise based on your needs
and preferences.



WHY MANUAL TRT?

Top doctors and world-class treatment at your fingertips - 9/10 patients see
life-changing results after just 3 months on treatment. Join the 7000+ men
who've transformed their lives with our world-leading treatment.


TrustScore 4.6/5 • 2,458 reviews

AS SEEN IN




THE HORMONE THAT’S HOLDING MEN BACK

Dr. Chris Airey, TRT Expert


1 IN 4 MEN SUFFER FROM LOW TESTOSTERONE¹

After the age of 40, testosterone levels start to decline by 1 to 2% on average
each year.²


90% OF MEN IN THE UK REMAIN UNDIAGNOSED³

Too many men are suffering from the life-altering symptoms of this
under-diagnosed condition.


LOW-T SYMPTOMS CAN TAKE THE JOY OUT OF LIFE

Low mood/anxiety

Low sex drive

Low muscle mass

Lack of focus

Low energy

Weight gain

Erectile dysfunction

Poor sleep quality

CITATIONS

¹ The Journal of Clinical Endocrinology & Metabolism, Volume 92, Issue 11, 1
November 2007, Pages 4241–4247
² Generational decline in testosterone levels observed
³ Testosterone deficiency in adults and corresponding treatment patterns across
the globe.

Check your symptomsLearn more about symptoms


DO YOU EXPERIENCE THESE SYMPTOMS?

Answer 10 quick questions to assess if low testosterone could be holding you
back.

Take the quiz


WITH TREATMENT YOU FEEL LIKE YOURSELF AGAIN

We’ve helped thousands of patients up their T-levels and transform their lives.
Our patients and their loved ones really noticed the results.


90%
of patients were satisfied with the treatment they received
+239%
average increase in Total Testosterone levels among patients over 3 months
+143%
‍improvement in energy levels after 3 months
+80%
improvement in patients' strength of erections after 6 months
+103%
improvement in physical ability after 6 months
+76%
improvement in patients' perceived happiness after 6 months

CITATIONS

Based on data on MANUAL clinical care data of over 2000 patients over the last
18 months


CLINICALLY PROVEN TREATMENT

Dr. Chris Airey, TRT Expert


We’ll help you get your testosterone levels back within a normal, healthy range.
Our TRT service has research-backed benefits to your health and wellbeing. The
results can be life-changing.

Better Mood


Look forward to more good days. Studies show that patients feel more energetic,
friendlier, less irritable and generally in a better mood after starting TRT.¹

Higher Sex Drive


Testosterone can help you get your mojo back. Numerous studies show that
increasing testosterone levels can enhance sex drive, improve erectile function
and increase overall sexual satisfaction.²

Increased Muscle


Testosterone has a bit of a reputation for building muscle and strength. Studies
show that increasing testosterone levels stimulates muscle protein synthesis and
enhances muscle mass.³

Better Sleep


Say goodnight to insomnia and look forward to sleeping soundly. Studies show
that patients who had testosterone replacement therapy reported significant
improvements in their sleep quality.⁴

Improved Memory


Testosterone can help you feel sharper and boost your memory. Studies show that
increasing testosterone levels can significantly improve overall cognitive
function in older men with low-T.⁵

CITATIONS

¹ Testosterone and Mood Improvement

2 Testosterone and Sexual Function

3 https://pubmed.ncbi.nlm.nih.gov/8855787/

4 Testosterone and Sleep Quality

5 Testosterone and Cognitive Function

1
Today
At-home Testosterone test

Start with a simple at-home finger-prick blood test which measures your total
and free testosterone levels.

Testosterone & Free Testosterone checked

Easy at-home finger-prick collection

Expert validated report

Analysed at UKAS certified laboratories
Get started for £33.95

2 weeks
Enhanced Testosterone test

A comprehensive venous blood test is needed to confirm the initial result, learn
more about your health, and assess whether it’s safe to start treatment.

Venous collection by a nurse

Checks liver, kidney & PSA levels to make sure you’re suitable for treatment

Analysed at UKAS certified laboratories
2
Within 4 weeks
Speak to a specialist Doctor

Discuss your blood test results, symptoms, medical history, treatment options
(including costs), and monitoring process with an expert TRT doctor.

Video consultation

Private and confidential

Qualified TRT experts

Analysed at UKAS certified laboratories
3
4 weeks
Start your treatment

Your doctor will design a personalised treatment plan that’s tailored to your
lifestyle. It may include medication, lifestyle advice or supplements.

Analysed at UKAS certified laboratories
4
On going
Testosterone monitoring and plan adjustments

We’ll test your blood at 6 weeks, 3 months, 6 months, and 12 months after to
allow your doctor to effectively monitor your progress and make any adjustments.

Analysed at UKAS certified laboratories
5

Our pricing
Take a closer look at our pricing structure to understand the cost of your
customised treatment plan.
Learn about pricing
THE PROCESS
THE PROCESS


HOW TO START TREATMENT

Get Started


A TREATMENT PLAN TAILORED
FOR YOU

As part of our TRT service, you’ll receive a comprehensive diagnosis and a
bespoke treatment plan that may include medication, lifestyle advice or
supplements.

Learn about TRT treatments
Injectable
Effectiveness

High

Format

Injections two or three times weekly for most patients

Results in

1-3 weeks

Oral
Effectiveness

Moderate

Format

Tablet taken once daily
‍

Results in

3-8 weeks

Topical
Effectiveness

Individual

Format

Apply to the shoulders or arms once a day

Results in

1-6 weeks


LED BY TRT EXPERTS

“We offer the most effective protocols in formats to suit your preference”

Learn about TRT treatments


SPECIALIST CARE ON YOUR TERMS

What you get
Manual
NHS
Convenient & online
Quick diagnosis & treatment
Doctors who specialise in TRT
Gold-standard treatment plans
Monitoring & treatment adjustment

Team


MEET OUR TRT EXPERTS

We have the UK’s leading TRT experts on board, so you know you’re in good hands.




DR. JEFF FOSTER

Medical Director of Men's Health
Read Bio


DR KAPIL SAVANIA


TRT Medical Expert
Read Bio


DR. IMAD MEKHAIL

TRT Medical Expert
Read Bio


DR. MANDEEP SANDHU

TRT Medical Expert
Read Bio


YOUR QUESTIONS ANSWERED

Our team has a lifetime’s worth of expertise and experience between them.
They’re on hand to answer all of your questions at every stage of your journey.

View all
About TRT
Symptoms
How it works

5 common symptoms of low testosterone
Dr David Huang, Deputy Medical Director
What are the potential benefits of TRT?
Dr Sheliza Darvesh, GP Clinical Lead
What type of people are on TRT?
‍
Dr. Mandeep Sandhu, TRT Specialist Doctor
Is there a discount?
‍
Dr Kapil Savania, TRT Specialist Doctor
Can I speak to someone about TRT?
Dr. Vivek Ramamoorthy, TRT Specialist Doctor
Is it legal to purchase TRT online?
Dr Sheliza Darvesh, GP Clinical Lead

FAQ


TESTOSTERONE REPLACEMENT THERAPY

Curated by Dr. Chris Airey, TRT Expert
What is Testosterone Deficiency (TD)?

Low testosterone is a common condition that men can be born with or develop due
to age, stress, disease, physical trauma, an unhealthy lifestyle or
environmental factors.

What are the key symptoms of (TD)?

Men with low testosterone often report low mood, irritability, fatigue, anxiety,
reduced libido or difficulty achieving an erection. Other common symptoms
include brain fog, lack of motivation, low confidence, difficulty losing weight
and difficulty gaining muscle.

How do you test for TD?

Blood testing is the only way to know for sure if you have a testosterone
deficiency. Our Initial Testosterone Blood Test (a simple finger-prick test) can
be taken at home. If the results show that you have low testosterone and you’d
like to start testosterone replacement therapy, UK regulations require you to
take a second, more comprehensive blood test first to ensure that you can safely
start treatment. This one is a venous test which has to be administered by a
nurse or phlebotomist.

How common is TD?

Research has confirmed that testosterone counts in men are significantly lower
than they were just a few decades ago. One in four men over the age of 30 may
have abnormally low testosterone levels according to scientific studies.*

Around the age of 30 testosterone levels naturally begin to decline, but it’s
usually a very gradual process. For most men, testosterone levels drop between
one to two percent each year from the age of 35. Free testosterone levels also
drop considerably as men age, making TD even more common. An increase in
obesity, hormone-disrupting environmental chemicals, and anabolic steroid use is
also making testosterone deficiency in younger men more prevalent than ever.

*The Journal of Clinical Endocrinology & Metabolism

How do TD medications work?

Everyone's medical history is different so our doctor will prescribe a
medication that works specifically for you. Successful hormone therapy involves
getting just the right dose by the right delivery method for your individual
needs. Testosterone replacement therapy involves taking prescribed testosterone
medication in the form of injections, pills, patches, creams, and testosterone
pellets (placed under the skin).

Testosterone injections are the most common form of medication as they are
convenient and most effective for the majority of men.

Is TRT safe and are there any side effects?

Undergoing testosterone replacement therapy is completely safe if you’re treated
by a specialist doctor who regularly monitors your testosterone levels along
with any side effects.

As with all medications, some people may experience side effects - however,
they’re easily controlled and generally avoided with sensible doses and regular
monitoring. Some possible minor side effects include fluid retention, acne, and
increased urination. More severe potential side effects include gynecomastia
(the growth of male breasts), worsening of existing sleep apnea, increased
cholesterol levels, decreased sperm count, infertility, and an increased number
of red blood cells.

Testosterone injections may also increase your risk of certain health problems,
such as heart attack, stroke, blood clots or a worsening of pre-existing
prostate tumours or benign prostatic hyperplasia (enlarged prostate). However,
these side effects can be mostly avoided or controlled through regular
monitoring and other medications.

In order to keep side effects to a minimum you’ll check in to monitor your
testosterone levels and any potential side effects. If you have any concerns or
questions, get in touch with our clinicians - it’s free!


Will I be able to talk to a licensed doctor?

Yes, you willl have a consultation with one of our doctors to discuss your test
results and they can provide a personalised treatment plan tailored to your
needs. Our doctors specialise in TRT for men and are all registered with the
General Medical Council.

Is it legal to purchase testosterone therapy online?

It is legal to purchase TRT online in the UK when buying through a private
clinic such as MANUAL.

Is TRT appropriate for professional athletes?

The World Anti-Doping Agency classifies testosterone as a prohibited substance,
so unfortunately athletes who compete in regulated competitions cannot undergo
Testosterone Replacement Therapy.

How do these blood tests lead to treatment?

Our initial blood test will establish whether you have a testosterone
deficiency. If the first test shows that you have low testosterone you’ll need
to take our second, more comprehensive blood test if you’d like to start TRT -
this is due to UK regulations. If both tests show that you have low T levels,
you’ll discuss suitable treatment options with one of our doctors and during an
in-depth consultation before starting treatment.

How soon will the test arrive?

Our blood test kits usually arrive within three working days. It may take longer
over public holidays.

When will I get my results?

We’ll get in touch to give you your results within two to three business days.
One of our TRT specialists will then walk you through the results, provide
advice, and answer all of your questions.

HAVE A QUESTION?

Whatever it is, get in touch:

0207 427 6085

Mon-Fri 9:00-17:30

help@manual.co

We aim to reply in 24hrs

Email us

We aim to reply in 24hrs

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