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JOURNAL OF REGENERATIVE BIOLOGY AND MEDICINE

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Related Topics

Stem Cell

Rejuvenation

Translational Science

Stem Cell Treatments

Regenerative Medicine

Cell Biology

Stem Cells And Cloning

Regenerative Medicine Of Neural Tissues

Hematopoietic And Cardiovascular Tissues

Progenitor Cells

Artificial Organs

Mesenchymal Stem Cell

Skeletal Muscle Stem Cells

Regulating Mechanisms Of Regeneration

Modes Of Regeneration

Endometrial Stem Cells In Regenerative Medicine

Metamorphosis

Cancer Stem Cells

Covid-19

Coronavirus

Covid-19 (Coronavirus Disease 2019)

Journal of Regenerative Biology and Medicine (ISSN: 2582-385X | ICV 2021 - 100)
is a peer-reviewed scholarly journal and aims to publish the most complete and
reliable source of information on the discoveries and current developments in
the mode of original articles, review articles, case reports, short
communications, etc. in all areas of stem cells and regenerative medicine and
making them available online freely without any restrictions or any other
subscriptions to researchers worldwide. 


Journal of Regenerative Biology and Medicine focuses on the topics include
regenerative medicine therapies, stem cell applications, tissue engineering,
gene and cell therapies, translational medicine, and tissue regeneration.
Interested authors can submit a manuscript through an e-mail attachment to the
Editorial Office alternatively to regenerativebiol@maplejournal.com or
stemcells@maplesjournals.com

Indexing and Archiving: Google Scholar; Crossref; EBSCO; CNKI; Microsoft
Academic; Publons; DRJI; Semantic Scholar; Academic Keys; Scilit; Ulrich's
Periodicals Directory, Dimensions.ai Database and EuroPub database.


Regenerative Biology: In biology, regeneration is the process of renewal,
restoration, and growth that makes genomes, cells, organisms, and ecosystems
resilient to natural fluctuations or events that cause disturbance or damage.
Every species is capable of regeneration, from bacteria to humans. Regeneration
can either be complete where the new tissue is the same as the lost tissue or
incomplete were after the necrotic tissue comes fibrosis. At its most elementary
level, regeneration is mediated by the molecular processes of gene regulation.
Regeneration in biology, however, mainly refers to the morphogenic processes
that characterize the phenotypic plasticity of traits allowing multi-cellular
organisms to repair and maintain the integrity of their physiological and
morphological states. Above the genetic level, regeneration is fundamentally
regulated by asexual cellular processes. Regeneration is different from
reproduction. For example, hydra performs regeneration but reproduce by the
method of budding.


Stem Cells: Stem cells are undifferentiated cells, that can differentiate into
specialized cells and can divide to produce more stem cells. They are found in
multicellular organisms. In mammals, there are two broad types of stem cells:
embryonic stem cells, which are isolated from the inner cell mass of
blastocysts, and adult stem cells, which are found in various tissues. In adult
organisms, stem cells and progenitor cells act as a repair system for the body,
replenishing adult tissues. In a developing embryo, stem cells can differentiate
into all the specialized cells'ectoderm, endoderm, and mesoderm - but also
maintain the normal turnover of regenerative organs, such as blood, skin, or
intestinal tissues.


Tissue Repair and Regeneration: Tissue repair and regeneration following injury
or disease are often thought to recapitulate embryonic development by using
similar molecular and cellular pathways. In addition, many embryonic tissues,
such as the spinal cord, heart, and limbs, have some regenerative potential and
may utilize mechanisms that can be exogenously activated in adult tissues. For
example, BMP signaling regulates nervous system development, and SMAD
reactivation plays a critical role in adult nerve regeneration and repair in
animal models of spinal cord injury. While similar molecular pathways are
utilized during embryogenesis and adult tissue regeneration, recent reports
suggest the mechanisms by which these developmental programs are reactivated and
maintained may vary in adult tissues. Adult fish and amphibians have a
remarkable capacity for tissue regeneration, while mammals have a limited
regenerative capacity.


Rejuvenation: Rejuvenation is a medical discipline focused on the practical
reversal of the aging process. Rejuvenation is distinct from life extension.
Life extension strategies often study the causes of aging and try to oppose
those causes in order to slow aging. Rejuvenation is the reversal of aging and
thus requires a different strategy, namely repair of the damage that is
associated with aging or replacement of damaged tissue with new tissue.
Rejuvenation can be a means of life extension, but most life extension
strategies do not involve rejuvenation.


Tissue Engineering: Tissue engineering is emerging as a significant potential
alternative or complementary solution, whereby tissue and organ failure is
addressed by implanting natural, synthetic, or semisynthetic tissue and organ
mimics that are fully functional from the start, or that grow into the required
functionality. Initial efforts have focused on skin equivalents for treating
burns, but an increasing number of tissue types are now being engineered, as
well as biomaterials and scaffolds used as delivery systems. A variety of
approaches are used to coax differentiated or undifferentiated cells, such as
stem cells, into the desired cell type. Notable results include
tissue-engineered bone, blood vessels, liver, muscle, and even nerve conduits.
As a result of the medical and market potential, there is significant academic
and corporate interest in this technology.


Cell and Organ Regeneration: Some parts of our bodies can repair themselves
quite well after injury, but others don't repair at all. We certainly can't
regrow a whole leg or arm, but some animals Can regrow - or regenerate - whole
body parts. Regeneration means the regrowth of a damaged or missing organ part
from the remaining tissue. As adults, humans can regenerate some organs, such as
the liver. If part of the liver is lost by disease or injury, the liver grows
back to its original size, though not its original shape. And our skin is
constantly being renewed and repaired. Unfortunately, many other human tissues
don't regenerate, and a goal in regenerative medicine is to find ways to
kick-start tissue regeneration in the body or to engineer replacement tissues.


Translational Medicine: Translational science is a multidisciplinary form of
science that bridges the recalcitrant gaps that sometimes exist between
fundamental science and applied science, necessitating something in between to
translate knowledge into applications. The term is most often used in the health
sciences and refers to the translation of bench science, conducted only in a
lab, to bedside clinical practice or dissemination to population-based community
interventions. Translational Medicines: Translational medicine, also called
translational medical science, preclinical research, evidence-based research, or
disease-targeted research, the area of research that aims to improve human
health and longevity by determining the relevance to the human disease of novel
discoveries in the biological sciences.


Translational Science: Translational science is a multidisciplinary form of
science that bridges the recalcitrant gaps that sometimes exist between
fundamental science and applied science, necessitating something in between to
translate knowledge into applications. The term is most often used in the health
sciences and refers to the translation of bench science, conducted only in a
lab, to bedside clinical practice or dissemination to population-based community
interventions.


Models of Regeneration: Discovered centuries ago, regeneration is a fascinating
biological phenomenon that continues to intrigue. The study of regeneration
promises to inform how adult tissues heal and rebuild themselves such that this
process may someday be stimulated in a clinical setting. Although mammals are
limited in their ability to regenerate, closely and distantly related species
alike can perform astonishing regenerative feats. Many different animals
representing almost all phyla harness an innate ability to rebuild missing adult
structures lost to injury. However, it is unclear which aspects of regeneration
are conserved and which are unique to a given context. One aspect of
regeneration that appears to be shared is the use of stem/progenitor cells to
replace missing tissues.


Stem Cell Treatments: Regenerative medicine is an emerging branch of medicine
with the goal of restoring organ and/or tissue function for patients with
serious injuries or chronic disease in which the bodies own responses are not
sufficient enough to restore functional tissue. New and current Regenerative
Medicines can use stem cells to create a living and functional tissues to
regenerate and repair tissue and organs in the body that are damaged due to age,
disease, and congenital defects. Stem cells have the power to go to these
damaged areas and regenerate new cells and tissues by performing a repair and a
renewal process, restoring functionality. Regenerative medicine has the
potential to provide a cure for failing or impaired tissues.


Cellular Therapies: Cellular therapy, also called live cell therapy, cellular
suspensions, glandular therapy, fresh cell therapy, sicca cell therapy,
embryonic cell therapy, and organotherapy - refers to various procedures in
which processed tissue from animal embryos, fetuses or organs, is injected or
taken orally. Products are obtained from specific organs or tissues said to
correspond with the unhealthy organs or tissues of the recipient. Proponents
claim that the recipient's body automatically transports the injected cells to
the target organs, where they supposedly strengthen them and regenerate their
structure. The organs and glands used in cell treatment include the brain,
pituitary, thyroid, adrenals, thymus, liver, kidney, pancreas, spleen, heart,
ovary, testis, and parotid. Several different types of cell or cell extract can
be given simultaneously - some practitioners routinely give up to 20 or more at
once.


Gene Therapy: Gene therapy is an experimental technique that uses genes to treat
or prevent disease. In the future, this technique may allow doctors to treat a
disorder by inserting a gene into a patient's cells instead of using drugs or
surgery. Researchers are testing several approaches to gene therapy, including
replacing a mutated gene that causes disease with a healthy copy of the gene;
Inactivating, or "knocking out", a mutated gene that is functioning improperly;
Introducing a new gene into the body to help fight a disease. Although gene
therapy is a promising treatment option for a number of diseases (including
inherited disorders, some types of cancer, and certain viral infections), the
technique remains risky and is still under study to make sure that it will be
safe and effective. Gene therapy is currently only being tested for the
treatment of diseases that have no other cures.


Immunotherapy: Immunotherapy, also called biologic therapy, is a type of cancer
treatment designed to boost the body's natural defense to fight cancer. It uses
materials either made by the body or in a laboratory to improve, target, or
restore immune system function. It is not entirely clear how immunotherapy
treats cancer. However, it may work in the following ways: Stopping or slowing
the growth of cancer cells; Stopping cancer from spreading to other parts of the
body; Helping the immune system work better at destroying cancer cells. There
are several types of immunotherapy, including monoclonal antibodies,
non-specific immunotherapies, and cancer vaccines.


Stem Cell Transplantation: Stem cell transplantation is a procedure that is most
often recommended as a treatment option for people with leukemia, multiple
myeloma, and some types of lymphoma. It may also be used to treat some genetic
diseases that involve the blood. During a stem cell transplant, diseased bone
marrow (the spongy, fatty tissue found inside larger bones) is destroyed with
chemotherapy and/or radiation therapy and then replaced with highly specialized
stem cells that develop into the healthy bone marrow. Although this procedure
used to be referred to as a bone marrow transplant, today it is more commonly
called a stem cell transplant because it is stem cells in the blood that are
typically being transplanted, not the actual bone marrow tissue.


Ethical and Legal Issues: Stem Cell Research offers great promise for
understanding basic mechanisms of human development and differentiation, as well
as the hope for new treatments for diseases such as diabetes, spinal cord
injury, Parkinson's disease, and myocardial infarction. Pluripotent stem cells
perpetuate themselves in culture and can differentiate into all types of
specialized cells. Scientists plan to differentiate pluripotent cells into
specialized cells that could be used for transplantation.


JOURNAL STATUS

Acceptance Rate62 %Submission to final decision30 daysAcceptance to
publication15 daysCite Score7.00


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