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COLORECTAL CANCER: STATISTICS

Approved by the Cancer.Net Editorial Board, 05/2022

ON THIS PAGE: You will find information about the number of people who are
diagnosed with colorectal cancer each year. You will also read general
information on surviving the disease. Remember, survival rates depend on several
factors. Use the menu to see other pages.


Colorectal cancer is the third most common cancer diagnosed in both men and
women each year in the United States, excluding skin cancer.

This year, an estimated 151,030 adults in the United States will be diagnosed
with colorectal cancer. These numbers include 106,180 new cases of colon cancer
(54,040 men and 52,140 women) and 44,850 new cases of rectal cancer (26,650 men
and 18,200 women). Worldwide, colorectal cancer is the third most diagnosed
cancer. An estimated 1,880,725 people were diagnosed with colorectal cancer in
2020. These numbers include 1,148,515 colon cancer cases and 732,210 rectal
cancer cases.

The number of colorectal cancer cases in the United States has been decreasing
since the mid-1980s. From 2014 to 2018, incidence rates dropped by about 2% each
year in adults aged 50 and older. This was due to increased screening. However,
incidence has been rising in younger people since the mid-1990s (see Risk
Factors and Prevention). From 2014 through 2018, incidence rose by 1.5% each
year in adults younger than 50. Colorectal cancer is estimated to be the fourth
most commonly diagnosed cancer in the United States among men and women aged 30
to 39.

It is estimated that 52,580 deaths (28,400 men and 24,180 women) from this
disease will occur in the United States this year. Colorectal cancer is the
second leading cause of cancer death for men and women combined. It is the third
leading cause of cancer death in men and the third leading cause of cancer death
in women. Worldwide, colorectal cancer is the second leading cause of cancer
death. In 2020, an estimated 915,880 people died from colorectal cancer. This
includes 576,858 people with colon cancer and 339,022 people with rectal cancer.

When colorectal cancer is found early, it can often be cured. The death rate
from this type of cancer in 2019 in the United States was 56% less than what it
was in 1970. This is due to improvements in treatment and increased screening,
which finds colorectal changes before they turn cancerous and cancer at earlier
stages. Overall, the death rate decreased around 2% each year from 2015 to 2019.
However, deaths in adults under age 55 rose 1% per year from 2008 to 2017.
Currently, there are over 1.5 million colorectal cancer survivors in the United
States.

The 5-year survival rate tells you what percent of people live at least 5 years
after the cancer is found. Percent means how many out of 100. The 5-year
survival rate for people with colorectal cancer is 65%. However, survival rates
for colorectal cancer can vary based on several factors, particularly the stage.

The 5-year survival rate of people with localized stage colorectal cancer is
91%. About 37% of patients are diagnosed at this early stage. If the cancer has
spread to surrounding tissues or organs and/or the regional lymph nodes, the
5-year survival rate is 72%. About 36% of patients are diagnosed at this
regional stage. If the cancer has spread to distant parts of the body, the
5-year survival rate is 15%. About 22% of patients are diagnosed at this late
stage. However, for patients who have just 1 or a few tumors that have spread
from the colon or rectum to the lung or liver, surgical removal of these tumors
can sometimes eliminate the cancer, which greatly improves the 5-year survival
rate for these patients.

Survival rates are also available for colon cancer and rectal cancer separately.
For colon cancer, the overall 5-year survival rate for people is 64%. If the
cancer is diagnosed at a localized stage, the survival rate is 91%. If the
cancer has spread to surrounding tissues or organs and/or the regional lymph
nodes, the 5-year survival rate is 72%. If colon cancer has spread to distant
parts of the body, the 5-year survival rate is 14%.

For rectal cancer, the overall 5-year survival rate for people is 67%. If the
cancer is diagnosed at a localized stage, the survival rate is 90%. If the
cancer has spread to surrounding tissues or organs and/or the regional lymph
nodes, the 5-year survival rate is 73%. If the cancer has spread to distant
parts of the body, the 5-year survival rate is 17%.

It is important to remember that statistics on the survival rates for people
with colorectal cancer are an estimate. The estimate comes from annual data
based on the number of people with this cancer in the United States. Also,
experts measure the survival statistics every 5 years. This means the estimate
may not reflect the results of advancements in how colorectal cancer is
diagnosed or treated from the last 5 years. Talk with your doctor if you have
any questions about this information. Learn more about understanding statistics.

Statistics adapted from the American Cancer Society's (ACS) publications, Cancer
Facts & Figures 2022 and Cancer Facts & Figures 2020: Special Section – Cancer
in Adolescents and Young Adults; the ACS website; the International Agency for
Research on Cancer website; and the National Cancer Institute’s Surveillance,
Epidemiology, and End Results (SEER) Program. (All sources accessed January
2022.)

The next section in this guide is Medical Illustrations. It offers drawings of
body parts often affected by colorectal cancer. Use the menu to choose a
different section to read in this guide.

‹ Colorectal Cancer - Introduction up Colorectal Cancer - Medical Illustrations
›
f t k e P


TYPES OF CANCER


COLORECTAL CANCER GUIDE

Cancer.Net Guide
Colorectal Cancer

 * Introduction
 * Statistics
 * Medical Illustrations
 * Risk Factors and Prevention
 * Screening
 * Symptoms and Signs
 * Diagnosis
 * Stages
 * Types of Treatment
 * About Clinical Trials
 * Latest Research
 * Coping with Treatment
 * Follow-Up Care
 * Survivorship
 * Questions to Ask the Health Care Team
 * Additional Resources

View All Pages

Other types of cancer Adenoid Cystic Carcinoma Adrenal Gland Tumor Amyloidosis
Anal Cancer Appendix Cancer Astrocytoma - Childhood Ataxia-Telangiectasia
Beckwith-Wiedemann Syndrome Bile Duct Cancer (Cholangiocarcinoma) Birt-Hogg-Dubé
Syndrome Bladder Cancer Bone Cancer (Sarcoma of Bone) Brain Stem Glioma -
Childhood Brain Tumor Breast Cancer Breast Cancer - Inflammatory Breast Cancer -
Metastatic Breast Cancer, Male Carney Complex Central Nervous System Tumors
(Brain and Spinal Cord) - Childhood Cervical Cancer Childhood Cancer Colorectal
Cancer Cowden Syndrome Craniopharyngioma - Childhood Desmoid Tumor Desmoplastic
Infantile Ganglioglioma, Childhood Tumor Ependymoma - Childhood Esophageal
Cancer Ewing Sarcoma - Childhood and Adolescence Eye Melanoma Eyelid Cancer
Familial Adenomatous Polyposis Familial GIST Familial Malignant Melanoma
Familial Pancreatic Cancer Gallbladder Cancer Gastrointestinal Stromal Tumor -
GIST Germ Cell Tumor - Childhood Gestational Trophoblastic Disease Head and Neck
Cancer Hereditary Breast and Ovarian Cancer Hereditary Diffuse Gastric Cancer
Hereditary Leiomyomatosis and Renal Cell Cancer Hereditary Mixed Polyposis
Syndrome Hereditary Pancreatitis Hereditary Papillary Renal Carcinoma
HIV/AIDS-Related Cancer Juvenile Polyposis Syndrome Kidney Cancer Laryngeal and
Hypopharyngeal Cancer Leukemia - Acute Lymphoblastic - ALL - Childhood Leukemia
- Acute Lymphocytic - ALL Leukemia - Acute Myeloid - AML Leukemia - Acute
Myeloid - AML - Childhood Leukemia - B-cell Prolymphocytic Leukemia and Hairy
Cell Leukemia Leukemia - Chronic Lymphocytic - CLL Leukemia - Chronic Myeloid -
CML Leukemia - Chronic T-Cell Lymphocytic Leukemia - Eosinophilic Li-Fraumeni
Syndrome Liver Cancer Lung Cancer - Non-Small Cell Lung Cancer - Small Cell
Lymphoma - Hodgkin Lymphoma - Hodgkin - Childhood Lymphoma - Non-Hodgkin
Lymphoma - Non-Hodgkin - Childhood Lynch Syndrome Mastocytosis Medulloblastoma -
Childhood Melanoma Meningioma Mesothelioma Multiple Endocrine Neoplasia Type 1
Multiple Endocrine Neoplasia Type 2 Multiple Myeloma MUTYH (or MYH)-Associated
Polyposis Myelodysplastic Syndromes - MDS Nasal Cavity and Paranasal Sinus
Cancer Nasopharyngeal Cancer Neuroblastoma - Childhood Neuroendocrine Tumor of
the Gastrointestinal Tract Neuroendocrine Tumor of the Lung Neuroendocrine Tumor
of the Pancreas Neuroendocrine Tumors Neurofibromatosis Type 1 Neurofibromatosis
Type 2 Nevoid Basal Cell Carcinoma Syndrome Oral and Oropharyngeal Cancer
Osteosarcoma - Childhood and Adolescence Ovarian, Fallopian Tube, and Peritoneal
Cancer Pancreatic Cancer Parathyroid Cancer Penile Cancer Peutz-Jeghers Syndrome
Pheochromocytoma and Paraganglioma Pituitary Gland Tumor Pleuropulmonary
Blastoma - Childhood Prostate Cancer Retinoblastoma - Childhood Rhabdomyosarcoma
- Childhood Salivary Gland Cancer Sarcoma - Kaposi Sarcomas, Soft Tissue Skin
Cancer (Non-Melanoma) Small Bowel Cancer Stomach Cancer Testicular Cancer
Thymoma and Thymic Carcinoma Thyroid Cancer Tuberous Sclerosis Complex Unknown
Primary Uterine Cancer Vaginal Cancer Von Hippel-Lindau Syndrome Vulvar Cancer
Waldenstrom Macroglobulinemia (Lymphoplasmacytic Lymphoma) Werner Syndrome Wilms
Tumor - Childhood Xeroderma Pigmentosum

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