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CELLEFILL™

Your small batch, vial filling machine and containment solution


VIAL FILLING MACHINE AND CONTAINMENT SOLUTION TO FAST TRACK YOUR CELL, GENE AND
BIOLOGICAL THERAPIES

Cellefill is a turnkey, small batch, vial filling machine with an integrated
containment solution.

The GMP compliant system has been designed by aseptic fill/finish experts
Flexicon Liquid Filling and containment experts Franz Ziel.

As a fully integrated solution for the biopharmaceutical industry, Cellefill
maximises production capabilities through recipe driven operation and delivers
enhanced levels of process assurance to accelerate your time to market.

Cellefill optimises your batch security with highly accurate peristaltic pump
performance and integrated environmental monitoring.

Our vial filling machines with integrated containment solutions maximise
production of advanced therapy medicinal products (ATMPs) including cell and
gene therapies (CGT), small batch pharmaceuticals and biologics.


FEATURES AND BENEFITS

 * Fast track your CGT and biological therapies and futureproof for GMP
   compliance
 * Maximise production efficiency with recipe driven, remote set-up and no
   format parts for the entire vial range
 * Highly accurate, precision filling from micro volumes to 50ml with better
   than ±1% achievable at most volumes
 * Fully integrated environmental monitoring system in strategically
   risk-assessed locations
 * Reduced risk of batch loss with flexible in-process controls including 100%
   weight check with zero waste start-up
 * Integrated aseptic vial filling machine and containment solution reduces risk
   and cost
 * Expert guidance and support throughout your project 




CELLEFILL CONFIGURATIONS


 1. ORAB
    
    Sterile product protection of sensitive biologics, antibodies, cell protein
    or nucleic acid-based products. Grade B / ISO 7 cleanroom.


 2. IASP
    
    Sterile product protection of sensitive biologics, antibodies, cell protein
    or nucleic acid-based products. Grade C / ISO 8 cleanroom.


 3. IBIO
    
    Hazardous biologics, individualised or live products requiring highest
    levels of cross contamination control or BSL2 containment. Grade C / ISO 8
    cleanroom.

About us




FLEXICON LIQUID FILLING - SCALABLE FILLING SYSTEMS REDUCE VALIDATION COSTS AND
OPTIMISE INVESTMENT AS DEMAND FOR CAPACITY INCREASES.

Flexicon uses highly accurate peristaltic pump technology in its configurable
aseptic fill/finish systems.

Flexicon offers a range of liquid filling and capping systems that grow with
your business. Flexicon’s portfolio ranges from stand-alone units for hand
filling, through semi-automatic systems, to fully automatic filling, stoppering
and capping machines.

Systems are modular and offer options which allow adaption of each stage of the
fill/finish process, including vial infeed, filling and stoppering and capping.



About our partner Franz Ziel




CONTAINMENT SOLUTIONS FOR OPERATOR AND PRODUCT PROTECTION IN ASEPTIC OR TOXIC
PROCESSES.

With four decades of cleanroom experience and expertise, Franz Ziel is a leading
company in this field. Franz Ziel’s core competency is complex aseptic
processing in the pharmaceutical industry.

Franz Ziel provides customised GMP-compliant, turnkey solutions for all aseptic
processing needs. Minimising interface adaptions and ensuring data integrity,
Franz Ziel is also a full provider of system hardware and services.

These complete solutions enable easier planning and commencement of your
production line, while ensuring optimised workflow.


DOCUMENTATION


 1. CELLEFILL BROCHURE (EN)
    
    Brochure
    
    Download PDF - 963.5kb


 2. PERSONALISED MEDICINE INDUSTRY REPORT (EN)
    
    White paper
    
    Download PDF - 505.6kb


 3. CELL AND GENE THERAPIES: ON THE BRINK OF COMMERCIALISATION (EN)
    
    White paper
    
    Download PDF - 715.9kb


WEBINARS


 1. ON THE BRINK OF COMMERCIALISATION
    
    Addressing the challenges of commercialisation for cell and gene
    therapies/ATMPs
    
    News/Insight


FIND OUT MORE ABOUT CELLEFILL

Fast track your cell and gene and biological therapies

Cellefill™ vial filling machine


CONTACT US

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