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FIND SERVICES
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 * HOME
 * NEWS
   * News
   * News Spotlight
   * News on our COVID-19 work
 * BIG DATA/BOINFORMATICS
   * Bioinformatics services
   * Big Data & Bioinformatics team
   * Big Data & Bioinformatics training
   * HPC infrastructure
   * 
   * Software applications
   * Genome Detective Coronavirus Tool
   * Software available in our HPCs
   * Software developed by us
 * GENOMICS
   * Genomics Infrastructure
   * Amplication & Quantification (PCR, qPCR & ddPCR)
   * DNA/RNA extraction (Automated & Manual)
   * High-throughput Sanger Sequencing
   * Next Generation Sequencing (NGS)
   * 
   * Popular Genomics Services
   * SARS-CoV-2 qPCR (Clinical)
   * HIV Drug Resistance Testing (Clinical)
   * 16S (Metagenomics)
   * Cancer assays (Precision Medicine)
   * ddPCR probe design
   * qPCR panels
   * HLA Typing 1 - A, B, C
   * HIV genotyping (Sanger)
   * HIV genotyping/whole genome (Illumina)
   * RNAseq (Transcriptomics)
   * Sanger Sequencing (Amplicons & Microsatellites)
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   * TB whole genome sequencing
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   * 
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 * PUBLICATIONS
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 * DONATE
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NEWS SPOTLIGHT





The Telegraph





COP28





Devex

PREVIOUS NEWS SPOTLIGHT

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KRISP NEWS




Genomics Sequencing Services with no profit motive to advance Africa's
scientific research, biotech, vaccine, therapy and diagnostics



We're committed to providing affordable genomics sequencing in Africa, with no
profit motive. We aim to unleash genomics' potential, support scientific
research, and foster biotech, vaccine, therapy, and diagnostics development in
Africa.






28th International Workshop on Virus Evolution and Molecular Epidemiology
(VEME2024), Brasilia, Brazil

VEME2024 will be organized at FioCruz in Brasilia, Brazil, during August 4 – 9,
2024. The workshop comprises 6 full days of theoretical lectures, practical
sessions and keynote presentations. VEME2024 will accept 150 participants in 4
modules.




EVENT: HPV, HIV, and Cancer: Bridging the Biological Links, 6 March 2024



Seminar presentation by Prof Lenine Liebenberg 6 March 2024, 1-2 pm, University
of Cape Town (UCT), IDM, Wolfson Pavilion Lecture Theatre, Health Sciences,
Anzio Road, Observatory.






Postdoctoral Research Fellowship in Bioinformatics and Software Engineer



We invite applications from ambitious post doctoral scientists, to undertake
research in a Flagship research programme on epidemics in South Africa.
Interested candidates holding a PhD, and with clear evidence of advance computer
programming and internationally competitive research.






Postdoctoral & PhD Research Fellowships in Population Health Innovation



We invite applications from ambitious post doctoral scientists, to undertake
research in a Flagship research programme on epidemics and modeling in South
Africa. Interested candidates with background in quantitative methods, which may
include Biostatistics, Epidemiology, Econometrics, Data Science, Geography, or
Mathematical Modelling






Digital innovation in healthcare under spotlight at inaugural conference hosted
by Stellenbosch University



Data collection, ethics and use of AI (artificial intelligence) in healthcare
are among the key topics leading global experts addressed at the inaugural
Digital Health Africa? (DHA 2024) conference held recently at Stellenbosch
University's (SU's) Biomedical Research Institute (BMRI).






Meet Professor Tulio de Oliveira, forging a genomic surveillance partnership
between the Wellcome Sanger Institute and South Africa



As head of the largest genomics institute in Africa and new deputy director at
the Genomic Surveillance Unit, Wellcome Sanger Institute, Professor Tulio de
Oliveira hopes close collaboration can be 'world changing.'




MORE NEWS

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PUBLICATIONS SPOTLIGHT




Nature




Science




New England Journal of Medicine

PREVIOUS PUBLICATIONS SPOTLIGHT

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KRISP SCIENTIFIC PUBLICATIONS




Save lives in the next pandemic: ensure vaccine equity now.
Carlson C, Becker D, Happi C, O'Donoghue Z, de Oliveira T, Oyola SO, Poisot T,
Seifert S, Phelan A, Nature (2024), 626(8001):952-953. doi:
10.1038/d41586-024-00545-3:.





SARS-CoV-2 infection in immunosuppression evolves sub-lineages which
independently accumulate neutralization escape mutations.
Lustig G, Ganga Y, Rodel HE, Tegally H, Khairallah A, Jackson L, Cele S, Khan K,
Jule Z, Reedoy K, Karim F, Bernstein M, Ndung'u T, Moosa MS, Archary D, de
Oliveira T, Lessells R, Neher RA, Abdool Karim SS, Sigal A, Virus Evolution
(2024), 10(1):vead075. doi: 10.1093/ve/vead075:.





Investing in Africa's scientific future.
de Oliveira T, Baxter C, Science (2024), ;383(6678):eadn4168. doi:
10.1126/science.adn4168:.





Climate Change and Epidemics 2023 Synthesis Report.
de Oliveira T, Baxter C, for the CLIMADE consortium , (2023), CLIMADE,
Stellenbosch, South Africa. pp1-23, doi 10.25413/sun.24599043:.





NEJM Case 40-2023: A 70-Year-Old Woman with Cough and Shortness of Breath.
Gandhi RT, Castle AC, de Oliveira T, Lessells RJ, New England Journal of
Medicine (2023), 389(26):2468-2476. doi: 10.1056/NEJMcpc2300910:.





Evolution and neutralization escape of the SARS-CoV-2 BA.2.86 subvariant.
Khan K, Lustig G, Römer C, Reedoy K, Jule Z, Karim F, Ganga Y, Bernstein M, Baig
Z, Jackson L, Mahlangu B, Mnguni A, Nzimande A, Stock N, Kekana D, Ntozini B,
van Deventer C, Marshall T, Manickchund N, Gosnell BI, Lessells RJ, Karim QA,
Abdool Karim SS, Moosa MS, de Oliveira T, von Gottberg A, Wolter N, Neher RA,
Sigal A., Nature Communications (2023), 14(1):8078. doi:
10.1038/s41467-023-43703-3:.





Rapid dynamic changes of FL.2 variant: A case report of COVID-19 breakthrough
infection..
Choga WT, Kurusa Gasenna GK, San JE, Ookame T, Gobe I, Chand M, Phafane B, Seru
K, Matshosi P, Zuze B, Ndlovu N, Matsuru T, Maruapula D, Bareng OT, Macheke K,
Kuate-Lere L, Tlale L, Lesetedi O, Tau M, Mbulawa MB, Smith-Lawrence P, Matshaba
M, Shapiro R, Makhema J, Martin DP, de Oliveira T, Lessells RJ, Lockman S,
Gaseitsiwe S, Moyo S, Int J Infect Dis. (2023), 138:91-96. doi:
10.1016/j.ijid.2023.11.011:.



MORE PUBLICATIONS

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KRISP VIDEOS


COVID-19 | News sub-variant being monitored closely
By: Tulio De Oliveira and CERI and KRISP teams




 COVID-19 | News sub-variant being monitored closely

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 COVID-19 in SA | SA scientists don't expect high infection or hospitalisation
numbers

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 First case of COVID-19 sub-variant XBB.1.5 confirmed in South Africa: Prof.
Tulio de Oliveira

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MORE VIDEOS

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KRISP BIOINFORMATICS TOOLS





Genome Detective Coronavirus Typing Tool

Genome Detective Coronavirus Typing Tool for rapid identification and
characterization of novel coronavirus genomes





Genome Detective Dengue Virus Typing Tool

This is a beta version of our Dengue Virus Typing tool. For the mean time, this
tool should be used for evaluation only. Please send feedback to Tulio de
Oliveira.





Genome Detective Zika Typing Tool

This is the first version of the Zika typing tool, which uses phylogenetic
analysis to identify the species and genotype of the virus.





Genome Detective Chikungunya Typing Tool

This is the first version of the Chikungunya typing tool, which uses
phylogenetic analysis to identify the species and genotype of the virus.





Genome Detective Yellow Fever Virus Typing Tool

This is the first version of the Yellow Fever typing tool, which uses
phylogenetic analysis to identify the species and genotype of the virus.





Genome Detective

This is the first version of our Arbovirus typing tool for Chikungunya, Dengue,
Yellow Fever and Zika





REGA HIV Subtyping Tool V3 - Belgium Mirror

Phylogenetic tool to identify the HIV-1 subtypes and recombinants. Query
sequences are analysed for recombination using bootscanning methods. The version
3 contains new CRFs (CRF01_AE to CRF47_BF).


MORE TOOLS



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KRISP has been created by the coordinated effort of the University of
KwaZulu-Natal (UKZN), the Technology Innovation Agency (TIA) and the South
African Medical Research Countil (SAMRC).




Location: K-RITH Tower Building
Nelson R Mandela School of Medicine, UKZN
719 Umbilo Road, Durban, South Africa.
Director: Prof. Tulio de Oliveira


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