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FIND SERVICES Toggle navigation * HOME * NEWS * News * News Spotlight * News on our COVID-19 work * BIG DATA/BOINFORMATICS * Bioinformatics services * Big Data & Bioinformatics team * Big Data & Bioinformatics training * HPC infrastructure * * Software applications * Genome Detective Coronavirus Tool * Software available in our HPCs * Software developed by us * GENOMICS * Genomics Infrastructure * Amplication & Quantification (PCR, qPCR & ddPCR) * DNA/RNA extraction (Automated & Manual) * High-throughput Sanger Sequencing * Next Generation Sequencing (NGS) * * Popular Genomics Services * SARS-CoV-2 qPCR (Clinical) * HIV Drug Resistance Testing (Clinical) * 16S (Metagenomics) * Cancer assays (Precision Medicine) * ddPCR probe design * qPCR panels * HLA Typing 1 - A, B, C * HIV genotyping (Sanger) * HIV genotyping/whole genome (Illumina) * RNAseq (Transcriptomics) * Sanger Sequencing (Amplicons & Microsatellites) * Sanger Sequencing Promotion * Targeted Re-Sequencing (Illumina, ONT, S5Ion) * TB whole genome sequencing * Whole Human Exomes (WES) * * Network for Genomic Surveillance & Genomics Africa * Network for Genomic Surveillance in South Africa (NGS-SA) * Genomics Africa * DIPLOMICS (Distributed Platform in Omics) * PUBLICATIONS * Publications * Publications Spotlight * TALKS & TRAINING * Talks * Training & Capacity Buliding * Translational Science Breakfast * TRANSLATIONAL SCIENCE * Business development unit * Scientific sales brochure * Stanford SPARK Global affiliation * * SPARK South Africa & BioDurban * SPARK call for projects * BioDurban - Biotechnology Incubator of Durban * ABOUT US * Contact us * Faculty, Scientists & Students * Grants support unit * News about our work * Wellness program * YouTube videos * * KRISP Faculty is associted with * CAPRISA NRF CoE * DIPLOMICS (Distributed Platform in Omics) * H3Africa Bioinformatics Network (H3AbioNet) * NIH IDeEA Consortium * SA Medical Research Council (SAMRC) * Technology Innovation Agency (TIA) * University of Washington (DGH) * DONATE * Donate via UKZN Foundation -------------------------------------------------------------------------------- NEWS SPOTLIGHT The Telegraph COP28 Devex PREVIOUS NEWS SPOTLIGHT -------------------------------------------------------------------------------- KRISP NEWS Genomics Sequencing Services with no profit motive to advance Africa's scientific research, biotech, vaccine, therapy and diagnostics We're committed to providing affordable genomics sequencing in Africa, with no profit motive. We aim to unleash genomics' potential, support scientific research, and foster biotech, vaccine, therapy, and diagnostics development in Africa. 28th International Workshop on Virus Evolution and Molecular Epidemiology (VEME2024), Brasilia, Brazil VEME2024 will be organized at FioCruz in Brasilia, Brazil, during August 4 9, 2024. The workshop comprises 6 full days of theoretical lectures, practical sessions and keynote presentations. VEME2024 will accept 150 participants in 4 modules. EVENT: HPV, HIV, and Cancer: Bridging the Biological Links, 6 March 2024 Seminar presentation by Prof Lenine Liebenberg 6 March 2024, 1-2 pm, University of Cape Town (UCT), IDM, Wolfson Pavilion Lecture Theatre, Health Sciences, Anzio Road, Observatory. Postdoctoral Research Fellowship in Bioinformatics and Software Engineer We invite applications from ambitious post doctoral scientists, to undertake research in a Flagship research programme on epidemics in South Africa. Interested candidates holding a PhD, and with clear evidence of advance computer programming and internationally competitive research. Postdoctoral & PhD Research Fellowships in Population Health Innovation We invite applications from ambitious post doctoral scientists, to undertake research in a Flagship research programme on epidemics and modeling in South Africa. Interested candidates with background in quantitative methods, which may include Biostatistics, Epidemiology, Econometrics, Data Science, Geography, or Mathematical Modelling Digital innovation in healthcare under spotlight at inaugural conference hosted by Stellenbosch University Data collection, ethics and use of AI (artificial intelligence) in healthcare are among the key topics leading global experts addressed at the inaugural Digital Health Africa? (DHA 2024) conference held recently at Stellenbosch University's (SU's) Biomedical Research Institute (BMRI). Meet Professor Tulio de Oliveira, forging a genomic surveillance partnership between the Wellcome Sanger Institute and South Africa As head of the largest genomics institute in Africa and new deputy director at the Genomic Surveillance Unit, Wellcome Sanger Institute, Professor Tulio de Oliveira hopes close collaboration can be 'world changing.' MORE NEWS -------------------------------------------------------------------------------- PUBLICATIONS SPOTLIGHT Nature Science New England Journal of Medicine PREVIOUS PUBLICATIONS SPOTLIGHT -------------------------------------------------------------------------------- KRISP SCIENTIFIC PUBLICATIONS Save lives in the next pandemic: ensure vaccine equity now. Carlson C, Becker D, Happi C, O'Donoghue Z, de Oliveira T, Oyola SO, Poisot T, Seifert S, Phelan A, Nature (2024), 626(8001):952-953. doi: 10.1038/d41586-024-00545-3:. SARS-CoV-2 infection in immunosuppression evolves sub-lineages which independently accumulate neutralization escape mutations. Lustig G, Ganga Y, Rodel HE, Tegally H, Khairallah A, Jackson L, Cele S, Khan K, Jule Z, Reedoy K, Karim F, Bernstein M, Ndung'u T, Moosa MS, Archary D, de Oliveira T, Lessells R, Neher RA, Abdool Karim SS, Sigal A, Virus Evolution (2024), 10(1):vead075. doi: 10.1093/ve/vead075:. Investing in Africa's scientific future. de Oliveira T, Baxter C, Science (2024), ;383(6678):eadn4168. doi: 10.1126/science.adn4168:. Climate Change and Epidemics 2023 Synthesis Report. de Oliveira T, Baxter C, for the CLIMADE consortium , (2023), CLIMADE, Stellenbosch, South Africa. pp1-23, doi 10.25413/sun.24599043:. NEJM Case 40-2023: A 70-Year-Old Woman with Cough and Shortness of Breath. Gandhi RT, Castle AC, de Oliveira T, Lessells RJ, New England Journal of Medicine (2023), 389(26):2468-2476. doi: 10.1056/NEJMcpc2300910:. Evolution and neutralization escape of the SARS-CoV-2 BA.2.86 subvariant. Khan K, Lustig G, Römer C, Reedoy K, Jule Z, Karim F, Ganga Y, Bernstein M, Baig Z, Jackson L, Mahlangu B, Mnguni A, Nzimande A, Stock N, Kekana D, Ntozini B, van Deventer C, Marshall T, Manickchund N, Gosnell BI, Lessells RJ, Karim QA, Abdool Karim SS, Moosa MS, de Oliveira T, von Gottberg A, Wolter N, Neher RA, Sigal A., Nature Communications (2023), 14(1):8078. doi: 10.1038/s41467-023-43703-3:. Rapid dynamic changes of FL.2 variant: A case report of COVID-19 breakthrough infection.. Choga WT, Kurusa Gasenna GK, San JE, Ookame T, Gobe I, Chand M, Phafane B, Seru K, Matshosi P, Zuze B, Ndlovu N, Matsuru T, Maruapula D, Bareng OT, Macheke K, Kuate-Lere L, Tlale L, Lesetedi O, Tau M, Mbulawa MB, Smith-Lawrence P, Matshaba M, Shapiro R, Makhema J, Martin DP, de Oliveira T, Lessells RJ, Lockman S, Gaseitsiwe S, Moyo S, Int J Infect Dis. (2023), 138:91-96. doi: 10.1016/j.ijid.2023.11.011:. MORE PUBLICATIONS -------------------------------------------------------------------------------- KRISP VIDEOS COVID-19 | News sub-variant being monitored closely By: Tulio De Oliveira and CERI and KRISP teams COVID-19 | News sub-variant being monitored closely -------------------------------------------------------------------------------- COVID-19 in SA | SA scientists don't expect high infection or hospitalisation numbers -------------------------------------------------------------------------------- First case of COVID-19 sub-variant XBB.1.5 confirmed in South Africa: Prof. Tulio de Oliveira -------------------------------------------------------------------------------- MORE VIDEOS -------------------------------------------------------------------------------- KRISP BIOINFORMATICS TOOLS Genome Detective Coronavirus Typing Tool Genome Detective Coronavirus Typing Tool for rapid identification and characterization of novel coronavirus genomes Genome Detective Dengue Virus Typing Tool This is a beta version of our Dengue Virus Typing tool. For the mean time, this tool should be used for evaluation only. Please send feedback to Tulio de Oliveira. Genome Detective Zika Typing Tool This is the first version of the Zika typing tool, which uses phylogenetic analysis to identify the species and genotype of the virus. Genome Detective Chikungunya Typing Tool This is the first version of the Chikungunya typing tool, which uses phylogenetic analysis to identify the species and genotype of the virus. Genome Detective Yellow Fever Virus Typing Tool This is the first version of the Yellow Fever typing tool, which uses phylogenetic analysis to identify the species and genotype of the virus. Genome Detective This is the first version of our Arbovirus typing tool for Chikungunya, Dengue, Yellow Fever and Zika REGA HIV Subtyping Tool V3 - Belgium Mirror Phylogenetic tool to identify the HIV-1 subtypes and recombinants. Query sequences are analysed for recombination using bootscanning methods. The version 3 contains new CRFs (CRF01_AE to CRF47_BF). MORE TOOLS -------------------------------------------------------------------------------- KRISP has been created by the coordinated effort of the University of KwaZulu-Natal (UKZN), the Technology Innovation Agency (TIA) and the South African Medical Research Countil (SAMRC). Location: K-RITH Tower Building Nelson R Mandela School of Medicine, UKZN 719 Umbilo Road, Durban, South Africa. Director: Prof. Tulio de Oliveira * * *