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OPEN SCIENCE DATA REPOSITORY

The NASA Open Science Data Repository (OSDR) enables access to space-related
data from experiments and missions that investigate biological and health
responses of terrestrial life to spaceflight. The goal of OSDR is to enable
multi-modal and multi-hierarchical fundamental space life science data be reused
toward basic science, applied science, and operational outcomes for space
exploration and knowledge discovery. These data include ‘omics, phenotypic,
physiological, behavioral, hardware, environmental telemetry; raw, processed;
tabular, text, code, bioimaging, and video.

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LATEST NEWS




OSDR at ASGSR 2024

Check out the OSDR Team at ASGSR 2024 The Open Science Data Repository team will
be at ASGSR this year,…

Open Science Success Stories with Dr Keith Siew

Open Science Success Stories: Dr Keith Siew Welcome to our “Open Science Success
Stories”. These narratives showcase insights gleaned from…

Meet the Authors – October 2024

“Meet the Authors”: Space Health Factors in Publications Enabled by Open Science
Welcome to “Meet the Authors”, OSDR’s newest series…

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BY THE NUMBERS

NASA Open Science Data Repositories expands scientists’ access to space-related
experiments that explore the biological response of terrestrial biology to
spaceflight environments. Our mission is to maximize the utilization of the
valuable biological research resources and enable new discoveries.


TODAY

509

STUDIES

973

DATASETS


LATEST DATASETS


OSD-702

Effects of 32 Days Aboard the ISS on Quadricep Tendon Nanomechanics (Quadricep
femoris tendon, RR-1 and Atomic Force Microscopy) (ALSDA)




OSD-718

Effects of 32 Days Aboard the ISS on Gastrocnemius Tendon Nanomechanics
(Gastrocnemius tendon, RR-1 and Atomic Force Microscopy) (ALSDA)




OSD-723

Substrate Matters: Ionic Silver Alters Lettuce Growth, Nutrient Uptake, and Root
Microbiome in a Hydroponics System (GENOMICS)




OSD-479

The impact of deep space radiation on cognitive performance: From biological sex
to biomarkers to countermeasures (Elevated Plus Maze, Novel Object Recognition,
Open Field, Radial Arm Water Maze, and Three Chamber Social
Isolation/Interaction) (ALSDA)




OSD-783

Multidirectional effect of low-intensity electrical myostimulation on gene
expression and phenotype in thigh and calf muscles after one week of disuse –
soleus data (TRANSCRIPTOMICS)




PUBLICATION HIGHLIGHT

Aging and putative frailty biomarkers are altered by spaceflight

Human space exploration poses health risks that lead to molecular changes in
astronauts, such as genomic instability, mitochondrial dysfunction, and
increased inflammation, which are similar to aging-related shifts on Earth.
Using murine and astronaut data from NASA’s GeneLab, JAXA, and Inspiration4
missions, researchers assessed biological markers associated with frailty,
aging, and sarcopenia in space, revealing gene expression changes that may
signal a frailty-like condition in astronauts. These findings suggest that
spaceflight-induced changes may mirror those in aging, indicating the potential
value of a frailty index for monitoring astronaut health.

Learn More about Publication Highlight



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DATA VISUALIZATION

GeneLab’s latest software release includes a new visualization portal to
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enhanced portal includes a new search interface, new plots and layout, and
advanced settings to customize the plots.

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RadLab is a portal that aims to provide a single point of access to radiation
telemetry data from multiple databases maintained by multiple space agencies.

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The Environmental Data App (EDA) is a portal where users can visualize and
compare ISS (International Space Station) cabin environmental telemetry data and
radiation data gathered from spaceflight missions.

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TESTIMONIALS

Sally Ha, GL4HS 2019 Cohort

“The GL4HS program gave me the skills and confidence to pursue an undergraduate
degree in bioinformatics, and I hope that it continues to inspire students to
reach for their highest potential!”

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OPEN SCIENCE PROJECTS

Open Science Projects primary goals aim to increase collaborative scientific
data sharing, analysis, and more rapid scientific advancement.





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