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Oct 16, 2022


THE ROLE OF BLOOD PRESSURE MANAGEMENT IN STROKE PREVENTION: CURRENT STATUS AND
FUTURE PROSPECTS

Keisuke Narita, Satoshi Hoshide, Kazuomi Kario

Expert Rev Cardiovasc Ther. 2022 Oct 16 [Epub ahead of print]

INTRODUCTION Stroke is the second-leading cause of death worldwide and the
second-leading cause of disability-adjusted life-years. It is well-known that
hypertension is a significant risk factor for cardiovascular events, including
stroke. AREAS COVERED Recent interventional trials have demonstrated the
superiority of intensive blood pressure (BP) control for prevention of
cardiovascular events compared to standard BP control. Notably, in the Strategy
of Blood Pressure Intervention in Elderly Hypertensive Patients (STEP) trial,
intensive BP control showed superiority in the prevention of stroke events in
elderly hypertensive patients. Novel medications such as angiotensin
receptor-neprilysin inhibitors and sodium glucose cotransporter 2 inhibitors
have the potential to suppress various CVD events including stroke.
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JASON WESTIN, MD, MS, FACP

1.5 CME / MOC / NCPD


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Non-pharmacological antihypertensive therapies such as renal denervation have
demonstrated BP-lowering effects and may be useful for stroke prevention.
Additionally, new methods and systems of BP monitoring including various kinds
of nighttime BP measurement devices, wearable devices, and methods using
information and communication technology can be used to assess the
pathophysiology of BP variability as a risk factor and an event trigger of
stroke incidence. EXPERT OPINION Novel therapies and new technologies for BP
evaluation strongly support the development of individualized anticipatory
medicine, which should be useful for the prevention of stroke.
Source: Expert Review of Cardiovascular Therapy

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