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Potentially Practice-Changing Only
EvidenceUpdated 20 Jun 2023

recent AIDS diagnosis associated with increased risk of suicide, and HIV
transmission through injection drug use associated with increased risk of death
from substance use or by violence or accident in adults with HIV infection in
Europe (AIDS 2023 Jan 1)

View in Overview of HIV Infection

EvidenceUpdated 20 Jun 2023

higher-dose corticosteroids may decrease 28-day mortality and nosocomial
infection compared to lower-dose corticosteroids in adults hospitalized with
severe-to-critical COVID-19 (Ann Am Thorac Soc 2023 Apr)

View in COVID-19 Management

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EvidenceUpdated 19 Jun 2023

modern external ring fixation may have increased loss of reduction/implant
failure but similar risk of amputation, infection, soft tissue problems,
nonunion, or malunion compared to internal fixation in adults ≤ 64 years old
having surgery for severe open diaphyseal or metaphyseal tibial shaft fractures
(J Bone Joint Surg Am 2022 Jun 15)

View in Tibial Shaft Fractures

Guideline SummaryUpdated 16 Jun 2023

American Urological Association/Society for Urologic Oncology (AUA/SUO)
recommendations on management of hormone-sensitive metastatic prostate cancer
(AUA 2023 Apr)

View in Management of Hormone-sensitive Metastatic Prostate Cancer

Drug/Device AlertUpdated 16 Jun 2023

FDA grants marketing authorization of Eroxon topical gel (Futura Medical
Developments Limited) to treat erectile dysfunction in male adults ≥ 22 years
old (FDA Press Release 2023 Jun 13)

View in Erectile Dysfunction

Drug/Device AlertUpdated 16 Jun 2023

sotagliflozin (Inpefa) FDA approved to reduce risk of cardiovascular death,
hospitalization for heart failure, and urgent heart failure visits in adults
with heart failure or type 2 diabetes, chronic kidney disease, and other
cardiovascular risk factors (FDA Label 2023 May)

View in Heart Failure With Reduced Ejection Fraction (HFrEF)

EvidenceUpdated 16 Jun 2023

telemedicine-based disease monitoring may not reduce flares at 6-12 months in
adults with inflammatory bowel disease (Cochrane Database Syst Rev 2023 May 4)

View in Maintenance Therapy for Crohn Disease in Adults

Drug/Device AlertUpdated 16 Jun 2023

ferric carboxymaltose (Injectafer) receives expanded FDA approval for treatment
of iron deficiency to improve exercise capacity in adults with heart failure and
New York Heart Association Class II/III (FDA Label 2023 May)

View in Treatment of Iron Deficiency Anemia in Adults

Drug/Device AlertUpdated 16 Jun 2023

ferric carboxymaltose (Injectafer) receives expanded FDA approval for treatment
of iron deficiency to improve exercise capacity in adults with heart failure and
New York Heart Association Class II/III (FDA Label 2023 May)

View in Heart Failure With Reduced Ejection Fraction (HFrEF)

Drug/Device AlertUpdated 16 Jun 2023

ferric carboxymaltose (Injectafer) receives expanded FDA approval for treatment
of iron deficiency to improve exercise capacity in adults with heart failure and
New York Heart Association Class II/III (FDA Label 2023 May)

View in Anemia of Inflammation

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