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PUSH THE BOUNDS OF SCIENCE MAKE LIFE-CHANGING MEDICINES

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REGENERON NEWS: FEB 3RD

Regeneron Reports Fourth Quarter and Full Year 2022 Financial and Operating
Results

REGENERON NEWS: JAN 31ST

Regeneron Announces Investor Conference Presentations

REGENERON NEWS: JAN 30TH

Dupixent® (dupilumab) Approved by European Commission as the First and Only
Targeted Medicine Indicated for Eosinophilic Esophagitis

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Now approved for
a new indication

Now approved for
a new indication

Explore our Spectacular Science

Our scientists are building the medicines of tomorrow, marrying the best of
biology and technology to revolutionize how we target and treat serious
diseases.

Explore our revolutionary technology


SOLVING THE HUMAN BODY’S MOST COMPLEX MYSTERIES


SCIENTIFIC TRAILBLAZERS

Following the science leads to unexpected breakthroughs and diverse areas of
study.

Therapeutic Research Areas


DEVELOPING NEW MEDICINES FOR SERIOUS DISEASES

A primarily ‘homegrown’ pipeline of potential medicines for dozens of diseases.

Our Clinical Pipeline



35 YEARS OF CHALLENGES AND TRIUMPHS

Our story is unusual, with remarkable consistency of leadership and purpose in
our efforts to accelerate the drug discovery and development process.

More About Us


Explore our clinical trials

The discoveries never stop as we work to help people with serious diseases.
Clinical trials allow us to carefully test and collect data about
investigational products before they can be approved for use. Learn more about
our clinical trials or find a relevant one near you.

Find trials

REGENERON PERSPECTIVES

MORE GENOMICS, LESS FEAR

The genome is the how and why that define us

By: Adolfo Ferrando, MD, PhD Executive Director, Therapeutic Area Genetics,
Oncology, Regeneron Genetics Center

OUR ANNUAL MATERIALS PEOPLE, PERFORMANCE & PURPOSE

In 2021, we remained relentless in our quest to harness the power of science to
improve patient lives.

Review 2021 Highlights

Download Our
Responsibility Report


DOING WELL BY DOING GOOD

Through responsible business practices and with the highest standards of
integrity,
we rise to any challenge with characteristic drive and a focus on scientific
innovation.
Our next generation of responsibility goals span three areas:

Improving lives
Integrity and excellence
Sustainable Communities

MOVING AT PANDEMIC SPEED

We’re applying our novel technologies to respond swiftly to public health
infectious disease outbreaks like Ebola, MERS and COVID-19.

Rapid Response Efforts

HEROES OF TOMORROW

Alumni of Regeneron’s STEM programs and competitions have won National Medals of
Science, Fields Medals and Nobel Prizes. Our goal? Equip the next generation to
keep the accolades, and the groundbreaking science, coming.

Our Stem Programs


JOIN OUR TEAM

Work with the brightest and most passionate minds in science. Apply to jobs and
internships at Regeneron.

Career Opportunities

Sequencing the next million

The Regeneron Genetics Center® is working to solve the body’s most complex
mysteries, because curiosity is in our genes.

Antibody pioneers

Discover the past, present and future of antibody medicine.

Physican-scientists. Founders.

A place where scientists are heroes. Meet our leaders.

Citizens of science

Transparency is a hallmark of scientific progress. See what our colleagues have
published recently.


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At Regeneron, we've been committed to making a difference in patients' lives for
over 30 years.

We've done this by following the science.

One of the things that's made Regeneron really unique is its willingness to
invest in cutting edge technologies.

We're one of the few companies in the world that go all the way from
foundational discovery, to research, from research to development, to
manufacturing and commercialization.

We do that all at our campuses in New York, New Jersey, Ireland, and the UK.

It's really cool because we go from the really big thought, the really big idea,
all the way to seeing the impact on a person.

One of the things that distinguishes Regeneron is that we are a founder-led
organization.

Both Len and George are scientists, and they've really set the tone of focusing
on science from the very beginning.

And it spreads the through the organization in terms of our mission, our vision,
our activities, our behaviors.

We're one of the unique places where we've put such a big emphasis on human
genetics and deep biology.

Our genetics research is focused on looking at differences in our genes and
connecting that to diseases.

We have a capability of combining human gene sequence data with electronic
medical records.

We have a rich genomic database, and we apply that across our organization,
looking for new for new insights and to advance our research programs.

We've invested in a set of core technologies we call the VelociSuite
Technologies.

These include things like VelociGene, VelocImmune, and together this suite of
technologies gives us an engine for drug discovery.

We can use that engine again, and again, and again to produce new drugs.

Our VelociGene technologies give us an unprecedented ability to precisely
manipulate the mouse genome and work very rapidly.

Likewise, the VelocImmune technology gives us an unprecedented speed in
producing new drugs candidates.

So at a high level in drug development, there are really three key questions
that we need to answer.

One is does it work? Is it safe? And the third is can we produce it?

Before we can even start to explore whether it works, part of the role in
pre-clinical development is to establish whether it's safe and also develop a
manufacturing process by which we can produce it.

So, I see ourselves as a link between the discovery world and the manufacturing
facility where they will produce the drugs that we can test in clinical trials
and ultimately also do commercial production.

Once we've completed pre-clinical research to confirm safety, we work internally
with our medical experts to develop our trial designs.

We take those designs and work with healthcare providers across the globe to
help us implement clinical trials.

After decades of research at a lab bench and years of clinical trial work, we
take tremendous pride in being able to determine whether we've made a difference
in patient lives.

After completion of our clinical trials and data analysis, we then take that
data to regulatory authorities across the globe, so that they can give us our
stamp of approval.

With this approval, we work with our manufacturing group to switch into high
gear.

All of our drugs, whether they're for a clinical trial or a commercial market,
are made across our manufacturing footprint, in both Rensselaer, New York and
Raheen, Ireland.

Our quality standard is very simple. We want to make something that at the end
of the day, we would put in ourselves, our children, our siblings, our parents,
our grandparents and we have a just tremendous responsibility to get things that
are safe and efficacious to those people.

The commercial organization at Regeneron is responsible and accountable for the
really important step of making sure that our medicines get to patients who need
them.

We want to lead the industry in competitive commercialization and that activity
is powered by our science.

It's really a dream to work at Regeneron where number one is patients and using
science to help them.

I love the commitment to science.

I love that we have foundationally a deeply ethical company.

At Regeneron, we study genetics.

We build cutting edge technologies.

We develop biologic medicines.

We conduct thorough research.

We follow the science.

We bring innovative medicines to patients.

Because the potential.

To use science.

To improve human health is endless.

And we're driven.

By what we've yet to discover.


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Join us for a series decades in the making.

We explore millions of genetic codes, advance drug discovery through technology,
identify powerful genes and triumph against the most challenging diseases.

Follow Regeneron's quest for Spectacular Science.

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