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Effective URL: https://primeinc.org/virtual/integrating-latest-evidence-into-kras-molecular-testing-nsclc?utm_campaign=12WC212&utm_s...
Submission: On September 15 via api from US — Scanned from DE
Effective URL: https://primeinc.org/virtual/integrating-latest-evidence-into-kras-molecular-testing-nsclc?utm_campaign=12WC212&utm_s...
Submission: On September 15 via api from US — Scanned from DE
Form analysis 6 forms found in the DOM
POST
<form method="POST" action="" id="webinar-multi-reg-form">
<fieldset>
<legend class="sr-only">Registration</legend>
<div class="sr-only">
<input type="checkbox"
value="{"auto_approve":true,"require_phone":false,"live_event":true,"live_event_pc":"12WC212","live_event_parent_pc":"12WC212","live_event_title":"Integrating the Latest Evidence Into KRAS Molecular Testing for NSCLC","live_event_type":"Live Webinar","live_event_date":"Tue, Sep 28","live_event_time":"2:00 PM Eastern"}"
name="register_for[]" id="r-12WC212" checked="">
<label for="r-12WC212"> Integrating the Latest Evidence Into KRAS Molecular Testing for NSCLC <br>Tuesday, Sep 28, 2021 at 2:00 PM Eastern </label>
</div>
<button type="submit" class="btn btn-lg btn-primary center-block"> Sign Up & Register <i class="arrow-icon arrow-icon-right"></i>
</button>
<small class="center-block text-center mt-1">Register for this live event after creating a PRIME account.</small>
<div class="clearfix pt-2"></div>
<h3 class="h6 text-center pb-1">Register for Related Live Webinar</h3>
<ul class="list-unstyled mb-0 linked-reg-form-selections">
<li class="mb-0 pb-0">
<div class="form-group row clearfix mb-0">
<div class="col-md-1 col-xs-2 text-right">
<input type="checkbox"
value="{"auto_approve":true,"require_phone":false,"live_event":true,"live_event_pc":"12WC213","live_event_parent_pc":"12WC213","live_event_title":"Applying Evidence-Based Treatment Strategies in NSCLC with KRAS Mutations","live_event_type":"Live Webinar","live_event_date":"Tue, Nov 30","live_event_time":"2:00 PM Eastern"}"
name="register_for[]" id="r-12WC213" checked="">
</div>
<div class="col-md-11 col-xs-10 text-sm" style="padding-left: 5px">
<label for="r-12WC213">
<b>
<a href="https://primeinc.org/12WC213">
Applying Evidence-Based Treatment Strategies in NSCLC with KRAS Mutations
</a>
</b>
<br>Tuesday, Nov 30, 2021 at 2:00 PM Eastern </label>
</div>
</div>
</li>
</ul>
</fieldset>
</form>POST //primeinc.org/virtual/integrating-latest-evidence-into-kras-molecular-testing-nsclc?utm_campaign=12WC212&utm_source=prime&utm_medium=email&hr=prime&action=reg&mh=37ccc20e0fad989cc76db6266827c4b2
<form id="surveyform1890" data-surveytype="pre" data-surveyid="1890" data-complete="handlePreSurveyComplete();" data-programcode="12212" class="surveyform" autocomplete="off" method="post"
action="//primeinc.org/virtual/integrating-latest-evidence-into-kras-molecular-testing-nsclc?utm_campaign=12WC212&utm_source=prime&utm_medium=email&hr=prime&action=reg&mh=37ccc20e0fad989cc76db6266827c4b2">
<div class="surveyprogbar">
<div id="surveyprogress1890" class="surveyprogress zero" style="width:0%">0%</div>
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<div>
<div id="questionblock1890_13675" class="questionblock " data-section="" data-sectiontitle="" style="display: block;">
<input type="hidden" class="skipme" name="skipme[13675]" value="0">
<div class="question ">
<p>Approximately how many patients with advanced/metastatic non-small cell lung cancer (NSCLC) do you treat each month?</p>
</div>
<div class="answerarea">
<fieldset>
<legend class="sr-only" style="visibility: hidden;">Approximately how many patients with advanced/metastatic non-small cell lung cancer (NSCLC) do you treat each month?</legend>
<div>
<label for="1890_ans67939" class="single free-response">
<span class="answer" data-id="67939">
<p>Number of patients</p>
</span>: </label><input id="1890_ans67939" class="form-control free " name="answer[13675][free-response][67939]" type="text">
</div>
</fieldset>
</div><!-- .answer-area -->
</div>
<div id="questionblock1890_13676" class="questionblock " data-section="" data-sectiontitle="" style="display: block;">
<input type="hidden" class="skipme" name="skipme[13676]" value="0">
<div class="question ">
<p>Please rate your level of confidence in using molecular diagnostics testing to identify patients with NSCLC who carry <em>KRAS</em> mutations.</p>
</div>
<div class="answerarea">
<fieldset>
<legend class="sr-only" style="visibility: hidden;">Please rate your level of confidence in using molecular diagnostics testing to identify patients with NSCLC who carry KRAS mutations.</legend>
<div>
<label for="s1890_ans67940" class="single single-select">
<input id="s1890_ans67940" name="answer[13676][single-select][]" type="radio" value="67940"> <span class="answer" data-id="67940">
<p>Very low</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67941" class="single single-select">
<input id="s1890_ans67941" name="answer[13676][single-select][]" type="radio" value="67941"> <span class="answer" data-id="67941">
<p>Low</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67942" class="single single-select">
<input id="s1890_ans67942" name="answer[13676][single-select][]" type="radio" value="67942"> <span class="answer" data-id="67942">
<p>Moderate</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67943" class="single single-select">
<input id="s1890_ans67943" name="answer[13676][single-select][]" type="radio" value="67943"> <span class="answer" data-id="67943">
<p>High</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67944" class="single single-select">
<input id="s1890_ans67944" name="answer[13676][single-select][]" type="radio" value="67944"> <span class="answer" data-id="67944">
<p>Very high</p>
</span> </label>
</div>
</fieldset>
</div><!-- .answer-area -->
</div>
<div id="questionblock1890_13677" class="questionblock " data-section="" data-sectiontitle="" style="display: block;">
<input type="hidden" class="skipme" name="skipme[13677]" value="0">
<div class="question ">
<p>How often do you and your team implement <em>KRAS</em> testing as a standard aspect of molecular diagnostics testing in your newly diagnosed patients with advanced/metastatic NSCLC?</p>
</div>
<div class="answerarea">
<fieldset>
<legend class="sr-only" style="visibility: hidden;">How often do you and your team implement KRAS testing as a standard aspect of molecular diagnostics testing in your newly diagnosed patients with advanced/metastatic NSCLC?</legend>
<div>
<label for="s1890_ans67945" class="single single-select">
<input id="s1890_ans67945" name="answer[13677][single-select][]" type="radio" value="67945"> <span class="answer" data-id="67945">
<p>Very frequently</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67946" class="single single-select">
<input id="s1890_ans67946" name="answer[13677][single-select][]" type="radio" value="67946"> <span class="answer" data-id="67946">
<p>Frequently</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67947" class="single single-select">
<input id="s1890_ans67947" name="answer[13677][single-select][]" type="radio" value="67947"> <span class="answer" data-id="67947">
<p>Infrequently</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67948" class="single single-select">
<input id="s1890_ans67948" name="answer[13677][single-select][]" type="radio" value="67948"> <span class="answer" data-id="67948">
<p>Very infrequently</p>
</span> </label>
</div>
</fieldset>
</div><!-- .answer-area -->
</div>
<div id="questionblock1890_13678" class="questionblock " data-section="" data-sectiontitle="" style="display: none;">
<input type="hidden" class="skipme" name="skipme[13678]" value="0">
<div class="question ">
<p>If you are not using <em>KRAS</em> testing frequently or very frequently in your patients with newly diagnosed advanced/metastatic NSCLC, what do you perceive as the key barriers? (Select up to 3)</p>
</div>
<div class="answerarea">
<fieldset>
<legend class="sr-only" style="visibility: hidden;">If you are not using KRAS testing frequently or very frequently in your patients with newly diagnosed advanced/metastatic NSCLC, what do you perceive as the key barriers? (Select up to 3)
</legend>
<div>
<label for="s1890_ans67949" class="multi multi-select">
<input id="s1890_ans67949" name="answer[13678][multi-select][]" type="checkbox" value="67949"> <span class="answer" data-id="67949">
<p>Lack of sufficient biopsy tissue/need for re-biopsy</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67950" class="multi multi-select">
<input id="s1890_ans67950" name="answer[13678][multi-select][]" type="checkbox" value="67950"> <span class="answer" data-id="67950">
<p>Challenges around selecting the appropriate test</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67951" class="multi multi-select">
<input id="s1890_ans67951" name="answer[13678][multi-select][]" type="checkbox" value="67951"> <span class="answer" data-id="67951">
<p>Difficulty interpreting testing results</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67952" class="multi multi-select">
<input id="s1890_ans67952" name="answer[13678][multi-select][]" type="checkbox" value="67952"> <span class="answer" data-id="67952">
<p>Uncertain how to act on results if a mutation is found</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67953" class="multi multi-select">
<input id="s1890_ans67953" name="answer[13678][multi-select][]" type="checkbox" value="67953"> <span class="answer" data-id="67953">
<p>Lack of reimbursement</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67954" class="multi multi-select">
<input id="s1890_ans67954" name="answer[13678][multi-select][]" type="checkbox" value="67954"> <span class="answer" data-id="67954">
<p>Lack of time/inadequate staff support</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67955" class="multi multi-select">
<input id="s1890_ans67955" name="answer[13678][multi-select][]" type="checkbox" value="67955"> <span class="answer" data-id="67955">
<p>Uncertain how to incorporate into existing workflows</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67956" class="multi multi-select">
<input id="s1890_ans67956" name="answer[13678][multi-select][]" type="checkbox" value="67956"> <span class="answer" data-id="67956">
<p>Institutional barriers</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67957" class="multi multi-select">
<input id="s1890_ans67957" name="answer[13678][multi-select][]" type="checkbox" value="67957"> <span class="answer" data-id="67957">
<p>Not applicable; we use <em>KRAS</em> testing frequently</p>
</span> </label>
</div>
</fieldset>
</div><!-- .answer-area -->
</div>
<div id="questionblock1890_13679" class="questionblock " data-section="" data-sectiontitle="" style="display: none;">
<input type="hidden" class="skipme" name="skipme[13679]" value="0">
<div class="question ">
<p>Which of the following types of testing is recommended for identifying clinically relevant <em>KRAS</em> mutations in patients with NSCLC?</p>
</div>
<div class="answerarea">
<fieldset>
<legend class="sr-only" style="visibility: hidden;">Which of the following types of testing is recommended for identifying clinically relevant KRAS mutations in patients with NSCLC?</legend>
<div>
<label for="s1890_ans67958" class="single single-select">
<input id="s1890_ans67958" name="answer[13679][single-select][]" type="radio" value="67958"> <span class="answer" data-id="67958">
<p>Broad gene panel next-generation sequencing (NGS)</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67959" class="single single-select">
<input id="s1890_ans67959" name="answer[13679][single-select][]" type="radio" value="67959"> <span class="answer" data-id="67959">
<p>Fluorescence in-situ hybridization (FISH)</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67960" class="single single-select">
<input id="s1890_ans67960" name="answer[13679][single-select][]" type="radio" value="67960"> <span class="answer" data-id="67960">
<p>Immunohistochemistry (IHC)</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67961" class="single single-select">
<input id="s1890_ans67961" name="answer[13679][single-select][]" type="radio" value="67961"> <span class="answer" data-id="67961">
<p>Reverse transcription polymerase chain reaction (RT-PCR)</p>
</span> </label>
</div>
</fieldset>
</div><!-- .answer-area -->
</div>
<div id="questionblock1890_13680" class="questionblock " data-section="" data-sectiontitle="" style="display: none;">
<input type="hidden" class="skipme" name="skipme[13680]" value="0">
<div class="question ">
<p>Approximately what percentage of patients with NSCLC carry <em>KRAS</em> G12C mutations?</p>
</div>
<div class="answerarea">
<fieldset>
<legend class="sr-only" style="visibility: hidden;">Approximately what percentage of patients with NSCLC carry KRAS G12C mutations?</legend>
<div>
<label for="s1890_ans67962" class="single single-select">
<input id="s1890_ans67962" name="answer[13680][single-select][]" type="radio" value="67962"> <span class="answer" data-id="67962">
<p>2%</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67963" class="single single-select">
<input id="s1890_ans67963" name="answer[13680][single-select][]" type="radio" value="67963"> <span class="answer" data-id="67963">
<p>5%</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67964" class="single single-select">
<input id="s1890_ans67964" name="answer[13680][single-select][]" type="radio" value="67964"> <span class="answer" data-id="67964">
<p>8%</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67965" class="single single-select">
<input id="s1890_ans67965" name="answer[13680][single-select][]" type="radio" value="67965"> <span class="answer" data-id="67965">
<p>13%</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67966" class="single single-select">
<input id="s1890_ans67966" name="answer[13680][single-select][]" type="radio" value="67966"> <span class="answer" data-id="67966">
<p>25%</p>
</span> </label>
</div>
</fieldset>
</div><!-- .answer-area -->
</div>
<div id="questionblock1890_13681" class="questionblock " data-section="" data-sectiontitle="" style="display: none;">
<input type="hidden" class="skipme" name="skipme[13681]" value="0">
<div class="question ">
<p>Primary results from the CodeBreaK100 trial of sotorasib in patients with previously treated, advanced, <em>KRAS</em> G12C-mutated NSCLC showed an objective response rate of?</p>
</div>
<div class="answerarea">
<fieldset>
<legend class="sr-only" style="visibility: hidden;">Primary results from the CodeBreaK100 trial of sotorasib in patients with previously treated, advanced, KRAS G12C-mutated NSCLC showed an objective response rate of?</legend>
<div>
<label for="s1890_ans67967" class="single single-select">
<input id="s1890_ans67967" name="answer[13681][single-select][]" type="radio" value="67967"> <span class="answer" data-id="67967">
<p>17.2%</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67968" class="single single-select">
<input id="s1890_ans67968" name="answer[13681][single-select][]" type="radio" value="67968"> <span class="answer" data-id="67968">
<p>21.0%</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67969" class="single single-select">
<input id="s1890_ans67969" name="answer[13681][single-select][]" type="radio" value="67969"> <span class="answer" data-id="67969">
<p>37.1%</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67970" class="single single-select">
<input id="s1890_ans67970" name="answer[13681][single-select][]" type="radio" value="67970"> <span class="answer" data-id="67970">
<p>44.3%</p>
</span> </label>
</div>
</fieldset>
</div><!-- .answer-area -->
</div>
<div id="questionblock1890_13682" class="questionblock " data-section="" data-sectiontitle="" style="display: none;">
<input type="hidden" class="skipme" name="skipme[13682]" value="0">
<div class="question ">
<p>Julia is a 66-year-old former 30 pack-year smoker who initially presented with a cough, abdominal pain, and weight loss. Imaging revealed multiple bilateral lung nodules as well as multiple abdominal masses. Histology indicates
adenocarcinoma. A sample from one of her abdominal masses is sent for broad gene panel NGS-based testing. Results show a <em>KRAS</em> G12C mutation, with no mutations found in <em>EGFR, ALK, ROS1, BRAF, NTRK, MET,</em> or <em>RET</em>.
Which of the following is an NCCN-preferred first-line treatment option for this patient?</p>
</div>
<div class="answerarea">
<fieldset>
<legend class="sr-only" style="visibility: hidden;">Julia is a 66-year-old former 30 pack-year smoker who initially presented with a cough, abdominal pain, and weight loss. Imaging revealed multiple bilateral lung nodules as well as
multiple abdominal masses. Histology indicates adenocarcinoma. A sample from one of her abdominal masses is sent for broad gene panel NGS-based testing. Results show a KRAS G12C mutation, with no mutations found in EGFR, ALK, ROS1, BRAF,
NTRK, MET, or RET. Which of the following is an NCCN-preferred first-line treatment option for this patient?</legend>
<div>
<label for="s1890_ans67971" class="single single-select">
<input id="s1890_ans67971" name="answer[13682][single-select][]" type="radio" value="67971"> <span class="answer" data-id="67971">
<p>Adagrasib</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67972" class="single single-select">
<input id="s1890_ans67972" name="answer[13682][single-select][]" type="radio" value="67972"> <span class="answer" data-id="67972">
<p>Sotorasib</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67973" class="single single-select">
<input id="s1890_ans67973" name="answer[13682][single-select][]" type="radio" value="67973"> <span class="answer" data-id="67973">
<p>Pembrolizumab/carboplatin/pemetrexed</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67974" class="single single-select">
<input id="s1890_ans67974" name="answer[13682][single-select][]" type="radio" value="67974"> <span class="answer" data-id="67974">
<p>Pembrolizumab monotherapy</p>
</span> </label>
</div>
<div>
<label for="s1890_ans67975" class="single single-select">
<input id="s1890_ans67975" name="answer[13682][single-select][]" type="radio" value="67975"> <span class="answer" data-id="67975">
<p>Carboplatin/pemetrexed</p>
</span> </label>
</div>
</fieldset>
</div><!-- .answer-area -->
</div>
</div>
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INTEGRATING THE LATEST EVIDENCE INTO KRAS MOLECULAR TESTING FOR NSCLC
LIVE WEBINAR SNAPSHOT
Activity Type:
Live Webinar
Duration:
30 minutes
Total Price:
Free
Broadcast Date:
* Tuesday, Sep 28, 2021 at 2:00 PM Eastern (11:00 AM Pacific)
Continuing Education Credits:
* 0.5 CME/CE for Physicians (ACCME)
* 0.5 CME/CE for Physician Assistants (AAPA)
* 0.5 CH/CE for Nurse Practitioners (AANP)
* 0.5 CPE for Pharmacists (ACPE + NABP)
* 0.5 CNE for Nurses (ANCC)
Registration
Integrating the Latest Evidence Into KRAS Molecular Testing for NSCLC
Tuesday, Sep 28, 2021 at 2:00 PM Eastern
Sign Up & Register Register for this live event after creating a PRIME account.
REGISTER FOR RELATED LIVE WEBINAR
* Applying Evidence-Based Treatment Strategies in NSCLC with KRAS Mutations
Tuesday, Nov 30, 2021 at 2:00 PM Eastern
FACULTY
GILBERTO DE LIMA LOPES, JR, MD, MBA, FAMS
Course Director and Speaker
Professor of Clinical Medicine
Medical Director, International Programs
Associate Director, Global Oncology
Interim Chief, Division of Medical Oncology
University of Miami Sylvester Comprehensive Cancer Center
Miami, FL
SOO-RYUM YANG, MD
Speaker
Assistant Attending Pathologist
Memorial Sloan Kettering Cancer Center
New York, NY
MARK A RUBIN, MD
Planner
Medical Director
Humana
Fort Lauderdale, FL
RYAN M BURKE, PHARMD
Planner
Director, Professional Affairs
Pharmacy Technician Certification Board
Washington, DC
JUDITH R SANDS, RN, MSL, BSN, CCM, CPHQ, CPHRM, ARM
Peer Reviewer
Clinical Consultant
Raleigh, NC
AGENDA
I. Practice Insights: Lessons From a New Survey in NSCLC
II. Implications of KRAS Mutations for Patient Prognosis and NSCLC Treatment
Planning
III. Expert Strategies to Overcome Challenges in NSCLC Biomarker Testing
IV. Case Discussion: Who, When, and How to Appropriately Test for KRAS
Mutations
LEARNING OBJECTIVES
* Assess best practices for KRAS biomarker testing in non-small cell lung
cancer (NSCLC)
* Develop evidence-based, biomarker-directed treatment plans for patients with
NSCLC
* Overview
* CE Details & Instructions
* Faculty Disclosures
Intended Audience: physicians, PAs, NPs, pharmacists, nurses specializing in
oncology
The availability of KRAS G12C-targeted agents opens up new opportunities for
biomarker-driven care, affecting about as many non-small cell lung cancer
(NSCLC) patients as those with EGFR-driven tumors. How should molecular
diagnostics be applied to optimal identification of these patients so they can
receive evidence-based care? Get expert advice on who, how, and when to test for
KRAS G12C, including tips for overcoming barriers to appropriate molecular
testing in all patients with NSCLC.
ACCREDITATION INFORMATION
JOINT ACCREDITATION STATEMENT
In support of improving patient care, PRIME® is jointly accredited by the
Accreditation Council for Continuing Medical Education (ACCME), the
Accreditation Council for Pharmacy Education (ACPE), and the American Nurses
Credentialing Center (ANCC) to provide continuing education for the healthcare
team.
INTERPROFESSIONAL TEAMS
This activity was planned by and for the healthcare team, and learners will
receive 0.5 Interprofessional Continuing Education (IPCE) credits for learning
and change.
PHYSICIAN CREDIT DESIGNATION STATEMENT
PRIME® designates this Live activity for a maximum of 0.5 AMA PRA Category 1
Credits™. Physicians should claim only credit commensurate with the extent of
their participation in the activity.
MOC POINTS
Successful completion of this CME activity, which includes participation in the
evaluation component, enables the participant to earn up to 0.5 Medical
Knowledge MOC points in the American Board of Internal Medicine's (ABIM)
Maintenance of Certification (MOC) program. Participants will earn MOC points
equivalent to the amount of CME credits claimed for the activity. It is the CME
activity provider's responsibility to submit participant completion information
to ACCME for the purpose of granting ABIM MOC credit.
PHYSICIAN ASSISTANT ACCREDITATION STATEMENT
PRIME® has been authorized by the American Academy of PAs (AAPA) to award AAPA
Category 1 CME credit for activities planned in accordance with AAPA CME
Criteria. This activity is designated for 0.5 AAPA Category 1 CME credit. PAs
should only claim credit commensurate with the extent of their participation.
NURSE PRACTITIONER ACCREDITATION STATEMENT
PRIME Education is accredited by the American Association of Nurse Practitioners
as an approved provider of nurse practitioner continuing education. Provider
number: 060815. This activity is approved for 0.5 contact hour (which includes
0.5 hour of pharmacology).
PHARMACIST ACCREDITATION STATEMENT
This Application-based activity has been approved for 0.5 contact hour (0.05
CEUs) by PRIME® for pharmacists. The Universal Activity Number for this activity
is JA0007144-0000-21-150-L01-P . Pharmacy CE credits can be submitted to the
NABP upon successful completion of the activity by providing your NABP ID & DOB,
which must be submitted within 60 days of completion. Pharmacists with questions
can contact NABP customer service (help@nabp.pharmacy).
NURSE ACCREDITATION STATEMENT
PRIME® designates this activity for 0.5 contact hour.
OBTAINING CE CREDIT
1. Register using the online form
2. Complete the pre-registration survey
3. Attend the live program in its entirety
4. Complete an online evaluation and post-test
5. Download and/or print a certificate of completion and/or submit CE credits
electronically
Instructions to access CME/CE credit options will be provided at the end of the
program.
METHOD OF PARTICIPATION
This live CME/CE activity requires attendance of the participant during the
entire program and completion of learner assessment tools. The learner will then
receive instructions on how to download and/or print a certificate of completion
and/or submit CE credits electronically.
DEVICE REQUIREMENTS
* Hardware: an Internet-enabled computer, smartphone, tablet, or mobile device
with audio capabilities and Internet connectivity
* Software: the installation of software such as GoToWebinar may be required
The following individuals have identified relevant financial relationships with
commercial interests to disclose:
* Gilberto de Lima Lopes, Jr, MD, MBA, FAMS (Course Director, Speaker)
Consultant – AstraZeneca, Pfizer
Grants / Research Support – AbbVie, Adaptimmune, AstraZeneca, Bavarian
Nordic, Blueprint Medicines, Bristol-Myers Squibb, EMD Serono, ER Squibb Sons
LLC, G1 Therapeutics, GlaxoSmithKline, Janssen, Lilly, Lucence, Merck Sharp &
Dohme, Novartis, Pfizer, Rgenix, Roche, Tesaro, Xilis
Other Financial or Material Support (royalties, patents, etc.) – Boehringer
Ingelheim, Celgene, ER Squibb Sons LLC, Janssen, Pfizer, Seagen (Seattle
Genetics)
* Soo-Ryum Yang, MD (Speaker)
Consultant – Invitae
The following individuals have no relevant financial relationships with
commercial interests to disclose:
* Judith R Sands, RN, MSL, BSN, CCM, CPHQ, CPHRM, ARM (Reviewer)
* Mark A Rubin, MD (Planner)
* Ryan M Burke, PharmD (Planner)
All PRIME staff participating in planning and content development have no
relevant financial relationships with commercial interests to disclose.
FUNDING DISCLOSURE
This activity is provided by PRIME Education. There is no fee to participate.
This activity is supported by educational funding provided by Amgen.
ACCESSIBILITY STATEMENT
At PRIME, we are committed to ensuring that individuals with disabilities can
access all of the content offered by PRIME through our website and other
properties. If you are having trouble accessing primeinc.org, please email
legal@ziffdavis.com for assistance. Please put "ADA Inquiry" in the subject line
of your email.
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BRIDGING THE GAP IN ACCESS TO RHEUMATOLOGY CARE
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0%
Approximately how many patients with advanced/metastatic non-small cell lung
cancer (NSCLC) do you treat each month?
Approximately how many patients with advanced/metastatic non-small cell lung
cancer (NSCLC) do you treat each month?
Number of patients
:
Please rate your level of confidence in using molecular diagnostics testing to
identify patients with NSCLC who carry KRAS mutations.
Please rate your level of confidence in using molecular diagnostics testing to
identify patients with NSCLC who carry KRAS mutations.
Very low
Low
Moderate
High
Very high
How often do you and your team implement KRAS testing as a standard aspect of
molecular diagnostics testing in your newly diagnosed patients with
advanced/metastatic NSCLC?
How often do you and your team implement KRAS testing as a standard aspect of
molecular diagnostics testing in your newly diagnosed patients with
advanced/metastatic NSCLC?
Very frequently
Frequently
Infrequently
Very infrequently
If you are not using KRAS testing frequently or very frequently in your patients
with newly diagnosed advanced/metastatic NSCLC, what do you perceive as the key
barriers? (Select up to 3)
If you are not using KRAS testing frequently or very frequently in your patients
with newly diagnosed advanced/metastatic NSCLC, what do you perceive as the key
barriers? (Select up to 3)
Lack of sufficient biopsy tissue/need for re-biopsy
Challenges around selecting the appropriate test
Difficulty interpreting testing results
Uncertain how to act on results if a mutation is found
Lack of reimbursement
Lack of time/inadequate staff support
Uncertain how to incorporate into existing workflows
Institutional barriers
Not applicable; we use KRAS testing frequently
Which of the following types of testing is recommended for identifying
clinically relevant KRAS mutations in patients with NSCLC?
Which of the following types of testing is recommended for identifying
clinically relevant KRAS mutations in patients with NSCLC?
Broad gene panel next-generation sequencing (NGS)
Fluorescence in-situ hybridization (FISH)
Immunohistochemistry (IHC)
Reverse transcription polymerase chain reaction (RT-PCR)
Approximately what percentage of patients with NSCLC carry KRAS G12C mutations?
Approximately what percentage of patients with NSCLC carry KRAS G12C mutations?
2%
5%
8%
13%
25%
Primary results from the CodeBreaK100 trial of sotorasib in patients with
previously treated, advanced, KRAS G12C-mutated NSCLC showed an objective
response rate of?
Primary results from the CodeBreaK100 trial of sotorasib in patients with
previously treated, advanced, KRAS G12C-mutated NSCLC showed an objective
response rate of?
17.2%
21.0%
37.1%
44.3%
Julia is a 66-year-old former 30 pack-year smoker who initially presented with a
cough, abdominal pain, and weight loss. Imaging revealed multiple bilateral lung
nodules as well as multiple abdominal masses. Histology indicates
adenocarcinoma. A sample from one of her abdominal masses is sent for broad gene
panel NGS-based testing. Results show a KRAS G12C mutation, with no mutations
found in EGFR, ALK, ROS1, BRAF, NTRK, MET, or RET. Which of the following is an
NCCN-preferred first-line treatment option for this patient?
Julia is a 66-year-old former 30 pack-year smoker who initially presented with a
cough, abdominal pain, and weight loss. Imaging revealed multiple bilateral lung
nodules as well as multiple abdominal masses. Histology indicates
adenocarcinoma. A sample from one of her abdominal masses is sent for broad gene
panel NGS-based testing. Results show a KRAS G12C mutation, with no mutations
found in EGFR, ALK, ROS1, BRAF, NTRK, MET, or RET. Which of the following is an
NCCN-preferred first-line treatment option for this patient?
Adagrasib
Sotorasib
Pembrolizumab/carboplatin/pemetrexed
Pembrolizumab monotherapy
Carboplatin/pemetrexed
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* INTEGRATING THE LATEST EVIDENCE INTO KRAS MOLECULAR TESTING FOR NSCLC
* APPLYING EVIDENCE-BASED TREATMENT STRATEGIES IN NSCLC WITH KRAS MUTATIONS
2 Live Webinars on Tue, Sep 28 (2:00 PM Eastern) and Tue, Nov 30 (2:00 PM
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Profession
Profession…Physician Nurse Pharmacist Nurse Practitioner Case Manager Physician
Assistant Resident Medical Assistant Dentist Pharm Tech Health Education
Specialist Respiratory Therapist Physical Therapist Psychologist Dietician
Dietetic Technician HR Specialist Medical Director Fellow Social Worker Genetic
Counselor Other HCP Patient/Caregiver
Practice setting
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Home Health Care Hospital Integrated (ACO, PCMH, etc.) Long Term Care Medical
Practice None / Other Research / Academia Specialty Pharmacy / PBM State /
Federal Government
Specialty
Specialty…Family Medicine Neurology Internal Medicine Hematology / Oncology
Psychiatry Pediatrics Surgery Geriatric Medicine Infectious Disease Cardiology
Gastroenterology Emergency Medicine Critical Care Dermatology Anesthesiology
Pain Management Med / Surg Allergy / Immunology Pulmonology Rheumatology
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