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VISIT ALLELICA AT THE AACR MEETING 2022 | BOOTH #3614
APRIL 8 - 13, 2022

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 * cardioriskSCORE
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   The Science PRS
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 * Allelica Blog
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EMPOWERING THE NEXT GENERATION OF CLINICAL GENOMICS


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ALLELICA HAS CREATED A SECURE AND TRUSTED PLATFORM FOR POLYGENIC RISK SCORE
ANALYSIS AND REPORTING. WE EQUIP HEALTH SYSTEMS AND CLINICAL LABORATORIES WITH
CUTTING-EDGE TOOLS TO REDUCE THE IMPACT OF COMMON DISEASE THROUGH GENOMIC
MEDICINE.


ALLELICA HAS CREATED A SECURE AND TRUSTED PLATFORM FOR POLYGENIC RISK SCORE
ANALYSIS AND REPORTING.
WE EQUIP HEALTH SYSTEMS AND CLINICAL LABORATORIES WITH CUTTING-EDGE TOOLS TO
REDUCE THE IMPACT OF COMMON DISEASE THROUGH GENOMIC MEDICINE.


 
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For Health Systems →
 
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Data-driven
disease prevention

Allelica’s software empowers health systems to reduce the burden of chronic
disease through revolutionary preventive healthcare tools powered by the
integration of patient's clinical and genomic data.



Precision genomic
risk prediction

Allelica’s end-to-end Polygenic Risk Score pipeline provides clinical
laboratories with a secure infrastructure for PRS analysis through to clinical
reporting and can determine a patient's absolute risk of common diseases through
a simple file upload of their genotyped data.






Enabling cutting-edge research

Allelica’s PRS modules for new score discovery and validation perform the work
of a team of bioinformaticians, enabling researchers to generate the
best-performing PRS using multiple gold-standard algorithms in parallel and
achieve publication-ready results without months of bioinformatics efforts.






ALLELICA ISO CERTIFICATION




TRUSTED BY





“With this agreement, Merck confirms its strong commitment in advancing Science
and Technology in the therapeutic area of cardiovascular disorders.”

Antonio Messina, Merck General Manager

Read more →

“MGZ MUNICH HAS STOOD FOR COMPREHENSIVE HUMAN GENETIC DIAGNOSTICS FOR OVER 20
YEARS. INTEGRATING THE POLYGENIC RISK SCORE INTO OUR SERVICES ENABLES US TO
PROVIDE PHYSICIANS WITH A MUCH MORE PRECISE UNDERSTANDING OF THEIR PATIENTS’
ABSOLUTE RISK OF COMPLEX DISEASES, SERVING AS A CRITICAL TOOL IN THE DEVELOPMENT
OF EFFECTIVE PRIMARY PREVENTION STRATEGIES.”

Andreas Laner
Head of Genomics Program NGS

“IN OUR MISSION TO KEEP OUR CLIENTS HEALTHY, WE PROVIDE PERSONALIZED PREVENTION
PLANS BASED ON INTEGRATED MEDICAL AND OMICS DATA - ALLELICA'S TECHNOLOGY HELPS
US TO DO THAT THROUGH DATA-DRIVEN RISK PREDICTION.”

Ernő Duda
Chairman of the Board, Medipredict Chairman of the Board,
Medipredict

“WE’RE DELIGHTED TO PARTNER WITH ALLELICA TO TRANSLATE THE LATEST BREAKTHROUGHS
IN GENOMIC RESEARCH INTO REAL ADVANCES IN CLINICAL CARE.”

Mina Hiona
Director,
Center for Preventive Medicine & Longevity Director,
Center for Preventive Medicine & Longevity


LATEST NEWS

GENOMIC MEDICINE VIRTUAL CONFERENCE

The Rady Children's Institute for Genomic Medicine Virtual Conference 2020,
Integrating Genomic Medicine Across Systems, will dive deep into the latest
innovations in genomic medicine. We will show our work alongside leaders in
research and healthcare on how early polygenic risk score testing can reduce the
lifetime risk of coronary artery disease.

ASHG VIRTUAL MEETING

We are proud to have been selected as a “Reviewer's Choice” by the American
Society of Human Genetics, being rated among the top 10% of abstracts. Our work
will be presented at the ASHG Virtual Meeting 2020 where researchers will come
together to present their latest discoveries and explore new tools &
technologies to transform genomic medicine.

16TH WORLD CONGRESS OF PUBLIC HEALTH

We are very excited to announce our participation in the 16th World Congress of
Public Health, a conference which brings together some of the brightest minds
and latest scientific developments from across the globe. Our presentation will
focus on the role of polygenic risk scores in the prevention of common adult
onset conditions.

ALLELICA OBTAINS ISO CERTIFICATION

Allelica continues to set the industry standard of clinical-grade Polygenic Risk
Score analysis with the addition of two key ISO certifications. ISO 13485 and
ISO 9001 certify that Allelica applies medical device quality management
processes every step of the way.

ALLELICA PRS WEBINAR FEATURED SPEAKERS FROM WORLD-WIDE LEADING INSTITUTIONS

Allelica hosted a Genomeweb webinar on the clinical application of Polygenic
Risk Score in risk assessments. Speakers included Dr. Pradeep Natarajan from the
Massachusetts General Hospital, Dr. Noura Abul-Husn from the Icahn School of
Medicine at Mount Sinai and Allelica CSO, Dr. George Busby.

POLYGENIC RISK SCORE WEBINAR CO-HOSTED WITH CONGENICA

Allelica is joining forces with world leaders in genomic medicine at Congenica
to provide an educational webinar focused on Polygenic Risk Score in clinical
application. The speakers will cover the opportunities and challenges to
widespread implementation for PRS in the UK and beyond.

ALLELICA CSO SPEAKS 2021 GENOMIC SUMMIT

Alongside international scientists, Allelica CSO, George Busby, presented on PRS
at the largest genomics conference in Latin America. George discussed how PRS is
applied in non-European populations and how PRS modulates penetrance of single
gene mutations.

RESEARCH ON THE COST-EFFECTIVENESS OF PRS PUBLISHED IN MEDRXIV

Together with researchers at University of Sydney and Illumina, Inc., Allelica
researchers and health economist, Deo Mujwara, completed a study on the
cost-saving power of PRS for health systems. The study focuses on application of
PRS in heart disease risk assessments, specifically looking at the advantages of
using PRS as a risk enhancing factor in the Pooled Cohort Equation.

PRESS CONFERENCE WITH TOP CARDIOVASCULAR GROUPS AND MERCK

Alongside the three leading cardiovascular scientific societies in Italy,
Allelica hosted a press conference focused on the commercialization of
CardioriskSCORE, the CAD PRS developed by Allelica and published in Circulation.
Participants discussed the impact this has on heart attack risk and its
implications for more effective primary prevention strategies. The conference
was attended by top cardiologists and pharmaceutical companies in Europe.

PHARMAFILE FEATURES INTERVIEW WITH ALLELICA CEO

In the Spring 2021 edition, Pharmafile magazine interviewed Allelica CEO,
Giordano Bottà, on the critical role Polygenic Risk Score plays in assessing
patients’ risk of heart disease. The interview covers the process of PRS
integration in existing cardiovascular disease risk assessment, and discusses
how Allelica is helping to power rapid adoption of PRS for complex disease in
the clinic.

ALLELICA CSO SPEAKS AT OXFORD PERSONALISED MEDICINE WEBINAR

Allelica CSO, George Busby, presented on the increasingly important role of
polygenic risk scores in precision medicine in the UK and beyond, highlighting
the challenges and opportunities for PRS implementation at scale. The webinar
was hosted by the Oxford Personalised Medicine Society, part of the Wellcome
Trust Centre for Human Genetics & University of Oxford.

ALLELICA CEO FEATURED IN CLINICAL OMICS MAGAZINE

Allelica CEO and co-founder, Giordano Bottà, was interviewed as part of an
editorial piece, Polygenic Risk Scores: Taking Hold in the Clinic, in the most
recent version of Clinical Omics. He discusses the growing importance of PRS in
healthcare and the opportunities it presents for chronic disease prevention.

ALLELICA CAD PRS RESEARCH IN CIRCULATION

Allelica researchers identified a critical interaction between PRS for coronary
artery disease (CAD) and LDL cholesterol level.
Their discovery has major implications for clinical decision-making in primary
prevention strategies. The research is now available in the American Heart
Association Journal, Circulation.

GENOMICS VIRTUAL SUMMIT 2020

This event will showcase emerging and innovative applications advancing consumer
& healthcare genomics to accelerate the adoption of precision medicine in
healthcare systems. We will be discussing the life-saving potential of PRS for
heart disease and its power to advance personalized lipid management.

THE COVID-19 HOST GENETICS INITIATIVE

Formed earlier this year, the COVID-19 Host Genetics Initiative is an open
collaboration between scientists around the globe. It is focused on identifying
genetic determinants of disease susceptibility and severity in order to
understand why symptoms manifest in such drastically different ways. As
participants in the initiative, we are developing scores to predict disease
severity. We also built web and mobile digital tools to collect data from
hospitalized patients.

CORONARY ARTERY DISEASE RISK CALCULATOR

Our newest product for healthcare providers calculates patients’ lifetime risk
of developing coronary artery disease based on the integration of genetic and
traditional risk factors using state of the art polygenic risk score. The
interactive tool shows patients how manageable lifestyle changes and therapeutic
interventions can actively lower lifetime risk of heart disease.

GENOMIC MEDICINE VIRTUAL CONFERENCE

The Rady Children's Institute for Genomic Medicine Virtual Conference 2020,
Integrating Genomic Medicine Across Systems, will dive deep into the latest
innovations in genomic medicine. We will show our work alongside leaders in
research and healthcare on how early polygenic risk score testing can reduce the
lifetime risk of coronary artery disease.

ASHG VIRTUAL MEETING

We are proud to have been selected as a “Reviewer's Choice” by the American
Society of Human Genetics, being rated among the top 10% of abstracts. Our work
will be presented at the ASHG Virtual Meeting 2020 where researchers will come
together to present their latest discoveries and explore new tools &
technologies to transform genomic medicine.

16TH WORLD CONGRESS OF PUBLIC HEALTH

We are very excited to announce our participation in the 16th World Congress of
Public Health, a conference which brings together some of the brightest minds
and latest scientific developments from across the globe. Our presentation will
focus on the role of polygenic risk scores in the prevention of common adult
onset conditions.

ALLELICA OBTAINS ISO CERTIFICATION

Allelica continues to set the industry standard of clinical-grade Polygenic Risk
Score analysis with the addition of two key ISO certifications. ISO 13485 and
ISO 9001 certify that Allelica applies medical device quality management
processes every step of the way.

ALLELICA PRS WEBINAR FEATURED SPEAKERS FROM WORLD-WIDE LEADING INSTITUTIONS

Allelica hosted a Genomeweb webinar on the clinical application of Polygenic
Risk Score in risk assessments. Speakers included Dr. Pradeep Natarajan from the
Massachusetts General Hospital, Dr. Noura Abul-Husn from the Icahn School of
Medicine at Mount Sinai and Allelica CSO, Dr. George Busby.

POLYGENIC RISK SCORE WEBINAR CO-HOSTED WITH CONGENICA

Allelica is joining forces with world leaders in genomic medicine at Congenica
to provide an educational webinar focused on Polygenic Risk Score in clinical
application. The speakers will cover the opportunities and challenges to
widespread implementation for PRS in the UK and beyond.
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OUR PRINCIPLES

DATA DRIVEN

Our products are developed and validated using world class datasets and
state-of-the-art technology to ensure the highest level of quality.

SCIENTIFIC RIGOR

We are a group of international scientists and researchers committed to
maintaining standards of academic excellence every step of the way.

HUMAN-CENTRICITY

Everything we do works towards our common goal of providing tangible improvement
in preventive healthcare to help humans live a longer, healthier life.


WHAT WE DO

PERFORM GENETIC RISK ANALYSIS

Allelica's Polygenic Risk Scores for common diseases have the highest predictive
power on the market, allowing physicians to more effectively help patients lower
their risk of life-threatening diseases.

POWER RESEARCH COMMUNITIES

Our secure digital platform enables researchers to construct and validate new
Polygenic Risk Scores on multiple populations using the top algorithms in
parallel to reveal the best Polygenic Risk Scores.




FUNDED BY:





CONTACT US

info@allelica.com+1 2029492834

ALLELICA

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