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> "I have three kids and a husband who is also a busy surgeon, but we make it
> work and I have no regrets about choosing a career in surgery."

Dr. Catherine Dang
Surgical Oncologist, Breast Cancer Program
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WORLD-CLASS SPECIALTY CARE AT YOUR FINGERTIPS


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PEDIATRICS AT GUERIN CHILDREN’S

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YOU CAN TRUST YOU’LL RECEIVE ONLY THE BEST CARE FROM THE WORLD-LEADING SMIDT
HEART INSTITUTE.

Our cardiologists, cardiac surgeons and specialized caregivers are on the
forefront of discovery and improving patient outcomes.

Top specialties:
Heart transplantLung transplantAortic diseaseInterventional cardiologyAdvanced
heart diseaseAdult congenital diseaseElectrophysiology
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> “I woke up from my procedure and took in the deepest breath I’d ever taken,
> and exhaled so long it went for miles.”

Jane – congenital heart patient
Read Jane’s Story



FIND A CLINICAL TRIAL

Cedars-Sinai has a history of pioneering leading-edge research in cardiology and
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disease.

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WE’RE HERE FOR YOU AT EVERY STEP OF YOUR CARE JOURNEY WITH EXPERTS IN 60+ TYPES
OF CANCER.

Our team of leading oncologists aspires to transform cancer medicine for our
patient community and beyond.

Top specialties:
Breast cancerProstate cancerLung cancerLymphoma Colon cancerPancreatic cancer
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> “I was never a person that gave up just because it got tough. I'm living
> today. I'm grateful every single day I open my eyes."

Lois – colon cancer survivor
Read Lois’ Story



FIND A CLINICAL TRIAL

Through the power of clinical trials, the researchers at Cedars-Sinai discover
new opportunities for advancement in cancer research. We want to find better
ways to treat people with cancer.

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GET THE BEST CARE FROM EXPERTS IN OVER 20 PEDIATRIC SPECIALTIES.

At Guerin Children's, our team provides compassionate care for kids of all ages
in our new state-of-the-art facility.

Top specialties:
Pediatric & congenital heartPediatric orthopaedicsPediatric spinePediatric
neurosurgeryPediatric nephrologyPediatric ENTPediatric urologyPediatric
gastroenterology
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> "I want other kids to know it will be OK and that you can still be your own
> person even though you had cancer."

Aiden – pediatric cancer patient
Read Aiden’s Story



FIND A CLINICAL TRIAL

Through the power of clinical trials, the researchers at Cedars-Sinai discover
new opportunities for advancement in pediatric care.

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OUR EXPERT TEAM TREATS 150+ NEUROLOGICAL CONDITIONS. YOU CAN BE ASSURED YOU'VE
COME TO THE RIGHT PLACE.

Our neurologists and neurosurgeons are leaders in the treatment of complex
neurological disorders, and conduct research that brings new hope for patients
and caregivers.

Top specialties:
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> "I couldn't stand. I couldn't sit. And my brain was being totally compromised.
> You saved my life. I am so grateful."

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Cedars-Sinai runs multiple clinical trials in neurology and neurosurgery. These
trials help you access leading therapies and treatments unavailable elsewhere.

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the orthopaedic care that professional athletes choose.

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> took things under my own control."

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you access leading therapies and treatments unavailable elsewhere.

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Whether you need a checkup or you're having a baby, our dedicated care team is
here to support your journey.

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> "It's listening to him laugh and seeing his smile. It just warms my heart up.
> I love his warmth and happiness, and just everything."

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BREAKTHROUGHS AND BREAKING NEWS


HUNTINGTON HEALTH AFFILIATION MARKS TWO YEARS OF PROGRESS

Huntington Health recently marked the two-year anniversary of its affiliation
with Cedars-Sinai Health System. In this brief time, the relationship has
brought important benefits to both organizations, their staffs and the patients
they serve. Huntington Health has added numerous highly respected and deeply
rooted local physicians through the affiliation, enhancing and expanding local
access to expert care and services in Pasadena and the San Gabriel Valley. Among
these: cancer; cardiac, vascular and thoracic surgery; obstetrical and
gynecological care; pediatric subspecialty services; and otolaryngology (ear,
nose and throat). “We chose to affiliate with Cedars-Sinai for many reasons,
including their commitment to grow care at a local level to build healthy,
strong communities,” said Lori J. Morgan, MD, MBA, president and CEO of
Huntington Health. “Under this guiding principle, we’ve come a long way in two
short years.” Thomas M. Priselac, president and CEO of Cedars-Sinai Health
System, credits the commitment of teams at both organizations for the
affiliation’s early achievements. “When we welcomed Huntington Health into the
Cedars-Sinai family in August 2021, we were excited about the many opportunities
to collaborate, as well as the opportunity to share resources and expertise,”
Priselac said. “It is very gratifying that we already have up-and-running
collaborations and new information-technology platforms in place that are
benefiting patients.” The accomplishments of the affiliation include: Patient
care/patient experience—Huntington Health launched CS-Link, a secure, electronic
medical records system that enables patients to communicate with their doctors,
schedule appointments and access their personal health information. A newly
created software system—designed to enhance and simplify the billing/payment
experience for patients—also has been implemented.   Cancer care—Huntington
Cancer Center, an affiliate of Cedars-Sinai Cancer, has seen tremendous growth
in dedicated personnel and services. Additional physicians have joined
Huntington Health to expand the already expert roster of skilled clinicians who
provide comprehensive cancer care—from diagnosis through surgery and recovery.
There are expanded capabilities for infusion for chemotherapy and direct access
to Cedars-Sinai Cancer clinical trials.   Cardiac, vascular and thoracic
surgery—Expert surgeons have joined the Cardiac, Vascular and Thoracic Surgery
Program at Huntington Health to offer a wide range of lifesaving and
life-enhancing surgeries to local patients. New, innovative treatment options
include robotic valve repair, coronary artery bypass grafting, aortic root and
arch surgery, surgical treatment of arrhythmias and minimally invasive thoracic
surgery, making this a state-of-the-art program in the San Gabriel Valley.
Cedars-Sinai is pleased that cardiac surgeon Robbin Cohen, MD, has joined the
faculty and serves as director of the Cardiac Surgery Program at Huntington
Health and professor of Cardiac Surgery in the Department of Cardiac Surgery at
Cedars-Sinai.   These surgeons enable San Gabriel Valley residents to access the
full spectrum of coordinated care offered by the Smidt Heart Institute at
Cedars-Sinai. Cedars-Sinai is best in California and #2 in the U.S. for
Cardiology, Heart & Vascular Surgery, according to U.S. News & World
Report's "Best Hospitals 2023-24" rankings.   Otolaryngology—Cedars-Sinai’s
nationally recognized Otolaryngology Program is now available to adult and
pediatric patients throughout the San Gabriel Valley who have conditions
affecting the ear, nose and throat.   OB-GYN—Fair Oaks Women’s Health, one of
the most respected and longstanding obstetrical and gynecological practices in
the San Gabriel Valley, joined Cedars-Sinai in May. With six specialists, it
will provide patients access to an even greater network of specialized care.  
Pediatric care—Huntington Health’s Neonatal Intensive Care Unit and pediatric
physicians now have access to Cedars-Sinai pediatric subspecialists via
teleconsultations. The affiliation also enables direct transfers to Cedars-Sinai
Guerin Children’s for the most complicated conditions. Outpatient pediatric care
in endocrinology and cardiology is also now available at Huntington Health. “We
are so pleased with the progress this partnership has made over the past two
years, and I’m confident that these strides point to continued success in the
years ahead,” Priselac said. Read more on the Cedars-Sinai Blog: Heart Disease |
When to Get a Second Opinion



MEDICARE 101 – A SIX STEP GUIDE

Medicare isn’t all about plans and premiums; it’s about securing your health and
well-being as you navigate the exciting chapters of life.



PROMISING NEW OPTIONS FOR TREATING AGGRESSIVE PROSTATE CANCER

Cedars-Sinai Cancer investigators have identified two promising new treatment
options for men with recurrent prostate cancer—both of which helped patients
live longer without their disease progressing than the current standard
treatment. The results of their international Phase III clinical trial were
published today in the New England Journal of Medicine. “If these treatments are
approved by the Food and Drug Administration, our results will be practice
changing,” said Stephen Freedland, MD, associate director for Training and
Education and the Warschaw, Robertson, Law Families Chair in Prostate Cancer at
Cedars-Sinai, and lead author of the study. “In the study, both of these new
options improved metastasis-free survival while preserving quality of life.”
Cancer of the prostate, a walnut-sized gland that helps make semen, will be
diagnosed in 288,300 men in the U.S. in 2023, according to American Cancer
Society estimates. For some, treatment may never be needed because they have a
slow-growing form of the disease, but those with more aggressive prostate cancer
are often first treated with surgery or radiation therapy. “Unfortunately, in
about a third of those patients, the cancer recurs within 10 years,” Freedland
said. Patients with aggressive recurrence are treated with androgen deprivation
therapy (ADT), also known as hormone therapy, which reduces the patient’s
production of the male sex hormone testosterone. Testosterone helps prostate
cancer cells grow and spread, and the hormone therapy effectively reduces the
growth-stimulating effects. But Freedland said ADT has two downsides: It doesn’t
completely eliminate testosterone, and it can cause many side effects. “When you
go on ADT, the testosterone level in the blood is reduced, but not completely
eliminated,” Freedland said. “And the concern is that the testosterone that
remains may still be enough to stimulate tumor growth. Also, patients don’t love
the idea of being on hormones.” In this study of 1,068 prostate cancer patients
from 244 sites in 17 countries, Freedland and fellow investigators tested two
experimental interventions—one to address each of these issues. In the
randomized clinical trial, one-third of the patients received ADT plus a
medication called enzalutamide, which blocks the effects of testosterone.
Enzalutamide keeps any testosterone remaining in the blood from stimulating the
growth of cancer cells. Another third of the patients received enzalutamide
alone. This option relied on the medication to block the effects of testosterone
even though testosterone levels in the patients’ blood were not reduced. “We
wanted to see whether enzalutamide on its own was so effective that we didn’t
need the ADT,” Freedland said. The final group of patients received ADT alone,
which is the current standard treatment. Investigators found that the
combination of ADT plus enzalutamide reduced the risk of metastasis or death by
58% over ADT alone. They found that enzalutamide alone reduced the risk of
metastasis or death by 37% over ADT alone. Both treatments maintained quality of
life relative to the ADT alone. “While the combination therapy offers greater
risk reduction, some men might prefer enzalutamide alone. It does a good job of
preventing cancer spread or death, with different side effects that may be more
acceptable for some men,” Freedland said. The next step is for the makers of
enzalutamide to apply for FDA approval, so the experimental therapy can come
into wide use, Freedland said. “Optimizing therapy for patients with aggressive
recurrence after their prostate cancer is initially treated has been an unmet
need,” said Dan Theodorescu, MD, PhD, director of Cedars-Sinai Cancer and the
PHASE ONE Distinguished Chair. “The results of this trial point the way to two
options which the study showed were more effective than current standard of
care, giving these patients and their providers the opportunity to choose a
potentially improved course of therapy that best meets their needs.” Funding:
The study was sponsored by Pfizer and Astellas Pharma, the co-developers of
enzalutamide. Read more on the Cedars-Sinai Blog: Radiation Therapy as Effective
as Surgery for Prostate Cancer



CEDARS-SINAI USES AI TO IDENTIFY PEOPLE WITH ABNORMAL HEART RHYTHMS

Investigators from the Smidt Heart Institute at Cedars-Sinai found that an
artificial intelligence (AI) algorithm can detect an abnormal heart rhythm in
people not yet showing symptoms. The algorithm, which identified hidden signals
in common medical diagnostic testing, may help doctors better prevent strokes
and other cardiovascular complications in people with atrial fibrillation—the
most common type of heart rhythm disorder. Previously developed algorithms have
been primarily used in white populations. This algorithm works in diverse
settings and patient populations, including U.S. veterans and underserved
populations. The findings were published today in the peer-reviewed journal JAMA
Cardiology. “This research allows for better identification of a hidden heart
condition and informs the best way to develop algorithms that are equitable and
generalizable to all patients,” said David Ouyang, MD, a cardiologist in the
Department of Cardiology in the Smidt Heart Institute at Cedars-Sinai, a
researcher in the Division of Artificial Intelligence in Medicine, and senior
author of the study. Experts estimate that about 1 in 3 people with atrial
fibrillation do not know they have the condition. In atrial fibrillation, the
electrical signals in the heart that regulate the pumping of blood from the
upper chambers to the lower chambers are chaotic. This can cause blood in the
upper chambers to pool and form blood clots that can travel to the brain and
trigger an ischemic stroke. To create the algorithm, investigators programmed an
artificial intelligence tool to study patterns found in electrocardiogram
readings. An electrocardiogram is a test that monitors electrical signals from
the heart. People who undergo this test have electrodes placed on their body
that detect the heart’s electrical activity. The program was trained to analyze
electrocardiogram readings taken between Jan. 1, 1987, and Dec. 31, 2022, from
patients seen at two Veterans Affairs health networks. The algorithm was trained
on almost a million electrocardiograms and it accurately predicted patients
would have atrial fibrillation within 31 days. The AI model was also applied to
medical records from patients at Cedars-Sinai and it similarly—and
accurately—predicted cases of atrial fibrillation within 31 days. “This study of
veterans was geographically and ethnically diverse, indicating that the
application of this algorithm could benefit the general population in the U.S.,”
said Sumeet Chugh, MD, director of the Division of Artificial Intelligence in
Medicine in the Department of Medicine and medical director of the Heart Rhythm
Center in the Department of Cardiology. “This research exemplifies one of the
many ways that investigators in the Smidt Heart Institute and the Division of
Artificial Intelligence in Medicine are using AI to address preemptive
management of complex and challenging cardiac conditions.”   The study was a
collaborative effort between physicians and investigators at Cedars-Sinai and
the San Francisco and Palo Alto Veterans Affairs hospitals. First author Neal
Yuan, MD, is an investigator with the Smidt Heart Institute at
Cedars-Sinai. Cedars-Sinai investigators Grant Duffy and John Theurer also
worked on the study. The investigators plan to continue to study the algorithm
as part of prospective clinical trials to learn if it helps identify those at
risk for heart attack and stroke. They also plan to develop more AI algorithms.
Funding: The study was funded by the National Institutes of Health and the U.S.
Department of Veterans Affairs. Read more on the Cedars-Sinai Blog: Treating
Atrial Fibrillation: Risks and Complications



CONFRONTING AGEISM IN HEALTHCARE

Can your age affect how you’re treated at the doctor’s office? Studies say yes,
from preventative care to hospitalizations. A new model aims to confront ageism.




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