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   * Reagent Kit, Advanta™ SARS-CoV-2 Mutation Assay Panel, RUO


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Area of Interest Sample ID and Quality Control Sample ID and Quality Control
with Microfluidics


SAMPLE IDENTIFICATION 

Sample identity and the integrity of genomic data are critical for execution of
superior research. Particularly with complex multiphase studies, aliquots from a
single specimen may be shared among researchers within a laboratory or with
external collaborators and service providers. From high-throughput genomics
centers to biorepositories or centralized cell line banks, ensuring accurate
sample tracking and quality from acquisition through data reporting is a
universally recognized priority.




Overview Workflow Videos and Webinars Customer Stories Resources Publications


CONFIDENTLY TRACK SAMPLES AND ASSESS QUALITY USING AUTOMATED MICROFLUIDICS

Biobanks and genomics centers must overcome several challenges to ensure that
they are providing the highest quality and the correct samples to research
projects.

Sample mix-ups, contamination or handling errors can occur before or after
samples enter the molecular laboratory or storage facility.

Implementing a standard genotyping workflow to confirm the identity and quality
of each sample before analysis represents an ideal solution to maximize the
integrity of study results. 

Processing misidentified, poor-quality or contaminated samples may lead to
incorrect interpretation of results.

The Advanta™ Sample ID Genotyping Panel provides a high-throughput and automated
solution for molecular sample identification, enabling you to simultaneously
perform molecular fingerprinting, quality assessment and integrity confirmation
on every sample. The panel can be used with multiple genomic workflows and is
customizable for any sample type.

 

--------------------------------------------------------------------------------

Sample mix-ups, contamination or handling errors can occur before or after
samples enter the molecular laboratory or storage facility.

--------------------------------------------------------------------------------

Processing misidentified, poor-quality or contaminated samples may lead to
incorrect interpretation of results.


 MOLECULAR SAMPLE IDENTIFICATION


WHAT IS MOLECULAR SAMPLE IDENTIFICATION?

This proactive sample identification system is also known as sample ID or DNA
fingerprinting. Panels of DNA markers are analyzed for each sample, generating a
unique genotype or fingerprint. The genotype obtained is an indelible,
nontransferable identifier for the sample. Carefully selected markers can
provide additional information, such as assessment of sample quality, genetic
gender identity and population prediction.

--------------------------------------------------------------------------------


HOW IS IT USED?

DNA samples can be fingerprinted (identified) prior to distribution.

Sample identity can be confirmed.

 * Compare genetic sex to reported sex.
 * Compare genotypes from distribution sample to accession genotypes.

Low-quality DNA issues can be identified.

 * Low genotype calling rate
 * Sample contamination




BIOMARK™ X IS AWARDED THE OUTSTANDING NEW PRODUCT AWARD AT ISBER 2022.

 

Learn more



ADVANTA SAMPLE ID WORKFLOW

Microfluidics-based fingerprinting provides incredible reproducibility with
automated reaction mix assembly, which enables high-throughput processing up to
9,216 results per run. The nanoliter reaction volume requirements reduce reagent
cost and maximize sample usage.

The workflow allows for maximum targets in individual reactions with no
multiplexing, is directly compatible with common probe-based assays and offers
flexibility with no pre-spotted assays.

 


LEARN FROM THE EXPERT

KELLY NUDELMAN
INDIANA UNIVERSITY SCHOOL OF MEDICINE, INDIANA UNIVERSITY GENETICS BIOBANK


The Indiana University Genetics Biobank (IUGB) at the Indiana University School
of Medicine is a high-throughput biobanking facility that supports numerous
research programs. In this on-demand webinar, Kelly Nudelman describes the IUGB
biobanking pipeline and how they have implemented sample tracking and quality
checks in their workflows.

 

Watch Video

JIANHONG HU, PHD
BAYLOR COLLEGE OF MEDICINE, HUMAN GENOME SEQUENCING CENTER


In this on-demand webinar, Jianhong Hu shares the details of how the Human
Genome Sequencing Center (HGSC) at the Baylor College of Medicine has
implemented SNP Trace™ as part of its NGS workflow. Then, in the same webinar,
learn more about the Advanta Sample ID Genotyping Panel from Luke Stewart,
Senior Field Applications Manager at Standard BioTools.

 

Watch video

LUKE STEWART
SENIOR MANAGER, FIELD APPLICATIONS, STANDARD BIOTOOLS


From high-throughput genomics centers to biorepositories or centralized cell
line banks, ensuring accurate sample tracking and quality from acquisition
through data reporting is a universally recognized priority.

During this webinar, we detail the Advanta Sample ID Genotyping Panel, a 96-SNP
genotyping assay that enables sample identification and quality assessment.
Leveraging microfluidics technology, the Advanta Sample ID workflow offers a
number of benefits including decreased hands-on time and significant cost
savings compared with traditional qPCR methods.

 

Watch video

SYLVIE FORLANI
OPERATIONAL MANAGER, PARIS BRAIN INSTITUTE-ICM BIOBANK


The DNA and cells bank at the Paris Brain Institute-ICM manages more than 50,000
samples and associated data and makes them available to the scientific
community. In this on-demand webinar, Sylvie Forlani, Operational Manager of the
ICM biobank, describes the implementation of the Advanta Sample ID Genotyping
Panel in her facility’s workflow for sample tracking and quality check. She also
introduces a fast, safe and user-friendly analysis pipeline her team developed
to store and analyze each sample.

 

Watch webinar

SARA TOMEI
SIDRA MEDICINE EUROPEAN, MIDDLE EASTERN & AFRICAN SOCIETY FOR BIOPRESERVATION
AND BIOBANKING


Samples used in biomedical research are often collected over years, in some
cases from subjects who have died. Therefore, the value of these samples is
priceless. Sample misidentification and mix-up are unfortunately common problems
in biomedical research and can eventually result in the publication of incorrect
data. In this on-demand webinar, Sara Tomei from Sidra Medicine compares the
Fluidigm SNP Trace and the Agena iPLEX® Sample ID panels for the authentication
of human genomic DNA samples.

Watch webinar


CUSTOMER STORIES

Learn more about how our customers are leveraging Standard BioTools technology

VIEW ALL


KELLY NUDELMAN, PHD


KELLY NUDELMAN AND TAE-HWI SCHWANTES-AN DISCUSS SAMPLE IDENTIFICATION

Learn more

RESOURCES

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Advanta Sample ID Genotyping Panel (101-8045)

Posters

ISBER poster 2019


PUBLICATIONS

Powering over 1,500 scientific publications with our products

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