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(269) 372-3480

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 * Reliable Recombinant Protein Services
   We have more than 15 years of experience producing a wide variety of
   recombinant proteins at the highest quality standards, to keep your program
   moving forward.
   >90% purity, >99% monodispersity
   Diverse protein classes including antibodies, enzymes, hormones
   Optimized expression, purification, & formulation
   Learn More
   
 * Respected Scientists With Diverse Expertise
   Charting your course for drug discovery is challenging, but our
   highly-skilled scientific team can put your journey on the right path from
   square one.
   Proficiency across multiple disciplines
   Veteran management team of industry experts
   Sound approach with proven technologies
   Learn More
   
 * Fit-For-Purpose Products and Customized Workflows
   Understanding the ultimate utility of your reagent from the outset, we work
   alongside you to develop a fit-for-purpose product in order to increase your
   likelihood of a successful discovery program.
   Customized experimental design for your unique needs
   Milestone driven workflows to mitigate risk
   Validated methods for seamless integration of new projects
   Learn More
   
 * Real-Time Communication For Data-Driven Decisions
   Drug discovery can be unpredictable and requires flexibility to overcome
   unforeseen challenges. We continually examine whether projects are running as
   planned and quickly communicate if the unexpected happens.
   Flexible and adaptable experimental designs
   Continual examination of project trajectory
   Real-time analysis and communication
   Learn More
   


RECOMBINANT PROTEIN PRODUCTION SERVICES



Proteos offers a wide range of recombinant protein and antibody expression
platforms, purification methods, analysis tools, and assay services, which
enable us to provide complete production from concept to reagent.  Each service
can be customized to meet your individual project specifications.


ANTIBODY PRODUCTION

Recombinant expression and purification of full-length IgG antibody, F(ab) and
(Fab’)2 antibody fragments, and antibody fusion proteins.  Our antibody
production capabilities include construct design, transient mammalian cell
expression, utilizing in-house or customer provided expression vectors, and
affinity purification. We offer both molecular and enzymatic approaches for
generation of F(ab) and (Fab’)2 antibody fragments.

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PROTEIN EXPRESSION

Mammalian cell, insect cell, and bacterial expression platforms are available
for expression of recombinant proteins.  Complete molecular biology services,
from construct design to endotoxin free plasmid DNA isolation, are also
available.

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PROTEIN PURIFICATION

A comprehensive selection of protein purification and analysis services for
isolation and characterization of recombinant affinity-tagged or native proteins
are available.  In addition, we also offer customizable protein analytics
packages.

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PROTEIN ASSAY SERVICES

The baculovirus titer assay is a plate-based flow cytometry assay, that offers a
quick reproducible method for determining the number of infectious virus
particles/mL.

The thermal shift assay (TSA) is used to measure the thermal denaturation
(melting temperature) of proteins under various conditions.  The assay is useful
for screening pH, ionic strength, ligand binding, and other formulation
additives for their impact on melting temperature. Conditions that increase the
melting temperature are considered stabilizing.

We also offer services for running commercially available kit-based colorimetric
and fluorometric assays.

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LATEST PROTEOS NEWS

Upcoming Events:

Schedule currently pending

Most Recent Announcement:

Expanded Expression Capabilities

Proteos recently upgraded its eukaryotic expression capabilities with the
purchase of 4 high-capacity reach-in incubator/shaker systems built by Eberbach
Corporation, Belleville, Michigan.

Read More


PROTEOS, INC

4717 Campus Drive
Kalamazoo, MI 49008 USA
269.372.3480

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