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Welcome to GOOD LAB Cell Biology of Genome Activation and Membraneless
Organelles, Engineered Living Systems LEARN MORE



NEWS

CRISPR BREAKTHROUGH: NEW TREATMENT FOR GENETIC DISORDERS



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HUMAN TRIALS SUCCESSFUL: BIOENGINEERED ORGANS TRANSPLANTED



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BIOENGINEERING TACKLES PLASTIC POLLUTION HEAD-ON



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ENZYME BREAKTHROUGH: GREEN SOLUTION FOR INDUSTRIAL WASTEWATER



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RECENT PUBLICATIONS

SHARED AND UNIQUE 3D GENOMIC FEATURES OF SUBSTANCE USE DISORDERS ACROSS MULTIPLE
CELL TYPES.

Trang, K. B., Chesi, A., Toikumo, S., Pippin, J. A., Pahl, M. C., O’Brien, J.
M., Amundadottir, L. T., Brown, K. M., Yang, W., Welles, J., Santoleri, D.,
Titchenell, P. M., Seale, P., Zemel, B. S., Wagley, Y., Hankenson, K. D.,
Kaestner, K. H., Anderson, S. A., Kayser, M. S., Wells, A. D., … Grant, S. F. A.
(2024). Shared and unique 3D genomic features of substance use disorders across
multiple cell types. medRxiv : the preprint server for health sciences,
2024.07.18.24310649. https://doi.org/10.1101/2024.07.18.24310649




MYELOID-DERIVED MIR-6236 POTENTIATES ADIPOCYTE INSULIN SIGNALING AND PREVENTS
HYPERGLYCEMIA DURING OBESITY.

Paneru, B. D., Chini, J., McCright, S. J., DeMarco, N., Miller, J., Joannas, L.
D., Henao-Mejia, J., Titchenell, P. M., Merrick, D. M., Lim, H. W., Lazar, M.
A., & Hill, D. A. (2024). Myeloid-derived miR-6236 potentiates adipocyte insulin
signaling and prevents hyperglycemia during obesity. Nature communications,
15(1), 5394. https://doi.org/10.1038/s41467-024-49632-z




3D GENOMIC FEATURES ACROSS >50 DIVERSE CELL TYPES REVEAL INSIGHTS INTO THE
GENOMIC ARCHITECTURE OF CHILDHOOD OBESITY.

Trang, K. B., Pahl, M. C., Pippin, J. A., Su, C., Littleton, S. H., Sharma, P.,
Kulkarni, N. N., Ghanem, L. R., Terry, N. A., O’Brien, J. M., Wagley, Y.,
Hankenson, K. D., Jermusyk, A., Hoskins, J. W., Amundadottir, L. T., Xu, M.,
Brown, K. M., Anderson, S. A., Yang, W., Titchenell, P. M., … Grant, S. F. A.
(2024). 3D genomic features across >50 diverse cell types reveal insights into
the genomic architecture of childhood obesity. medRxiv : the preprint server for
health sciences, 2023.08.30.23294092.
https://doi.org/10.1101/2023.08.30.23294092




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OUR MISSION

We are interested in the unique cell biology of early embryo development.

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