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St. Jude Children's Research Hospital - Homepage
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MEET ELI

At just 6 years old, Eli was diagnosed with bone cancer. His family was referred
to St. Jude for his treatment.

Read This Patient's Story

COVER FOR THE KIDS

Cover for the kids of St. Jude.
Cover for the kids in your community.
Cover for the kids in your life.

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TREATING THE TOUGHEST CASES

Read This Patient's Story

We have some of the world's best survival rates for some of the most aggressive
cancers.

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EXPLORE HOLIDAY GIVING IDEAS

From holiday cards to online store purchases, there are many ways you can give
back to St. Jude kids this holiday season.

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ADVANCING CURES

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What happens when you give the world’s brightest minds the resources to do
something remarkable? Cures.

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EXPLORE ST. JUDE INSPIRE

St. Jude Inspire tells the stories that inspire trust, hope and faith in the
mission that drives us: Finding cures. Saving children.

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ST. JUDE 2022-27 STRATEGIC PLAN

Read our new strategic plan, and learn about our bold vision for the future.

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WATCH OUR PATIENTS AND CELEBRITY FRIENDS

See what celebrities like Jennifer Aniston, Sofía Vergara, Michael Strahan and
Yara Shahidi are saying about their support of St. Jude.

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REACHING THE WORLD

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We share our research with the world, leading a global effort to understand,
treat, and defeat pediatric cancer and other life-threatening diseases.

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SEND A HOLIDAY CARD TO OUR KIDS

Make the holidays even more special for the kids of St. Jude by sending them a
virtual holiday card and message.

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SCIENCE & MEDICINE NEWS

FINDINGS REVEAL NEW MECHANISM OF ACTIVATION FOR ALK

St. Jude Children’s Research Hospital scientists have shed light on the way
ligands bind to and activate ALK, an important target for cancer drug
development.

DISCOVERY OF HOW IMMUNE CELLS SENSE NUTRIENTS OFFERS NEW THERAPEUTIC INSIGHT

St. Jude scientists map nutrient-dependent signaling in T cells, offering
possible new drug targets for treating infectious diseases, cancer and
immune-mediated disorders.

TARGET PREVENTS T-CELL EXHAUSTION, BOOSTS CAR T–CELL RESPONSES

Findings from St. Jude Children’s Research Hospital show how epigenetic
regulation by the enzyme DNMT3A controls T-cell exhaustion providing a target
for improving CAR T–cell immunotherapy.

CHEMOIMMUNOTHERAPY DRAMATICALLY IMPROVED SURVIVAL OF HIGH-RISK NEUROBLASTOMA
PATIENTS

St. Jude phase II clinical trial results suggest monoclonal antibody
hu14.18K322A could help change treatment of children with high-risk
neuroblastoma.

ST. JUDE AT ASH: ANNUAL HEMATOLOGY MEETING HIGHLIGHTS RECENT RESEARCH

Researchers will present their work and share their expertise at ASH2021, the
63rd annual meeting of the American Society of Hematology.

EXHAUSTION AFFECTS CAR T–CELL CLINICAL RESPONSE

Clinical trial data reveals what controls the staying power of T cells,
affecting immunotherapy responses. St. Jude scientists' findings were published
in Cell Reports.