biocytogen.com Open in urlscan Pro
2606:4700:20::ac43:4b75  Public Scan

Submitted URL: http://ec2-100-20-220-134.us-west-2.compute.amazonaws.com/x/d?c=35548632&l=9b6bc8a7-ff25-4f77-9c3c-db0dde8d5d61&r=cb3e69a9-3eb1-466c-9021-c09a34c7285a
Effective URL: https://biocytogen.com/products/other-humanized-model/b-hapoe4-mice/?utm_source=Biocytogen&utm_campaign=b4ee089529-EMAI...
Submission: On October 03 via manual from IN — Scanned from US

Form analysis 7 forms found in the DOM

#

<form role="search" action="#" autocomplete="off" aria-label="Search form">
  <input aria-label="Search input" type="search" class="orig" tabindex="0" name="phrase" placeholder="Search here.." value="" autocomplete="off">
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Name: options

<form name="options" aria-label="Search settings form" autocomplete="off">
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</form>

#

<form role="search" action="#" autocomplete="off" aria-label="Search form">
  <input aria-label="Search input" type="search" class="orig" tabindex="0" name="phrase" placeholder="Search here.." value="" autocomplete="off">
  <input aria-label="Search autocomplete input" type="text" class="autocomplete" tabindex="-1" name="phrase" value="" autocomplete="off" disabled="">
  <input type="submit" value="Start search" style="width:0; height: 0; visibility: hidden;">
</form>

Name: options

<form name="options" aria-label="Search settings form" autocomplete="off">
  <input type="hidden" name="filters_changed" style="display:none;" value="0">
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      <input type="checkbox" value="fx_job_posting" aria-label="Hidden option, ignore please" name="customset[]" checked="checked">
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    <legend>Filter by Categories</legend>
    <div class="categoryfilter asl_sett_scroll">
      <div class="asl_option" tabindex="0">
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        <div class="asl_option_label"> Posts </div>
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POST /products/other-humanized-model/b-hapoe4-mice/#wpcf7-f827-o1

<form action="/products/other-humanized-model/b-hapoe4-mice/#wpcf7-f827-o1" method="post" class="wpcf7-form init" id="request-quote-form-mobile" aria-label="Contact form" novalidate="novalidate" data-status="init">
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            <option value="Anguilla">Anguilla</option>
            <option value="Åland Islands">Åland Islands</option>
            <option value="Albania">Albania</option>
            <option value="Andorra">Andorra</option>
            <option value="United Arab Emirates">United Arab Emirates</option>
            <option value="Argentina">Argentina</option>
            <option value="Armenia">Armenia</option>
            <option value="American Samoa">American Samoa</option>
            <option value="Antarctica">Antarctica</option>
            <option value="French Southern Territories">French Southern Territories</option>
            <option value="Antigua and Barbuda">Antigua and Barbuda</option>
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            <option value="Austria">Austria</option>
            <option value="Azerbaijan">Azerbaijan</option>
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            <option value="Burkina Faso">Burkina Faso</option>
            <option value="Bangladesh">Bangladesh</option>
            <option value="Bulgaria">Bulgaria</option>
            <option value="Bahrain">Bahrain</option>
            <option value="Bahamas">Bahamas</option>
            <option value="Bosnia and Herzegovina">Bosnia and Herzegovina</option>
            <option value="Saint Barthélemy">Saint Barthélemy</option>
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            <option value="Bermuda">Bermuda</option>
            <option value="Bolivia, Plurinational State of">Bolivia, Plurinational State of</option>
            <option value="Brazil">Brazil</option>
            <option value="Barbados">Barbados</option>
            <option value="Brunei Darussalam">Brunei Darussalam</option>
            <option value="Bhutan">Bhutan</option>
            <option value="Bouvet Island">Bouvet Island</option>
            <option value="Botswana">Botswana</option>
            <option value="Central African Republic">Central African Republic</option>
            <option value="Canada">Canada</option>
            <option value="Cocos (Keeling) Islands">Cocos (Keeling) Islands</option>
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            <option value="Comoros">Comoros</option>
            <option value="Cape Verde">Cape Verde</option>
            <option value="Costa Rica">Costa Rica</option>
            <option value="Cuba">Cuba</option>
            <option value="Curaçao">Curaçao</option>
            <option value="Christmas Island">Christmas Island</option>
            <option value="Cayman Islands">Cayman Islands</option>
            <option value="Cyprus">Cyprus</option>
            <option value="Czech Republic">Czech Republic</option>
            <option value="Germany">Germany</option>
            <option value="Djibouti">Djibouti</option>
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            <option value="Dominican Republic">Dominican Republic</option>
            <option value="Algeria">Algeria</option>
            <option value="Ecuador">Ecuador</option>
            <option value="Egypt">Egypt</option>
            <option value="Eritrea">Eritrea</option>
            <option value="Western Sahara">Western Sahara</option>
            <option value="Spain">Spain</option>
            <option value="Estonia">Estonia</option>
            <option value="Ethiopia">Ethiopia</option>
            <option value="Finland">Finland</option>
            <option value="Fiji">Fiji</option>
            <option value="Falkland Islands (Malvinas)">Falkland Islands (Malvinas)</option>
            <option value="France">France</option>
            <option value="Faroe Islands">Faroe Islands</option>
            <option value="Micronesia, Federated States of">Micronesia, Federated States of</option>
            <option value="Gabon">Gabon</option>
            <option value="United Kingdom">United Kingdom</option>
            <option value="Georgia">Georgia</option>
            <option value="Guernsey">Guernsey</option>
            <option value="Ghana">Ghana</option>
            <option value="Gibraltar">Gibraltar</option>
            <option value="Guinea">Guinea</option>
            <option value="Guadeloupe">Guadeloupe</option>
            <option value="Gambia">Gambia</option>
            <option value="Guinea-Bissau">Guinea-Bissau</option>
            <option value="Equatorial Guinea">Equatorial Guinea</option>
            <option value="Greece">Greece</option>
            <option value="Grenada">Grenada</option>
            <option value="Greenland">Greenland</option>
            <option value="Guatemala">Guatemala</option>
            <option value="French Guiana">French Guiana</option>
            <option value="Guam">Guam</option>
            <option value="Guyana">Guyana</option>
            <option value="Hong Kong">Hong Kong</option>
            <option value="Heard Island and McDonald Islands">Heard Island and McDonald Islands</option>
            <option value="Honduras">Honduras</option>
            <option value="Croatia">Croatia</option>
            <option value="Haiti">Haiti</option>
            <option value="Hungary">Hungary</option>
            <option value="Indonesia">Indonesia</option>
            <option value="Isle of Man">Isle of Man</option>
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            <option value="British Indian Ocean Territory">British Indian Ocean Territory</option>
            <option value="Ireland">Ireland</option>
            <option value="Iran, Islamic Republic of">Iran, Islamic Republic of</option>
            <option value="Iraq">Iraq</option>
            <option value="Iceland">Iceland</option>
            <option value="Israel">Israel</option>
            <option value="Italy">Italy</option>
            <option value="Jamaica">Jamaica</option>
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            <option value="Jordan">Jordan</option>
            <option value="Japan">Japan</option>
            <option value="Kazakhstan">Kazakhstan</option>
            <option value="Kenya">Kenya</option>
            <option value="Kyrgyzstan">Kyrgyzstan</option>
            <option value="Cambodia">Cambodia</option>
            <option value="Kiribati">Kiribati</option>
            <option value="Saint Kitts and Nevis">Saint Kitts and Nevis</option>
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            <option value="Lao People's Democratic Republic">Lao People's Democratic Republic</option>
            <option value="Lebanon">Lebanon</option>
            <option value="Liberia">Liberia</option>
            <option value="Libya">Libya</option>
            <option value="Saint Lucia">Saint Lucia</option>
            <option value="Liechtenstein">Liechtenstein</option>
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            <option value="Lesotho">Lesotho</option>
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            <option value="Luxembourg">Luxembourg</option>
            <option value="Latvia">Latvia</option>
            <option value="Macao">Macao</option>
            <option value="Saint Martin (French part)">Saint Martin (French part)</option>
            <option value="Morocco">Morocco</option>
            <option value="Monaco">Monaco</option>
            <option value="Moldova, Republic of">Moldova, Republic of</option>
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            <option value="Marshall Islands">Marshall Islands</option>
            <option value="Macedonia, the former Yugoslav Republic of">Macedonia, the former Yugoslav Republic of</option>
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            <option value="Malta">Malta</option>
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            <option value="Saint Helena, Ascension and Tristan da Cunha">Saint Helena, Ascension and Tristan da Cunha</option>
            <option value="Svalbard and Jan Mayen">Svalbard and Jan Mayen</option>
            <option value="Solomon Islands">Solomon Islands</option>
            <option value="Sierra Leone">Sierra Leone</option>
            <option value="El Salvador">El Salvador</option>
            <option value="San Marino">San Marino</option>
            <option value="Somalia">Somalia</option>
            <option value="Saint Pierre and Miquelon">Saint Pierre and Miquelon</option>
            <option value="Serbia">Serbia</option>
            <option value="South Sudan">South Sudan</option>
            <option value="Sao Tome and Principe">Sao Tome and Principe</option>
            <option value="Suriname">Suriname</option>
            <option value="Slovakia">Slovakia</option>
            <option value="Slovenia">Slovenia</option>
            <option value="Sweden">Sweden</option>
            <option value="Swaziland">Swaziland</option>
            <option value="Sint Maarten (Dutch part)">Sint Maarten (Dutch part)</option>
            <option value="Seychelles">Seychelles</option>
            <option value="Syrian Arab Republic">Syrian Arab Republic</option>
            <option value="Turks and Caicos Islands">Turks and Caicos Islands</option>
            <option value="Chad">Chad</option>
            <option value="Togo">Togo</option>
            <option value="Thailand">Thailand</option>
            <option value="Tajikistan">Tajikistan</option>
            <option value="Tokelau">Tokelau</option>
            <option value="Turkmenistan">Turkmenistan</option>
            <option value="Timor-Leste">Timor-Leste</option>
            <option value="Tonga">Tonga</option>
            <option value="Trinidad and Tobago">Trinidad and Tobago</option>
            <option value="Tunisia">Tunisia</option>
            <option value="Turkey">Turkey</option>
            <option value="Tuvalu">Tuvalu</option>
            <option value="Taiwan, Province of China">Taiwan, Province of China</option>
            <option value="Tanzania, United Republic of">Tanzania, United Republic of</option>
            <option value="Uganda">Uganda</option>
            <option value="Ukraine">Ukraine</option>
            <option value="United States Minor Outlying Islands">United States Minor Outlying Islands</option>
            <option value="Uruguay">Uruguay</option>
            <option value="United States">United States</option>
            <option value="Uzbekistan">Uzbekistan</option>
            <option value="Holy See (Vatican City State)">Holy See (Vatican City State)</option>
            <option value="Saint Vincent and the Grenadines">Saint Vincent and the Grenadines</option>
            <option value="Venezuela, Bolivarian Republic of">Venezuela, Bolivarian Republic of</option>
            <option value="Virgin Islands, British">Virgin Islands, British</option>
            <option value="Virgin Islands, U.S.">Virgin Islands, U.S.</option>
            <option value="Viet Nam">Viet Nam</option>
            <option value="Vanuatu">Vanuatu</option>
            <option value="Wallis and Futuna">Wallis and Futuna</option>
            <option value="Samoa">Samoa</option>
            <option value="Yemen">Yemen</option>
            <option value="South Africa">South Africa</option>
            <option value="Zambia">Zambia</option>
            <option value="Zimbabwe">Zimbabwe</option>
          </select></div>
        <div class="selectric"><span class="label">—Please choose an option—</span><b class="button"></b></div>
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              <li data-index="1" class="">Aruba</li>
              <li data-index="2" class="">Afghanistan</li>
              <li data-index="3" class="">Angola</li>
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              <li data-index="11" class="">American Samoa</li>
              <li data-index="12" class="">Antarctica</li>
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              <li data-index="167" class="">Netherlands</li>
              <li data-index="168" class="">Norway</li>
              <li data-index="169" class="">Nepal</li>
              <li data-index="170" class="">Nauru</li>
              <li data-index="171" class="">New Zealand</li>
              <li data-index="172" class="">Oman</li>
              <li data-index="173" class="">Pakistan</li>
              <li data-index="174" class="">Panama</li>
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              <li data-index="176" class="">Peru</li>
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              <li data-index="183" class="">Portugal</li>
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              <li data-index="205" class="">Serbia</li>
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              <li data-index="229" class="">Taiwan, Province of China</li>
              <li data-index="230" class="">Tanzania, United Republic of</li>
              <li data-index="231" class="">Uganda</li>
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              <li data-index="247" class="">South Africa</li>
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            <option value="Humanized Immune-Checkpoint Mice">Humanized Immune-Checkpoint Mice</option>
            <option value="Immunodeficient Mice">Immunodeficient Mice</option>
            <option value="Humanized Tumor Cell Lines">Humanized Tumor Cell Lines</option>
            <option value="Luciferase Tumor Cell Lines">Luciferase Tumor Cell Lines</option>
            <option value="Cre Mouse/Rat Models">Cre Mouse/Rat Models</option>
            <option value="Humanized Cytokines Mice">Humanized Cytokines Mice</option>
            <option value="Others">Others</option>
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              <li data-index="0" class="selected"></li>
              <li data-index="1" class="">Humanized Immune-Checkpoint Mice</li>
              <li data-index="2" class="">Immunodeficient Mice</li>
              <li data-index="3" class="">Humanized Tumor Cell Lines</li>
              <li data-index="4" class="">Luciferase Tumor Cell Lines</li>
              <li data-index="5" class="">Cre Mouse/Rat Models</li>
              <li data-index="6" class="">Humanized Cytokines Mice</li>
              <li data-index="7" class="last">Others</li>
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                  <li data-index="1" class="">Existing client</li>
                  <li data-index="2" class="">Online Search</li>
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                  <li data-index="4" class="">Promotional Email/Email Marketing</li>
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                  <li data-index="6" class="last">Social Media</li>
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    <input type="hidden" name="_wpcf7_recaptcha_response"
      value="03AFcWeA6BjRL8ACmywNjC0_j46RYmplmcir95wWh5201kJ8oJBNSEgbqpcmCPSLpVyZ8njVImC09m3d_e8QdpyAqlc5Gu5-HIWtjhYpNwSegfzkt8p4DjrPneamCXZmZwyH0j5WvPzqUlh1b2bjfXj3g80mq2hU8TgEHfq1Hqo4PrxwlQn-6enqzFakWXwnvYeFLm9iPrw4ek_vc6xyca8p17SZC4UBn1j7HLHAbA1QiT_S_meZbBW-YTLYGJvmdB0Yrce_Vl1guPru-kOvVBRvZ7Ae0UMF444qJh32SejT6ULXq0QWeZU2Z_GQKTdET9yy5KPQUiMcsUPV1umGAmuB_MEAKH3cGOSUyvQ7rfj7SrAbVhUjuxBU3zu2on4nYt1JPGsYKrFVu-yLBRLgvlYno2jJNhskgjYadEgHMg9h0AIfoeihyZwaexkpM9D_iCT4-R-Bz73Ht9wgAZUND24aN0os-XN0xvco3N6yRkrDZf6eyDVOEyC3dI-LvSHBV8VJcDIwVk_OIUXV80ccMfogJuMIfg1cLAyWkxqdJao-HQo4trlbRIHzHbXU0hThXFwjcZQuCS51L3sMKDelRa5RPid8h2zWZK79gPrCUCOQBbwClzQWoV9KE">
  </div>
  <div class="col-md-12 input-container hard-sides">
    <label>First Name <span class="mailpoet_required">*</span></label>
    <span class="wpcf7-form-control-wrap" data-name="fname"><input size="40" class="wpcf7-form-control wpcf7-text wpcf7-validates-as-required" aria-required="true" aria-invalid="false" value="" type="text" name="fname"></span>
  </div>
  <div class="col-md-12 input-container hard-sides">
    <label>Last Name<span class="mailpoet_required">*</span></label>
    <span class="wpcf7-form-control-wrap" data-name="lname"><input size="40" class="wpcf7-form-control wpcf7-text wpcf7-validates-as-required" aria-required="true" aria-invalid="false" value="" type="text" name="lname"></span>
  </div>
  <div class="col-md-12 input-container hard-sides">
    <label>Company/ Institution<strong>*</strong></label>
    <span class="wpcf7-form-control-wrap" data-name="company"><input size="40" class="wpcf7-form-control wpcf7-text wpcf7-validates-as-required" aria-required="true" aria-invalid="false" value="" type="text" name="company"></span>
  </div>
  <div class="col-md-12 input-container hard-sides">
    <label>Email <span class="mailpoet_required">*</span></label>
    <span class="wpcf7-form-control-wrap" data-name="email"><input size="40" class="wpcf7-form-control wpcf7-email wpcf7-validates-as-required wpcf7-text wpcf7-validates-as-email" aria-required="true" aria-invalid="false" value="" type="email"
        name="email"></span>
  </div>
  <div class="col-md-12 input-container hard-sides">
    <label>Product Name<strong>*</strong></label>
    <span class="wpcf7-form-control-wrap" data-name="product-name"><input size="40" class="wpcf7-form-control wpcf7-text wpcf7-validates-as-required" aria-required="true" aria-invalid="false" value="" type="text" name="product-name"></span>
  </div>
  <div class="col-md-12 input-container hard-sides">
    <label>Country <strong>*</strong></label>
    <span class="wpcf7-form-control-wrap" data-name="country">
      <div class="selectric-wrapper selectric-wpcf7-form-control selectric-wpcf7-select selectric-wpcf7-validates-as-required">
        <div class="selectric-hide-select"><select class="wpcf7-form-control wpcf7-select wpcf7-validates-as-required" aria-required="true" aria-invalid="false" name="country" tabindex="-1">
            <option value="">—Please choose an option—</option>
            <option value="Aruba">Aruba</option>
            <option value="Afghanistan">Afghanistan</option>
            <option value="Angola">Angola</option>
            <option value="Anguilla">Anguilla</option>
            <option value="Åland Islands">Åland Islands</option>
            <option value="Albania">Albania</option>
            <option value="Andorra">Andorra</option>
            <option value="United Arab Emirates">United Arab Emirates</option>
            <option value="Argentina">Argentina</option>
            <option value="Armenia">Armenia</option>
            <option value="American Samoa">American Samoa</option>
            <option value="Antarctica">Antarctica</option>
            <option value="French Southern Territories">French Southern Territories</option>
            <option value="Antigua and Barbuda">Antigua and Barbuda</option>
            <option value="Australia">Australia</option>
            <option value="Austria">Austria</option>
            <option value="Azerbaijan">Azerbaijan</option>
            <option value="Burundi">Burundi</option>
            <option value="Belgium">Belgium</option>
            <option value="Benin">Benin</option>
            <option value="Bonaire, Sint Eustatius and Saba">Bonaire, Sint Eustatius and Saba</option>
            <option value="Burkina Faso">Burkina Faso</option>
            <option value="Bangladesh">Bangladesh</option>
            <option value="Bulgaria">Bulgaria</option>
            <option value="Bahrain">Bahrain</option>
            <option value="Bahamas">Bahamas</option>
            <option value="Bosnia and Herzegovina">Bosnia and Herzegovina</option>
            <option value="Saint Barthélemy">Saint Barthélemy</option>
            <option value="Belarus">Belarus</option>
            <option value="Belize">Belize</option>
            <option value="Bermuda">Bermuda</option>
            <option value="Bolivia, Plurinational State of">Bolivia, Plurinational State of</option>
            <option value="Brazil">Brazil</option>
            <option value="Barbados">Barbados</option>
            <option value="Brunei Darussalam">Brunei Darussalam</option>
            <option value="Bhutan">Bhutan</option>
            <option value="Bouvet Island">Bouvet Island</option>
            <option value="Botswana">Botswana</option>
            <option value="Central African Republic">Central African Republic</option>
            <option value="Canada">Canada</option>
            <option value="Cocos (Keeling) Islands">Cocos (Keeling) Islands</option>
            <option value="Switzerland">Switzerland</option>
            <option value="Chile">Chile</option>
            <option value="China">China</option>
            <option value="Côte d'Ivoire">Côte d'Ivoire</option>
            <option value="Cameroon">Cameroon</option>
            <option value="Congo, the Democratic Republic of the">Congo, the Democratic Republic of the</option>
            <option value="Congo">Congo</option>
            <option value="Cook Islands">Cook Islands</option>
            <option value="Colombia">Colombia</option>
            <option value="Comoros">Comoros</option>
            <option value="Cape Verde">Cape Verde</option>
            <option value="Costa Rica">Costa Rica</option>
            <option value="Cuba">Cuba</option>
            <option value="Curaçao">Curaçao</option>
            <option value="Christmas Island">Christmas Island</option>
            <option value="Cayman Islands">Cayman Islands</option>
            <option value="Cyprus">Cyprus</option>
            <option value="Czech Republic">Czech Republic</option>
            <option value="Germany">Germany</option>
            <option value="Djibouti">Djibouti</option>
            <option value="Dominica">Dominica</option>
            <option value="Denmark">Denmark</option>
            <option value="Dominican Republic">Dominican Republic</option>
            <option value="Algeria">Algeria</option>
            <option value="Ecuador">Ecuador</option>
            <option value="Egypt">Egypt</option>
            <option value="Eritrea">Eritrea</option>
            <option value="Western Sahara">Western Sahara</option>
            <option value="Spain">Spain</option>
            <option value="Estonia">Estonia</option>
            <option value="Ethiopia">Ethiopia</option>
            <option value="Finland">Finland</option>
            <option value="Fiji">Fiji</option>
            <option value="Falkland Islands (Malvinas)">Falkland Islands (Malvinas)</option>
            <option value="France">France</option>
            <option value="Faroe Islands">Faroe Islands</option>
            <option value="Micronesia, Federated States of">Micronesia, Federated States of</option>
            <option value="Gabon">Gabon</option>
            <option value="United Kingdom">United Kingdom</option>
            <option value="Georgia">Georgia</option>
            <option value="Guernsey">Guernsey</option>
            <option value="Ghana">Ghana</option>
            <option value="Gibraltar">Gibraltar</option>
            <option value="Guinea">Guinea</option>
            <option value="Guadeloupe">Guadeloupe</option>
            <option value="Gambia">Gambia</option>
            <option value="Guinea-Bissau">Guinea-Bissau</option>
            <option value="Equatorial Guinea">Equatorial Guinea</option>
            <option value="Greece">Greece</option>
            <option value="Grenada">Grenada</option>
            <option value="Greenland">Greenland</option>
            <option value="Guatemala">Guatemala</option>
            <option value="French Guiana">French Guiana</option>
            <option value="Guam">Guam</option>
            <option value="Guyana">Guyana</option>
            <option value="Hong Kong">Hong Kong</option>
            <option value="Heard Island and McDonald Islands">Heard Island and McDonald Islands</option>
            <option value="Honduras">Honduras</option>
            <option value="Croatia">Croatia</option>
            <option value="Haiti">Haiti</option>
            <option value="Hungary">Hungary</option>
            <option value="Indonesia">Indonesia</option>
            <option value="Isle of Man">Isle of Man</option>
            <option value="India">India</option>
            <option value="British Indian Ocean Territory">British Indian Ocean Territory</option>
            <option value="Ireland">Ireland</option>
            <option value="Iran, Islamic Republic of">Iran, Islamic Republic of</option>
            <option value="Iraq">Iraq</option>
            <option value="Iceland">Iceland</option>
            <option value="Israel">Israel</option>
            <option value="Italy">Italy</option>
            <option value="Jamaica">Jamaica</option>
            <option value="Jersey">Jersey</option>
            <option value="Jordan">Jordan</option>
            <option value="Japan">Japan</option>
            <option value="Kazakhstan">Kazakhstan</option>
            <option value="Kenya">Kenya</option>
            <option value="Kyrgyzstan">Kyrgyzstan</option>
            <option value="Cambodia">Cambodia</option>
            <option value="Kiribati">Kiribati</option>
            <option value="Saint Kitts and Nevis">Saint Kitts and Nevis</option>
            <option value="Korea, Republic of">Korea, Republic of</option>
            <option value="Kuwait">Kuwait</option>
            <option value="Lao People's Democratic Republic">Lao People's Democratic Republic</option>
            <option value="Lebanon">Lebanon</option>
            <option value="Liberia">Liberia</option>
            <option value="Libya">Libya</option>
            <option value="Saint Lucia">Saint Lucia</option>
            <option value="Liechtenstein">Liechtenstein</option>
            <option value="Sri Lanka">Sri Lanka</option>
            <option value="Lesotho">Lesotho</option>
            <option value="Lithuania">Lithuania</option>
            <option value="Luxembourg">Luxembourg</option>
            <option value="Latvia">Latvia</option>
            <option value="Macao">Macao</option>
            <option value="Saint Martin (French part)">Saint Martin (French part)</option>
            <option value="Morocco">Morocco</option>
            <option value="Monaco">Monaco</option>
            <option value="Moldova, Republic of">Moldova, Republic of</option>
            <option value="Madagascar">Madagascar</option>
            <option value="Maldives">Maldives</option>
            <option value="Mexico">Mexico</option>
            <option value="Marshall Islands">Marshall Islands</option>
            <option value="Macedonia, the former Yugoslav Republic of">Macedonia, the former Yugoslav Republic of</option>
            <option value="Mali">Mali</option>
            <option value="Malta">Malta</option>
            <option value="Myanmar">Myanmar</option>
            <option value="Montenegro">Montenegro</option>
            <option value="Mongolia">Mongolia</option>
            <option value="Northern Mariana Islands">Northern Mariana Islands</option>
            <option value="Mozambique">Mozambique</option>
            <option value="Mauritania">Mauritania</option>
            <option value="Montserrat">Montserrat</option>
            <option value="Martinique">Martinique</option>
            <option value="Mauritius">Mauritius</option>
            <option value="Malawi">Malawi</option>
            <option value="Malaysia">Malaysia</option>
            <option value="Mayotte">Mayotte</option>
            <option value="Namibia">Namibia</option>
            <option value="New Caledonia">New Caledonia</option>
            <option value="Niger">Niger</option>
            <option value="Norfolk Island">Norfolk Island</option>
            <option value="Nigeria">Nigeria</option>
            <option value="Nicaragua">Nicaragua</option>
            <option value="Niue">Niue</option>
            <option value="Netherlands">Netherlands</option>
            <option value="Norway">Norway</option>
            <option value="Nepal">Nepal</option>
            <option value="Nauru">Nauru</option>
            <option value="New Zealand">New Zealand</option>
            <option value="Oman">Oman</option>
            <option value="Pakistan">Pakistan</option>
            <option value="Panama">Panama</option>
            <option value="Pitcairn">Pitcairn</option>
            <option value="Peru">Peru</option>
            <option value="Philippines">Philippines</option>
            <option value="Palau">Palau</option>
            <option value="Papua New Guinea">Papua New Guinea</option>
            <option value="Poland">Poland</option>
            <option value="Puerto Rico">Puerto Rico</option>
            <option value="Korea, Democratic People's Republic of">Korea, Democratic People's Republic of</option>
            <option value="Portugal">Portugal</option>
            <option value="Paraguay">Paraguay</option>
            <option value="Palestine, State of">Palestine, State of</option>
            <option value="French Polynesia">French Polynesia</option>
            <option value="Qatar">Qatar</option>
            <option value="Réunion">Réunion</option>
            <option value="Romania">Romania</option>
            <option value="Russian Federation">Russian Federation</option>
            <option value="Rwanda">Rwanda</option>
            <option value="Saudi Arabia">Saudi Arabia</option>
            <option value="Sudan">Sudan</option>
            <option value="Senegal">Senegal</option>
            <option value="Singapore">Singapore</option>
            <option value="South Georgia and the South Sandwich Islands">South Georgia and the South Sandwich Islands</option>
            <option value="Saint Helena, Ascension and Tristan da Cunha">Saint Helena, Ascension and Tristan da Cunha</option>
            <option value="Svalbard and Jan Mayen">Svalbard and Jan Mayen</option>
            <option value="Solomon Islands">Solomon Islands</option>
            <option value="Sierra Leone">Sierra Leone</option>
            <option value="El Salvador">El Salvador</option>
            <option value="San Marino">San Marino</option>
            <option value="Somalia">Somalia</option>
            <option value="Saint Pierre and Miquelon">Saint Pierre and Miquelon</option>
            <option value="Serbia">Serbia</option>
            <option value="South Sudan">South Sudan</option>
            <option value="Sao Tome and Principe">Sao Tome and Principe</option>
            <option value="Suriname">Suriname</option>
            <option value="Slovakia">Slovakia</option>
            <option value="Slovenia">Slovenia</option>
            <option value="Sweden">Sweden</option>
            <option value="Swaziland">Swaziland</option>
            <option value="Sint Maarten (Dutch part)">Sint Maarten (Dutch part)</option>
            <option value="Seychelles">Seychelles</option>
            <option value="Syrian Arab Republic">Syrian Arab Republic</option>
            <option value="Turks and Caicos Islands">Turks and Caicos Islands</option>
            <option value="Chad">Chad</option>
            <option value="Togo">Togo</option>
            <option value="Thailand">Thailand</option>
            <option value="Tajikistan">Tajikistan</option>
            <option value="Tokelau">Tokelau</option>
            <option value="Turkmenistan">Turkmenistan</option>
            <option value="Timor-Leste">Timor-Leste</option>
            <option value="Tonga">Tonga</option>
            <option value="Trinidad and Tobago">Trinidad and Tobago</option>
            <option value="Tunisia">Tunisia</option>
            <option value="Turkey">Turkey</option>
            <option value="Tuvalu">Tuvalu</option>
            <option value="Taiwan, Province of China">Taiwan, Province of China</option>
            <option value="Tanzania, United Republic of">Tanzania, United Republic of</option>
            <option value="Uganda">Uganda</option>
            <option value="Ukraine">Ukraine</option>
            <option value="United States Minor Outlying Islands">United States Minor Outlying Islands</option>
            <option value="Uruguay">Uruguay</option>
            <option value="United States">United States</option>
            <option value="Uzbekistan">Uzbekistan</option>
            <option value="Holy See (Vatican City State)">Holy See (Vatican City State)</option>
            <option value="Saint Vincent and the Grenadines">Saint Vincent and the Grenadines</option>
            <option value="Venezuela, Bolivarian Republic of">Venezuela, Bolivarian Republic of</option>
            <option value="Virgin Islands, British">Virgin Islands, British</option>
            <option value="Virgin Islands, U.S.">Virgin Islands, U.S.</option>
            <option value="Viet Nam">Viet Nam</option>
            <option value="Vanuatu">Vanuatu</option>
            <option value="Wallis and Futuna">Wallis and Futuna</option>
            <option value="Samoa">Samoa</option>
            <option value="Yemen">Yemen</option>
            <option value="South Africa">South Africa</option>
            <option value="Zambia">Zambia</option>
            <option value="Zimbabwe">Zimbabwe</option>
          </select></div>
        <div class="selectric"><span class="label">—Please choose an option—</span><b class="button"></b></div>
        <div class="selectric-items" tabindex="-1">
          <div class="selectric-scroll">
            <ul>
              <li data-index="0" class="selected">—Please choose an option—</li>
              <li data-index="1" class="">Aruba</li>
              <li data-index="2" class="">Afghanistan</li>
              <li data-index="3" class="">Angola</li>
              <li data-index="4" class="">Anguilla</li>
              <li data-index="5" class="">Åland Islands</li>
              <li data-index="6" class="">Albania</li>
              <li data-index="7" class="">Andorra</li>
              <li data-index="8" class="">United Arab Emirates</li>
              <li data-index="9" class="">Argentina</li>
              <li data-index="10" class="">Armenia</li>
              <li data-index="11" class="">American Samoa</li>
              <li data-index="12" class="">Antarctica</li>
              <li data-index="13" class="">French Southern Territories</li>
              <li data-index="14" class="">Antigua and Barbuda</li>
              <li data-index="15" class="">Australia</li>
              <li data-index="16" class="">Austria</li>
              <li data-index="17" class="">Azerbaijan</li>
              <li data-index="18" class="">Burundi</li>
              <li data-index="19" class="">Belgium</li>
              <li data-index="20" class="">Benin</li>
              <li data-index="21" class="">Bonaire, Sint Eustatius and Saba</li>
              <li data-index="22" class="">Burkina Faso</li>
              <li data-index="23" class="">Bangladesh</li>
              <li data-index="24" class="">Bulgaria</li>
              <li data-index="25" class="">Bahrain</li>
              <li data-index="26" class="">Bahamas</li>
              <li data-index="27" class="">Bosnia and Herzegovina</li>
              <li data-index="28" class="">Saint Barthélemy</li>
              <li data-index="29" class="">Belarus</li>
              <li data-index="30" class="">Belize</li>
              <li data-index="31" class="">Bermuda</li>
              <li data-index="32" class="">Bolivia, Plurinational State of</li>
              <li data-index="33" class="">Brazil</li>
              <li data-index="34" class="">Barbados</li>
              <li data-index="35" class="">Brunei Darussalam</li>
              <li data-index="36" class="">Bhutan</li>
              <li data-index="37" class="">Bouvet Island</li>
              <li data-index="38" class="">Botswana</li>
              <li data-index="39" class="">Central African Republic</li>
              <li data-index="40" class="">Canada</li>
              <li data-index="41" class="">Cocos (Keeling) Islands</li>
              <li data-index="42" class="">Switzerland</li>
              <li data-index="43" class="">Chile</li>
              <li data-index="44" class="">China</li>
              <li data-index="45" class="">Côte d'Ivoire</li>
              <li data-index="46" class="">Cameroon</li>
              <li data-index="47" class="">Congo, the Democratic Republic of the</li>
              <li data-index="48" class="">Congo</li>
              <li data-index="49" class="">Cook Islands</li>
              <li data-index="50" class="">Colombia</li>
              <li data-index="51" class="">Comoros</li>
              <li data-index="52" class="">Cape Verde</li>
              <li data-index="53" class="">Costa Rica</li>
              <li data-index="54" class="">Cuba</li>
              <li data-index="55" class="">Curaçao</li>
              <li data-index="56" class="">Christmas Island</li>
              <li data-index="57" class="">Cayman Islands</li>
              <li data-index="58" class="">Cyprus</li>
              <li data-index="59" class="">Czech Republic</li>
              <li data-index="60" class="">Germany</li>
              <li data-index="61" class="">Djibouti</li>
              <li data-index="62" class="">Dominica</li>
              <li data-index="63" class="">Denmark</li>
              <li data-index="64" class="">Dominican Republic</li>
              <li data-index="65" class="">Algeria</li>
              <li data-index="66" class="">Ecuador</li>
              <li data-index="67" class="">Egypt</li>
              <li data-index="68" class="">Eritrea</li>
              <li data-index="69" class="">Western Sahara</li>
              <li data-index="70" class="">Spain</li>
              <li data-index="71" class="">Estonia</li>
              <li data-index="72" class="">Ethiopia</li>
              <li data-index="73" class="">Finland</li>
              <li data-index="74" class="">Fiji</li>
              <li data-index="75" class="">Falkland Islands (Malvinas)</li>
              <li data-index="76" class="">France</li>
              <li data-index="77" class="">Faroe Islands</li>
              <li data-index="78" class="">Micronesia, Federated States of</li>
              <li data-index="79" class="">Gabon</li>
              <li data-index="80" class="">United Kingdom</li>
              <li data-index="81" class="">Georgia</li>
              <li data-index="82" class="">Guernsey</li>
              <li data-index="83" class="">Ghana</li>
              <li data-index="84" class="">Gibraltar</li>
              <li data-index="85" class="">Guinea</li>
              <li data-index="86" class="">Guadeloupe</li>
              <li data-index="87" class="">Gambia</li>
              <li data-index="88" class="">Guinea-Bissau</li>
              <li data-index="89" class="">Equatorial Guinea</li>
              <li data-index="90" class="">Greece</li>
              <li data-index="91" class="">Grenada</li>
              <li data-index="92" class="">Greenland</li>
              <li data-index="93" class="">Guatemala</li>
              <li data-index="94" class="">French Guiana</li>
              <li data-index="95" class="">Guam</li>
              <li data-index="96" class="">Guyana</li>
              <li data-index="97" class="">Hong Kong</li>
              <li data-index="98" class="">Heard Island and McDonald Islands</li>
              <li data-index="99" class="">Honduras</li>
              <li data-index="100" class="">Croatia</li>
              <li data-index="101" class="">Haiti</li>
              <li data-index="102" class="">Hungary</li>
              <li data-index="103" class="">Indonesia</li>
              <li data-index="104" class="">Isle of Man</li>
              <li data-index="105" class="">India</li>
              <li data-index="106" class="">British Indian Ocean Territory</li>
              <li data-index="107" class="">Ireland</li>
              <li data-index="108" class="">Iran, Islamic Republic of</li>
              <li data-index="109" class="">Iraq</li>
              <li data-index="110" class="">Iceland</li>
              <li data-index="111" class="">Israel</li>
              <li data-index="112" class="">Italy</li>
              <li data-index="113" class="">Jamaica</li>
              <li data-index="114" class="">Jersey</li>
              <li data-index="115" class="">Jordan</li>
              <li data-index="116" class="">Japan</li>
              <li data-index="117" class="">Kazakhstan</li>
              <li data-index="118" class="">Kenya</li>
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B-HAPOE4 MICE

Home In vivo Animal and Cell Models Other Humanized Models B-hAPOE4 mice

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BASIC INFORMATION

Strain Name
C57BL/6JNifdc-Apoetm1(APOE*4)/Bcgen
Common Name
B-hAPOE4 mice
Background
C57BL/6JNifdc
Catalog Number
112564
NCBI Gene ID
916 ;10683
Related Genes
APOE: AD2, LPG, APO-E, LDLCQ5


TARGETING STRATEGY

Gene targeting strategy for B-hAPOE4 mice.
The exons 2~4 of mouse Apoe gene that encode the full-length protein were
replaced by human APOE4 exons 2~4 in B-hAPOE4 mice.


PROTEIN EXPRESSION ANALYSIS IN SERUM

Strain specific APOE expression analysis in homozygous B-hAPOE4 mice by ELISA.
Serum collected from wild-type C57BL/6JNifdc mice (+/+) and homozygous B-hAPOE4
mice (H/H) were analyzed by ELISA with species-specific APOE ELISA kit. Mouse
APOE was detectable in wild-type mice (A). Human APOE was exclusively detectable
in homozygous B-hAPOE4 mice but not in wild-type mice (B).


PROTEIN EXPRESSION ANALYSIS IN BRAIN

Strain specific APOE expression analysis in homozygous B-hAPOE4 mice by ELISA.
Brain collected from wild-type C57BL/6JNifdc mice (+/+) and homozygous B-hAPOE4
mice (H/H) were extracted and APOE was measured in the brain homogenates using
species-specific APOE ELISA kit and then normalized to total protein levels.
Mouse APOE was detectable in wild-type mice (A). Human APOE was exclusively
detectable in homozygous B-hAPOE4 mice but not in wild-type mice (B).


MRNA EXPRESSION ANALYSIS

Strain specific analysis of APOE4 mRNA expression in wild-type C57BL/6J mice and
B-hAPOE4 mice by RT-PCR. Liver RNA were isolated from wild-type C57BL/6JNifdc
mice (+/+) and homozygous B-hAPOE4 mice (H/H), then cDNA libraries were
synthesized by reverse transcription, followed by PCR with mouse or human APOE
primers. Mouse Apoe mRNA was detectable only in wild-type mice. Human APOE4 mRNA
was detectable only in homozygous B-hAPOE4 mice but not in wild-type mice. And
the results were confirmed via Sanger sequencing.


SUMMARY

mRNA expression analysis:
Mouse Apoe mRNA was detectable in liver of wild-type C57BL/6JNfidc mice. Human
APOE4 mRNA was detectable in B-hAPOE4 mice and was confirmed via Sanger
sequencing.

Protein expression analysis:
Human APOE4 was both detectable in serum and brain from homozygous B-hAPOE4
mice, and mouse APOE was detectable only in wild-type C57BL/6JNfidc mice.

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