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HEALTH PREDISPOSITIONS*LEARN ABOUT CONSIDERATIONS AND LIMITATIONS FOR HEALTH
PREDISPOSITIONS REPORTS, CARRIER STATUS REPORTS AND GENETIC HEALTH RISKS
Our DNA testing can help you learn how genetics can influence your chances of
developing certain health conditions.
Phone Slide 0: Health Predispositions*Learn about Considerations and Limitations
for Health Predispositions Reports, Carrier Status Reports and Genetic Health
RisksPhone Slide 1: Carrier Status*Learn about Considerations and Limitations
for Health Predispositions Reports, Carrier Status Reports and Genetic Health
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ANCESTRY COMPOSITION
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PHYSICAL FEATURES
Discover what makes you unique. With reports like hair photobleaching and
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Phone Slide 0: Physical FeaturesPhone Slide 1: Taste and SmellPhone Slide 2:
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Ancestry Reports
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Trait reports
Learn how your DNA influences your facial features, taste, smell and other
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Health Predisposition reports*Learn about Considerations and Limitations for
Health Predispositions Reports, Carrier Status Reports and Genetic Health Risks
Learn how your genetics can influence your chances of developing certain health
conditions.
Carrier Status reports*Learn about Considerations and Limitations for Health
Predispositions Reports, Carrier Status Reports and Genetic Health Risks
If you are starting a family, find out if you are a carrier for certain
inherited conditions.
Wellness reports
Learn how your genes play a role in your well-being and lifestyle choices.
Pharmacogenetics reports**Learn about Considerations and Limitations for
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Discover how your DNA may impact how your body processes certain medications
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FREQUENTLY ASKED QUESTIONS
How accurate is 23andMe?
23andMe has rigorous standards that ensure high-quality results. Our team of
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for our customers. Here are specific examples:
* With one of the largest reference datasets in the world, 23andMe provides
customers with one of the most detailed and accurate ancestry breakdowns on
the market. Our algorithms make ancestry estimates based on probabilities and
they’re generally very accurate, but your results are not set in stone. We
are always trying to improve and refine these estimates.
* Our Genetic Health Risk*Learn about Considerations and Limitations for Health
Predispositions Reports, Carrier Status Reports and Genetic Health Risks,
Carrier Status*Learn about Considerations and Limitations for Health
Predispositions Reports, Carrier Status Reports and Genetic Health Risks,
Pharmacogenetics**Learn about Considerations and Limitations for
Pharmacogenetics Reports reports meet FDA requirements. This means that each
variant in those reports demonstrated >greater than99% accuracy and
reproducibility when tested under different laboratory conditions. This
article on the accuracy of 23andMe reports provides additional information.
How does 23andMe DNA testing work?
After you provide a saliva sample, 23andMe uses genotyping to analyze your DNA.
This means we look at specific locations in your genome that are known to differ
between people. We then turn those results into personalized genetic reports on
everything from ancestry composition to traits to genetic health risks. Note
that genotyping is different from DNA sequencing, which looks at every letter in
a particular stretch of DNA.
Who can use 23andMe?
Most adults who are able to provide saliva samples can use the 23andMe kit.
However there are some considerations that can complicate the DNA accuracy.
Check out our Terms of Service for more info on those cases.
How do I get my 23andMe reports and how long does it take?
To begin, visit www.23andme.com/start. Once you have successfully registered
your DNA testing kit, provided a saliva sample and put the kit in the mail, you
can use the return tracking link available on your profile homepage to track
your kit's progress to the lab. Once your sample reaches the lab, it is
typically processed within a few weeks, with results then delivered to your
secure online account.
Do 23andMe DNA test kits expire?
We encourage customers to provide their sample before the "Collect saliva by"
date on the side of the collection tube. If your sample collection kit is lost
or damaged, or if it has expired, please contact customer care to assist you
with getting a replacement kit.
Why should I choose 23andMe?
There are many benefits of DNA testing, including finding relatives, learning
whether you have genetic variants you could pass onto your children, and
receiving personalized insights into your health and ancestry. 23andMe Health +
Ancestry Service offers 150+ DNA reports that do just that. In addition to
taking greater control of your own health and digging deeper into your ancestry,
you can also opt in to participate in research that could help fuel scientific
discoveries that benefit the larger community.
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*The 23andMe PGS test includes health predisposition and carrier status reports.
Health predisposition reports include both reports that meet FDA requirements
for genetic health risks and reports which are based on 23andMe research and
have not been reviewed by the FDA. The test uses qualitative genotyping to
detect select clinically relevant variants in the genomic DNA of adults from
saliva for the purpose of reporting and interpreting genetic health risks and
reporting carrier status. It is not intended to diagnose any disease. Your
ethnicity may affect the relevance of each report and how your genetic health
risk results are interpreted. Each genetic health risk report describes if a
person has variants associated with a higher risk of developing a disease, but
does not describe a person’s overall risk of developing the disease. The test is
not intended to tell you anything about your current state of health, or to be
used to make medical decisions, including whether or not you should take a
medication, how much of a medication you should take, or determine any
treatment. Our carrier status reports can be used to determine carrier status,
but cannot determine if you have two copies of any genetic variant. These
carrier reports are not intended to tell you anything about your risk for
developing a disease in the future, the health of your fetus, or your newborn
child's risk of developing a particular disease later in life. For certain
conditions, we provide a single report that includes information on both carrier
status and genetic health risk. Warnings & Limitations: The 23andMe PGS Genetic
Health Risk Report for BRCA1/BRCA2 (Selected Variants) is indicated for
reporting of the 185delAG and 5382insC variants in the BRCA1 gene and the
6174delT variant in the BRCA2 gene. The report describes if a woman is at
increased risk of developing breast and ovarian cancer, and if a man is at
increased risk of developing breast cancer or may be at increased risk of
developing prostate cancer. The three variants included in this report are most
common in people of Ashkenazi Jewish descent and do not represent the majority
of BRCA1/BRCA2 variants in the general population. This report does not include
variants in other genes linked to hereditary cancers and the absence of variants
included in this report does not rule out the presence of other genetic variants
that may impact cancer risk. The PGS test is not a substitute for visits to a
healthcare professional for recommended screenings or appropriate follow-up.
Results should be confirmed in a clinical setting before taking any medical
action. For important information and limitations regarding each genetic health
risk and carrier status report, visit 23andme.com/test-info/
**23andMe PGS Pharmacogenetics reports: The 23andMe test uses qualitative
genotyping to detect 3 variants in the CYP2C19 gene, 2 variants in the DPYD gene
and 1 variant in the SLCO1B1 gene in the genomic DNA of adults from saliva for
the purpose of reporting and interpreting information about the processing of
certain therapeutics to inform discussions with a healthcare professional. It
does not describe if a person will or will not respond to a particular
therapeutic and does not describe the association between detected variants and
any specific therapeutic. Our CYP2C19 Pharmacogenetics report provides certain
information about variants associated with metabolism of some therapeutics and
provides interpretive drug information regarding the potential effect of
citalopram and clopidogrel therapy. Results for SLCO1B1 and DPYD and certain
CYP2C19 results should be confirmed by an independent genetic test prescribed by
your own healthcare provider before taking any medical action. Warning: Test
information should not be used to start, stop, or change any course of treatment
and does not test for all possible variants that may affect metabolism or
protein function. The PGS test is not a substitute for visits to a healthcare
professional. Making changes to your current regimen can lead to harmful side
effects or reduced intended benefits of your medication, therefore consult with
your healthcare professional before taking any medical action. For important
information and limitations regarding Pharmacogenetics reports, visit
23andme.com/test-info/pharmacogenetics/
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