www.alunbrig.com
Open in
urlscan Pro
23.185.0.4
Public Scan
Submitted URL: https://alunbrig.us/
Effective URL: https://www.alunbrig.com/
Submission: On April 04 via api from US — Scanned from US
Effective URL: https://www.alunbrig.com/
Submission: On April 04 via api from US — Scanned from US
Form analysis 0 forms found in the DOM
Text Content
* skip to Main Content
This site is intended for US patients only.
* Important Safety Information
* Patient Information
* Prescribing Information
* Healthcare Professional Site
Menu Close
* What is ALK+ NSCLC?
* What is ALUNBRIG?
* Study Results
* Newly Diagnosed
* After Crizotinib
* Taking ALUNBRIG
* Side Effects
* Important Resources
* Useful Resources
* SMART Free Trial Program
* Takeda Oncology Here2Assist®
* Stay Connected
LEARN ABOUT TREATMENT WITH ALUNBRIG® (BRIGATINIB) FOR ALK+ METASTATIC NON-SMALL
CELL LUNG CANCER (MNSCLC)
Discover Alunbrig
IF YOU ARE NEWLY DIAGNOSED
Discover More
AFTER TREATMENT WITH CRIZOTINIB
Learn More
IMPORTANT RESOURCES FOR YOU
Explore More
Video Player is loading.
Play Video
Play
Mute
Current Time 0:00
/
Duration 12:09
Loaded: 1.35%
00:00
Stream Type LIVE
Seek to live, currently behind liveLIVE
Remaining Time -12:09
1x
Playback Rate
Chapters
* Chapters
Descriptions
* descriptions off, selected
Captions
* captions settings, opens captions settings dialog
* captions off, selected
Audio Track
* en (Main), selected
Picture-in-PictureFullscreen
This is a modal window.
Beginning of dialog window. Escape will cancel and close the window.
TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaque
Font Size50%75%100%125%150%175%200%300%400%Text Edge
StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional
Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall
Caps
Reset restore all settings to the default valuesDone
Close Modal Dialog
End of dialog window.
Close Modal Dialog
This is a modal window. This modal can be closed by pressing the Escape key or
activating the close button.
This is a modal window.
RestartShare
ERIC & MEGHAN'S STORY
Learn about how Eric and Meghan have navigated Eric’s ALK+ mNSCLC diagnosis,
their experience with ALUNBRIG, and how together they are living with lung
cancer.
Eric is a real ALUNBRIG patient
ViewHide Transcript
[Meghan]
Eric and I have been married for about 10 years, we have a pretty vibrant life.
A lung cancer diagnosis made no sense to us.
Often people say it's like having the rug pulled out from underneath you, when
you get a diagnosis like that. I correct them. And I say it's like the whole
floor, coming out from underneath you.
When we got that phone call or news from the physician of his cancer diagnosis,
I knew it would be a major inflection point in our life.
[Eric]
Prior to diagnosis, my health started to change in such a way that I was having
difficulty breathing. And I was coughing quite a bit.
The symptoms that I had, definitely felt like someone standing on my chest. I
was also having difficulty sleeping on my back, which led me to a lot more
sleepless nights.
It came up in a conversation with my wife and after she said, “Hey, I'm
concerned that your coughing is becoming uncontrollable. I think it's time for
you to visit your primary care physician.”
It was a very short period of time, I was able to go from an x-ray to a CT in
the same day. And then within two days, I was doing a biopsy.
The first time that I heard the word cancer, from my physician. I will never
forget those words.
At age 41. I was diagnosed with stage four ALK positive non-small cell lung
cancer. Receiving a diagnosis of this sort, made no sense to me.
[Meghan]
We've obviously subsequently learned that anyone with lungs can get lung cancer.
[Eric]
It took me a while to understand the impact of having brain metastases. And at
that point, I was honestly so defeated and downtrodden.
As my treatment options were explained to me, I had the choice of a few
different TKIs. I consulted with my family, my oncologists and other primary
care specialists to pick the best option for me based on the side effects and
the dosing. And for me, that choice was ALUNBRIG.
ALUNBRIG is a prescription medicine used to treat adults with non-small cell
lung cancer, NSCLC, that has a certain type of abnormal anaplastic lymphoma
kinase, ALK, gene and that has spread to other parts of your body. It is not
known if ALUNBRIG is safe and effective in children.
The most important factor when selecting ALUNBRIG was how it would impact my
life. And I looked at the side effects and the dosage. And those two combined,
made it feel that it would be the least impactful to my everyday life.
I've experienced bradycardia nausea and stomach pain while taking ALUNBRIG. But
these are not all of the possible side effects. And everyone is different.
Speak to your healthcare provider about all the potential side effects with
ALUNBRIG.
[Meghan]
The treatment was very easy to incorporate into our lives. Being able to take
one pill a day was of a significant benefit to him as well.
[Eric]
I started ALUNBRIG on the seven-day starter dosage of 90 milligrams, after which
I increased to 180 milligrams, which I currently take.
[Meghan]
From my perspective, Eric has responded really well to ALUNBRIG.
Fortunately, it had a rapid reduction in his tumor volume. He was able to
tolerate the medicine.
[Eric]
After reading my scan reports, one of the terms frequently used is
“unremarkable”. That effectively means that while my tumors are still present,
they're not growing or spreading. So, I will happily claim to be an
“unremarkable cancer patient”.
[Meghan]
When Eric was first diagnosed with lung cancer, he was given a prognosis of nine
to 12 months. That timing then aligned with our 10-year wedding anniversary. So,
our goal became to make it to the anniversary.
And as we did, we elected to have a vow renewal ceremony with a number of family
and friends.
We're able to take less of the focus on his treatment and the worry and put it
more so into creating memories together.
[Eric]
The best piece of advice that I've received from my care is that you don't have
to hit a homerun your first at bat. You have to get on base. You have to stay
healthy enough to take advantage of technology and its advances.
And that's what gives me hope.
SIGN UP NOW TO RECEIVE USEFUL INFORMATION AND UPDATES ABOUT ALUNBRIG.
REGISTER FOR UPDATES
IMPORTANT SAFETY INFORMATION, INDICATION, AND USAGE
Expand+
ALUNBRIG CAN CAUSE SERIOUS SIDE EFFECTS, INCLUDING:
* Lung problems. ALUNBRIG may cause severe or life-threatening swelling
(inflammation) of the lungs any time during treatment and can lead to death.
These lung problems happen especially within the first week of treatment with
ALUNBRIG. Symptoms may be similar to those symptoms from lung cancer. Tell
your healthcare provider right away if you have any new or worsening
symptoms. including:
* trouble breathing or shortness of breath
* chest pain
* cough with or without mucus
* fever
* High blood pressure (hypertension). ALUNBRIG may cause high blood pressure.
Your healthcare provider will check your blood pressure before starting and
during treatment with ALUNBRIG. Tell your healthcare provider right away if
you get headaches, dizziness, blurred vision, chest pain or shortness of
breath.
* Slow heart rate (bradycardia). ALUNBRIG may cause very slow heartbeats that
can be severe. Your healthcare provider will check your heart rate during
treatment with ALUNBRIG. Tell your healthcare provider right away if you feel
dizzy, lightheaded, or faint during treatment with ALUNBRIG. Tell your
healthcare provider if you take any heart or blood pressure medicines.
* Vision problems. ALUNBRIG may cause vision problems. Your healthcare provider
may stop ALUNBRIG and refer you to an eye specialist if you develop severe
vision problems during treatment with ALUNBRIG. Tell your healthcare provider
right away if you have any loss of vision or any change in vision, including:
* double vision
* seeing flashes of light
* blurry vision
* light hurting your eyes
* new or increased floaters
* Muscle pain, tenderness, and weakness (myalgia). ALUNBRIG may increase the
level of an enzyme in your blood called creatine phosphokinase (CPK), which
may be a sign of muscle damage. Your healthcare provider will do blood tests
to check your blood levels of CPK during treatment with ALUNBRIG. Tell your
healthcare provider right away if you get new or worsening signs and symptoms
of muscle problems, including unexplained muscle pain or muscle pain that
does not go away, tenderness, or weakness.
* Inflammation of the pancreas (pancreatitis). ALUNBRIG may increase enzymes in
your blood called amylase and lipase, which may be a sign of pancreatitis.
Your healthcare provider will do blood tests to check your pancreatic enzyme
blood levels during treatment with ALUNBRIG. Tell your healthcare provider
right away if you get new or worsening signs and symptoms of pancreatitis,
including upper abdominal pain that may spread to the back and get worse with
eating, weight loss, or nausea.
* Liver problems (hepatotoxicity). ALUNBRIG may increase the levels of
bilirubin in your blood and enzymes called aspartate aminotransferase (AST)
and alanine aminotransferase (ALT) in your blood, which may be a sign of
liver problems. Your healthcare provider will do blood tests to check your
liver during treatment with ALUNBRIG. Tell your healthcare provider right
away if you get new or worsening signs or symptoms, including:
* yellowing of your skin or the white part of your eyes
* dark or brown (tea color) urine
* nausea or vomiting
* pain on the right side of your stomach area
* bleed or bruise more easily than normal
* itchy skin
* decreased appetite
* feeling tired
* High blood sugar (hyperglycemia). ALUNBRIG may increase your blood sugar
levels. Your healthcare provider will do blood tests to check your blood
sugar levels before starting and during treatment with ALUNBRIG. Your
healthcare provider may need to start or change your blood sugar medicine to
control your blood sugar levels. Tell your healthcare provider right away if
you get new or worsening signs and symptoms of hyperglycemia, including:
* feeling very thirsty
* needing to urinate more than usual
* feeling very hungry
* feeling sick to your stomach
* feeling weak or tired
* feeling confused
The most common side effects of ALUNBRIG include diarrhea, fatigue, nausea,
rash, cough, muscle pain, headache, high blood pressure, vomiting and difficulty
breathing.
ALUNBRIG may cause fertility problems in males. This may affect your ability to
father a child. Talk to your healthcare provider if you have concerns about
fertility.
These are not all the possible side effects of ALUNBRIG. Call your doctor for
medical advice about side effects. You may report side effects to the FDA at
1-800-FDA-1088.
WHAT SHOULD I AVOID WHILE TAKING ALUNBRIG?
* Limit your time in the sun during treatment with ALUNBRIG and for at least 5
days after your final dose. ALUNBRIG may make your skin sensitive to
sunlight. You may burn more easily and get severe sunburns. When you are in
the sun, wear a hat and protective clothing, and use a broad-spectrum
sunscreen and lip balm with a Sun Protection Factor (SPF) of 30 or greater to
protect against sunburn.
* Avoid eating grapefruit or drinking grapefruit juice during treatment with
ALUNBRIG. Grapefruit may increase the amount of ALUNBRIG in your blood.
Before you take ALUNBRIG, tell your healthcare provider about all of your
medical conditions, including if you have lung or breathing problems, high blood
pressure, a slow heartbeat, or any vision problems, have or have had
pancreatitis, have liver problems, have diabetes mellitus or glucose
intolerance, have kidney problems or are on dialysis, are pregnant or plan to
become pregnant, or are breastfeeding or plan to breastfeed.
* ALUNBRIG can harm your unborn baby. Your healthcare provider will determine
whether or not you are pregnant before you start treatment with ALUNBRIG.
Tell your healthcare provider right away if you become pregnant during
treatment with ALUNBRIG or think you may be pregnant.
* Females who are able to become pregnant should use effective birth control
during treatment with ALUNBRIG and for at least 4 months after the final
dose of ALUNBRIG. Talk to your healthcare provider about birth control
choices that are right for you during treatment with ALUNBRIG.
* Males who have female partners who are able to become pregnant should use
effective birth control during treatment with ALUNBRIG and for at least 3
months after the final dose of ALUNBRIG.
* It is not known if ALUNBRIG passes into your breast milk. Do not breastfeed
during treatment with ALUNBRIG and for 1 week after the final dose of
ALUNBRIG.
Tell your healthcare provider about all the medicines you take, including
prescription medicines, over-the-counter medicines, vitamins, or herbal
supplements.
Please read the Patient Information in the full Prescribing Information and
discuss with your healthcare provider.
WHAT IS ALUNBRIG?
ALUNBRIG is a prescription medicine used to treat adults with non-small cell
lung cancer (NSCLC):
* that has a certain type of abnormal anaplastic lymphoma kinase (ALK) gene,
and
* that has spread to other parts of your body
It is not known if ALUNBRIG is safe and effective in children.
IMPORTANT SAFETY INFORMATION
ALUNBRIG CAN CAUSE SERIOUS SIDE EFFECTS, INCLUDING:
* Lung problems. ALUNBRIG may cause severe or life-threatening swelling
(inflammation) of the lungs any time during treatment and can lead to death.
These lung problems happen especially within the first week of treatment with
ALUNBRIG. Symptoms may be similar to those symptoms from lung cancer. Tell
your healthcare provider right away if you have any new or worsening
symptoms. including:
* trouble breathing or shortness of breath
* chest pain
* cough with or without mucus
* fever
* High blood pressure (hypertension). ALUNBRIG may cause high blood pressure.
Your healthcare provider will check your blood pressure before starting and
during treatment with ALUNBRIG. Tell your healthcare provider right away if
you get headaches, dizziness, blurred vision, chest pain or shortness of
breath.
* Slow heart rate (bradycardia). ALUNBRIG may cause very slow heartbeats that
can be severe. Your healthcare provider will check your heart rate during
treatment with ALUNBRIG. Tell your healthcare provider right away if you feel
dizzy, lightheaded, or faint during treatment with ALUNBRIG. Tell your
healthcare provider if you take any heart or blood pressure medicines.
* Vision problems. ALUNBRIG may cause vision problems. Your healthcare provider
may stop ALUNBRIG and refer you to an eye specialist if you develop severe
vision problems during treatment with ALUNBRIG. Tell your healthcare provider
right away if you have any loss of vision or any change in vision, including:
* double vision
* seeing flashes of light
* blurry vision
* light hurting your eyes
* new or increased floaters
* Muscle pain, tenderness, and weakness (myalgia). ALUNBRIG may increase the
level of an enzyme in your blood called creatine phosphokinase (CPK), which
may be a sign of muscle damage. Your healthcare provider will do blood tests
to check your blood levels of CPK during treatment with ALUNBRIG. Tell your
healthcare provider right away if you get new or worsening signs and symptoms
of muscle problems, including unexplained muscle pain or muscle pain that
does not go away, tenderness, or weakness.
* Inflammation of the pancreas (pancreatitis). ALUNBRIG may increase enzymes in
your blood called amylase and lipase, which may be a sign of pancreatitis.
Your healthcare provider will do blood tests to check your pancreatic enzyme
blood levels during treatment with ALUNBRIG. Tell your healthcare provider
right away if you get new or worsening signs and symptoms of pancreatitis,
including upper abdominal pain that may spread to the back and get worse with
eating, weight loss, or nausea.
* Liver problems (hepatotoxicity). ALUNBRIG may increase the levels of
bilirubin in your blood and enzymes called aspartate aminotransferase (AST)
and alanine aminotransferase (ALT) in your blood, which may be a sign of
liver problems. Your healthcare provider will do blood tests to check your
liver during treatment with ALUNBRIG. Tell your healthcare provider right
away if you get new or worsening signs or symptoms, including:
* yellowing of your skin or the white part of your eyes
* dark or brown (tea color) urine
* nausea or vomiting
* pain on the right side of your stomach area
* bleed or bruise more easily than normal
* itchy skin
* decreased appetite
* feeling tired
* High blood sugar (hyperglycemia). ALUNBRIG may increase your blood sugar
levels. Your healthcare provider will do blood tests to check your blood
sugar levels before starting and during treatment with ALUNBRIG. Your
healthcare provider may need to start or change your blood sugar medicine to
control your blood sugar levels. Tell your healthcare provider right away if
you get new or worsening signs and symptoms of hyperglycemia, including:
* feeling very thirsty
* needing to urinate more than usual
* feeling very hungry
* feeling sick to your stomach
* feeling weak or tired
* feeling confused
The most common side effects of ALUNBRIG include diarrhea, fatigue, nausea,
rash, cough, muscle pain, headache, high blood pressure, vomiting and difficulty
breathing.
ALUNBRIG may cause fertility problems in males. This may affect your ability to
father a child. Talk to your healthcare provider if you have concerns about
fertility.
These are not all the possible side effects of ALUNBRIG. Call your doctor for
medical advice about side effects. You may report side effects to the FDA at
1-800-FDA-1088.
WHAT SHOULD I AVOID WHILE TAKING ALUNBRIG?
* Limit your time in the sun during treatment with ALUNBRIG and for at least 5
days after your final dose. ALUNBRIG may make your skin sensitive to
sunlight. You may burn more easily and get severe sunburns. When you are in
the sun, wear a hat and protective clothing, and use a broad-spectrum
sunscreen and lip balm with a Sun Protection Factor (SPF) of 30 or greater to
protect against sunburn.
* Avoid eating grapefruit or drinking grapefruit juice during treatment with
ALUNBRIG. Grapefruit may increase the amount of ALUNBRIG in your blood.
Before you take ALUNBRIG, tell your healthcare provider about all of your
medical conditions, including if you have lung or breathing problems, high blood
pressure, a slow heartbeat, or any vision problems, have or have had
pancreatitis, have liver problems, have diabetes mellitus or glucose
intolerance, have kidney problems or are on dialysis, are pregnant or plan to
become pregnant, or are breastfeeding or plan to breastfeed.
* ALUNBRIG can harm your unborn baby. Your healthcare provider will determine
whether or not you are pregnant before you start treatment with ALUNBRIG.
Tell your healthcare provider right away if you become pregnant during
treatment with ALUNBRIG or think you may be pregnant.
* Females who are able to become pregnant should use effective birth control
during treatment with ALUNBRIG and for at least 4 months after the final
dose of ALUNBRIG. Talk to your healthcare provider about birth control
choices that are right for you during treatment with ALUNBRIG.
* Males who have female partners who are able to become pregnant should use
effective birth control during treatment with ALUNBRIG and for at least 3
months after the final dose of ALUNBRIG.
* It is not known if ALUNBRIG passes into your breast milk. Do not breastfeed
during treatment with ALUNBRIG and for 1 week after the final dose of
ALUNBRIG.
Tell your healthcare provider about all the medicines you take, including
prescription medicines, over-the-counter medicines, vitamins, or herbal
supplements.
Please read the Patient Information in the full Prescribing Information and
discuss with your healthcare provider.
WHAT IS ALUNBRIG?
ALUNBRIG is a prescription medicine used to treat adults with non-small cell
lung cancer (NSCLC):
* that has a certain type of abnormal anaplastic lymphoma kinase (ALK) gene,
and
* that has spread to other parts of your body
It is not known if ALUNBRIG is safe and effective in children.
* Contact Us
* Terms of Use
* Privacy Notice
* Cookie Policy
* Accessibility Statement
* Site Map
TAKEDA® and the TAKEDA logo® are registered trademarks of Takeda Pharmaceutical
Company Limited. ALUNBRIG® and the ALUNBRIG logo® are registered trademarks of
ARIAD Pharmaceuticals, Inc. HERE2ASSIST® and the HERE2ASSIST logo® are
registered trademarks of Millennium Pharmaceuticals, Inc.
©2023 Takeda Pharmaceuticals U.S.A., Inc. All rights reserved.
12/23 USO-BRG-0469
This website uses cookies and other tracking technologies, and your privacy
choice is important to us. We suggest you choose "Cookie Settings" to learn more
about these cookies and to make your individualized choices.
Allow All Cookies
Cookie Settings
COOKIE PREFERENCE CENTER
When you visit our website, we store cookies on your browser to collect
information. The information collected might relate to you, your preferences or
your device, and is mostly used to make the site work as you expect it to and to
provide a more personalized web experience. However, you can choose not to allow
certain types of cookies, which may impact your experience of the site and the
services we are able to offer. Click on the different category headings to find
out more and change our default settings according to your preference. You
cannot opt-out of our First Party Strictly Necessary Cookies as they are
deployed in order to ensure the proper functioning of our website (such as
prompting the cookie banner and remembering your settings, to log into your
account, to redirect you when you log out, etc.).
More Information
Allow All
MANAGE CONSENT PREFERENCES
STRICTLY NECESSARY COOKIES
Always Active
These cookies are necessary for the website to function and cannot be switched
off in our systems. They are usually only set in response to actions made by you
which amount to a request for services, such as setting your privacy
preferences, logging in or filling in forms. You can set your browser to
block or alert you about these cookies, but some parts of the site will not then
work. These cookies do not store any personally identifiable information.
View Vendor Details
TARGETING COOKIES
Targeting Cookies
These cookies may be set through our site by our advertising partners. They may
be used by those companies to build a profile of your interests and show you
relevant adverts on other sites. They do not store directly personal
information, but are based on uniquely identifying your browser and internet
device. If you do not allow these cookies, you will experience less targeted
advertising.
View Vendor Details
PERFORMANCE COOKIES
Performance Cookies
These cookies allow us to count visits and traffic sources so we can measure and
improve the performance of our site. They help us to know which pages are the
most and least popular and see how visitors move around the site. All
information these cookies collect is aggregated and therefore anonymous. If you
do not allow these cookies we will not know when you have visited our site, and
will not be able to monitor its performance.
View Vendor Details
Back Button
VENDORS LIST
Search Icon
Filter Icon
Clear
checkbox label label
Apply Cancel
Consent Leg.Interest
checkbox label label
checkbox label label
checkbox label label
Confirm My Choices