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UTILITY

 * For Patients - Find a Clinical Trial


CANADA'S MICHAEL SMITH


GENOME SCIENCES CENTRE

Realizing the social and economic benefits of genome science. 

Research Projects


CANADA'S MICHAEL SMITH


GENOME SCIENCES CENTRE

Excellence in genomics, proteomics and bioinformatics for precision medicine.

About Us


CANADA'S MICHAEL SMITH


GENOME SCIENCES CENTRE

From Nobel roots.

Our Story


CANADA'S MICHAEL SMITH


GENOME SCIENCES CENTRE

Developing new strategies to prevent, diagnose and treat cancers and
other diseases.

Clinical Services


CANADA'S MICHAEL SMITH


GENOME SCIENCES CENTRE

Expert assistance with experimental design and biotechnology development.

Collaborative Services


CANADA'S MICHAEL SMITH


GENOME SCIENCES CENTRE

Harnessing cutting-edge genome sequencing and analytical techniques.

Technology Platform


CANADA'S MICHAEL SMITH


GENOME SCIENCES CENTRE

Enabling new ways to process, analyze and visualize genomic data.

Software Resources


CANADA'S MICHAEL SMITH


GENOME SCIENCES CENTRE

Realizing the social and economic benefits of genome science. 

Research Projects

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DEVELOPING AND DEPLOYING GENOMICS TECHNOLOGIES IN SUPPORT OF CANCER AND LIFE
SCIENCES RESEARCH.

Canada's Michael Smith Genome Sciences Centre (GSC) at BC Cancer is an
international leader in genomics, proteomics and bioinformatics for precision
medicine. By developing and deploying cutting-edge genome sequencing,
computational and analytical technology, we are creating novel strategies to
prevent and diagnose cancers and other diseases, uncovering new therapeutic
targets and helping the world realize the social and economic benefits of genome
science. 


TECHNOLOGY PLATFORM

The GSC is available to support your research. We guide experimental design,
facilitate the processing of complex biological samples and provide numerous
sequencing and bioinformatic services with the aim of making genomics accessible
to the international scientific community. Explore our technology platforms and
services, and if you have questions or would like to collaborate please fill out
our contact form or speak directly with one of our platform leaders.

The GSC is ISO27001 certified for information security management.


SCIENTIFIC RESEARCH

The 16 faculty members at the GSC have a diverse range of expertise in genomics,
bioinformatics, proteomics, epigenomics, immunogenetics, cancer biology,
computer science and software development. Together, we apply our knowledge to
advance the global understanding of cancer and other diseases with an ultimate
aim toward improving human health through disease prevention, the development of
novel diagnostic strategies and by uncovering new therapeutic approaches, all
the while helping the world to realize the social and economic benefits of
genome research.


CLINICAL PROGRAMS

The GSC is unique in that it fosters close collaborations between scientists and
clinicians, allowing for an unencumbered focus on direct translational research.
Through the Personalized OncoGenomics (POG) program, the GSC deploys whole
genome and transcriptome sequencing to inform therapeutic and management
strategies for late-stage cancer patients in real time. The GSC is also
certified by the College of American Pathologists (CAP) and the Diagnostic
Accreditation Program (DAP) to perform clinical genomic panel testing.


QUESTIONS?

Please feel free to speak with one of our Platform Leaders directly:


DIRECTORS & PLATFORM LEADERS


DR. MARCO MARRA, PHD, FRS(C), FCAHS, OBC

Director
Distinguished Scientist
mmarra@bcgsc.ca
604-675-8162
Bio


DR. STEVEN JONES, PHD, FRS(C), FCAHS

Director
Head, Bioinformatics
Distinguished Scientist
sjones@bcgsc.ca
604-877-6083
Bio


DR. MARTIN HIRST, PHD

Head, Epigenomics
Distinguished Scientist
mhirst@bcgsc.ca
604-822-6373
Bio


NEWS

Nov 19, 2021


TRANSCRIPTIONAL AND EPIGENETIC RESPONSE OF DIFFERENT CELL TYPES TO F. NUCLEATUM

Research on the role Fusobacterium nucleatum plays in cancer shows that the
transcriptome and epigenome of different host cell types are affected by the
pathogen in different ways.
 * Learn more about Transcriptional and epigenetic response of different cell
   types to F. nucleatum

Oct 28, 2021


ASSOCIATING HOST IMMUNE GENES WITH COVID-19 STATUS AND DISEASE SEVERITY

Using COVID-19 New York patient metatranscriptomics, GSC researchers René Warren
and Dr. Inanç Birol, find association between certain HLA alleles and COVID-19
disease severity
 * Learn more about Associating host immune genes with COVID-19 status and
   disease severity

Oct 27, 2021


DAP CERTIFICATION ENSURES QUALITY CLINICAL CARE

The College of Physicians and Surgeons of BC Diagnostic Accreditation Program
(DAP) gives full accreditation to GSC facilities.
 * Learn more about DAP Certification Ensures Quality Clinical Care

Oct 26, 2021


FOUR NEW MOLECULAR SUBGROUPS OF PANCREATIC NEUROENDOCRINE NEOPLASMS IDENTIFIED

Identification of four molecular subgroups of pancreatic neuroendocrine
neoplasms (PNENs) with potential implications on patient stratification and
treatment.
 * Learn more about Four New Molecular Subgroups of Pancreatic Neuroendocrine
   Neoplasms Identified




PUBLICATIONS

Integrative multi-omic analysis reveals neurodevelopmental gene dysregulation in
CIC-knockout and IDH1 mutant cells

The Journal of Pathology
Stephen D Lee, Jungeun Song, Veronique G LeBlanc, Marco A Marra

Effect of preexamination conditions in a centralized-testing model of
non-invasive prenatal screening

Clinical Chemistry and Laboratory Medicine
Chad Fibke, Sylvie Giroux, André Caron, Elizabeth Starks, Jeremy DK Parker,
Lucas Swanson, Loubna Jouan, Sylvie Langlois, Guy Rouleau, François Rousseau,
Aly Karsan

Draft genome sequence of the lichenized fungus Bacidia gigantensis

Microbiology Resource Announcements
Jessica L Allen, Steven JM Jones, R Troy McMullin

PAGINATION

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