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GROUP OF ADVANCED MATERIALS AND ORGANIC SYNTHESIS

The Group of Advanced Materials and Organic Synthesis is focused on the study of
synthesis and application of polycyclic aromatic compounds, particularly
helicenes and phenacenes. Our aim is to develop new methodologies leading to
functionalized helicenes and phenacenes with improved properties, either using
our large-scale photochemical reactors or late-stage modification approaches. On
top of that, we strive to incorporate these molecules into functional devices
ranging from sensors to various optoelectronic elements, such as organic light
emmiting diodes (OLEDs), field effect transistors (OFETs) and others.

We are an international group of scientists of different backgrounds and
together we make an interdisciplinary team focused on material science and
organic chemistry. On top of that, we participate in a number of collaborations
with both domestic and international research facilities (Institutes of the
Czech Academy of Sciences, UCT Prague, CU Prague, UP Olomouc, Uni Heidelberg,
Rennes Institute of Chemical Sciences) and industrial collaborations (Immunotech
s.r.o, Lach-ner s.r.o., Watrex Prague, s.r.o.).


SENSORS

One of our main interests lays in designing active compounds for detection of
various analytes. Our materials often exhibit a measurable change in
physico-chemical properties upon exposure to detected analyte, which allows us
to construct sensors for water, alcohols, various chiral compounds or even
biomacromolecules, such as DNA. We can use fluorescence, conductivity or even
Raman spectroscopy to serve this purpose.


CHIRAL PLASMONICS

Special place in our research of various sensors is reserved for utilization of
helicenes in chiral plasmonics. Unlike common detection methods,
Surface-enhanced Raman Spectroscopy (SERS) represents an extremely sensitive
method for detection of substrates in very low concentration. Modification of
the active surfaces with chiral helicene molecules extends the applicability of
this method also to chiral substrates.


CHIRAL ELECTRODES

Electrochemical transformations of helicenes are not common, yet we managed to
utilize the oxidative polymerization of various helicene substrates to modify
different electrodes. This method is mild and provides a uniform coating of the
electrode’s surface, while maintaining the enantiopurity of the helicene. The
result is a chiral electrode suitable for advanced aplications in
electrochemical sensing of chiral analytes.


OPTOELECTRONICS

The majority of polycyclic aromatic hydrocarbons (PAHs) have the potential to be
utilized as active materials in a variety of electronic devices, such as diodes,
transistors or solar cells. Our research in this area is focused on design of
new derivatives of helicenes and phenacenes and a study of the structure –
properties relationship, as well as improving the limiting properties, such as
low fluorescence quantum yield, crystal packing or charge mobilities.


LATEST PUBLICATIONS

 * Dyes Pigm. 2023, 210, 111039
 * Org. Lett. 2022, 24, 26, 4756–4761
 * J. Org. Chem. 2022, 87, 11, 7150–7166
 * J. Org. Chem., 2024, 7495
 * Int. J. Biol. Macromol. 2023, 125905
 * Sens. Actuators B Chem., 2023, 134332
 * Adv. Funct. Mater. 2023, 2212786
 * Dyes Pigm. 2023, 210, 111039
 * Org. Lett. 2022, 24, 26, 4756–4761
 * J. Org. Chem. 2022, 87, 11, 7150–7166
 * J. Org. Chem., 2024, 7495
 * Int. J. Biol. Macromol. 2023, 125905
 * Sens. Actuators B Chem., 2023, 134332



GAMOS is a part of the Institute of Chemical Process Fundamentals of the CAS, v.
v. i.

Group of Advanced Materials
and Organic Synthesis

Rozvojová 1/135
165 00 Prague 6 – Suchdol
Czech Republic

Email: gamos@gamoschem.com

Phone: +420 220 390 236

Institute of Chemical Process Fundamentals

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