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INTEGRATED AUTOMATION FOR CHROMATOGRAPHY AND SAMPLE PREPARATION




HARDWARE AND SOFTWARE FOR FULLY-AUTOMATED ANALYSES

Our Promises to You

iChrom Solutions will:

 * Consult with you in detail to understand thoroughly the needs of your
   laboratory and applications, regarding automation, sample preparation and
   chromatographic analysis
 * Create and specify a solution customized to those needs
 * Install and verify operation of the hardware and software according to the
   agreed specifications
 * Ensure your satisfaction with our solution as applied to your particular
   application
 * Service and support the system after installation to guarantee maximum uptime
   for your laboratory.

Laboratory Challenges Today
 * Too many samples for laboratory capacity
 * Too little time to meet laboratory productivity goals
 *  Inconsistent data reliability due to multiple operators and variables
 * Complex, excessive sample manipulation with current sample processing
 * Analyte loss resulting from sample transfer, dry-down, reconstitution, other
   steps
 * Sensitivity challenges due to difficulty of assays and analyte loss (as
   above)
 * Underusage of expensive analyzers (e.g., mass spectrometers)

In addition:

 * Many clients are unaware that these issues can be fixed
 * Many clients are unsure what solutions exist to address the issues
 * Many clients appreciate guidance on even the first steps to solve these
   problems




IMAGINE THE DIFFERENCE…

 * FULLY-AUTOMATED SAMPLE PREP AND ANALYSIS (CONTINUOUS OPERATION)
   
   

 * RELIABILITY OF DECADES-TESTED INSTRUMENT-BASED (VERSUS HUMAN-BASED) PROCESSES
   
   

 * EXCESS CAPACITY – TO HANDLE NEW LAB GROWTH OR “STAT” SITUATIONS
   
   

 * SUPERIOR – YET SIMPLER FOR THE USER - SAMPLE CLEANUP DUE TO ADVANCED ON-LINE
   TECHNOLOGY
   
   


ADD TO THIS – A CREDIBLE AND TRUSTWORTHY PARTNER WHO GUARANTEES YOUR SUCCESS
WITH OUR PROVIDED-SOLUTIONS, TO MEET YOUR OBJECTIVES.


THIS IS WHAT ICHROM SOLUTIONS MEANS TO YOU.

Who is iChrom Solutions?

We are a knowledgeable and experienced integrator of systems, modules, and
software for sample preparation, on-line SPE, HPLC and UHPLC. iChrom has over 16
years of working closely with laboratories to create optimum, integrated
automation solutions for their technology needs, applications, and budgets.

What do we provide?

iChrom Solutions provides hardware, software, guidance, service, and support for
integrated laboratory automation – focusing on full-automation of sample
preparation and UHPLC separations.


OUR SUPPLIERS

iChrom Solutions is the North American exclusive dealer for a number of
instrument and software solutions (for the complete list, click the Products tab
in the main menu above.). We work only with long-established, world-class
technology suppliers of UHPLC pumps, autosamplers, automated on-line SPE
equipment, mass spectrometers, accessories, control software, and other modules.

SupplierProductsAbout the Supplier SupplierAxel Semrau, GmbH &
Co.ProductsCHRONECT Symbiosis Systems, CHRONECT Modules, CHRONOS SoftwareAbout
the SupplierFor more than 35 years Axel Semrau has been active in development,
distribution and support for sample preparation and chromatography, chemical
synthesis, and application-optimized workstations. The company develops its own
hardware and software to provide unique and robust solutions for sample prep,
chromatography, and instrument control.SupplierKNAUER Wissenschaftliche Geräte
GmbHProductsAnalytical HPLC/UHPLC Chromatography SystemsAbout the SupplierBased
in Berlin, KNAUER has been serving the sciences since 1962. Knauer develops and
manufactures scientific instruments of superior quality for liquid
chromatography systems and components, including:
 * Analytical HPLC / UHPLC
 * Preparative HPLC
 * Fast protein liquid chromatography (FPLC)
 * Multi-Column Chromatography / SMB
 * Osmometry

SupplierMicrosaic SystemsProducts4500 MiD® miniature/portable quadrupole mass
spectrometerAbout the SupplierMicrosaic Systems plc (AIM: MSYS) develops
chip-based, bench-top and point-of-analysis mass spectrometry (MS) instruments
that are designed to improve the efficiency of pharmaceutical R&D and
manufacturing. Microsaic works with established global life science companies
for new solutions to help develop small molecule and novel biologic (peptides,
antibodies) medicines.
Microsaic’s core product, the 4500 MiD®, is a robust and compact MS system,
retaining the functionality of larger conventional MS systems; yet is easier to
use by non-specialists, consumes less energy and has lower running costs.

 * 
 * 
 * 

SupplierProductsAbout the Supplier Axel Semrau, GmbH & Co.CHRONECT Symbiosis
Systems, CHRONECT Modules, CHRONOS softwareFor more than 35 years Axel Semrau
has been active in development, distribution and support for sample preparation
and chromatography, chemical synthesis, and application-optimized workstations.
The company develops its own hardware and software to provide unique and robust
solutions for sample prep, chromatography, and instrument control.KNAUER
Wissenschaftliche Geräte GmbHAnalytical HPLC/UHPLC Chromatography SystemsBased
in Berlin, KNAUER has been serving the sciences since 1962. Knauer develops and
manufactures scientific instruments of superior quality for liquid
chromatography systems and components, including:
 * Analytical HPLC / UHPLC
 * Preparative HPLC
 * Fast protein liquid chromatography (FPLC)
 * Multi-Column Chromatography / SMB
 * Osmometry

Microsaic Systems4500 MiD® miniature/portable quadrupole mass
spectrometerMicrosaic Systems plc (AIM: MSYS) develops chip-based, bench-top and
point-of-analysis mass spectrometry (MS) instruments that are designed to
improve the efficiency of pharmaceutical R&D and manufacturing. Microsaic works
with established global life science companies for new solutions to help develop
small molecule and novel biologic (peptides, antibodies) medicines.
Microsaic’s core product, the 4500 MiD®, is a robust and compact MS system,
retaining the functionality of larger conventional MS systems; yet is easier to
use by non-specialists, consumes less energy and has lower running costs.

Why iChrom Solutions?
Our Markets/Industries
On-Line SPE
UHPLC
Service/Support
Why iChrom Solutions?

We are specialists at combining best-in-class modules and sub-systems into
fully-integrated, fully-automated solutions. Our approach is based on
comprehensive, thorough discussions with end users, client technology experts,
lab managers, and financial buyers - to ensure creation of a solution that meets
the needs of all stakeholders on the client side.

Our Markets/Industries

We have integrated, fully-automated system placements in virtually every major
market category of sample prep/liquid chromatography, including:

 * Pharmaceutical
 * Clinical
 * Forensic
 * Food/Agriculture
 * Environmental

In addition, our systems are used for critical reference applications, including
PFOS/PFOA as performed in government and environmental laboratories, and provide
full capabilities to address current applications of interest; for example,
those facing drug-testing laboratories such as opioid abuse/pain management,
recreational and designer drugs, novel designer cannabinoids, and many others.

On-Line SPE

Many companies offer automation for various sample preparation processes.
Perhaps the most common question we receive at iChrom Solutions is, “What makes
on-line SPE so special? The answer has a few main parts:

 1. SPE in general is widely-accepted as the highest-selectivity technique for
    maximum sample cleanup (i.e., resulting in the purest extracts with the
    fewest interferences). Because it is a chromatographic technique, SPE can
    take advantage of slight molecular differences in sample components to
    isolate them from one another, unlike liquid/liquid extraction or protein
    precipitation.
 2. Because on-line SPE cartridges (CHROSPE) are processed under pressure (like
    HPLC columns), it is possible to use microparticulate packings, which means
    a) higher-efficiency elutions with smaller volumes, b) higher capture
    efficiencies, requiring less sorbent than off-line approaches, c)
    compatibility for direct elution from the extraction cartridge into the
    analytical column. This means zero analyte loss due to dry-downs,
    reconstitutions, vessel transfers, etc.
 3. Our latest on-line SPE technology is even compatible with UHPLC analyses,
    allowing cartridge elutions at up to 1,000 bar (~15,000 psi). Try doing that
    with an off-line column!
 4. Full automation. In many cases the user simply places the raw liquid sample
    into the sample-handler vial, and pushes “go”. The system takes it from
    there, from further raw sample processing (e.g., internal standard addition,
    dilute and mix, etc.), to complete extraction protocols on the
    high-performance cartridge, through the analytical process. All with
    integrated control via CHRONOS software…including interface with the mass
    spectrometric detector.

UHPLC

UHPLC is the unquestioned leader in advanced liquid chromatography separation
techniques. The high-pressures provided by UHPLC pumps (up to ~18,000 psi/~1200
bar) allow for columns with sub-2 micron particles for previously-unseen
efficiencies and separation speeds. iChrom Solutions provides complete UHPLC
systems with advanced pumps and highly-configurable, flexible autosamplers to
perform the necessary additional tasks needed for integration with on-line SPE
modules (e.g., handling not only finished, but raw samples).

Service/Support

At iChrom Solutions we pride ourselves on standing by our customers via our
dedicated hardware/software service and support. In addition to service upon
request, we offer a number of service contracts with flexible options to meet
your specific laboratory needs.

For details on our service programs see below.


PLEASE SELECT THE PRODUCTS OR RESOURCES TABS IN THE MAIN MENU ABOVE TO VIEW THE
WIDE SELECTION OF PRODUCT AND APPLICATION SOLUTIONS WE OFFER.



Mailing Address
542 Cross Keys Rd. Suite # 3-376
Sicklerville, NJ 08081-4367

(609) 799-7250

(609) 799-8250

info@ichrom.com


SITE LINKS

 * Home
 * Service/Support
 * Clarity Software
   * Clarity Overview/Features
   * Clarity Screenshots
 * CHRONECT Symbiosis
   * Introduction to CHRONECT Symbiosis
   * CHRONECT Symbiosis Basic
   * CHRONECT Symbiosis Plus
   * CHRONECT Symbiosis Advanced
 * CHRONECT Symbiosis Modules
 * CHROSPE Cartridges
 * Microsaic Mass Spectrometry
   * MiD® 4500 Mass Spectrometer
   * MiDas™ Compact Sampling Interface/Masscape Software
 * HPLC/Dosing/Metering
   * Dosing/Metering Compact Pumps
 * Osmometry
   * K7400-S Semi-Micro Osmometer
 * DBS Autosampler
 * Resources
   * Mass Spectrometry
 * Our Company
   * About IChrom
   * Legacy Products
 * Store
 * Contact Us
 * Terms of Use


QUICK LINKS

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