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REIMAGINING THE INFRASTRUCTURE OF CANCER CARE


WE PROVIDE SOLUTIONS ACROSS THE INDUSTRY TO LEARN FROM AND IMPROVE EVERY
PERSON’S EXPERIENCE WITH CANCER. SEE HOW WE’RE:

 * Designing and operating better clinical trials
 * Accelerating drug development and access
 * Powering smarter care


TRANSFORMING POSSIBILITIES INTO RESULTS


FEATURED PRODUCTS & SOLUTIONS

Clinicians, researchers, and regulators rely on FLATIRON HEALTH® technology and
evidence to learn faster and power smarter care for every patient.


ACHIEVE YOUR ONCOLOGY REAL-WORLD EVIDENCE GOALS FASTER AND MORE EFFICIENTLY

Generate robust evidence and insights by partnering with Flatiron's expert team
of clinicians, scientists, and health data analysts.

See how


— HEAR FROM OUR CUSTOMERS

FIT-FOR-PURPOSE RWE SOLUTIONS

> Flatiron was chosen because it’s fit for purpose. You have the right
> population and good sample size with data for the endpoint, which is overall
> response rate. A key learning is you need to choose a database with good
> quality.

Huamao Mark Lin, PhDSenior Director, Global Evidence and Outcome Research, Solid
TumorTakeda Oncology


— BY THE NUMBERS

3.5 MILLION+

3.5 million+ patient records de-identified and available for research


DISCOVER A FASTER, MORE EFFICIENT PATH TO CLEAN STUDY DATA

One of the industry's first EHR-to-EDC connectors, Flatiron Clinical Pipe™ helps
create a new trial experience.

See how


— HEAR FROM OUR CUSTOMERS

TRANSFER TRIAL DATA FASTER

> Working with partners like Flatiron and technology like [Flatiron] Clinical
> Pipe and Flatiron Vessel has been an excellent opportunity for us to really
> build processes and systems around the technology that is available today and
> get those technologies to work together.

Dannelle M. Palmer, MBA, PMPCOOOncoBay Clinical


— BY THE NUMBERS

85 SITES AND COUNTING

Flatiron Clinical Pipe™ is live at 85 sites and counting


UNLEASH PRECISION ONCOLOGY WITH OUR CUSTOMIZABLE CLINICAL DECISION SUPPORT
PLATFORM

Improve the patient experience, streamline operations, and increase revenue with
instinctive workflows, up-to-date treatment guidelines, and actionable data.

See how


— HEAR FROM OUR CUSTOMERS

EXPAND INSIGHTS AT THE POINT OF CARE

> Flatiron Assist is a decision support tool that helps us choose and find the
> right regimens for our patients, stay within NCCN guidelines, and the
> treatment plans are very robust and customizable.

Nick Bouchard, PharmDDirector of Pharmacy ServicesHematology Oncology Associates
of Central New York


— BY THE NUMBERS

44% REDUCTION

44% reduction in the number of unique regimens ordered across cancer centers
using Flatiron Assist™




SOLVING PROBLEMS FOR TEAMS ACROSS THE ONCOLOGY ECOSYSTEM


HOW WE PARTNER

Transforming cancer care takes all of us. Our vision is to build a world where
technology and science close the gap between care and research.

ACADEMIC MEDICAL CENTERS

Enable quality care by providing evidence-based treatment options to clinicians
and run more efficient clinical research by surfacing trial-eligible patients
directly in the EHR. Once enrolled, digitally transfer relevant trial data from
the EHR to downstream systems.



HOW WE PARTNER

EHR-to-EDCClinical Decision SupportClinical Trial Recruitment

HEOR & RWE TEAMS

Design and execute real-world studies including comparative effectiveness,
modeling long-term survival, and analyzing treatment patterns to provide
insights into a treatment's long-term effectiveness as well as support market
access and reimbursement decisions.



HOW WE PARTNER

RWE ServicesReal-World DataProspective Evidence Generation

RESEARCH & EARLY DEVELOPMENT TEAMS

Quicken drug discovery and development by linking genomics data with clinical
outcomes to help assess unmet need, generate hypotheses about biomarker
resistance alterations and co-alterations, and inform decision-making.



HOW WE PARTNER

RWE ServicesReal-World Data

CLINICAL OPERATIONS TEAMS

Accelerate clinical research timelines, increase trial participant
representativeness, and execute trials more efficiently to get your treatment to
market sooner.



HOW WE PARTNER

EHR-to-EDCClinical Trial Diversity PlanningProspective Evidence
GenerationProtocol OptimizationClinical Trial Patient Identification

REGULATORY AFFAIRS TEAMS

Leverage Flatiron's extensive experience with regulatory-grade real-world data
to develop regulatory strategies, prepare evidence packages for approval and
post-market requirements, and lead regulatory engagement.



HOW WE PARTNER

Real-World DataRWE ServicesValue and Market Access

COMMUNITY ONCOLOGY PRACTICES

Deliver quality patient care with a cancer-specific EHR and surface
evidence-based treatment options. For practices that support research, save time
and gain accuracy through data-backed identification of eligible trial patients
in the EHR and digitally transfer relevant study data seamlessly between the EHR
and EDC.



HOW WE PARTNER

EHRClinical Decision SupportValue-Based CareClinical Trial RecruitmentEHR-to-EDC

MARKET ACCESS TEAMS

Demonstrate a cancer drug's value to payers and Health Technology Assessment
(HTA) bodies to accelerate access to life-extending cancer treatments worldwide
and ensure reimbursement and optimal pricing.



HOW WE PARTNER

Value and Market AccessRWE ServicesReal-World Data

PHARMACOVIGILANCE & EPIDEMIOLOGY TEAMS

Monitor and assess the safety of cancer drugs, leveraging retrospective and
prospective real-world studies to identify adverse events, detect safety
signals, and provide insights into the long-term safety profile of cancer drugs
beyond clinical trials.



HOW WE PARTNER

Real-World DataProspective Evidence Generation

CONTRACT RESEARCH ORGANIZATIONS

Optimize clinical trials with our novel, interoperable technology. Flatiron's
products provide CROs with a streamlined, technology-driven approach to
accelerate trial timelines, make data-backed decisions, and create efficiencies,
giving you more confidence in trial success.



HOW WE PARTNER

EHR-to-EDCProtocol OptimizationClinical Trial Patient Identification

CLINICAL DEVELOPMENT TEAMS

Utilize deep real-world data to assess the impact of inclusion/exclusion
criteria and enable adjustments based on diversity goals and enrollment
timelines through tailored protocol analyses that include insights on patient
characteristics and expected outcomes.



HOW WE PARTNER

Clinical Trial Diversity PlanningReal-World DataRWE ServicesProspective Evidence
GenerationProtocol OptimizationClinical Trial Patient Identification

PORTFOLIO STRATEGY AND COMMERCIAL TEAMS

Generate fast insights to identify portfolio gaps and opportunities, refine your
commercial strategy and provide real-time line of sight into the launch
performance and uptake with tailored RWE solutions.



HOW WE PARTNER

Real-World DataRWE Services

MEDICAL AFFAIRS TEAMS

Leverage Flatiron's RWE solutions to generate insights for the scientific
community, regulatory agencies, healthcare professionals, and the broader market
to ensure that new drugs are developed, communicated, and utilized effectively
and ethically.



HOW WE PARTNER

Real-World DataRWE ServicesProspective Evidence Generation




NEW AND NOTEWORTHY


FEATURED NEWS AND INSIGHTS

Explore the latest insights, research, and stories from Flatiron’s global team.

 * NEW ANALYSIS SHOWS REAL-WORLD EVIDENCE COULD STREAMLINE AND ACCELERATE AT
   LEAST ONE IN FOUR POSTMARKETING STUDIES
   
   We tend to think of clinical trials as preambles to the drug approval
   process. A life science company develops a new drug, runs clinical trials to
   study its effects, and if everything goes well, submits it for approval.
   
   Read more

 * ADVANCING EQUITY IN CANCER CARE: UNVEILING INSIGHTS FROM THE 2023 REAL-WORLD
   DATA IMPACT AWARD
   
   In its fourth year, the Real-World Data Impact Award, jointly presented by
   the American Cancer Society and Flatiron Health, offers researchers $75,000,
   access to one of Flatiron’s 20+ EDMs, and the support of Flatiron’s and the
   American Cancer Society’s clinical and methodological experts to answering
   pressing, clinically-relevant questions focused on inequities in cancer care.
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   Read more

 * THE ASSOCIATION OF CANCER CARE CENTERS AND FLATIRON HEALTH ANNOUNCE A
   STRATEGIC COLLABORATION TO IMPROVE STUDY DATA CAPTURE
   
   Partnership to enable cancer care centers to improve access and efficiency of
   clinical studies and research
   
   Read more

 * FLATIRON HEALTH ANNOUNCES RESEARCH TO BE PRESENTED AT ISPOR 2024
   
   Advancing oncology research for precision medicine and equity in patient care
   
   Read more

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