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Institute of Molecular Vascular Medicine
TUM School of Medicine and Health
Technische Universität München
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 * 39

Welcome to the Institute of Molecular Vascular Medicine

The Institute of Molecular Vascular Medicine is located on TUM’s Biederstein
Campus along the scenic English Garden in the Schwabing district of Munich
(Münchner Freiheit, U3/U6 subway lines). Our research focuses on unraveling the
potential of non-coding RNAs in a translational cardiovascular context. 

We are members of the DZHK partner site Munich (Munich Heart Alliance), the
DFG-sponsored Collaborative Research Center (CRC) 1123 “Atherosclerosis -
Mechanisms and networks of novel therapeutic targets,” the TRR 267 on
“Non-coding RNAs in the cardiovascular system,” the lighthouse project of the
Freestate of Bavaria “DigiMed Bayern,” as well as the CNATM Clusters4Future on
RNA-based therapies supported by the German Ministry for Education and Research
(BMBF). 

Mission

Our mission is to pioneer innovative approaches for stabilizing vulnerable
atherosclerotic plaques in carotid arteries and halting the progression of AAA
disease. Through comprehensive research utilizing human biobank materials,
preclinical models, and cutting-edge organoid systems, we aim to elucidate the
molecular mechanisms and genetic factors governing the fate of vascular smooth
muscle cells within fibrous caps of advanced lesions. Our focus extends to
understanding the roles of non-coding RNAs, including microRNAs, long non-coding
RNAs, and circular RNAs, in cardiovascular homeostasis and disease development.
By developing novel models and treatment strategies, we strive to translate our
findings into effective therapeutic interventions that improve patient outcomes
and reduce the burden of cardiovascular disease.

Vision

 * Become a global leader in cardiovascular research, recognized for pioneering
   approaches to understanding vascular diseases.
 * Foster interdisciplinary collaborations to advance knowledge of molecular
   mechanisms underlying atherosclerotic plaques and AAA disease.
 * Lead the development of personalized therapeutic interventions such as
   multi-omics data tailored to target non-coding RNAs and other key molecular
   regulators.
 * Transform the landscape of cardiovascular medicine by translating innovative
   research findings into effective clinical treatments.

 

read more
Dr. Lars Mägdefessel
Institute Director
Dr. Lars Mägdefessel
Institute Director
lars.maegdefessel@tum.de
+49 89 4140 3490

Institut für Molekulare Vaskuläre Medizin
 
Kontakt:
Tel.: +49 89 41403492





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