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GENETIC TESTING BEFORE IMMUNOSUPPRESSING RX COULD CURB RARE BRAIN INFECTION RISK
PREMIUM

While four genetic mutations have been associated with the risk of developing
PML, there is not consensus on which drugs merit preventive screening.


TAPESTRY STUDY RESULTS FUEL CALLS FOR UNIVERSAL GENETIC TESTING FOR HEREDITARY
CANCER RISK
PREMIUM

An analysis of whole-exome sequencing results presented at AACR suggests many
people with hereditary cancer risk variants don't fall under current NCCN
guidelines.


C2I GENOMICS EXPANDS DATA ON WHOLE-GENOME SEQUENCING MRD TEST IN COLON, LUNG
CANCER
PREMIUM

At AACR, the company highlighted new prospective and retrospective data that it
believes helps set its platform apart from other available ctDNA technologies.


NEXT WAVE OF KRAS G12C INHIBITORS MAY ADDRESS LIMITS OF FIRST-GEN DRUGS, AACR
STUDIES SHOW
PREMIUM

Early studies of KRAS inhibitors from Loxo Oncology, Genentech, and Innovent
suggest newer drugs have activity in KRAS G12C-resistant patients.


MERCK TO ACQUIRE PROMETHEUS BIOSCIENCES FOR $10.8B

Prometheus' lead candidate is PRA023, a monoclonal antibody it's testing to
treat ulcerative colitis, Crohn's disease, and other autoimmune conditions.


NKGEN BIOTECH TO GO PUBLIC THROUGH SPAC MERGER

The firm's lead product candidate is an autologous cell therapy under
investigation as a treatment for Alzheimer's disease and refractory solid
tumors.
Business, Policy & Funding


 * GENSIGHT BIOLOGICS WITHDRAWS EMA APPLICATION FOR INHERITED VISION LOSS GENE
   THERAPY


 * NMPA CLEARS CARSGEN THERAPEUTICS' IND FOR CAR T-CELL THERAPY IN
   CLDN18.2-POSITIVE PANCREATIC CANCER


 * IN BRIEF THIS WEEK: KINNATE BIOPHARMA, HUIDAGENE THERAPEUTICS, EPIC BIO,
   DANTE GENOMICS


 * GENEURO TESTING EFFICACY OF ANTIBODY TEMELIMAB IN LONG COVID PATIENTS WITH
   W-ENV PROTEIN
   PREMIUM


 * VENTUS RECEIVES GRANT TO DEVELOP PET TRACER FOR PARKINSON'S DISEASE-LINKED
   BIOMARKER

Precision Oncology


 * GENSIGHT BIOLOGICS WITHDRAWS EMA APPLICATION FOR INHERITED VISION LOSS GENE
   THERAPY


 * NMPA CLEARS CARSGEN THERAPEUTICS' IND FOR CAR T-CELL THERAPY IN
   CLDN18.2-POSITIVE PANCREATIC CANCER


 * GENEURO TESTING EFFICACY OF ANTIBODY TEMELIMAB IN LONG COVID PATIENTS WITH
   W-ENV PROTEIN
   PREMIUM


 * MICROBIOME STARTUP BIOMED TECHNOLOGY RAISES $2M IN SEED ROUND


 * TAPESTRY STUDY RESULTS FUEL CALLS FOR UNIVERSAL GENETIC TESTING FOR
   HEREDITARY CANCER RISK
   PREMIUM

Precision Medicine Trends


 * CLINICAL CONCERNS DOMINATE MULTI-CANCER EARLY DETECTION DEBATE AT AACR
   PREMIUM


 * JANUX THERAPEUTICS BEGINS PHASE I TRIAL OF T-CELL ENGAGER THERAPY IN
   EGFR-POSITIVE SOLID TUMORS


 * C2I GENOMICS EXPANDS DATA ON WHOLE-GENOME SEQUENCING MRD TEST IN COLON, LUNG
   CANCER
   PREMIUM


 * LYNPARZA, CERALASERTIB COMBO TRIAL PROVIDES CLUES ON BIOMARKERS OF RESPONSE
   IN PEDIATRIC CANCER
   PREMIUM


 * SKYLINEDX, NERACARE PARTNERING ON PROTEOMIC TEST FOR MELANOMA

Disease Areas


 * GENSIGHT BIOLOGICS WITHDRAWS EMA APPLICATION FOR INHERITED VISION LOSS GENE
   THERAPY


 * NMPA CLEARS CARSGEN THERAPEUTICS' IND FOR CAR T-CELL THERAPY IN
   CLDN18.2-POSITIVE PANCREATIC CANCER


 * JANUX THERAPEUTICS BEGINS PHASE I TRIAL OF T-CELL ENGAGER THERAPY IN
   EGFR-POSITIVE SOLID TUMORS


 * EARLY FUNCTIONAL PRECISION MEDICINE APPROACHES SHOW POTENTIAL TO IMPROVE
   PATIENT OUTCOMES
   PREMIUM


 * GENEURO TESTING EFFICACY OF ANTIBODY TEMELIMAB IN LONG COVID PATIENTS WITH
   W-ENV PROTEIN
   PREMIUM

Breaking News


 * GENSIGHT BIOLOGICS WITHDRAWS EMA APPLICATION FOR INHERITED VISION LOSS GENE
   THERAPY


 * NMPA CLEARS CARSGEN THERAPEUTICS' IND FOR CAR T-CELL THERAPY IN
   CLDN18.2-POSITIVE PANCREATIC CANCER


 * IN BRIEF THIS WEEK: KINNATE BIOPHARMA, HUIDAGENE THERAPEUTICS, EPIC BIO,
   DANTE GENOMICS


 * JANUX THERAPEUTICS BEGINS PHASE I TRIAL OF T-CELL ENGAGER THERAPY IN
   EGFR-POSITIVE SOLID TUMORS


 * VENTUS RECEIVES GRANT TO DEVELOP PET TRACER FOR PARKINSON'S DISEASE-LINKED
   BIOMARKER


 * SKYLINEDX, NERACARE PARTNERING ON PROTEOMIC TEST FOR MELANOMA



What's Popular?


 1. TAPESTRY STUDY RESULTS FUEL CALLS FOR UNIVERSAL GENETIC TESTING FOR
    HEREDITARY CANCER RISK
    PREMIUM


 2. IN BRIEF THIS WEEK: KINNATE BIOPHARMA, HUIDAGENE THERAPEUTICS, EPIC BIO,
    DANTE GENOMICS


 3. GENEURO TESTING EFFICACY OF ANTIBODY TEMELIMAB IN LONG COVID PATIENTS WITH
    W-ENV PROTEIN
    PREMIUM


 4. EARLY FUNCTIONAL PRECISION MEDICINE APPROACHES SHOW POTENTIAL TO IMPROVE
    PATIENT OUTCOMES
    PREMIUM


 5. C2I GENOMICS EXPANDS DATA ON WHOLE-GENOME SEQUENCING MRD TEST IN COLON, LUNG
    CANCER
    PREMIUM




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