www.channelnewsasia.com Open in urlscan Pro
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Asia


SINOPHARM'S COVID-19 VACCINE REMAINED ACTIVE AGAINST SOUTH AFRICA VARIANT,
EFFECT REDUCED: STUDY

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SINOPHARM'S COVID-19 VACCINE REMAINED ACTIVE AGAINST SOUTH AFRICA VARIANT,
EFFECT REDUCED: STUDY



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Asia


SINOPHARM'S COVID-19 VACCINE REMAINED ACTIVE AGAINST SOUTH AFRICA VARIANT,
EFFECT REDUCED: STUDY

FILE PHOTO: A sign of Sinopharm is seen at the 2020 China International Fair for
Trade in Services (CIFTIS), following the COVID-19 outbreak, in Beijing, China
September 5, 2020. REUTERS/Tingshu Wang
03 Feb 2021 12:34PM


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BEIJING: Two COVID-19 vaccines from Chinese companies including Sinopharm
triggered immunity against a highly transmissible coronavirus variant first
found in South Africa, but their effect appeared weaker, a small-sample lab
study released on Tuesday (Feb 2) showed.

Variants of the virus have stirred concern that they might weaken effects of
vaccines and treatments developed prior to their emergence.


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READ: PFIZER-BIONTECH SAY COVID-19 VACCINE WORKS AGAINST UK, SOUTH AFRICA VIRUS
MUTATIONS

Twelve serum samples each taken from recipients of two vaccines developed by a
subsidiary of China National Pharmaceutical Group (Sinopharm) and a unit of
Chongqing Zhifei Biological Products retained neutralising activity against the
South African variant, their researchers said in a paper.

The paper was written by researchers from Sinopharm-affiliated Beijing Institute
of Biological Products, the Institute of Microbiology of Chinese Academy of
Sciences, which is co-developing a candidate with Zhifei unit, and two other
Chinese agencies.


READ: WHO SAYS VACCINE MAKERS WORKING NON-STOP TO PLUG SUPPLY GAP, URGES
PATIENCE


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READ: MODERNA SAYS VACCINE EFFECTIVE AGAINST COVID-19 VARIANTS; TESTING EXTRA
BOOSTER FOR SOUTH AFRICAN STRAIN


However, the samples' activity against the variant was weaker than against the
original virus and another variant currently spreading globally, according to
the paper published on website BioRxiv ahead its peer-review. 

The activity reduction "should be taken into account for its impact for the
clinical efficacy of these vaccines," they said.

The Sinopharm vaccine is approved in China for general public use and is also
used in several other countries including the United Arab Emirates. The Zhifei
shot is in late-stage clinical trials in China and overseas.


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Preliminary clinical trial data on vaccines from Novavax Inc and Johnson &
Johnson also showed they were significantly less effective at preventing
COVID-19 in trial participants in South Africa, where the potent new variant is
widespread.


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DEVELOPMENTS

Download our app or subscribe to our Telegram channel for the latest updates on
the coronavirus outbreak: https://cna.asia/telegram

Source: Reuters/ga


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 * coronavirus
 * vaccine
 * China
 * Sinopharm


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